公开(公告)号：US10123894B2

公开(公告)日：2018-11-13

申请号：US15699938

申请日：2017-09-08

Applicant: Abbott Cardiovascular Systems Inc.

Inventor： Mikael Trollsas ,  Michael H. Ngo ,  Boris Anukhin ,  Alexander Nikanorov ,  Syed Hossainy ,  John E. Papp ,  Dudley Jayasinghe ,  Zella Solter

IPC: A61F2/958 ,  B21D39/04 ,  A61F2/91 ,  A61L27/00 ,  A61L31/06 ,  A61F2/86 ,  A61F2/844 ,  B29C35/08 ,  A61L31/14 ,  A61F2/89 ,  A61F2/82 ,  A61F2/915 ,  A61F2/95 ,  B29K67/00 ,  B29L23/00 ,  B29L31/00

Abstract: A method of crimping a stent is disclosed. The stent includes a minimum crimped diameter such that in the minimum crimped diameter, a pair of stent rings, between which marker support structures reside, do not make contact with the marker support structures. The crimped profile of the stent of the present invention can be as small as the crimped profile of a same stent but without the maker support structures.

公开(公告)号：US09907685B2

公开(公告)日：2018-03-06

申请号：US14050283

申请日：2013-10-09

Applicant: Abbott Cardiovascular Systems Inc.

Inventor： Mikael Trollsas ,  Michael H. Ngo ,  Boris Anukhin ,  Syed Hossainy

IPC: A61F2/82 ,  A61F2/958 ,  A61F2/91 ,  A61L27/00 ,  A61L31/06 ,  A61F2/86 ,  A61F2/844 ,  B29C35/08 ,  A61L31/14 ,  A61F2/89 ,  A61F2/915 ,  A61F2/95 ,  B29K67/00 ,  B29L23/00 ,  B29L31/00

CPC classification number: A61F2/958 ,  A61F2/82 ,  A61F2/844 ,  A61F2/86 ,  A61F2/89 ,  A61F2/91 ,  A61F2/915 ,  A61F2002/825 ,  A61F2002/91558 ,  A61F2002/91566 ,  A61F2002/91575 ,  A61F2002/9522 ,  A61F2210/0004 ,  A61F2210/0014 ,  A61F2210/0019 ,  A61F2210/0076 ,  A61F2230/0006 ,  A61F2230/0008 ,  A61F2250/0067 ,  A61F2250/0096 ,  A61F2250/0098 ,  A61L27/00 ,  A61L31/06 ,  A61L31/14 ,  B21D39/046 ,  B29C35/08 ,  B29C2035/0838 ,  B29K2067/046 ,  B29L2023/00 ,  B29L2031/7543 ,  Y10T29/49826 ,  Y10T29/4987 ,  Y10T29/49908 ,  Y10T29/49925 ,  Y10T29/49927 ,  C08L67/04 ,  C08L71/02

Abstract: A medical device includes a polymer scaffold crimped to a catheter having an expansion balloon. The scaffold, after being deployed by the balloon, provides a crush recovery of about 90% after the diameter of the scaffold has been pinched or crushed by 50%. The scaffold has a pattern including an asymmetric closed cell connecting links connecting the closed cells.

公开(公告)号：US09827119B2

公开(公告)日：2017-11-28

申请号：US14323992

申请日：2014-07-03

Applicant: Abbott Cardiovascular Systems Inc.

Inventor： Boris Anukhin ,  Michael H. Ngo ,  Mikael Trollsas ,  Syed Hossainy ,  John Papp

IPC: A61F17/00 ,  A61F2/89 ,  A61F2/82 ,  B29C69/00 ,  B29C55/24 ,  A61F2/915 ,  A61M25/10 ,  B23P11/00

CPC classification number: A61F2/89 ,  A61F2/82 ,  A61F2/915 ,  A61F2002/91508 ,  A61F2002/91575 ,  A61F2240/002 ,  A61M25/1034 ,  B23P11/005 ,  B29C55/24 ,  B29C69/00 ,  Y10T29/49908

Abstract: A medical device includes a polymer scaffold crimped to a catheter having an expansion balloon. The scaffold, after being deployed by the balloon, provides a crush recovery of about 90% after the diameter of the scaffold has been pinched or crushed by 50%. The scaffold also has a reduced crimped profile and a modification of the scaffold's ring structure at the crowns that contributes to the reduced crimped profile.

