公开(公告)号：US08014961B2

公开(公告)日：2011-09-06

申请号：US11677505

申请日：2007-02-21

Applicant: Steven H. Bass ,  Simon Christopher Davis ,  Phillip A. Patten ,  Matthew Tobin ,  Jeremy S. Minshull ,  Mark Welch ,  Claus Gustafsson ,  Brian Carr ,  Stephan J. Jenne ,  Sun Ai Raillard ,  Andreas Crameri ,  Willem P. C. Stemmer ,  Robin Emig ,  Pascal Longchamp ,  Stanley Goldman ,  Lorraine J. Giver ,  Joseph A. Affholter

Inventor： Steven H. Bass ,  Simon Christopher Davis ,  Phillip A. Patten ,  Matthew Tobin ,  Jeremy S. Minshull ,  Mark Welch ,  Claus Gustafsson ,  Brian Carr ,  Stephan J. Jenne ,  Sun Ai Raillard ,  Andreas Crameri ,  Willem P. C. Stemmer ,  Robin Emig ,  Pascal Longchamp ,  Stanley Goldman ,  Lorraine J. Giver ,  Joseph A. Affholter

IPC: G01N33/48

CPC classification number: C12N15/1031 ,  B01J19/0046 ,  B01J2219/00378 ,  B01J2219/00585 ,  B01J2219/00659 ,  B01J2219/00675 ,  B01J2219/00689 ,  B01J2219/00695 ,  B01J2219/007 ,  B01J2219/00722 ,  B82Y30/00 ,  C12N15/1027 ,  C40B60/04 ,  G06F19/18 ,  Y02A90/22

Abstract: Integrated systems and methods for diversity generation and screening are provided. The systems use common fluid and array handling components to provide nucleic acid diversification, transcription, translation, product screening and subsequent diversification reactions.

Abstract translation: 提供了用于多样化生成和筛选的集成系统和方法。 该系统使用普通液体和阵列处理组分来提供核酸多样化，转录，翻译，产物筛选和随后的多样化反应。

公开(公告)号：US20090118130A1

公开(公告)日：2009-05-07

申请号：US12069869

申请日：2008-02-12

Applicant: Emily Mundorff ,  Simon Christopher Davis ,  Gjalt W. Huisman ,  Anke Krebber ,  John H. Grate

Inventor： Emily Mundorff ,  Simon Christopher Davis ,  Gjalt W. Huisman ,  Anke Krebber ,  John H. Grate

IPC: C40B30/00 ,  C40B40/10 ,  C12Q1/25 ,  C40B40/02 ,  C40B50/14 ,  C12N5/10 ,  C12N9/00

CPC classification number: C12Q1/25 ,  C12N9/00 ,  C12N15/1093 ,  C12Q1/00 ,  C12Q1/26 ,  C40B10/00 ,  C40B30/04 ,  C40B40/02 ,  C40B40/10 ,  G01N33/6803 ,  G01N33/6845 ,  G16B20/00

Abstract: The present disclosure relates to compositions and methods for screening a plurality of polypeptide variants.

Abstract translation: 本公开涉及用于筛选多种多肽变体的组合物和方法。