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公开(公告)号：US10316352B2
公开(公告)日：2019-06-11
申请号：US12465323
申请日：2009-05-13
IPC分类号： C12Q1/68 , C07H21/00 , C12Q1/6816 , C12Q1/6832 , C12Q1/6834 , C12Q1/686
摘要： The present invention provides compositions, kits and methods for the selective hybridization and capture of a specific target nucleic acid. The specific target nucleic acid may be present in a heterogeneous mixture of nucleic acids. Selective hybridization and capture provides a target nucleic acid that is substantially free of non-target and/or contaminating nucleic acids. Target nucleic acids that have been selectively hybridized and captured using the current invention are then used in subsequent analysis, wherein the presence of non-target and/or contaminating nucleic acids that interfere with said subsequent analysis have been substantially reduced or eliminated, thereby providing improved analysis results. The invention offers the further advantage of requiring less stringent purification and/or sterility efforts than conventionally needed in order to ensure that enzymes and other reagents used in subsequent analysis, or present in the environment in which an assay is performed, are free of bacterial or other contaminating nucleic acids.
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公开(公告)号：US20150046599A1
公开(公告)日：2015-02-12
申请号：US13246511
申请日：2011-09-27
申请人： Sergey Ulanov , Alberto Martin , Albert Wong , Hin Chung Lam , Gary Kacmarcik , David Maclachlan
发明人： Sergey Ulanov , Alberto Martin , Albert Wong , Hin Chung Lam , Gary Kacmarcik , David Maclachlan
IPC分类号： G06F15/16
CPC分类号： H04N21/64707 , H04L65/608 , H04L67/38 , H04L67/40 , H04L69/14 , H04L69/18
摘要： In a general aspect, a computer-readable storage medium stores instructions that when executed cause a processor to perform a process. The instructions can include instructions to transmit video data of a remote desktop session to a client via a first data channel using a first protocol. The instructions can also include instructions to transmit event data of the remote desktop session to the client via a second data channel using a second protocol, the second protocol being different than the first protocol.
摘要翻译： 在一般方面，计算机可读存储介质存储当执行时导致处理器执行处理的指令。 指令可以包括通过使用第一协议经由第一数据信道将远程桌面会话的视频数据传送到客户端的指令。 所述指令还可以包括通过使用第二协议经由第二数据信道将远程桌面会话的事件数据传送到客户端的指令，所述第二协议不同于第一协议。
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公开(公告)号：US20120308191A1
公开(公告)日：2012-12-06
申请号：US13589611
申请日：2012-08-20
申请人： Hing Yip Chung , Fuk Sang Mak , Golan Levy , Wai Chung Lam , Chong Va Cheong , Shiu Hang Tsang
发明人： Hing Yip Chung , Fuk Sang Mak , Golan Levy , Wai Chung Lam , Chong Va Cheong , Shiu Hang Tsang
IPC分类号： H04N5/76
CPC分类号： H04N5/7605 , H04N5/765 , H04N5/77 , H04N7/181 , H04N7/185 , H04N21/2747
摘要： Embodiments disclosed herein provide systems and methods for performing video recorder failover. In a particular embodiment, a system includes a first Network Video Recorder (NVR) configured to receive a video stream and record the video stream to a first long-term storage. The system further includes a second NVR configured to receive the video stream and temporarily stores an amount of the video stream in temporary storage. In response to a detection of a failure of the first NVR, the second NVR is configured to record the video stream to the second long-term storage and transfer at least a portion of the video stream stored in the temporary storage corresponding to the amount of time between detection of the failure and when the second NVR began recording the video stream to the second long-term storage.
