公开(公告)号：US20170095173A1

公开(公告)日：2017-04-06

申请号：US15380340

申请日：2016-12-15

Applicant: BIOSENSE WEBSTER (ISRAEL) LTD.

Inventor： Meir Bar-Tal ,  Richard P.M. Houben ,  Yaniv Ben Zriham ,  Assaf Pressman ,  Roy Urman ,  Shmuel Auerbach

IPC: A61B5/046 ,  A61B34/20 ,  A61B5/00 ,  A61B5/04 ,  A61B5/042

CPC classification number: A61B5/046 ,  A61B5/04012 ,  A61B5/0422 ,  A61B5/0428 ,  A61B5/0456 ,  A61B5/7203 ,  A61B5/7221 ,  A61B5/7235 ,  A61B5/726 ,  A61B18/1492 ,  A61B34/20 ,  A61B2018/0016 ,  A61B2018/00267 ,  A61B2018/00839 ,  A61B2034/2051

Abstract: Catheterization of the heart is carried out by inserting a probe having electrodes into a heart of a living subject, recording a bipolar electrogram and a unipolar electrogram from one of the electrodes at a location in the heart, and defining a window of interest wherein a rate of change in a potential of the bipolar electrogram exceeds a predetermined value. An annotation is established in the unipolar electrogram, wherein the annotation denotes a maximum rate of change in a potential of the unipolar electrogram within the window of interest. A quality value is assigned to the annotation, and a 3-dimensional map is generated of a portion of the heart that includes the annotation and the quality value thereof.

公开(公告)号：US20170079589A1

公开(公告)日：2017-03-23

申请号：US15369668

申请日：2016-12-05

Applicant: MC10, Inc.

Inventor： Roozbeh Ghaffari ,  Stephen P. Lee ,  Brian David Elolampi

IPC: A61B5/00 ,  A61B18/20 ,  A61M25/10 ,  A61B5/1473 ,  A61B5/042 ,  A61B5/0408 ,  A61B5/03 ,  A61B5/145 ,  A61B18/14 ,  A61B5/0205

CPC classification number: A61B5/6853 ,  A61B5/0084 ,  A61B5/01 ,  A61B5/02055 ,  A61B5/0215 ,  A61B5/02405 ,  A61B5/036 ,  A61B5/04087 ,  A61B5/042 ,  A61B5/0422 ,  A61B5/044 ,  A61B5/046 ,  A61B5/053 ,  A61B5/0538 ,  A61B5/14539 ,  A61B5/14546 ,  A61B5/1473 ,  A61B5/4836 ,  A61B5/6833 ,  A61B5/6885 ,  A61B18/02 ,  A61B18/1492 ,  A61B18/20 ,  A61B2018/0016 ,  A61B2018/0022 ,  A61B2018/00357 ,  A61B2018/00577 ,  A61B2018/00648 ,  A61B2018/00839 ,  A61B2018/0212 ,  A61B2018/0237 ,  A61B2018/0262 ,  A61B2562/0215 ,  A61B2562/0247 ,  A61B2562/0261 ,  A61B2562/125 ,  A61B2562/164 ,  A61M25/10 ,  A61M2025/105 ,  A61N7/00 ,  Y10T156/10

Abstract: An apparatus for medical diagnosis and/or treatment is provided. The apparatus includes a flexible substrate, an intermediate bus disposed on the flexible substrate, and a plurality of sensing elements disposed on the flexible substrate and coupled to the intermediate bus. The plurality of sensing elements and intermediate bus are disposed on the flexible substrate such that the sensing elements are disposed at areas of minimal strain of the flexible substrate.

公开(公告)号：US20170079588A1

公开(公告)日：2017-03-23

申请号：US15369627

申请日：2016-12-05

Applicant: MC10, Inc.