公开(公告)号：US09694112B2

公开(公告)日：2017-07-04

申请号：US14965387

申请日：2015-12-10

Applicant: ABBOTT CARDIOVASCULAR SYSTEMS INC.

Inventor： John Stankus ,  Mikael Trollsas ,  Syed Hossainy

IPC: A61F2/00 ,  A61L29/08 ,  A61L31/16 ,  A61M25/10 ,  A61L31/10 ,  A61L29/14 ,  A61L29/16 ,  A61F2/82

CPC classification number: A61L29/085 ,  A61F2/82 ,  A61F2250/0067 ,  A61L29/146 ,  A61L29/16 ,  A61L31/10 ,  A61L31/16 ,  A61M25/10 ,  A61M25/1006 ,  A61M2025/1013 ,  A61M2025/105 ,  A61M2025/1075

Abstract: The present invention relates to systems for and corresponding methods of delivering a therapeutic agent to a vessel wall of a body lumen by providing a compound capable of being crosslinked after intraluminal release onto a vessel wall so that the therapeutic agent is temporarily retained at the site of delivery by the crosslinked compound.

公开(公告)号：US20170027724A1

公开(公告)日：2017-02-02

申请号：US15290886

申请日：2016-10-11

Applicant: Abbott Cardiovascular Systems Inc.

Inventor： Syed Hossainy ,  Paul Consigny ,  Dariush Davalian ,  James Su ,  Michael Ngo ,  Adrain Gale ,  Jesus Magana ,  Mikael Trollsas ,  Evan Norton ,  Benjamyn Serna

IPC: A61F2/958 ,  A61M29/02 ,  A61F2/915 ,  A61F11/00 ,  A61B1/06

CPC classification number: A61F2/958 ,  A61B1/06 ,  A61F2/915 ,  A61F11/002 ,  A61F2002/91575 ,  A61F2002/91583 ,  A61F2230/0067 ,  A61F2250/0018 ,  A61F2250/0026 ,  A61F2250/0046 ,  A61F2250/0048 ,  A61F2250/005 ,  A61F2250/0082 ,  A61M25/10 ,  A61M29/02 ,  A61M2025/105 ,  A61M2025/1059 ,  A61M2210/0675

Abstract: A polymeric stent can be implanted for treatment of the Eustachian tube. The stent can be designed to have length-dependent radial strength to allow it to stay within the Eustachian tube and to allow normal closing and opening of the Eustachian tube. A balloon can be used to implant the stent, and the balloon can be coated with a therapeutic agent. A coated balloon can also be used to transfer therapeutic agents to the sinus cavity during a balloon sinus dilation procedure.

Abstract translation: 可以植入聚合物支架以治疗咽鼓管。 支架可以设计成具有长度依赖的径向强度，以允许其保持在咽鼓管内并允许正常的关闭和打开咽鼓管。 可以使用气囊来植入支架，并且可以用治疗剂涂覆气囊。 在气球窦扩张过程中，涂覆的气囊也可以用于将治疗剂转移到窦腔。

公开(公告)号：US20160175493A1

公开(公告)日：2016-06-23

申请号：US14931041

申请日：2015-11-03

Applicant: Abbott Cardiovascular Systems Inc.

Inventor： Mikael Trollsas ,  John Stankus ,  Michael N. Ngo ,  Wen Chung Tsai ,  Thierry Glauser

IPC: A61L31/14 ,  A61L31/08 ,  A61L31/06 ,  B05D5/00

CPC classification number: A61L31/148 ,  A61L31/06 ,  A61L31/08 ,  A61L31/141 ,  A61L2420/02 ,  B05D5/00 ,  C08L67/04

Abstract: Methods of fabricating a bioresorbable polymer scaffold are disclosed including a step of inducing crystallization in a bioresorbable polymer construct through exposure to a liquid penetrant.

Abstract translation: 公开了制备生物可再吸收的聚合物支架的方法，包括通过暴露于液体渗透剂在生物可再吸收的聚合物构造体中诱导结晶的步骤。

公开(公告)号：US09090745B2

公开(公告)日：2015-07-28

申请号：US14081287

申请日：2013-11-15

Applicant: Abbott Cardiovascular Systems Inc.

