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公开(公告)号：US20150251153A1
公开(公告)日：2015-09-10
申请号：US14718579
申请日：2015-05-21
Applicant: H R D Corporation
Inventor： Abbas HASSAN , Rayford G. ANTHONY , Gregory BORSINGER , Aziz HASSAN , Ebrahim BAGHERZADEH
CPC classification number: B01J19/1806 , B01F7/00766 , B01F7/00791 , B01F13/1013 , B01F13/1016 , B01J8/20 , B01J8/22 , B01J10/007 , B01J14/005 , B01J19/008 , B01J2219/00105 , B01J2219/1941 , C07C29/04 , C07C29/106 , C07C45/34 , C07C45/39 , C07C51/265 , C07C67/08 , C07C209/36 , C07C2601/16 , C12C11/02 , C07C31/22 , C07C31/225 , C07C35/14 , C07C31/202 , C07C31/207 , C07C31/205 , C07C47/06 , C07C49/04 , C07C49/08 , C07C63/06 , C07C69/003 , C07C211/46 , C07C211/50 , C07C69/14
Abstract: A reactor comprising at least one contact surface made from, coated with, or impregnated by a catalyst, wherein the contact surface comprises a sintered metal or a ceramic, and wherein the reactor is configured to subject a reactant stream to shear. A system for carrying out a heterogeneously catalyzed reaction, the system comprising a reactor as described above and a pump configured for delivering reactants to the at least one reactor. A method for carrying out a heterogeneously-catalyzed reaction by introducing reactants into a reactor comprising at least one contact surface made from, coated with, or impregnated by a catalyst under conditions which promote production of a desired product, wherein the contact surface comprises a sintered metal or a ceramic, and forming a dispersion of reactants within the reactor, wherein the dispersion comprises droplets or gas bubbles of reactant with an average diameter of less than about 5 μm.
Abstract translation: 一种反应器，包括由催化剂制成，涂覆或浸渍的至少一个接触表面，其中所述接触表面包括烧结金属或陶瓷，并且其中所述反应器构造成使反应物流受到剪切。 一种用于进行非均相催化反应的系统，该系统包括如上所述的反应器和构造成用于将反应物输送到至少一个反应器的泵。 一种通过将反应物引入反应器中进行非均相催化反应的方法，所述反应器包括在促进所需产物生产的条件下由催化剂制备，涂覆或浸渍的至少一个接触表面，其中所述接触表面包括烧结 金属或陶瓷，并且在反应器内形成反应物的分散体，其中分散体包含平均直径小于约5μm的反应物的液滴或气泡。
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公开(公告)号：US20150068953A1
公开(公告)日：2015-03-12
申请号：US14463858
申请日：2014-08-20
Applicant: H R D Corporation
Inventor： Abbas HASSAN , Aziz HASSAN , Rayford G. ANTHONY , Gregory G. BORSINGER
CPC classification number: C10G49/22 , B01F7/00766 , B01F13/1016 , B01J8/222 , B01J19/1806 , B01J2208/00283 , B01J2219/0011 , B01J2219/00189 , C01B3/22 , C01B3/24 , C01B3/26 , C01B3/50 , C01B2203/0272 , C01B2203/0277 , C01B2203/10 , C01B2203/1041 , C01B2203/1235 , C01B2203/1241 , C01B2203/1247 , C01B2203/1276 , C01B2203/148 , C10G2/30 , C10G2/342 , C10G9/00 , C10G45/00 , C10G45/02 , C10G45/12 , C10G47/00 , C10G47/24 , C10G49/10 , C10G49/20 , C10G50/00
Abstract: Herein disclosed is a method of producing value-added product from light gases, the method comprising: (a) providing light gases comprising at least one compound selected from the group consisting of C1-C6 compounds and combinations thereof; (b) intimately mixing the light gases with a liquid carrier in a high shear device to form a dispersion of gas in the liquid carrier, wherein the dispersion is supersaturated with the light gases and comprises gas bubbles at least some of which have a mean diameter of less than or equal to about 5 micron(s); (c) allowing the value-added product to form and utilizing vacuum to extract unreacted light gases from the liquid carrier; (d) extracting the value-added product; wherein the value-added product comprises at least one component selected from the group consisting of higher hydrocarbons, hydrogen, olefins, alcohols, aldehydes, and ketones. A system for producing value-added product from light gases is also disclosed.