Inventor： Roozbeh Ghaffari ,  Stephen P. Lee ,  Brian David Elolampi

IPC: A61B5/00 ,  A61B18/14 ,  A61B5/0205 ,  A61B5/042 ,  A61B5/046

CPC classification number: A61B5/6853 ,  A61B5/0084 ,  A61B5/01 ,  A61B5/02055 ,  A61B5/0215 ,  A61B5/02405 ,  A61B5/036 ,  A61B5/04087 ,  A61B5/042 ,  A61B5/0422 ,  A61B5/044 ,  A61B5/046 ,  A61B5/053 ,  A61B5/0538 ,  A61B5/14539 ,  A61B5/14546 ,  A61B5/1473 ,  A61B5/4836 ,  A61B5/6833 ,  A61B5/6885 ,  A61B18/02 ,  A61B18/1492 ,  A61B18/20 ,  A61B2018/0016 ,  A61B2018/0022 ,  A61B2018/00357 ,  A61B2018/00577 ,  A61B2018/00648 ,  A61B2018/00839 ,  A61B2018/0212 ,  A61B2018/0237 ,  A61B2018/0262 ,  A61B2562/0215 ,  A61B2562/0247 ,  A61B2562/0261 ,  A61B2562/125 ,  A61B2562/164 ,  A61M25/10 ,  A61M2025/105 ,  A61N7/00 ,  Y10T156/10

Abstract: An apparatus for medical diagnosis and/or treatment is provided. The apparatus includes a flexible substrate, an intermediate bus disposed on the flexible substrate, and a plurality of sensing elements disposed on the flexible substrate and coupled to the intermediate bus. The plurality of sensing elements and intermediate bus are disposed on the flexible substrate such that the sensing elements are disposed at areas of minimal strain of the flexible substrate.

公开(公告)号：US20170079542A1

公开(公告)日：2017-03-23

申请号：US15369483

申请日：2016-12-05

Applicant: University of Vermont

Inventor： Peter S. SPECTOR

IPC: A61B5/042 ,  A61B5/06 ,  A61B5/0452 ,  A61B18/14 ,  A61B5/00 ,  A61B5/046

CPC classification number: A61B5/0422 ,  A61B5/04014 ,  A61B5/04017 ,  A61B5/04525 ,  A61B5/046 ,  A61B5/068 ,  A61B5/4836 ,  A61B5/6852 ,  A61B5/6885 ,  A61B18/1492 ,  A61B34/20 ,  A61B2018/00351 ,  A61B2018/00577 ,  A61B2018/00839 ,  A61B2034/2051 ,  A61B2505/05 ,  A61B2562/046

Abstract: Catheters, systems, and related methods for optimized for mapping, minimizing, and treating cardiac fibrillation in a patient, including an array of at least one stacked electrode pair, each electrode pair including a first electrode and a second electrode, wherein each electrode pair is configured to be orthogonal to a surface of a cardiac tissue substrate, wherein each first electrode is in contact with the surface to record a first signal, and wherein each second electrode is separated from the first electrode by a distance which enables the second electrode to record a second signal, wherein the catheter is configured to obtain one or more measurements from at least a first signal and a second signal in response to electrical activity in the cardiac tissue substrate indicative of a number of electrical circuit cores and distribution of the electrical circuit cores for a duration across the cardiac tissue substrate.

公开(公告)号：US09592012B2

公开(公告)日：2017-03-14

申请号：US15048641

申请日：2016-02-19

Applicant: Physio-Control, Inc.

