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公开(公告)号:US10221453B2
公开(公告)日:2019-03-05
申请号:US15889035
申请日:2018-02-05
Applicant: Becton, Dickinson and Company
Inventor: Song Shi , Richard L. Moore , James Garrett
IPC: G01N33/74 , G01N33/92 , C12Q1/6881
Abstract: The present invention relates to methods, monitors and systems, useful, for example, for advanced detection of sepsis in a subject.
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公开(公告)号:US20210087632A1
公开(公告)日:2021-03-25
申请号:US16596481
申请日:2019-10-08
Applicant: Becton, Dickinson and Company
Inventor: James A. Garrett , Sha-Sha Wang , Keith Thornton , Richard L. Moore , William Keating , William A. Nussbaumer , Craig C. Whiteford
IPC: C12Q1/6883 , G01N33/68 , G01N33/569 , C12Q1/6888
Abstract: Methods for predicting the development of sepsis in a subject at risk for developing sepsis are provided. In one method, features in a biomarker profile of the subject are evaluated. The subject is likely to develop sepsis if these features satisfy a particular value set. Methods for predicting the development of a stage of sepsis in a subject at risk for developing a stage of sepsis are provided. In one method, a plurality of features in a biomarker profile of the subject is evaluated. The subject is likely to have the stage of sepsis if these feature values satisfy a particular value set. Methods of diagnosing sepsis in a subject are provided. In one such method, a plurality of features in a biomarker profile of the subject is evaluated. The subject is likely to develop sepsis when the plurality of features satisfies a particular value set.
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公开(公告)号:US10443099B2
公开(公告)日:2019-10-15
申请号:US14850933
申请日:2015-09-10
Applicant: Becton, Dickinson and Company
Inventor: James A. Garrett , Sha-Sha Wang , Keith Thornton , Richard L. Moore , William Keating , William A. Nussbaumer , Craig C. Whiteford
IPC: C12Q1/68 , C12P19/34 , C12Q1/6883 , G01N33/569 , G01N33/68 , C12Q1/6888
Abstract: Methods for predicting the development of sepsis in a subject at risk for developing sepsis are provided. In one method, features in a biomarker profile of the subject are evaluated. The subject is likely to develop sepsis if these features satisfy a particular value set. Methods for predicting the development of a stage of sepsis in a subject at risk for developing a stage of sepsis are provided. In one method, a plurality of features in a biomarker profile of the subject is evaluated. The subject is likely to have the stage of sepsis if these feature values satisfy a particular value set. Methods of diagnosing sepsis in a subject are provided. In one such method, a plurality of features in a biomarker profile of the subject is evaluated. The subject is likely to develop sepsis when the plurality of features satisfies a particular value set.
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公开(公告)号:US09885084B2
公开(公告)日:2018-02-06
申请号:US15649098
申请日:2017-07-13
Applicant: Becton, Dickinson and Company
Inventor: Song Shi , Richard L. Moore , James Garrett
CPC classification number: C12Q1/6881 , C12Q2600/158 , G01N33/74 , G01N33/92 , G01N2333/90209 , G01N2333/91051 , G01N2800/26
Abstract: The present invention relates to methods, monitors and systems, useful, for example, for advanced detection of sepsis in a subject.
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公开(公告)号:US20160168638A1
公开(公告)日:2016-06-16
申请号:US14850933
申请日:2015-09-10
Applicant: Becton, Dickinson and Company
Inventor: James A. Garrett , Sha-Sha Wang , Keith Thornton , Richard L. Moore , William Keating , William A. Nussbaumer , Craig C. Whiteford
CPC classification number: C12Q1/6883 , C12Q1/6888 , C12Q2600/112 , C12Q2600/158 , C12Q2600/16 , G01N33/56911 , G01N33/6893 , G01N2333/5412 , G01N2333/5421 , G01N2800/26 , G01N2800/50
Abstract: Methods for predicting the development of sepsis in a subject at risk for developing sepsis are provided. In one method, features in a biomarker profile of the subject are evaluated. The subject is likely to develop sepsis if these features satisfy a particular value set. Methods for predicting the development of a stage of sepsis in a subject at risk for developing a stage of sepsis are provided. In one method, a plurality of features in a biomarker profile of the subject is evaluated. The subject is likely to have the stage of sepsis if these feature values satisfy a particular value set. Methods of diagnosing sepsis in a subject are provided. In one such method, a plurality of features in a biomarker profile of the subject is evaluated. The subject is likely to develop sepsis when the plurality of features satisfies a particular value set.
