公开(公告)号：US5455232A

公开(公告)日：1995-10-03

申请号：US224070

申请日：1994-04-07

申请人： Goran Piljac ,  Visnja Piljac

发明人： Goran Piljac ,  Visnja Piljac

IPC分类号： C07H15/04 ,  A61K8/00 ,  A61K8/60 ,  A61K31/70 ,  A61K31/7028 ,  A61P17/00 ,  A61P17/02 ,  A61P17/04 ,  A61P17/08 ,  A61P29/00 ,  A61P31/22 ,  A61P37/00 ,  A61P37/08 ,  A61Q19/00 ,  C12P19/12 ,  C12P19/44 ,  A61K31/715

CPC分类号： A61K8/602 ,  A61K31/70 ,  A61K31/7028 ,  A61Q19/00 ,  C12P19/44 ,  Y10S514/844 ,  Y10S514/845 ,  Y10S514/846 ,  Y10S514/847 ,  Y10S514/848 ,  Y10S514/858 ,  Y10S514/859 ,  Y10S514/86 ,  Y10S514/861 ,  Y10S514/862 ,  Y10S514/863 ,  Y10S514/864 ,  Y10S514/865

摘要： The invention relates to a pharmaceutical preparation comprising as an active ingredient at least one rhamnolipid or a pharmaceutically acceptable salt thereof, and a carrier and/or diluent, preferably comprising a rhamnolipid of the general formula: ##STR1## wherein R.sub.1 =H, alpha-L-rhamnopyranosyl; ##STR2## R.sub.3 =(C.sub.5 -C.sub.20)-saturated, -mono- of poly-unsaturated alkyl; R.sub.4 =(C.sub.5 -C.sub.20)-saturated, -mono- of poly-unsaturated alkyl;

摘要翻译： 本发明涉及一种药物制剂，其包含作为活性成分的至少一种鼠李糖脂或其药学上可接受的盐，以及载体和/或稀释剂，优选包含通式为的鼠李糖脂。 R 3 =（C 5 -C 20）饱和的单 - 多 - 不饱和烷基; R4 =（C5-C20）饱和一元多 - 不饱和烷基;

公开(公告)号：US5435997A

公开(公告)日：1995-07-25

申请号：US193435

申请日：1994-02-08

申请人： Michael J. Burns

发明人： Michael J. Burns

IPC分类号： A61K8/38 ,  A61K8/92 ,  A61K8/97 ,  A61K31/00 ,  A61K33/40 ,  A61K36/00 ,  A61K36/54 ,  A61K36/886 ,  A61Q9/02 ,  A61Q19/00 ,  A61K7/13 ,  A61K31/125 ,  A61K35/78

CPC分类号： A61Q9/02 ,  A61K36/886 ,  A61K8/38 ,  A61K8/922 ,  A61K8/97 ,  A61Q19/002 ,  Y10S424/05 ,  Y10S514/828 ,  Y10S514/844 ,  Y10S514/848 ,  Y10S514/859 ,  Y10S514/861 ,  Y10S514/88 ,  Y10S514/886 ,  Y10S514/944 ,  Y10S514/964

摘要： A topical agent and method for the treatment and prevention of pseudofolliculitis barbae, related secondary bacterial infections and other skin conditions associated with shaving result from a combination of three ingredients, namely benzoyl peroxide, camphor oil and aloe vera present in 15:4:1 parts by volume of the composition, respectively.

摘要翻译： 用于治疗和预防假性果皮炎，相关的继发性细菌感染和与剃刮相关的其它皮肤病症的局部药剂和方法，由三份成分组合，即15：4：1份中存在的过氧化苯甲酰，樟脑油和芦荟 分别为体积的组合物。

公开(公告)号：US5348735A

公开(公告)日：1994-09-20

申请号：US76422

申请日：1993-06-14

申请人： Dennis Harris ,  Ronald General

发明人： Dennis Harris ,  Ronald General

IPC分类号： A61K8/02 ,  A61K8/26 ,  A61K8/34 ,  A61K33/06 ,  A61Q15/00 ,  A61K7/32 ,  A61K7/38

CPC分类号： A61Q15/00 ,  A61K8/0295 ,  A61K8/26 ,  A61K8/347 ,  Y10S514/848 ,  Y10S514/946

摘要： A liquid crystal deodorant is produced by dissolving a powdered crystalline double sulfate of aluminum (alum) in a saturated solution of water, or a combination of water and alcohol, preferably denatured ethanol. The deodorant then is applied in any suitable fashion to provide odor control, particularly for underarm and foot odor control purposes.