摘要翻译： 本文公开的实施例提供了用于执行录像机故障切换的系统和方法。 在特定实施例中，系统包括被配置为接收视频流并将视频流记录到第一长期存储器的第一网络视频记录器（NVR）。 该系统还包括被配置为接收视频流并将视频流的量临时存储在临时存储中的第二NVR。 响应于对第一NVR的故障的检测，第二NVR被配置为将视频流记录到第二长期存储并且传送存储在临时存储器中的视频流的至少一部分，对应于 检测到故障与第二个NVR开始将视频流录制到第二个长期存储器之间的时间。
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4.发明授权公开(公告)号：US08278052B2
公开(公告)日：2012-10-02
申请号：US13231848
申请日：2011-09-13
CPC分类号： C12Q1/6848 , C12N15/1065 , C12Q1/6806 , C12Q1/689 , C12Q1/6895 , C12Q2525/155
摘要： The present invention provides kits containing tagged oligonucleotides for use in certain nucleic acid amplification methods to desirably reduce or eliminate false positive amplification signals resulting from contaminating biological material, e.g., nucleic acid, that may be present in one or more reagents used in an amplification reaction and/or that may be present in the environment in which an amplification reaction is performed. The kits containing tagged oligonucleotides can be used in purification and/or sterility efforts under less stringent conditions than conventionally needed to reduce or eliminate false positive results in a nucleic acid amplification method.
摘要翻译： 本发明提供了含有用于某些核酸扩增方法中的标记的寡核苷酸的试剂盒，用于期望地减少或消除由可能存在于用于扩增反应的一种或多种试剂中的生物材料例如核酸引起的假阳性扩增信号 和/或其可以存在于进行扩增反应的环境中。 含有标记的寡核苷酸的试剂盒可以在比通常在减少或消除核酸扩增方法中的假阳性结果所需的不严格条件下用于纯化和/或不育的努力。
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公开(公告)号：US08230009B1
公开(公告)日：2012-07-24
申请号：US13246200
申请日：2011-09-27
申请人： Albert Wong , Hin Chung Lam , Sergey Ulanov , Gary Kacmarcik
发明人： Albert Wong , Hin Chung Lam , Sergey Ulanov , Gary Kacmarcik
IPC分类号： G06F15/16
CPC分类号： H04L12/6418
摘要： In one general aspect, a computer-readable storage medium can store instructions that when executed cause a client device to perform a process. The instructions comprising instructions to define a plurality of event packets where each event packet from the plurality of event packets includes an input value from a user interface device associated with the client device, and instructions to define, at a first time, a first carrier packet including the plurality of event packets. The instructions can also include instructions to define an additional event packet representing an additional input value from the user interface device associated with the client device, and define, at a second time, a second carrier packet including the additional event packet and at least a portion of the plurality of event packets.
摘要翻译： 在一个一般方面，计算机可读存储介质可以存储指令，当执行时，使得客户端设备执行处理。 所述指令包括定义多个事件分组的指令，其中来自所述多个事件分组的每个事件分组包括来自与所述客户机设备相关联的用户界面设备的输入值，以及在第一时间定义第一载波分组 包括多个事件分组。 指令还可以包括用于定义表示来自与客户端设备相关联的用户界面设备的附加输入值的附加事件分组的指令，并且在第二时间定义包括附加事件分组的第二载波分组和至少一部分 的多个事件分组。
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公开(公告)号：US08183359B2
公开(公告)日：2012-05-22
申请号：US12716052
申请日：2010-03-02
IPC分类号： C07H21/04
CPC分类号： C12P19/34 , C12Q1/6865 , C12Q2533/101 , C12Q2525/186 , C12Q2525/143
摘要： Kits for amplifying DNA which include a priming oligonucleotide that hybridizes to a 3′-end of a DNA target sequence, a displacer oligonucleotide that hybridizes to a target nucleic acid containing the DNA target sequence at a position upstream from the priming oligonucleotide, and a promoter oligonucleotide that includes a region that hybridizes to a 3′-region of a DNA primer extension product that includes the priming oligonucleotide and a promoter for an RNA polymerase. The priming oligonucleotide does not include an RNA region that hybridizes to the target nucleic acid and is selectively degraded by an enzyme activity when hybridized to the target nucleic acid. The kits do not include a restriction endonuclease and oligonucleotides that include a promoter for an RNA polymerase are all modified to prevent the initiation of DNA synthesis therefrom.