Inventor： Stephen D. Pacetti ,  Mikael Trollsas

IPC: A61F2/00 ,  A61F13/00 ,  A61K38/00 ,  A61F2/04 ,  C08G81/00 ,  A61L29/04 ,  A61L29/16 ,  A61L31/04 ,  A61L31/16 ,  A61K31/436 ,  A61L31/06

CPC classification number: A61L31/10 ,  A61K31/436 ,  A61L29/041 ,  A61L29/16 ,  A61L31/048 ,  A61L31/06 ,  A61L31/16 ,  A61L2300/606 ,  A61L2420/00 ,  C08G81/00

Abstract: The present invention is directed to polymeric materials made of biodegradable, bioabsorbable triblock copolymers and implantable devices (e.g., drug-delivery stents) containing such polymeric materials. The polymeric materials may also contain at least one therapeutic substance. The polymeric materials are formulated so as to improve the mechanical and adhesion properties, degradation, biocompatibility and drug permeability of such materials and, thus, implantable devices formed of such materials.

公开(公告)号：US20150151030A1

公开(公告)日：2015-06-04

申请号：US14605666

申请日：2015-01-26

Applicant: Abbott Cardiovascular Systems Inc.

Inventor： Lothar W. Kleiner ,  John Stankus ,  Nam D. Pham ,  Michael H. Ngo ,  Bozena Zofia Maslanka ,  Syed Faiyaz Ahmed Hossainy ,  Mikael Trollsas ,  Yiwen Tang

IPC: A61L31/16 ,  A61L31/14 ,  A61L31/10 ,  A61K31/436 ,  A61K47/34

CPC classification number: A61L31/16 ,  A61K31/436 ,  A61K47/34 ,  A61L31/10 ,  A61L31/148 ,  A61L2300/416 ,  C08L67/04

Abstract: The present invention relates to implantable medical devices coated with polymer having tunable hydrophobicity and their use in the treatment of vascular diseases.

Abstract translation: 本发明涉及涂覆有具有可调谐疏水性的聚合物的可植入医疗装置及其在治疗血管疾病中的用途。

公开(公告)号：US20150142099A1

公开(公告)日：2015-05-21

申请号：US14603087

申请日：2015-01-22

Applicant: Abbott Cardiovascular Systems Inc.

Inventor： John S. Stankus ,  Hugh Zhao ,  Mikael Trollsas ,  Syed Faiyaz Ahmed Hossainy ,  Michael H. Ngo ,  Yunbing Wang ,  Benny Serna

IPC: A61F2/86

CPC classification number: A61F2/86 ,  A61F2/915 ,  A61F2002/91508 ,  A61F2002/91541 ,  A61F2002/91558 ,  A61F2210/0019 ,  A61F2230/0054 ,  A61F2230/0056 ,  A61F2230/006 ,  A61F2250/001 ,  A61L31/041 ,  A61L31/06 ,  A61L31/14 ,  A61L31/148 ,  A61L31/16 ,  A61L2400/16 ,  C08L67/04

Abstract: Bioabsorbable scaffolds having high crush recoverability, high fracture resistance, and reduced or no recoil due to self expanding properties at physiological conditions are disclosed. The scaffolds are made from a random copolymer of PLLA and a rubbery polymer such as polycaprolactone.

Abstract translation: 公开了具有高压碎可恢复性，高抗断裂性和由于在生理条件下的自膨胀性能而减少或无反冲的生物可吸收支架。 支架由PLLA和橡胶状聚合物如聚己内酯的无规共聚物制成。

公开(公告)号：US20140330361A1

公开(公告)日：2014-11-06

申请号：US14333354

申请日：2014-07-16

Applicant: Abbott Cardiovascular Systems Inc.

Inventor： John E. Papp ,  Syed Faiyaz Ahmed Hossainy ,  Michael Ngo ,  Chad Abunassar ,  Boris Anukhin ,  Mikael Trollsas ,  Lewis B. Schwartz

IPC: A61F2/86

CPC classification number: A61F2/915 ,  A61F2/86 ,  A61F2/89 ,  A61F2/90 ,  A61F2/958 ,  A61F2002/826 ,  A61F2002/9155 ,  A61F2002/91591 ,  A61F2210/00 ,  A61F2230/0013 ,  A61F2230/0054 ,  A61F2240/001 ,  B29C35/0805 ,  B29C65/64 ,  B29C66/1248 ,  B29C66/71 ,  B29C2035/0838 ,  B29K2067/046 ,  B29K2995/006 ,  B29L2031/7534

Abstract: Segmented scaffolds composed of disconnected scaffold segments with overlapping end rings are disclosed. Scaffolds with at least one discontinuous link are also disclosed.

Abstract translation: 公开了由具有重叠端环的断开的支架段组成的分段支架。 还公开了具有至少一个不连续链节的支架。