Abstract translation: 本文公开了一种从轻质气体生产增值产品的方法，该方法包括：（a）提供包含至少一种选自C1-C6化合物及其组合的化合物的轻质气体; （b）将轻质气体与高剪切装置中的液体载体紧密混合以形成液体载体中的气体分散体，其中该分散体与轻质气体过饱和，并且包括气泡，其中至少一些具有平均直径 小于或等于约5微米; （c）允许增值产品形成和利用真空从液体载体中提取未反应的轻质气体; （d）提取增值产品; 其中所述增值产物包含至少一种选自高级烃，氢，烯烃，醇，醛和酮的组分。 还公开了一种从轻质气体生产增值产品的系统。
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公开(公告)号：US20140256601A1
公开(公告)日：2014-09-11
申请号：US14200444
申请日：2014-03-07
Applicant: H R D Corporation
Inventor： Abbas HASSAN , Aziz HASSAN , Gregory G. BORSINGER
CPC classification number: B01F15/065 , B01F3/2078 , B01F7/00766 , B01F13/1016 , C09K8/035
Abstract: Herein disclosed is a method for producing a predispersed wax product comprising: operating a high shear device having at least one rotor/stator, configurable for a shear rate of at least 20,000 s−1; introducing wax and a carrier liquid into said high shear device; and forming a dispersion of wax in a carrier liquid, wherein the wax comprises globules with an average diameter less than 5 mm.
Abstract translation: 本文公开了一种用于生产预分散蜡产品的方法，包括：操作具有至少一个转子/定子的高剪切装置，其可配置为至少20,000s -1的剪切速率; 将蜡和载液引入所述高剪切装置中; 以及在载体液体中形成蜡的分散体，其中蜡包含平均直径小于5mm的小球。
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公开(公告)号：US20130072718A1
公开(公告)日：2013-03-21
申请号：US13679839
申请日：2012-11-16
Applicant: H R D Corporation
Inventor： Abbas HASSAN , Ebrahim BAGHERZADEH , Rayford G. ANTHONY , Gregory G. BORSINGER , Aziz HASSAN
IPC: C07C51/56
CPC classification number: C07C51/56 , B01F7/00766 , B01F13/1013 , B01F13/1016 , B01J8/025 , B01J8/20 , B01J19/0066 , B01J19/1806 , B01J2219/00006 , B01J2219/00779 , Y02P20/582 , C07C53/12
Abstract: A method for producing acetic anhydride that includes operating a high shear device at a shear rate of greater than about 20,000 s−1, wherein the high shear device is configured with a rotor and a stator; forming in the high shear device an emulsion having a liquid catalyst dispersed in an acetic acid solution; introducing the emulsion into a reactor at conditions suitable for the production of ketene; and reacting at least some ketene with acetic acid to produce acetic anhydride.