摘要翻译： 用于扩增DNA的试剂盒，其包含与DNA靶序列的3'端杂交的引物寡核苷酸，与引物寡核苷酸上游位置含有DNA靶序列的靶核酸杂交的置换者寡核苷酸，以及启动子 包括与包含引发寡核苷酸的DNA引物延伸产物的3'区域和RNA聚合酶的启动子杂交的区域的寡核苷酸。 引发寡核苷酸不包括与靶核酸杂交的RNA区域，并且当与靶核酸杂交时被选择性地被酶活性降解。 试剂盒不包括限制性内切核酸酶，并且包括RNA聚合酶的启动子的寡核苷酸都被修饰以防止从其中开始DNA合成。
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7.发明授权公开(公告)号：US08034570B2
公开(公告)日：2011-10-11
申请号：US12892323
申请日：2010-09-28
CPC分类号： C12Q1/6848 , C12N15/1065 , C12Q1/6806 , C12Q1/689 , C12Q1/6895 , C12Q2525/155
摘要： Disclosed are methods for selective amplification of target nucleic acid sequence using a tagged oligonucleotide comprising a target hybridizing sequence that hybridizes to a 3′-end of the target nucleic acid and a tag sequence situated 5′ to the target hybridizing sequence. The tagged oligonucleotide is hybridized to the target nucleic acid and, after reducing the effective concentration of unhybridized tagged oligonucleotide having an active form, a primer extension reaction is initiated to produce a primer extension product. Further amplification also utilizes a first oligonucleotide that hybridizes to the 3′ end of the complement of the target nucleic acid and a second oligonucleotide that hybridizes to the complement of the tag sequence. Also disclosed are reaction mixtures for use in the disclosed methods comprising the tagged oligonucleotide hybridized to target nucleic and substantially free of an active form of unhybridized tagged oligonucleotide.
摘要翻译： 公开了使用包含与靶核酸的3'-末端杂交的靶杂交序列和位于靶标杂交序列5'的标签序列的标记寡核苷酸选择性扩增靶核酸序列的方法。 标记的寡核苷酸与靶核酸杂交，并且在降低具有活性形式的未杂交标记的寡核苷酸的有效浓度之后，引发引物延伸反应以产生引物延伸产物。 进一步扩增还利用与靶核酸的补体的3'端杂交的第一寡核苷酸和与标签序列的互补杂交的第二寡核苷酸。 还公开了用于所公开方法的反应混合物，其包含与靶核酸杂交的基本上不含活性形式的未杂交标记的寡核苷酸的标记寡核苷酸。
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公开(公告)号：US20070215874A1
公开(公告)日：2007-09-20
申请号：US11378492
申请日：2006-03-17
申请人： Toshiharu Furukawa , Mark Hakey , Steven Holmes , David Horak , Charles Koburger , Chung Lam
发明人： Toshiharu Furukawa , Mark Hakey , Steven Holmes , David Horak , Charles Koburger , Chung Lam
IPC分类号： H01L23/58
CPC分类号： H01L21/32139 , H01L21/0337 , H01L21/0338 , H01L21/76885 , H01L21/76895 , H01L23/528 , H01L2224/06 , H01L2924/0002 , H01L2924/00
摘要： An integrated circuit and method for fabrication includes first and second structures, each including a set of sub-lithographic lines, and contact landing segments connected to at least one of the sub-lithographic lines at an end portion. The first and second structures are nested such that the sub-lithographic lines are disposed in a parallel manner within a width, and the contact landing segments of the first structure are disposed on an opposite side of a length of the sub-lithographic lines relative to the contact landing segments of the second structure. The contact landing segments for the first and second structures are included within the width dimension, wherein the width includes a dimension four times a minimum feature size achievable by lithography.
