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公开(公告)号：US10996146B2
公开(公告)日：2021-05-04
申请号：US15978026
申请日：2018-05-11
Applicant: BECTON, DICKINSON AND COMPANY
Inventor： Richard Abbott , Alexander G. Lastovich , Friedrich G. Hahn , Jacob Jones
Abstract: Tissue dissociators configured to disrupt a biological tissue sample are provided. Aspects of the tissue dissociators according to certain embodiments include a blade holder having a blade and a sample holder that includes a tissue actuator having a distal end pliable stopper where the tissue actuator is configured to be displaced along a longitudinal axis with the sample holder. Also provided are methods of dissociating a biological tissue sample with the tissue dissociators, as well as kits including the tissue dissociators.
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公开(公告)号：US20210378567A1
公开(公告)日：2021-12-09
申请号：US17340788
申请日：2021-06-07
Applicant: BECTON DICKINSON AND COMPANY
Inventor： Kristin Weidemaier , Alexander G. Lastovich , Qihua Xu , Richard Abbott
Abstract: A blood separation device that allows high quality plasma to be generated using a single power source. The device includes a housing with an inlet port adapted to receive the blood sample, a first chamber having a first chamber flow channel in fluid communication with the inlet port, a second chamber having a second chamber flow channel, a separation member disposed between the first chamber and the second chamber. In some embodiments, the blood separation device detects or tests for the presence of a substance, such as an antigen or an antibody.
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公开(公告)号：US20180348097A1
公开(公告)日：2018-12-06
申请号：US15978026
申请日：2018-05-11
Applicant: BECTON, DICKINSON AND COMPANY
Inventor： Richard Abbott , Alexander G. Lastovich , Friedrich G. Hahn , Jacob Jones
Abstract: Tissue dissociators configured to disrupt a biological tissue sample are provided. Aspects of the tissue dissociators according to certain embodiments include a blade holder having a blade and a sample holder that includes a tissue actuator having a distal end pliable stopper where the tissue actuator is configured to be displaced along a longitudinal axis with the sample holder. Also provided are methods of dissociating a biological tissue sample with the tissue dissociators, as well as kits including the tissue dissociators.
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公开(公告)号：US20220074831A1
公开(公告)日：2022-03-10
申请号：US17424396
申请日：2020-01-23
Applicant: BECTON DICKINSON AND COMPANY
Inventor： Qihua Xu , Kristin Weidemaier , Jon E. Salomon , Alexander G. Lastovich , Eric A. Fallows , Sean Connell , Joshua Herr , Meghan Wolfgang , Michael A. Brasch , Richard L. Moore , David S. Sebba , Cristian Clavijo , Shirley Ng , Richard Abbott , Alexander Adam Papp , Henry Li-Wei Fu , Caitlin Marie Austin , Sean Patrick Dowling , Owen Lewis Joyce , Michael L. Kiplinger , William Kevin Carpenter
Abstract: Methods and apparatus provide filtration for concentrating analytes, such as bacteria or exosomes, of a biological sample, such as blood or urine. The technology may employ membrane devices that implement one or more tangential flow filtration processes such as in stages. An example membrane device may typically include a membrane having sides and ends. The membrane may selectively permit constituent(s) of the sample to pass through while retaining other constituents at one side. An input chamber of the device may include an inlet near one end and an outlet near the other end, and that may permit a tangential flow of the sample along the first side surface, and a trans-membrane passing of constituent(s). An output chamber of the device may be configured at the second side surface to receive the passing constituents. Such devices may be provided in a kit to facilitate targeting of a desired biological analyte concentration.
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