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1.发明申请公开(公告)号：US20230119714A1
公开(公告)日：2023-04-20
申请号：US17990979
申请日：2022-11-21
发明人： Derek John LONDESBROUGH , Christopher BROWN , Julian Scott NORTHEN , Gillian MOORE , Hemant Kashinath PATIL , David E. NICHOLS
摘要： This invention relates to the large-scale production of psilocybin for use in medicine. More particularly, it relates to a method of obtaining high purity crystalline psilocybin, particularly, in the form of Polymorph A. It further relates to a method for the manufacture of psilocybin and intermediates in the production thereof and formulations containing psilocybin.
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2.发明公开公开(公告)号：US20230250115A1
公开(公告)日：2023-08-10
申请号：US18135265
申请日：2023-04-17
发明人： Derek John LONDESBROUGH , Christopher BROWN , Julian Scott NORTHEN , Gillian MOORE , Hemant Kashinath PATIL , David E. NICHOLS
CPC分类号： C07F9/5728 , C07D209/16 , A61K9/2054 , A61K9/0053 , A61K47/36 , A61K47/38 , C07B2200/13
摘要： This invention relates to the large-scale production of psilocybin for use in medicine. More particularly, it relates to a method of obtaining high purity crystalline psilocybin, particularly, in the form of Polymorph A. It further relates to a method for the manufacture of psilocybin and intermediates in the production thereof and formulations containing psilocybin.
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3.发明申请公开(公告)号：US20210087212A1
公开(公告)日：2021-03-25
申请号：US17116739
申请日：2020-12-09
发明人： Derek John LONDESBROUGH , Christopher BROWN , Julian Scott NORTHEN , Gillian MOORE , Hemant Kashinath PATIL , David E. NICHOLS
摘要： This invention relates to the large-scale production of psilocybin for use in medicine. More particularly, it relates to a method of obtaining high purity crystalline psilocybin, particularly, in the form of Polymorph A. It further relates to a method for the manufacture of psilocybin and intermediates in the production thereof and formulations containing psilocybin.
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4.发明公开公开(公告)号：US20240360162A1
公开(公告)日：2024-10-31
申请号：US18767494
申请日：2024-07-09
发明人： Derek John LONDESBROUGH , Christopher BROWN , Julian Scott NORTHEN , Gillian MOORE , Hemant Kashinath PATIL , David E. NICHOLS
CPC分类号： C07F9/5728 , A61K9/0053 , A61K9/2054 , A61K47/36 , A61K47/38 , C07D209/16 , C07B2200/13
摘要： This invention relates to the large-scale production of psilocybin for use in medicine. More particularly, it relates to a method of obtaining high purity crystalline psilocybin, particularly, in the form of Polymorph A. It further relates to a method for the manufacture of psilocybin and intermediates in the production thereof and formulations containing psilocybin.
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5.发明公开公开(公告)号：US20240252521A1
公开(公告)日：2024-08-01
申请号：US18522440
申请日：2023-11-29
发明人： Derek John LONDESBROUGH , Christopher BROWN , Julian Scott NORTHEN , Gillian MOORE , Hemant Kashinath PATIL , David E. NICHOLS , Megan CROAL , Hans Åke ERIKSSON , George GOLDSMITH , Molly Tabitha HICKEY , Shaun HURLEY , Ekaterina MALIEVSKAIA , Lindsey MARWOOD , Drummond E-Wen Joe MCCULLOCH , Laurie Emma MEDHURST , Nathan POULSEN , Aslihan SELIMBEYOGLU , Anaïs SOULA , Amanda Tan SHUXIANG , Manon Cecile Elisabeth VERAART , Tobias Patrick WHELAN , Lars Christian WILDE , Stephen WRIGHT
IPC分类号： A61K31/675 , A61K9/00 , A61K9/20 , A61K9/48 , A61K31/661 , A61P25/00 , A61P25/04 , A61P25/08 , A61P25/16 , A61P25/20 , A61P25/22 , A61P25/24 , A61P25/28 , C07F9/572
CPC分类号： A61K31/675 , A61K9/0053 , A61K9/20 , A61K9/48 , A61K31/661 , A61P25/00 , A61P25/04 , A61P25/08 , A61P25/16 , A61P25/20 , A61P25/22 , A61P25/24 , A61P25/28 , C07F9/5728 , C07B2200/13
摘要： The disclosure provides methods for treating a subject in need thereof comprising administering to the subject a therapeutically-effective dose of psilocybin. The methods described herein may be used to treat a variety of diseases, disorders, and conditions. For example, the methods may be used to treat anxiety disorders, eating disorders, and headache disorders.
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6.发明公开公开(公告)号：US20240199660A1
公开(公告)日：2024-06-20
申请号：US18433051
申请日：2024-02-05
发明人： Derek John LONDESBROUGH , Christopher BROWN , Julian Scott NORTHEN , Gillian MOORE , Hemant Kashinath PATIL , David E. NICHOLS
CPC分类号： C07F9/5728 , A61K9/0053 , A61K9/2054 , A61K47/36 , A61K47/38 , C07D209/16 , C07B2200/13
摘要： This invention relates to the large-scale production of psilocybin for use in medicine. More particularly, it relates to a method of obtaining high purity crystalline psilocybin, particularly, in the form of Polymorph A. It further relates to a method for the manufacture of psilocybin and intermediates in the production thereof and formulations containing psilocybin.
