-
公开(公告)号：US10549242B2
公开(公告)日：2020-02-04
申请号：US15565326
申请日：2016-06-07
Applicant: Becton, Dickinson and Company
Inventor： Qihua Xu , Alexander G. Lastovich
Abstract: A filtration cell (10) for a biological sample having an outer housing (12) defining a first chamber and an inner housing (14) defining a second chamber is disclosed. The inner housing is disposed within the first chamber and rotatable with respect to the outer housing and at least a portion of the inner housing includes a filtration membrane (52). Upon rotation of the inner housing, a first portion of the biological sample passes from the first chamber into the second chamber and a second portion of the biological sample is restrained in the first chamber. Alternatively, the filtration cell may also include a rotation element disposed in the inner housing. Upon rotation of the rotation element with respect to the inner housing, a first portion of the biological sample to passes from the second chamber into the first chamber and a second portion of the biological sample is restrained in the second chamber.
-
公开(公告)号：US20180059118A1
公开(公告)日：2018-03-01
申请号：US15712972
申请日：2017-09-22
Applicant: BECTON DICKINSON AND COMPANY
Inventor： Kristin Weidemaier , Christian Sandmann , William Shannon Dillmore , James L. Schram , W. William Stewart , Robert E. Pearson , Helen Hsieh , Steven Keith , Rajendra R. Bhat , Andrea Liebmann-Vinson , Adam Craig Curry , Alexander G. Lastovich
IPC: G01N33/58 , G01N21/65 , G01N33/543
CPC classification number: G01N33/587 , G01N21/658 , G01N33/54333
Abstract: Disclosed herein are diagnostic assays using surface enhanced Raman spectroscopy (SERS)-active particles, including liquid-based assays; magnetic capture assays; microparticle-nanoparticle satellite structures for signal amplification in an assay; composite SERS-active particles useful for enhanced detection of targets; and sample tubes and processes for using the same.
-
公开(公告)号：US11016095B2
公开(公告)日：2021-05-25
申请号：US15712972
申请日：2017-09-22
Applicant: BECTON DICKINSON AND COMPANY
Inventor： Kristin Weidemaier , Christian Sandmann , William Shannon Dillmore , James L. Schram , W. William Stewart , Robert E. Pearson , Helen Hsieh , Steven Keith , Rajendra R. Bhat , Andrea Liebmann-Vinson , Adam Craig Curry , Alexander G. Lastovich
IPC: G01N33/58 , G01N21/65 , G01N33/543
Abstract: Disclosed herein are diagnostic assays using surface enhanced Raman spectroscopy (SERS)-active particles, including liquid-based assays; magnetic capture assays; microparticle-nanoparticle satellite structures for signal amplification in an assay; composite SERS-active particles useful for enhanced detection of targets; and sample tubes and processes for using the same.
-
公开(公告)号：US10996146B2
公开(公告)日：2021-05-04
申请号：US15978026
申请日：2018-05-11
Applicant: BECTON, DICKINSON AND COMPANY
Inventor： Richard Abbott , Alexander G. Lastovich , Friedrich G. Hahn , Jacob Jones
Abstract: Tissue dissociators configured to disrupt a biological tissue sample are provided. Aspects of the tissue dissociators according to certain embodiments include a blade holder having a blade and a sample holder that includes a tissue actuator having a distal end pliable stopper where the tissue actuator is configured to be displaced along a longitudinal axis with the sample holder. Also provided are methods of dissociating a biological tissue sample with the tissue dissociators, as well as kits including the tissue dissociators.
-
公开(公告)号：US20220074831A1
公开(公告)日：2022-03-10
申请号：US17424396
申请日：2020-01-23
Applicant: BECTON DICKINSON AND COMPANY
Inventor： Qihua Xu , Kristin Weidemaier , Jon E. Salomon , Alexander G. Lastovich , Eric A. Fallows , Sean Connell , Joshua Herr , Meghan Wolfgang , Michael A. Brasch , Richard L. Moore , David S. Sebba , Cristian Clavijo , Shirley Ng , Richard Abbott , Alexander Adam Papp , Henry Li-Wei Fu , Caitlin Marie Austin , Sean Patrick Dowling , Owen Lewis Joyce , Michael L. Kiplinger , William Kevin Carpenter
Abstract: Methods and apparatus provide filtration for concentrating analytes, such as bacteria or exosomes, of a biological sample, such as blood or urine. The technology may employ membrane devices that implement one or more tangential flow filtration processes such as in stages. An example membrane device may typically include a membrane having sides and ends. The membrane may selectively permit constituent(s) of the sample to pass through while retaining other constituents at one side. An input chamber of the device may include an inlet near one end and an outlet near the other end, and that may permit a tangential flow of the sample along the first side surface, and a trans-membrane passing of constituent(s). An output chamber of the device may be configured at the second side surface to receive the passing constituents. Such devices may be provided in a kit to facilitate targeting of a desired biological analyte concentration.