Inventor： Joseph L. Sullivan ,  Robert G. Walker

IPC: A61B5/04 ,  A61B5/00 ,  A61B5/0402 ,  A61B5/083 ,  A61M16/00 ,  A61B5/087 ,  A61H31/00 ,  A61N1/39 ,  A61B5/046 ,  A61B5/053

CPC classification number: A61B5/7217 ,  A61B5/0205 ,  A61B5/04017 ,  A61B5/0402 ,  A61B5/046 ,  A61B5/053 ,  A61B5/0836 ,  A61B5/087 ,  A61B5/4836 ,  A61B5/7207 ,  A61B5/721 ,  A61B5/742 ,  A61H31/00 ,  A61H31/005 ,  A61H2201/501 ,  A61H2201/5043 ,  A61H2201/5097 ,  A61H2230/045 ,  A61H2230/206 ,  A61H2230/208 ,  A61H2230/305 ,  A61H2230/505 ,  A61M16/0051 ,  A61M16/0057 ,  A61M16/0069 ,  A61M16/021 ,  A61N1/39 ,  A61N1/3925

Abstract: In embodiments, an external medical device is intended to care for a patient. If it receives an input that signifies that ventilation artifact is present in a signal of the patient, it transmits a corrective signal responsive to the received input. In further embodiments, a patient signal is received, which is generated from a patient while the patient is or was receiving chest compressions at a frequency Fc, and also receiving ventilations at frequency Fv. At least one filter mechanism may be applied to the patient signal to substantially remove artifacts at a) frequency Fc, b) a higher harmonic of frequency Fc, and c) a third frequency substantially equaling frequency Fc plus or minus frequency Fv, while substantially passing other frequencies between them. As a result, the patient signal can be cleaner, for diagnosing the patient's state more accurately.

Abstract translation: 在实施例中，外部医疗装置旨在照顾患者。 如果它接收到表示在患者的信号中存在通气伪像的输入，则响应于所接收的输入发送校正信号。 在另外的实施例中，接收患者信号，该患者信号在患者正在或正在以Fc频率接收胸部按压时从患者产生，并且还以频率Fv接收通气。 至少一个过滤器机构可以应用于患者信号，以基本上去除a）频率Fc，b）频率Fc的高次谐波，以及c）基本上等于频率Fc加或减频率Fv的第三频率，同时基本上通过 他们之间的其他频率。 因此，患者信号可以更清洁，更准确地诊断患者的状态。

公开(公告)号：US09591986B2

公开(公告)日：2017-03-14

申请号：US14539424

申请日：2014-11-12

Applicant: Cardiac Pacemakers, Inc.

Inventor： Barun Maskara ,  Pramodsingh Hirasingh Thakur ,  Qi An

IPC: A61N1/365 ,  A61B5/046 ,  A61B5/04 ,  A61N1/39 ,  A61N1/362

CPC classification number: A61B5/046 ,  A61B5/04012 ,  A61B5/0456 ,  A61B7/023 ,  A61N1/3624 ,  A61N1/36521 ,  A61N1/36585 ,  A61N1/36592 ,  A61N1/3925 ,  A61N1/3956 ,  A61N1/3987

Abstract: An apparatus may include a sensing circuit and an arrhythmia detection circuit. The sensing circuit is configured to generate a sensed physiological signal representative of cardiac activity of a subject. The arrhythmia detection circuit is configured to monitor ventricular depolarization (V-V) intervals using the sensed physiological signal, detect when at least a portion of the V-V intervals satisfies an arrhythmia detection threshold interval, calculate a value of variability of the V-V intervals and calculate a value of variability of a systolic portion of the V-V intervals in response to the detection, and generate an indication of atrial fibrillation (AF) according to a comparison including the value of variability of the V-V intervals and the value of variability of the systolic portion of the V-V intervals and provide the indication to at least one of a user or process.

Abstract translation: 装置可以包括感测电路和心律失常检测电路。 感测电路被配置为产生代表受试者的心脏活动的感测生理信号。 心律失常检测电路被配置为使用感测到的生理信号监测心室去极化（VV）间隔，检测当VV间隔的至少一部分满足心律失常检测阈值间隔时，计算VV间期的变异性值并计算值 响应于检测的VV间期的收缩部分的变异性，并且根据包括VV间期的变异性值和VV间期的收缩部分的变异性的值的比较来产生心房颤动（AF）的指示 VV间隔并且向至少一个用户或过程提供指示。

公开(公告)号：US09561005B2

公开(公告)日：2017-02-07

申请号：US15002521

申请日：2016-01-21

Applicant: Medtronic, Inc.