Abstract translation: 提供了预防脓毒症风险发生的患者脓毒症发展的方法。 在一种方法中,评估受试者的生物标志物特征中的特征。 如果这些特征满足特定的值集合,主体可能会发展为败血症。 提供了预防脓毒症发展阶段脓毒症发展阶段发展的方法。 在一种方法中,评估受试者的生物标志物轮廓中的多个特征。 如果这些特征值满足特定的值集合,受试者可能具有脓毒症的阶段。 提供诊断受试者败血症的方法。 在一种这样的方法中,评估对象的生物标志物轮廓中的多个特征。 当多个特征满足特定值集合时,受试者可能发展为败血症。
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公开(公告)号:US20240060132A1
公开(公告)日:2024-02-22
申请号:US18168517
申请日:2023-02-13
Applicant: Becton, Dickinson and Company
Inventor: James A. Garrett , Sha-Sha Wang , Keith Thornton , Richard L. Moore , William Keating , William A. Nussbaumer , Craig C. Whiteford
IPC: C12Q1/6883 , G01N33/68 , G01N33/569 , C12Q1/6888
CPC classification number: C12Q1/6883 , G01N33/6893 , G01N33/56911 , C12Q1/6888 , G01N2800/26 , C12Q2600/112 , C12Q2600/158 , C12Q2600/16 , G01N2333/5412 , G01N2333/5421 , G01N2800/50
Abstract: Methods for predicting the development of sepsis in a subject at risk for developing sepsis are provided. In one method, features in a biomarker profile of the subject are evaluated. The subject is likely to develop sepsis if these features satisfy a particular value set. Methods for predicting the development of a stage of sepsis in a subject at risk for developing a stage of sepsis are provided. In one method, a plurality of features in a biomarker profile of the subject is evaluated. The subject is likely to have the stage of sepsis if these feature values satisfy a particular value set. Methods of diagnosing sepsis in a subject are provided. In one such method, a plurality of features in a biomarker profile of the subject is evaluated. The subject is likely to develop sepsis when the plurality of features satisfies a particular value set.
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公开(公告)号:US20180305758A1
公开(公告)日:2018-10-25
申请号:US15889035
申请日:2018-02-05
Applicant: Becton, Dickinson and Company
Inventor: Song Shi , Richard L. Moore , James Garrett
IPC: C12Q1/6881 , G01N33/74 , G01N33/92
CPC classification number: C12Q1/6881 , C12Q2600/158 , G01N33/74 , G01N33/92 , G01N2333/90209 , G01N2333/91051 , G01N2800/26
Abstract: The present invention relates to methods, monitors and systems, useful, for example, for advanced detection of sepsis in a subject.
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公开(公告)号:US20220074831A1
公开(公告)日:2022-03-10
申请号:US17424396
申请日:2020-01-23
Applicant: BECTON DICKINSON AND COMPANY
Inventor: Qihua Xu , Kristin Weidemaier , Jon E. Salomon , Alexander G. Lastovich , Eric A. Fallows , Sean Connell , Joshua Herr , Meghan Wolfgang , Michael A. Brasch , Richard L. Moore , David S. Sebba , Cristian Clavijo , Shirley Ng , Richard Abbott , Alexander Adam Papp , Henry Li-Wei Fu , Caitlin Marie Austin , Sean Patrick Dowling , Owen Lewis Joyce , Michael L. Kiplinger , William Kevin Carpenter
Abstract: Methods and apparatus provide filtration for concentrating analytes, such as bacteria or exosomes, of a biological sample, such as blood or urine. The technology may employ membrane devices that implement one or more tangential flow filtration processes such as in stages. An example membrane device may typically include a membrane having sides and ends. The membrane may selectively permit constituent(s) of the sample to pass through while retaining other constituents at one side. An input chamber of the device may include an inlet near one end and an outlet near the other end, and that may permit a tangential flow of the sample along the first side surface, and a trans-membrane passing of constituent(s). An output chamber of the device may be configured at the second side surface to receive the passing constituents. Such devices may be provided in a kit to facilitate targeting of a desired biological analyte concentration.
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公开(公告)号:US20180002752A1
公开(公告)日:2018-01-04
申请号:US15649098
申请日:2017-07-13
Applicant: Becton, Dickinson and Company
Inventor: Song Shi , Richard L. Moore , James Garrett
CPC classification number: C12Q1/6881 , C12Q2600/158 , G01N33/74 , G01N33/92 , G01N2333/90209 , G01N2333/91051 , G01N2800/26
Abstract: The present invention relates to methods, monitors and systems, useful, for example, for advanced detection of sepsis in a subject.
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公开(公告)号:US09708661B2
公开(公告)日:2017-07-18
申请号:US14743735
申请日:2015-06-18
Applicant: Becton, Dickinson and Company
Inventor: Song Shi , Richard L. Moore , James Garrett
CPC classification number: C12Q1/6881 , C12Q2600/158 , G01N33/74 , G01N33/92 , G01N2333/90209 , G01N2333/91051 , G01N2800/26
Abstract: The present invention relates to methods, monitors and systems, useful, for example, for advanced detection of sepsis in a subject.
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