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公开(公告)号：US20150086603A1
公开(公告)日：2015-03-26
申请号：US14557299
申请日：2014-12-01
Applicant: Abbott Cardiovascular Systems Inc.
Inventor： Syed F.A. Hossainy , Dariush Davalian , Jinping Wan , Hong Ma
CPC classification number: A61L31/06 , A61K9/0024 , A61K9/127 , A61K9/5153 , A61K9/5192 , A61L31/00
Abstract: The present invention relates to implantable medical devices containing surface-treated, dual-targeted drug carriers for treating vascular diseases.
Abstract translation: 本发明涉及包含用于治疗血管疾病的表面处理的双靶向药物载体的可植入医疗装置。
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2.发明申请REGIONAL DELIVERY OF THERAPEUTIC AGENTS FOR THE TREATMENT OF VASCULAR DISEASES 审中-公开用于治疗血管疾病的治疗药物的区域性递送公开(公告)号：US20150045877A1
公开(公告)日：2015-02-12
申请号：US14521126
申请日：2014-10-22
Applicant: Abbott Cardiovascular Systems Inc.
Inventor： Stephen D. Pacetti , Paul M. Consigny , Ronald W. Heil, JR. , Florian Niklas Ludwig , Dariush Davalian , Li Zhao , Irinia Astafieva , Jinping Wan , Fozan EI-Nounou , Katsuyuki Murase , Syed F.A. Hossainy , Rachel Bright , Jeffrey Ellis
CPC classification number: A61M25/1002 , A61F2/82 , A61F2250/0067 , A61K31/27 , A61K31/44 , A61K31/56 , A61K31/66 , A61K38/1709 , A61L29/08 , A61L29/16 , A61L31/08 , A61L31/16 , A61L2300/112 , A61L2300/216 , A61L2300/252 , A61L2300/40 , A61L2300/41 , A61L2300/416 , A61L2300/606 , A61L2300/62 , A61M25/10 , A61M37/0015 , A61M2025/105 , A61M2025/1086 , A61M2037/0023 , A61M2037/0061 , A61M2210/12
Abstract: The present invention relates to the regional delivery of therapeutic agents for the treatment of vascular diseases wherein regional delivery refers to delivery of a therapeutically effective amount of the therapeutic agent to an area of the vessel that includes not only afflicted tissue but non-afflicted tissue at the periphery of the afflicted tissue as well.
Abstract translation: 本发明涉及用于治疗血管疾病的治疗剂的区域递送，其中区域递送是指将治疗有效量的治疗剂递送至血管的区域，该区域不仅包括受到损伤的组织而且包括非折磨组织 受影响组织的外围也是如此。
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公开(公告)号：US09289318B2
公开(公告)日：2016-03-22
申请号：US14656553
申请日：2015-03-12
Applicant: Abbott Cardiovascular Systems Inc.
Inventor： Mikael Trollsas , Dariush Davalian , Michael Huy Ngo , Hao-Ming Hsiao , Boris Anukhin , Syed Hossainy , David Gale
CPC classification number: A61F2/89 , A61F2/91 , A61F2/915 , A61F2002/828 , A61F2210/0004 , A61F2230/0054 , A61F2250/0036 , A61L31/06 , A61L31/10 , A61L31/148 , C08L67/04
Abstract: A bioabsorbable polymeric stent with time dependent structure and properties and methods of treating a diseased blood vessel with the bioabsorable polymeric stent are disclosed. The structure and properties of the stent change with time and allow the vessel to be restored to a natural unstented state. The bioabsorbable stent loses mechanical integrity in a controlled manner due to modification of selected structural elements.
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4.发明申请公开(公告)号：US20150024039A1
公开(公告)日：2015-01-22
申请号：US14506038
申请日：2014-10-03
Applicant: Abbott Cardiovascular Systems Inc.
Inventor： Dariush Davalian , Stephen Pacetti , Florian Niklas Ludwig , Syed Faiyaz Ahmed Hossainy , Irina Astafieva , Kimchi Tran
IPC: A61K9/00
CPC classification number: A61K9/0019 , A61F2/95 , A61L29/16 , A61L31/16 , A61L2300/416 , A61L2300/62 , A61M25/0084 , A61M25/104 , A61M2025/105
Abstract: This invention relates to methods of enhancing the permeability of blood vessels to therapeutic agents.
Abstract translation: 本发明涉及增强血管对治疗剂的渗透性的方法。
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公开(公告)号：US20140377332A1
公开(公告)日：2014-12-25
申请号：US14086907
申请日：2013-11-21
Applicant: Abbott Cardiovascular Systems Inc.