Inventor： Xusheng Zhang

IPC: A61B5/04 ,  A61B5/00 ,  A61B5/046 ,  A61B5/0464 ,  A61B5/0245

CPC classification number: A61B5/4836 ,  A61B5/0245 ,  A61B5/0422 ,  A61B5/04525 ,  A61B5/046 ,  A61B5/0464 ,  A61B5/686 ,  A61B5/7207 ,  A61N1/046 ,  A61N1/0563 ,  A61N1/3621 ,  A61N1/3962

Abstract: Techniques are described for generating beat templates and utilizing those beat templates to detect a cardiac event, e.g., a tachyarrhythmia. In particular, example methods and devices for acquiring qualified beats for template generation are described. Additionally, techniques are described for selecting subsets of the qualified beats to actually use in generating a beat template.

Abstract translation: 描述了用于产生拍子模板并利用那些拍子模板来检测心脏事件例如快速性心律失常的技术。 具体地，描述用于获取用于模板生成的合格节拍的示例性方法和设备。 另外，描述了用于选择合格节拍的子集以实际用于生成节拍模板的技术。

公开(公告)号：US20170027649A1

公开(公告)日：2017-02-02

申请号：US15304148

申请日：2015-04-09

Applicant: SIEMENS HEALTHCARE GMBH

Inventor： Atilla Peter Kiraly ,  Tommaso Mansi ,  Ali Kamen

IPC: A61B34/10 ,  A61B18/14 ,  A61B5/046 ,  A61B90/00 ,  G06F19/00 ,  A61B5/00

CPC classification number: A61B34/10 ,  A61B5/0037 ,  A61B5/0044 ,  A61B5/046 ,  A61B18/1492 ,  A61B90/37 ,  A61B2017/00053 ,  A61B2018/00351 ,  A61B2018/00839 ,  A61B2034/105 ,  A61B2090/374 ,  A61B2090/3762 ,  A61B2090/378 ,  G06F19/00 ,  G06F19/3481 ,  G16H50/50

Abstract: A method for guiding electrophysiology (EP) intervention using a patient-specific electrophysiology model includes acquiring a medical image of a patient subject (S201). Sparse EP signals are acquired over an anatomy using the medical image for guidance (S202). The sparse EP signals are interpolated using a patient specific computational electrophysiology model and a three-dimensional model of EP dynamics is generated therefrom (S203). A rendering of the three-dimensional model is displayed. Candidate intervention sites are received, effects on the EP dynamics resulting from intervention at the candidate intervention sites is simulated using the model, and a rendering of the model showing the simulated effects is displayed (S205).

Abstract translation: 使用患者特异性电生理学模型指导电生理学（EP）干预的方法包括获取患者对象的医学图像（S201）。 使用医学图像进行引导，在解剖结构上采集稀疏EP信号（S202）。 使用患者特定的计算电生理学模型对稀疏的EP信号进行内插，并从其生成EP动态的三维模型（S203）。 显示三维模型的渲染。 接收候选干预站点，使用模型模拟对候选干预站点干预造成的EP动态影响，并显示显示模拟效果的模型的渲染（S205）。

公开(公告)号：US09549684B2

公开(公告)日：2017-01-24

申请号：US14965388

申请日：2015-12-10

Applicant: The Regents of the University of California ,  Topera, Inc.