摘要翻译： 通过将铝（明矾）的粉末结晶双硫酸盐溶解在饱和的水溶液或水和醇的组合中，优选变性乙醇来制备液晶除臭剂。 然后以任何合适的方式施用除臭剂以提供气味控制，特别是用于腋下和脚部气味控制目的。

公开(公告)号：US5294444A

公开(公告)日：1994-03-15

申请号：US796685

申请日：1991-11-25

申请人： Mami Nakamura ,  Seiji Honma

发明人： Mami Nakamura ,  Seiji Honma

IPC分类号： A61K8/30 ,  A61K8/00 ,  A61K8/02 ,  A61K8/06 ,  A61K8/39 ,  A61K8/55 ,  A61K8/68 ,  A61Q19/00 ,  A61K7/06 ,  A61K7/09 ,  A61K7/11 ,  A61K31/74

CPC分类号： A61K8/068 ,  A61K8/39 ,  A61K8/556 ,  A61K8/68 ,  A61Q19/00 ,  A61K2800/262 ,  A61K2800/75 ,  Y10S514/844 ,  Y10S514/845 ,  Y10S514/846 ,  Y10S514/847 ,  Y10S514/848

摘要： A cosmetic composition is provided comprising (A) 0.05-30% by weight of an amphiphatic lipid, (B) 0.05-30% by weight of a nonionic surfactant, (C) 1-50% by weight, based on (b), of an ionic surfactant, and (D) 40-99% by weight of an aqueous medium, wherein said composition is transparent or semi-transparent, and wherein the ratio of (A)/[(B)+(C)] is 0.2-10, which is beautifully transparent or semi-transparent, and in which the amphiphatic lipids are stably microdispersed.

摘要翻译： 提供了一种化妆品组合物，其包含（A）0.05-30重量％的脂族脂质，（B）0.05-30重量％的非离子表面活性剂，（C）1-50重量％，基于（b）， 的离子表面活性剂，和（D）40-99重量％的水性介质，其中所述组合物是透明或半透明的，并且其中（A）/（（B）+（C））的比率为0.2 -10，其是透明或半透明的，并且其中两性脂质稳定地微分散。

公开(公告)号：US5213799A

公开(公告)日：1993-05-25

申请号：US802549

申请日：1991-12-05

申请人： Stefan M. Goring ,  Claudia Koss

发明人： Stefan M. Goring ,  Claudia Koss

IPC分类号： A61K8/30 ,  A61K8/00 ,  A61K8/03 ,  A61K8/37 ,  A61K8/39 ,  A61Q5/00 ,  A61Q19/00

CPC分类号： A61K8/03 ,  A61K8/39 ,  A61Q19/00 ,  Y10S514/844 ,  Y10S514/845 ,  Y10S514/846 ,  Y10S514/847 ,  Y10S514/848 ,  Y10S514/938 ,  Y10S514/943

摘要： This invention refers to cosmetic compositions, particularly a skin treating preparation, comprising a transparent oil phase and a transparent aqueous phase, preferably with humectant effect, which permits a homogeneous mixture when being shaken, and which separates again in two transparent phases thereafter. These properties are achieved by the addition of 0.1 to 1.0% by weight of a C.sub.12 -C.sub.18 fatty acid triglycerol ester.