-
Patent Agency Ranking
公开(公告)号：US20180071689A1
公开(公告)日：2018-03-15
申请号：US15565307
申请日：2016-06-07
Applicant: Becton, Dickinson and Company
Inventor： Qihua Xu , Alexander G. Lastovich
CPC classification number: B01D67/0032 , A61M1/1621 , A61M1/1631 , A61M1/3496 , A61M1/3643 , A61M1/3644 , A61M1/365 , A61M2202/0415 , B01D61/147 , B01D61/18 , B01D63/087 , B01D71/50 , B01D2321/2066 , B01D2321/2083 , B01D2323/04 , B01D2325/38
Abstract: A filtration cell (10) for a biological sample including an upper chamber for receiving the biological sample to be filtered, a lower chamber in fluid communication with the upper chamber, and a filtration membrane (14) positioned between the upper chamber and the lower chamber is disclosed. A surface of the filtration membrane has a contact angle >90°. The flow of the biological sample through the upper chamber may be tangential to the filtration membrane and a filtrate passing through the filtration membrane may be collected in the lower chamber. Also, a method of filtering a biological sample including passing the biological sample through an upper chamber of a filtration cell as described above and collecting a filtrate in the lower chamber is disclosed.
-
公开(公告)号：US20210378567A1
公开(公告)日：2021-12-09
申请号：US17340788
申请日：2021-06-07
Applicant: BECTON DICKINSON AND COMPANY
Inventor： Kristin Weidemaier , Alexander G. Lastovich , Qihua Xu , Richard Abbott
Abstract: A blood separation device that allows high quality plasma to be generated using a single power source. The device includes a housing with an inlet port adapted to receive the blood sample, a first chamber having a first chamber flow channel in fluid communication with the inlet port, a second chamber having a second chamber flow channel, a separation member disposed between the first chamber and the second chamber. In some embodiments, the blood separation device detects or tests for the presence of a substance, such as an antigen or an antibody.
-
公开(公告)号：US20180348097A1
公开(公告)日：2018-12-06
申请号：US15978026
申请日：2018-05-11
Applicant: BECTON, DICKINSON AND COMPANY
Inventor： Richard Abbott , Alexander G. Lastovich , Friedrich G. Hahn , Jacob Jones
Abstract: Tissue dissociators configured to disrupt a biological tissue sample are provided. Aspects of the tissue dissociators according to certain embodiments include a blade holder having a blade and a sample holder that includes a tissue actuator having a distal end pliable stopper where the tissue actuator is configured to be displaced along a longitudinal axis with the sample holder. Also provided are methods of dissociating a biological tissue sample with the tissue dissociators, as well as kits including the tissue dissociators.
-
公开(公告)号：US20180056243A1
公开(公告)日：2018-03-01
申请号：US15565326
申请日：2016-06-07
Applicant: Becton, Dickinson and Company
Inventor： Qihua Xu , Alexander G. Lastovich
CPC classification number: B01D63/16 , A61M1/262 , A61M1/3496 , B01D61/147 , B01D61/18 , B01D63/062 , B01D69/02 , B01D71/50 , B01D2313/04 , B01D2315/02 , B01D2315/04 , B01D2325/04 , B01D2325/06
Abstract: A filtration cell (10) for a biological sample having an outer housing (12) defining a first chamber and an inner housing (14) defining a second chamber is disclosed. The inner housing is disposed within the first chamber and rotatable with respect to the outer housing and at least a portion of the inner housing includes a filtration membrane (52). Upon rotation of the inner housing, a first portion of the biological sample passes from the first chamber into the second chamber and a second portion of the biological sample is restrained in the first chamber. Alternatively, the filtration cell may also include a rotation element disposed in the inner housing. Upon rotation of the rotation element with respect to the inner housing, a first portion of the biological sample to passes from the second chamber into the first chamber and a second portion of the biological sample is restrained in the second chamber.
-
公开(公告)号：US20240377333A1
公开(公告)日：2024-11-14
申请号：US18316148
申请日：2023-05-11
Applicant: Becton, Dickinson and Company
Inventor： Melody Mei Hee Kuroda , Joseph Thomas , David Sebba , Alexander G. Lastovich
Abstract: Methods, kits and devices for detecting noble metal-containing compound contamination of a surface are provided according to aspects of the present disclosure. According to aspects of the invention, methods for detecting noble metal-containing compound contamination of a surface include collecting a sample comprising a noble metal-containing compound from said surface; contacting said sample with a dye and a reducing agent to form a test solution; and measuring an absorbance of the test solution.
-
-
-
-
-
-
-
-
-
Search Results
12
records
(took 0.017 seconds)