Inventor： Sanjiv Narayan ,  Ruchir Sehra

IPC: A61B5/046 ,  A61B5/0452 ,  A61B5/0456 ,  A61B5/042 ,  A61B5/0472 ,  A61B5/0464 ,  A61B5/04 ,  A61B5/0255 ,  A61B5/0432 ,  A61B5/044 ,  A61B5/00

CPC classification number: A61B5/0452 ,  A61B5/0255 ,  A61B5/04011 ,  A61B5/04012 ,  A61B5/0422 ,  A61B5/0432 ,  A61B5/044 ,  A61B5/0456 ,  A61B5/046 ,  A61B5/0464 ,  A61B5/0472 ,  A61B5/4857 ,  A61B5/6852 ,  A61B5/7221 ,  A61B5/726 ,  A61B5/7264 ,  A61B5/7278

Abstract: Reconstruction of cardiac information representing a complex rhythm disorder is facilitated by assigning activation onsets to non-discernible beats in low confidence signals based upon time associations relative to activation onsets in adjacent high confidence signals.

Abstract translation: 通过基于相邻相邻高置信度信号中的激活onsets的时间关联，将激活onsets分配给低置信度信号中的不可辨别的节拍，便于重建表示复杂节律紊乱的心脏信息。

公开(公告)号：US20170010469A1

公开(公告)日：2017-01-12

申请号：US15269667

申请日：2016-09-19

Applicant: MAGIC LEAP, INC.

Inventor： Nicole Elizabeth Samec ,  John Graham Macnamara ,  Christopher M. Harrises ,  Brian T. Schowengerdt ,  Rony Abovitz ,  Mark Baerenrodt

IPC: G02B27/01 ,  G06T11/00 ,  G06T3/40 ,  G02B27/00

CPC classification number: G02B27/0172 ,  A61B3/0008 ,  A61B3/022 ,  A61B3/024 ,  A61B3/028 ,  A61B3/063 ,  A61B3/066 ,  A61B3/08 ,  A61B3/085 ,  A61B3/10 ,  A61B3/1015 ,  A61B3/102 ,  A61B3/1035 ,  A61B3/113 ,  A61B3/12 ,  A61B3/1216 ,  A61B3/13 ,  A61B3/14 ,  A61B3/165 ,  A61B5/0059 ,  A61B5/0066 ,  A61B5/0077 ,  A61B5/01 ,  A61B5/046 ,  A61B5/0476 ,  A61B5/0496 ,  A61B5/14532 ,  A61B5/1455 ,  A61B5/14555 ,  A61B5/6803 ,  A61B8/10 ,  A61B8/461 ,  A61B2562/0204 ,  A61B2562/0219 ,  A61B2562/0247 ,  A61F9/0026 ,  A61F2007/0004 ,  A61F2007/004 ,  A61F2009/00863 ,  A61H2201/165 ,  A61M21/02 ,  A61M2021/0022 ,  A61M2021/0027 ,  A61M2021/0066 ,  A61M2205/3375 ,  A61M2205/507 ,  A61N2005/0648 ,  G02B21/0032 ,  G02B27/0093 ,  G02B27/0179 ,  G02B2027/0138 ,  G02B2027/014 ,  G02B2027/0185 ,  G02C7/027 ,  G06T19/006 ,  G06T2207/10024 ,  G06T2207/10148 ,  G06T2207/10152 ,  G06T2207/30041 ,  G16H40/63 ,  G16H40/67

Abstract: Configurations are disclosed for a health system to be used in various healthcare applications, e.g., for patient diagnostics, monitoring, and/or therapy. The health system may comprise a light generation module to transmit light or an image to a user, one or more sensors to detect a physiological parameter of the user's body, including their eyes, and processing circuitry to analyze an input received in response to the presented images to determine one or more health conditions or defects.

Abstract translation: 公开了用于健康系统的配置，以用于各种保健应用，例如用于患者诊断，监测和/或治疗。 卫生系统可以包括用于向用户传输光或图像的光生成模块，用于检测包括他们的眼睛的用户身体的生理参数的一个或多个传感器，以及响应于所呈现的接收到的输入来分析输入的处理电路 图像确定一个或多个健康状况或缺陷。