公开(公告)号：US20240060132A1

公开(公告)日：2024-02-22

申请号：US18168517

申请日：2023-02-13

Applicant: Becton, Dickinson and Company

Inventor： James A. Garrett ,  Sha-Sha Wang ,  Keith Thornton ,  Richard L. Moore ,  William Keating ,  William A. Nussbaumer ,  Craig C. Whiteford

IPC: C12Q1/6883 ,  G01N33/68 ,  G01N33/569 ,  C12Q1/6888

CPC classification number: C12Q1/6883 ,  G01N33/6893 ,  G01N33/56911 ,  C12Q1/6888 ,  G01N2800/26 ,  C12Q2600/112 ,  C12Q2600/158 ,  C12Q2600/16 ,  G01N2333/5412 ,  G01N2333/5421 ,  G01N2800/50

Abstract: Methods for predicting the development of sepsis in a subject at risk for developing sepsis are provided. In one method, features in a biomarker profile of the subject are evaluated. The subject is likely to develop sepsis if these features satisfy a particular value set. Methods for predicting the development of a stage of sepsis in a subject at risk for developing a stage of sepsis are provided. In one method, a plurality of features in a biomarker profile of the subject is evaluated. The subject is likely to have the stage of sepsis if these feature values satisfy a particular value set. Methods of diagnosing sepsis in a subject are provided. In one such method, a plurality of features in a biomarker profile of the subject is evaluated. The subject is likely to develop sepsis when the plurality of features satisfies a particular value set.

公开(公告)号：US11578367B2

公开(公告)日：2023-02-14

申请号：US16596481

申请日：2019-10-08

Applicant: Becton, Dickinson and Company

Inventor： James A. Garrett ,  Sha-Sha Wang ,  Keith Thornton ,  Richard L. Moore ,  William Keating ,  William A. Nussbaumer ,  Craig C. Whiteford

IPC: C12Q1/68 ,  C12P19/34 ,  C12Q1/6883 ,  G01N33/68 ,  G01N33/569 ,  C12Q1/6888

Abstract: Methods for predicting the development of sepsis in a subject at risk for developing sepsis are provided. In one method, features in a biomarker profile of the subject are evaluated. The subject is likely to develop sepsis if these features satisfy a particular value set. Methods for predicting the development of a stage of sepsis in a subject at risk for developing a stage of sepsis are provided. In one method, a plurality of features in a biomarker profile of the subject is evaluated. The subject is likely to have the stage of sepsis if these feature values satisfy a particular value set. Methods of diagnosing sepsis in a subject are provided. In one such method, a plurality of features in a biomarker profile of the subject is evaluated. The subject is likely to develop sepsis when the plurality of features satisfies a particular value set.

公开(公告)号：US20210087632A1

公开(公告)日：2021-03-25

申请号：US16596481

申请日：2019-10-08

Applicant: Becton, Dickinson and Company

Inventor： James A. Garrett ,  Sha-Sha Wang ,  Keith Thornton ,  Richard L. Moore ,  William Keating ,  William A. Nussbaumer ,  Craig C. Whiteford

IPC: C12Q1/6883 ,  G01N33/68 ,  G01N33/569 ,  C12Q1/6888

Abstract: Methods for predicting the development of sepsis in a subject at risk for developing sepsis are provided. In one method, features in a biomarker profile of the subject are evaluated. The subject is likely to develop sepsis if these features satisfy a particular value set. Methods for predicting the development of a stage of sepsis in a subject at risk for developing a stage of sepsis are provided. In one method, a plurality of features in a biomarker profile of the subject is evaluated. The subject is likely to have the stage of sepsis if these feature values satisfy a particular value set. Methods of diagnosing sepsis in a subject are provided. In one such method, a plurality of features in a biomarker profile of the subject is evaluated. The subject is likely to develop sepsis when the plurality of features satisfies a particular value set.

公开(公告)号：US10443099B2

公开(公告)日：2019-10-15

申请号：US14850933

申请日：2015-09-10

Applicant: Becton, Dickinson and Company

Inventor： James A. Garrett ,  Sha-Sha Wang ,  Keith Thornton ,  Richard L. Moore ,  William Keating ,  William A. Nussbaumer ,  Craig C. Whiteford

IPC: C12Q1/68 ,  C12P19/34 ,  C12Q1/6883 ,  G01N33/569 ,  G01N33/68 ,  C12Q1/6888

Abstract: Methods for predicting the development of sepsis in a subject at risk for developing sepsis are provided. In one method, features in a biomarker profile of the subject are evaluated. The subject is likely to develop sepsis if these features satisfy a particular value set. Methods for predicting the development of a stage of sepsis in a subject at risk for developing a stage of sepsis are provided. In one method, a plurality of features in a biomarker profile of the subject is evaluated. The subject is likely to have the stage of sepsis if these feature values satisfy a particular value set. Methods of diagnosing sepsis in a subject are provided. In one such method, a plurality of features in a biomarker profile of the subject is evaluated. The subject is likely to develop sepsis when the plurality of features satisfies a particular value set.

公开(公告)号：US20160168638A1

公开(公告)日：2016-06-16

申请号：US14850933

申请日：2015-09-10

Applicant: Becton, Dickinson and Company

Inventor： James A. Garrett ,  Sha-Sha Wang ,  Keith Thornton ,  Richard L. Moore ,  William Keating ,  William A. Nussbaumer ,  Craig C. Whiteford

IPC: C12Q1/68 ,  G01N33/68

CPC classification number: C12Q1/6883 ,  C12Q1/6888 ,  C12Q2600/112 ,  C12Q2600/158 ,  C12Q2600/16 ,  G01N33/56911 ,  G01N33/6893 ,  G01N2333/5412 ,  G01N2333/5421 ,  G01N2800/26 ,  G01N2800/50

Abstract: Methods for predicting the development of sepsis in a subject at risk for developing sepsis are provided. In one method, features in a biomarker profile of the subject are evaluated. The subject is likely to develop sepsis if these features satisfy a particular value set. Methods for predicting the development of a stage of sepsis in a subject at risk for developing a stage of sepsis are provided. In one method, a plurality of features in a biomarker profile of the subject is evaluated. The subject is likely to have the stage of sepsis if these feature values satisfy a particular value set. Methods of diagnosing sepsis in a subject are provided. In one such method, a plurality of features in a biomarker profile of the subject is evaluated. The subject is likely to develop sepsis when the plurality of features satisfies a particular value set.

Abstract translation: 提供了预防脓毒症风险发生的患者脓毒症发展的方法。 在一种方法中，评估受试者的生物标志物特征中的特征。 如果这些特征满足特定的值集合，主体可能会发展为败血症。 提供了预防脓毒症发展阶段脓毒症发展阶段发展的方法。 在一种方法中，评估受试者的生物标志物轮廓中的多个特征。 如果这些特征值满足特定的值集合，受试者可能具有脓毒症的阶段。 提供诊断受试者败血症的方法。 在一种这样的方法中，评估对象的生物标志物轮廓中的多个特征。 当多个特征满足特定值集合时，受试者可能发展为败血症。