Inventor： Florian N. Ludwig , Stephen D. Pacetti , Syed F.A. Hossainy , Dariush Davalian
CPC classification number: A61K9/5031 , A61K9/0004 , A61K9/0019 , A61K9/5115 , A61K9/5138 , A61K38/446 , A61K41/0052 , A61K47/6923 , A61K47/6925 , A61K47/6929 , A61K47/6931 , A61L31/16 , A61L2300/00 , A61L2400/06 , A61L2400/12 , B01J13/02 , B22F1/025 , B82Y5/00 , Y10S977/773 , Y10S977/906 , Y10T428/2991 , Y10T428/2998
Abstract: Nano-constructs comprising nanoshells and methods of using the nano-constructs for treating or ameliorating a medical condition are provided.
Abstract translation: 提供包含纳米壳的纳米构建体和使用纳米构建体治疗或改善医学状况的方法。
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Patent Agency Ranking
6.发明授权公开(公告)号：US08895056B2
公开(公告)日：2014-11-25
申请号：US13725525
申请日：2012-12-21
Applicant: Abbott Cardiovascular Systems Inc.
Inventor： Stephen D. Pacetti , Paul M. Consigny , Ronald W. Heil, Jr. , Florian Niklas Ludwig , Dariush Davalian , Li Zhao , Irina Astafieva , Jinping Wan , Fozan El-Nounou , Katsuyuki Murase , Syed F. A. Hossainy , Rachel Bright , Jeffrey Ellis
CPC classification number: A61M25/1002 , A61F2/82 , A61F2250/0067 , A61K31/27 , A61K31/44 , A61K31/56 , A61K31/66 , A61K38/1709 , A61L29/08 , A61L29/16 , A61L31/08 , A61L31/16 , A61L2300/112 , A61L2300/216 , A61L2300/252 , A61L2300/40 , A61L2300/41 , A61L2300/416 , A61L2300/606 , A61L2300/62 , A61M25/10 , A61M37/0015 , A61M2025/105 , A61M2025/1086 , A61M2037/0023 , A61M2037/0061 , A61M2210/12
Abstract: The present invention relates to the regional delivery of therapeutic agents for the treatment of vascular diseases wherein regional delivery refers to delivery of a therapeutically effective amount of the therapeutic agent to an area of the vessel that includes not only afflicted tissue but non-afflicted tissue at the periphery of the afflicted tissue as well.
Abstract translation: 本发明涉及用于治疗血管疾病的治疗剂的区域递送，其中区域递送是指将治疗有效量的治疗剂递送至血管的区域，该区域不仅包括受到损伤的组织而且包括非折磨组织 受影响组织的外围也是如此。
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7.发明申请BIOABSORBABLE STENT WITH TIME DEPENDENT STRUCTURE AND PROPERTIES AND REGIO-SELECTIVE DEGRADATION 审中-公开具有时间依赖结构和特性的生物可降解性和选择性降解公开(公告)号：US20130245746A1
公开(公告)日：2013-09-19
申请号：US13866984
申请日：2013-04-19
Applicant: ABBOTT CARDIOVASCULAR SYSTEMS INC.
Inventor： Mikael TROLLSAS , Dariush Davalian , Michael Huy Ngo , Hao-Ming Hsiao , Boris Anukhin , Syed F.A. Hossainy , David C. Gale
IPC: A61F2/89
CPC classification number: A61F2/89 , A61F2/91 , A61F2/915 , A61F2002/828 , A61F2210/0004 , A61F2230/0054 , A61F2250/0036 , A61L31/06 , A61L31/10 , A61L31/148 , C08L67/04
Abstract: A bioabsorbable polymeric stent with time dependent structure and properties and methods of treating a diseased blood vessel with the bioabsorable polymeric stent are disclosed. The structure and properties of the stent change with time and allow the vessel to be restored to a natural unstented state. The bioabsorbable stent loses mechanical integrity in a controlled manner due to modification of selected structural elements.
Abstract translation: 公开了具有时间依赖性结构的生物可吸收聚合物支架，以及用生物可吸收聚合物支架治疗患病血管的特性和方法。 支架的结构和性质随时间而变化，并允许血管恢复到自然不稳定状态。 由于选择的结构元件的修饰，生物可吸收的支架以受控的方式失去机械完整性。
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8.发明申请DEVICES AND METHODS FOR TREATMENT OF THE EUSTACHIAN TUBE AND SINUS CAVITY 审中-公开用于治疗EUSTACHIAN TUBE和SINUS CAVITY的装置和方法公开(公告)号：US20170027724A1
公开(公告)日：2017-02-02
申请号：US15290886
申请日：2016-10-11
Applicant: Abbott Cardiovascular Systems Inc.