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7.发明公开公开(公告)号：US20230330117A1
公开(公告)日：2023-10-19
申请号：US18210526
申请日：2023-06-15
发明人： Derek John LONDESBROUGH , Christopher BROWN , Julian Scott NORTHEN , Gillian MOORE , Hemant Kashinath PATIL , David E. NICHOLS , Megan CROAL , Hans Åke ERIKSSON , George GOLDSMITH , Molly Tabitha HICKEY , Shaun HURLEY , Ekaterina MALIEVSKAIA , Lindsey MARWOOD , Drummond E-Wen Joe MCCULLOCH , Laurie Emma MEDHURST , Nathan POULSEN , Aslihan SELIMBEYOGLU , Anaïs SOULA , Amanda Tan SHUXIANG , Manon Cecile Elisabeth VERAART , Tobias Patrick WHELAN , Lars Christian WILDE , Stephen WRIGHT
IPC分类号： A61K31/675 , A61P25/00 , A61P25/20 , A61P25/28 , A61P25/22 , A61P25/04 , A61P25/08 , A61P25/16 , C07F9/572 , A61K9/00 , A61K9/20 , A61K9/48 , A61K31/661 , A61P25/24
CPC分类号： A61K31/675 , A61P25/00 , A61P25/20 , A61P25/28 , A61P25/22 , A61P25/04 , A61P25/08 , A61P25/16 , C07F9/5728 , A61K9/0053 , A61K9/20 , A61K9/48 , A61K31/661 , A61P25/24 , C07B2200/13
摘要： The disclosure provides methods for treating a subject in need thereof comprising administering to the subject a therapeutically-effective dose of psilocybin. The methods described herein may be used to treat a variety of diseases, disorders, and conditions. For example, the methods may be used to treat anxiety disorders, eating disorders, and headache disorders.
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公开(公告)号：US20230023092A1
公开(公告)日：2023-01-26
申请号：US17604610
申请日：2020-04-17
发明人： Derek John LONDESBROUGH , Christopher BROWN , Julian Scott NORTHEN , Gillian MOORE , Hemant Kashinath PATIL , David E. NICHOLS , Megan CROAL , Hans Ake ERIKSSON , George GOLDSMITH , Molly Tabitha HICKEY , Shaun HURLEY , Ekaterina MALIEVSKAIA , Lindsey MARWOOD , Drummond E-Wen Joe MCCULLOCH , Laurie Emma MEDHURST , Nathan POULSEN , Aslihan SELIMBEYOGLU , Anais SOULA , Amanda Tan SHUXIANG , Manon Cecile Elisabeth VERAART , Tobias Patrick WHELAN , Lars Christian WILDE , Stephen WRIGHT
摘要： The disclosure provides methods for treating a subject in need thereof comprising administering to the subject a therapeutically-effective dose of psilocybin. The methods described herein may be used to treat a variety of diseases, disorders, and conditions. For example, the methods may be used to treat depression, neurocognitive disorders, autism spectrum disorder, and/or attention-deficit/hyperactivity disorder.
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9.发明申请公开(公告)号：US20220088041A1
公开(公告)日：2022-03-24
申请号：US17540962
申请日：2021-12-02
发明人： Derek John LONDESBROUGH , Christopher BROWN , Julian Scott NORTHEN , Gillian MOORE , Hemant Kashinath PATIL , David E. NICHOLS , Megan CROAL , Hans Åke ERIKSSON , George GOLDSMITH , Molly Tabitha HICKEY , Shaun HURLEY , Ekaterina MALIEVSKAIA , Lindsey MARWOOD , Drummond E-Wen Joe MCCULLOCH , Laurie Emma MEDHURST , Nathan POULSEN , Aslihan SELIMBEYOGLU , Anaïs SOULA , Amanda Tan SHUXIANG , Manon Cecile Elisabeth VERAART , Tobias Patrick WHELAN , Lars Christian WILDE , Stephen WRIGHT
IPC分类号： A61K31/675 , A61P25/00
摘要： The disclosure provides methods for treating a subject in need thereof comprising administering to the subject a therapeutically-effective dose of psilocybin. The methods described herein may be used to treat a variety of diseases, disorders, and conditions. For example, the methods may be used to treat anxiety disorders, eating disorders, and headache disorders.
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10.发明申请公开(公告)号：US20220402949A1
公开(公告)日：2022-12-22
申请号：US17886204
申请日：2022-08-11
发明人： Derek John LONDESBROUGH , Christopher BROWN , Julian Scott NORTHEN , Gillian MOORE , Hemant Kashinath PATIL , David E. NICHOLS
摘要： This invention relates to the large-scale production of psilocybin for use in medicine. More particularly, it relates to a method of obtaining high purity crystalline psilocybin, particularly, in the form of Polymorph A. It further relates to a method for the manufacture of psilocybin and intermediates in the production thereof and formulations containing psilocybin.
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