摘要翻译： 一种用于制造的集成电路和方法，包括第一和第二结构，每个结构包括一组子光刻线，以及在端部处连接到至少一个子光刻线的接触着陆段。 第一和第二结构被嵌套，使得亚光刻线以平行方式设置在宽度内，并且第一结构的接触着陆段被设置在相对于子平版印刷线的相对侧的相对侧 第二结构的接触着陆段。 用于第一和第二结构的接触着陆段包括在宽度尺寸内，其中宽度包括通过光刻实现的最小特征尺寸的四倍的尺寸。
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公开(公告)号：US20070136523A1
公开(公告)日：2007-06-14
申请号：US11635926
申请日：2006-12-08
申请人： Randy Bonella , Chung Lam
发明人： Randy Bonella , Chung Lam
IPC分类号： G06F13/00
CPC分类号： G06F12/0866 , G06F9/4401 , G06F2212/2022 , G06F2212/2112 , G06F2212/2515
摘要： A memory module including a volatile memory, a non-volatile memory, and a controller that provides address, data, and control interfaces to the memories and to a host system, such as, for example, a personal computer, is operable to interact with the host system so as to provide one or more additional layers in the memory hierarchy of the host system. In one aspect of the present invention the controller operates the volatile memory of the memory module as a cache for the non-volatile memory of the memory module. In another aspect of the present invention data representing one or more software applications and/or one or more data sets are stored in the non-volatile memory of the memory module along with security information such that a host system may quickly launch applications from the memory module rather than from a slower hard disk drive.
摘要翻译： 包括易失性存储器，非易失性存储器和向存储器和主机系统（例如个人计算机）提供地址，数据和控制接口的控制器的存储器模块可操作以与 主机系统，以便在主机系统的存储器层级中提供一个或多个附加层。 在本发明的一个方面，控制器将存储器模块的易失性存储器作为存储器模块的非易失性存储器的缓存器进行操作。 在本发明的另一方面，代表一个或多个软件应用和/或一个或多个数据集的数据与安全信息一起存储在存储器模块的非易失性存储器中，使得主机系统可以从存储器快速启动应用 模块，而不是从较慢的硬盘驱动器。
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10.发明申请公开(公告)号：US20070128776A1
公开(公告)日：2007-06-07
申请号：US11670262
申请日：2007-02-01
申请人： Matthew Breitwisch , Chung Lam , Randy Mann , Dale Martin
发明人： Matthew Breitwisch , Chung Lam , Randy Mann , Dale Martin
CPC分类号： H01L21/764 , H01L21/76283 , H01L21/76289 , H01L29/78654
摘要： The present invention provides a method of forming an ultra-thin and uniform layer of Si including the steps of providing a substrate having semiconducting regions separated by insulating regions; implanting dopants into the substrate to provide an etch differential doped portion in the semiconducting regions underlying an upper Si-containing surface of the semiconducting regions; forming a trench in the substrate including the semiconducting regions and the insulating regions; removing the etch differential doped portion from the semiconductor regions to produce a cavity underlying the upper surface of the semiconducting regions; and filling the trench with a trench dielectric, wherein the trench dielectric material encloses the cavity underlying the upper Si-containing surface of the semiconducting regions. The upper Si-containing surface of the semiconducting regions has a uniform thickness of less than about 100 Å.
摘要翻译： 本发明提供一种形成超薄且均匀的Si层的方法，包括以下步骤：提供具有由绝缘区分隔开的半导体区域的衬底; 将掺杂剂注入衬底中以在半导体区域的上部含Si表面下方的半导体区域中提供蚀刻差分掺杂部分; 在包括半导体区域和绝缘区域的衬底中形成沟槽; 从所述半导体区域去除所述蚀刻差分掺杂部分以在所述半导体区域的上表面下方形成空腔; 以及用沟槽电介质填充所述沟槽，其中所述沟槽电介质材料包围在所述半导体区域的所述上部含Si表面之下的空腔。 半导体区域的上部含Si表面具有小于约的均匀厚度。
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