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    COMPOSITIONS AND TECHNIQUES FOR VAGINAL INSERTION
    38.
    发明公开
    COMPOSITIONS AND TECHNIQUES FOR VAGINAL INSERTION 审中-公开

    公开(公告)号：US20240189265A1

    公开(公告)日：2024-06-13

    申请号：US18292097

    申请日：2022-07-25

    申请人： Daré Bioscience, Inc.

    发明人： David Friend ,  Jennifer Kiang ,  Nicolas J. Pacelli ,  Mark Walters

    IPC分类号： A61K31/196 ,  A61K9/00 ,  A61K9/06 ,  A61K31/5575 ,  A61K47/10 ,  A61K47/12 ,  A61K47/34 ,  A61K47/36

    CPC分类号： A61K31/196 ,  A61K9/0034 ,  A61K9/06 ,  A61K31/5575 ,  A61K47/10 ,  A61K47/12 ,  A61K47/34 ,  A61K47/36

    摘要： The present disclosure generally relates to compositions and techniques for vaginal insertion. In some embodiments, a composition such as a gel may be applied to the vagina of a subject that is relatively viscous, for example, with a viscosity at room temperature of at least 1.5 million cP. The composition may also contain an active ingredient, e.g., dinoprostone, diclofenac, and/or salts thereof. Compositions having such relatively high viscosities may be useful, for example, to prevent the composition from readily exiting the vagina or degrading too quickly. This may, for example, allow the composition to release the active ingredient over a relatively long period of time to the vagina. In some embodiments, such compositions may be prepared by removing air from the composition to increase its viscosity or cause the composition to form a gel, etc. In addition, certain embodiments as described herein are generally directed to techniques for making or using such compositions, kits including such compositions, or the like.