Abstract translation: 一种生产乙酸酐的方法，包括以大于约20,000s -1的剪切速率操作高剪切装置，其中所述高剪切装置由转子和定子构成; 在高剪切装置中形成具有分散在乙酸溶液中的液体催化剂的乳液; 在适于生产乙烯酮的条件下将乳液引入反应器; 并使至少一些乙烯酮与乙酸反应以产生乙酸酐。
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公开(公告)号：US20140081198A1
公开(公告)日：2014-03-20
申请号：US14085420
申请日：2013-11-20
Applicant: H R D Corporation
Inventor： Abbas HASSAN , Aziz HASSAN , Rayford G. ANTHONY
IPC: A61J3/00
CPC classification number: A61J3/00 , A61K9/0019 , A61M5/142 , B01F7/00766 , B01F7/008 , B01F13/1016
Abstract: In this disclosure, a method is described wherein the method comprises mixing a therapeutic gas or a therapeutic liquid or a combination thereof and a liquid carrier in a high shear device to produce a dispersion; and administering the produced dispersion intravenously to a patient; wherein the produced dispersion contains nanobubbles of the therapeutic gas or droplets of the therapeutic liquid with a mean diameter of less than about 1.5 μm. In this disclosure, a system is also described wherein the system comprises a therapeutic gas source or a therapeutic liquid source or a combination thereof; a liquid carrier source; a high shear device (HSD) having an inlet, an outlet, at least one rotor, and at least one stator separated by a shear gap; and a pump configured to control the flow rate and residence time of a fluid passing through the high shear device.
Abstract translation: 在本公开中，描述了一种方法，其中所述方法包括在高剪切装置中混合治疗气体或治疗液体或其组合和液体载体以产生分散体; 并将产生的分散体静脉内施用于患者; 其中所制备的分散体含有平均直径小于约1.5μm的治疗液体的治疗气体或液滴的纳米气泡。 在本公开中，还描述了一种系统，其中所述系统包括治疗气体源或治疗液体源或其组合; 液体载体源; 具有入口，出口，至少一个转子和由剪切间隔分开的至少一个定子的高剪切装置（HSD）; 以及构造成控制通过高剪切装置的流体的流速和停留时间的泵。
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Patent Agency Ranking
6.发明申请公开(公告)号：US20130251613A1
公开(公告)日：2013-09-26
申请号：US13847355
申请日：2013-03-19
Applicant: H R D CORPORATION
Inventor： Abbas HASSAN , Aziz HASSAN , Rayford G. ANTHONY , Alishah HASSAN
CPC classification number: C01B23/00 , B01F7/00766 , B01F13/1016 , B01J19/1806 , G21G5/00
Abstract: A system for converting a first substance into a second substance, the system including a mixing reactor configured to provide a reactant mixture comprising a first reactant, a second reactant, and a solvent; and a high shear device fluidly connected to the mixing reactor, wherein the high shear device comprises at least one rotor/stator set comprising a rotor and a complementarily-shaped stator symmetrically positioned about an axis of rotation and separated by a shear gap, wherein the shear gap is in the range of from about 10 microns to about 250 microns; and a motor configured for rotating the rotor about the axis of rotation, whereby energy can be transferred from the rotor to the reactants thereby inducing reactions between the first reactant and the second reactant to form a product.
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公开(公告)号：US20140353112A1
公开(公告)日：2014-12-04
申请号：US14451094
申请日：2014-08-04
Applicant: H R D Corporation
Inventor： Abbas HASSAN , Aziz HASSAN , Rayford G. ANTHONY , Gregory G. BORSINGER
IPC: C10G31/10
CPC classification number: C10G31/10 , B01F7/00766 , B01F13/1016 , C10G19/02 , C10G31/09 , C10G2300/202 , C10G2300/205 , C10G2300/308
Abstract: A method of removing sulfur from sour oil by subjecting sour oil having a first sulfur content to high shear in the presence of at least one desulfurizing agent to produce a high shear treated stream, wherein the at least one desulfurizing agent is selected from the group consisting of bases and inorganic salts, and separating both a sulfur-rich product and a sweetened oil product from the high shear-treated stream, wherein the sulfur-rich product comprises elemental sulfur and wherein the sweetened oil product has a second sulfur content that is less than the first sulfur content. A system for reducing the sulfur content of sour oil via at least one high shear device comprising at least one rotor and at least one complementarily-shaped stator, and at least one separation device configured to separate a sulfur-rich product and sweetened oil from the high shear-treated stream.