Inventor： Syed Hossainy , Paul Consigny , Dariush Davalian , James Su , Michael Ngo , Adrain Gale , Jesus Magana , Mikael Trollsas , Evan Norton , Benjamyn Serna
CPC classification number: A61F2/958 , A61B1/06 , A61F2/915 , A61F11/002 , A61F2002/91575 , A61F2002/91583 , A61F2230/0067 , A61F2250/0018 , A61F2250/0026 , A61F2250/0046 , A61F2250/0048 , A61F2250/005 , A61F2250/0082 , A61M25/10 , A61M29/02 , A61M2025/105 , A61M2025/1059 , A61M2210/0675
Abstract: A polymeric stent can be implanted for treatment of the Eustachian tube. The stent can be designed to have length-dependent radial strength to allow it to stay within the Eustachian tube and to allow normal closing and opening of the Eustachian tube. A balloon can be used to implant the stent, and the balloon can be coated with a therapeutic agent. A coated balloon can also be used to transfer therapeutic agents to the sinus cavity during a balloon sinus dilation procedure.
Abstract translation: 可以植入聚合物支架以治疗咽鼓管。 支架可以设计成具有长度依赖的径向强度，以允许其保持在咽鼓管内并允许正常的关闭和打开咽鼓管。 可以使用气囊来植入支架，并且可以用治疗剂涂覆气囊。 在气球窦扩张过程中，涂覆的气囊也可以用于将治疗剂转移到窦腔。
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9.发明申请公开(公告)号：US20150119976A1
公开(公告)日：2015-04-30
申请号：US14066330
申请日：2013-10-29
Applicant: Abbott Cardiovascular Systems Inc.
Inventor： Paul Consigny , Dariush Davalian
CPC classification number: A61L31/148 , A61B17/11 , A61B17/12009 , A61B2017/1107 , A61M1/3655 , Y10T83/04
Abstract: A medical device that can be wrapped around a segment of an artery downstream of an arteriovenous fistula. The wrap, when used in this manner, creates a stenosis for reducing retrograde flow at the fistula. Sutures are positioned in holes present in the upper and lower halves or connecting ends of the wrap, after which the sutures are pulled to oppose the two sides in order to create a stenosis. When the surgeon is satisfied that the stenosis is appropriate, the sutures are tied in place.
Abstract translation: 可以在动静脉瘘下游缠绕动脉的一段的医疗装置。 当以这种方式使用时，包装形成了减少瘘管逆行流动的狭窄。 缝合线定位在存在于上部和下部半部或包裹物的连接端的孔中，之后将缝合线拉动以与两侧相对以形成狭窄。 当外科医生认为狭窄是合适的时候，缝线被绑在一起。
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10.发明授权公开(公告)号：US09510976B2
公开(公告)日：2016-12-06
申请号：US14265343
申请日：2014-04-29
Applicant: ABBOTT CARDIOVASCULAR SYSTEMS INC.
Inventor： Syed Hossainy , Paul Consigny , Dariush Davalian , James Su , Michael Ngo , Adrain Gale , Jesus Magana , Mikael Trollsas , Evan Norton , Benjamyn Serna
CPC classification number: A61F2/958 , A61B1/06 , A61F2/915 , A61F11/002 , A61F2002/91575 , A61F2002/91583 , A61F2230/0067 , A61F2250/0018 , A61F2250/0026 , A61F2250/0046 , A61F2250/0048 , A61F2250/005 , A61F2250/0082 , A61M25/10 , A61M29/02 , A61M2025/105 , A61M2025/1059 , A61M2210/0675
Abstract: A polymeric stent can be implanted for treatment of the Eustachian tube. The stent can be designed to have length-dependent radial strength to allow it to stay within the Eustachian tube and to allow normal closing and opening of the Eustachian tube. A balloon can be used to implant the stent, and the balloon can be coated with a therapeutic agent. A coated balloon can also be used to transfer therapeutic agents to the sinus cavity during a balloon sinus dilation procedure.
Abstract translation: 可以植入聚合物支架以治疗咽鼓管。 支架可以设计成具有长度依赖的径向强度，以允许其保持在咽鼓管内并允许正常的关闭和打开咽鼓管。 可以使用气囊来植入支架，并且可以用治疗剂涂覆气囊。 在气球窦扩张过程中，涂覆的气囊也可以用于将治疗剂转移到窦腔。
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