Abstract translation: 一种通过在至少一种脱硫剂的存在下使具有第一硫含量的酸油高剪切以产生高剪切处理的流来从酸性油中除去硫的方法，其中所述至少一种脱硫剂选自 的碱和无机盐，并且从高剪切处理的流中分离富含硫的产物和甜味油产物，其中所述富含硫的产物包含元素硫，并且其中所述甜化油产物具有较少的第二硫含量 比第一硫含量高。 一种用于通过至少一个包括至少一个转子和至少一个互补形状的定子的高剪切装置降低酸性油的硫含量的系统，以及至少一个分离装置，其被配置为将富硫产物和甜油从 高剪切处理流。
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公开(公告)号：US20140066852A1
公开(公告)日：2014-03-06
申请号：US14075105
申请日：2013-11-08
Applicant: H R D Corporation
Inventor： Abbas HASSAN , Aziz HASSAN , Rayford G. ANTHONY
CPC classification number: A61J3/00 , A61K9/0019 , A61M5/142 , B01F7/00766 , B01F7/008 , B01F13/1016
Abstract: In this disclosure, methods and systems for drug delivery utilizing high shear are disclosed. In an embodiment, a method comprises (1) subjecting a therapeutic fluid containing a drug to high shear; and (2) obtaining a processed therapeutic fluid, wherein the processed therapeutic fluid contains the drug in nano-size. In an embodiment, a method comprises (1) subjecting a drug carrier and a therapeutic fluid containing a drug to high shear; and (2) obtaining a processed therapeutic fluid, wherein the processed therapeutic fluid contains the drug carrier loaded with the drug. In an embodiment, a method comprises (1) applying high shear to a drug carrier and a therapeutic fluid containing a drug; (2) obtaining a processed therapeutic fluid, wherein the processed therapeutic fluid contains the drug-loaded carrier; and (3) modifying the drug-loaded carrier with a targeting moiety to obtain a modified drug-loaded carrier.
Abstract translation: 在本公开中，公开了利用高剪切的药物递送的方法和系统。 在一个实施方案中，一种方法包括（1）使含有药物的治疗流体经受高剪切; 和（2）获得加工的治疗液，其中所述经处理的治疗液含有纳米尺寸的药物。 在一个实施方案中，一种方法包括（1）使药物载体和含有药物的治疗液体经受高剪切; 和（2）获得加工的治疗流体，其中所述经处理的治疗液含有载有药物的药物载体。 在一个实施方案中，一种方法包括（1）对药物载体和含有药物的治疗液施加高剪切力; （2）获得经处理的治疗液，其中所述经处理的治疗液含有载药载体; 和（3）用靶向部分修饰载有药物的载体以获得修饰的药物载体。
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公开(公告)号：US20130142706A1
公开(公告)日：2013-06-06
申请号：US13753224
申请日：2013-01-29
Applicant: H R D Corporation
Inventor： Abbas HASSAN , Aziz HASSAN , Rayford G. ANTHONY , Gregory G. BORSINGER
IPC: B01J8/00
CPC classification number: C07C29/1518 , B01F3/04531 , B01F3/1221 , B01F7/00766 , B01F7/00791 , B01F13/1013 , B01F13/1016 , B01F2215/0036 , B01F2215/0427 , B01F2215/0481 , B01J8/008 , B01J8/222 , B01J19/1806 , B01J19/1862 , B01J2208/0053 , B01J2208/00823 , B01J2208/00876 , B01J2219/00083 , B01J2219/00159 , C01B3/38 , C01B3/40 , C01B2203/0233 , C01B2203/0244 , C01B2203/0283 , C01B2203/061 , C01B2203/062 , C01B2203/1064 , C01B2203/107 , C01B2203/1241 , C01B2203/1247 , C07C1/0405 , C07C1/041 , C07C1/0415 , C10G2/32 , C10G2/34 , C10G2/341 , C10G2/342 , C10G2/344 , C10G2/35 , C10G2300/1014 , C10G2300/1025 , C10G2300/1033 , C10G2300/107 , C10G2300/1077 , C10G2300/42 , C10J3/00 , C10J3/466 , C10J2300/0906 , C10J2300/0916 , C10J2300/0926 , C10J2300/093 , C10J2300/0943 , C10J2300/0956 , C10J2300/0959 , C10J2300/0976 , C10J2300/0986 , C10J2300/0989 , C10J2300/1656 , C10J2300/1659 , C10J2300/1665 , Y02P20/582 , Y02P30/20
Abstract: Herein disclosed is a system for producing an organic, the system including at least one high shear mixing device having at least one rotor and at least one stator separated by a shear gap, wherein the shear gap is the minimum distance between the at least one rotor and the at least one stator; a pump configured for delivering a fluid stream comprising liquid medium and light gas to the at least one high shear mixing device, wherein the at least one high shear mixing device is configured to form a dispersion of the light gas in the liquid medium; and a reactor comprising at least one inlet and at least one outlet, wherein the at least one inlet of the reactor is fluidly connected to the at least one high shear mixing device, and wherein the at least one outlet is configured for extracting the organic therefrom.
Abstract translation: 本文公开了一种用于生产有机物的系统，该系统包括至少一个具有至少一个转子和至少一个由剪切间隙隔开的定子的高剪切混合装置，其中剪切间隙是至少一个转子 和所述至少一个定子; 构造成用于将包含液体介质和轻质气体的流体流输送到所述至少一个高剪切混合装置的泵，其中所述至少一个高剪切混合装置构造成形成所述轻质气体在所述液体介质中的分散体; 以及包括至少一个入口和至少一个出口的反应器，其中所述反应器的所述至少一个入口流体连接到所述至少一个高剪切混合装置，并且其中所述至少一个出口构造成用于从其中提取所述有机物 。
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公开(公告)号：US20140209508A1
公开(公告)日：2014-07-31
申请号：US13790697
申请日：2013-03-08
Applicant: H R D CORPORATION
Inventor： Abbas HASSAN , Aziz HASSAN , Rayford G. ANTHONY , Gregory G. BORSINGER
CPC classification number: C10G11/20 , C10G9/00 , C10G9/36 , C10G47/00 , C10G47/32 , C10G49/007 , Y10T137/0318
Abstract: Herein disclosed is a method for thermal cracking or steam cracking of hydrocarbons comprising: supersaturating a hydrocarbonaceous liquid or slurry stream in a high shear device with a gas stream comprising steam or hydrogen and optionally one or more C1-C6 hydrocarbons to form a supersaturated dispersion; and introducing the supersaturated dispersion into a thermal cracking or steam cracking reactor to generate a product stream. In some embodiments, the method further comprises contacting the supersaturated dispersion with a cracking catalyst in a slurry, a fluidized catalyst bed, or a fixed catalyst bed. In some embodiments, the cracking catalyst is mixed with the hydrocarbonaceous liquid or slurry stream and the gas stream in the high shear device. Herein also disclosed is a system for thermal cracking or steam cracking of hydrocarbons.
Abstract translation: 本文公开了一种用于烃的热裂化或蒸汽裂化的方法，其包括：在高剪切装置中用含有蒸汽或氢气的气流和任选的一种或多种C 1 -C 6烃过饱和含烃液体或浆料流以形成过饱和分散体; 并将过饱和分散体引入热裂解或蒸汽裂解反应器中以产生产物流。 在一些实施方案中，该方法还包括使过饱和分散体与浆料，流化催化剂床或固定催化剂床中的裂化催化剂接触。 在一些实施方案中，裂化催化剂与烃类液体或浆料流以及高剪切装置中的气流混合。 本文还公开了一种用于烃的热裂解或蒸汽裂化的系统。
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