公开(公告)号：US5179127A

公开(公告)日：1993-01-12

申请号：US842296

申请日：1992-02-26

申请人： Adam C. Hsu

发明人： Adam C. Hsu

IPC分类号： A01N37/28 ,  A01N47/24 ,  C07C281/04

CPC分类号： A01N37/28 ,  A01N47/24 ,  C07C281/04 ,  Y10S514/845 ,  Y10S514/846 ,  Y10S514/847 ,  Y10S514/848

摘要： Compounds of the formula ##STR1## wherein A is selected from the group consisting of (1) phenyl, (2) naphthyl, (3) phenyl substituted with one or more halo, cyano, (C.sub.1 -C.sub.4)alkyl, nitro, (C.sub.1 -C.sub.4)haloalkyl, and (C.sub.1 -C.sub.4)thioalkyl, (4) naphthyl substituted with one or more halo, cyano, (C.sub.1 -C.sub.4) alkyl, nitro, (C.sub.1 -C.sub.4)haloalkyl, and (C.sub.1 -C.sub.4)thioalkyl, (5) thiophene, (6) furan, (7) thiophene substituted with one or more substituents selected from halo and nitro, and (8) furan substituted with one or more substituents selected from halo and nitro;R is selected from the group consisting of hydrogen, (C.sub.1 -C.sub.4)alkyl and substituted or unsubstituted phenyl wherein the substituents are selected from one or more halo, cyano, (C.sub.1 -C.sub.4)alkyl, nitro, (C.sub.1 -C.sub.4) haloalkyl, and (C.sub.1 -C.sub.4)thioalkyl andR.sup.1 is selected from the group consisting of (C.sub.1 -C.sub.4) alkoxy; hydrogen; optionally substituted phenyl wherein the phenyl substituents are selected from the group consisting of halo, cyano, (C.sub.1 -C.sub.4)alkyl; nitro, (C.sub.1 -C.sub.4)haloalkyl, and (C.sub.1 -C.sub.4)thioalkyl; (C.sub.1 -C.sub.8) alkyl; and optionally substituted heterocycles wherein said heterocycles are selected from the group consisting of thiophene, furan, imidazole, and triazole, which are optionally substituted with (C.sub.1 -C.sub.3)alkyl, halo, and nitro; andX is selected from the group consisting of I and Br.the halopropargyl acyl hydrazone compounds of the invention are active microbicides and can be used to control microorganisms.

摘要翻译： 其中A选自（1）苯基，（2）萘基，（3）被一个或多个卤素，氰基，（C 1 -C 4）烷基，硝基，（C 1 -C 4）烷基取代的苯基的式 -C 1-4）卤代烷基，（C 1 -C 4）卤代烷基，（4）被一个或多个卤素，氰基，（C 1 -C 4）烷基，硝基，（C 1 -C 4）卤代烷基和（C 1 -C 4） （5）噻吩，（6）呋喃，（7）被一个或多个选自卤素和硝基的取代基取代的噻吩，和（8）被一个或多个选自卤素和硝基的取代基取代的呋喃; R选自氢，（C 1 -C 4）烷基和取代或未取代的苯基，其中取代基选自一个或多个卤素，氰基，（C 1 -C 4）烷基，硝基，（C 1 -C 4）卤代烷基， 和（C 1 -C 4）硫代烷基，R 1选自（C 1 -C 4）烷氧基; 氢; 任选取代的苯基，其中苯基取代基选自卤素，氰基，（C 1 -C 4）烷基; 硝基，（C 1 -C 4）卤代烷基和（C 1 -C 4）硫代烷基; （C1-C8）烷基; 和任选取代的杂环，其中所述杂环选自噻吩，呋喃，咪唑和三唑，其任选被（C 1 -C 3）烷基，卤素和硝基取代; X选自I和Br。 本发明的卤代炔丙基酰腙化合物是活性杀微生物剂，可用于控制微生物。

公开(公告)号：US5071640A

公开(公告)日：1991-12-10

申请号：US306629

申请日：1989-02-06

申请人： Guy Vanlerberghe ,  Henri Sebag

发明人： Guy Vanlerberghe ,  Henri Sebag

IPC分类号： C11D1/72 ,  A61K8/00 ,  A61K8/14 ,  A61K8/39 ,  A61K8/46 ,  A61K8/72 ,  A61K8/86 ,  A61K47/08 ,  A61K47/20 ,  A61Q1/00 ,  A61Q1/02 ,  A61Q1/12 ,  A61Q5/00 ,  A61Q19/00 ,  A61Q19/10 ,  B01F17/42 ,  B01J23/04 ,  B01J27/10 ,  B01J27/12 ,  B01J31/02 ,  C07B61/00 ,  C07C41/00 ,  C07C41/02 ,  C07C41/03 ,  C07C43/10 ,  C07C43/11 ,  C07C43/14 ,  C07C43/178 ,  C07C67/00 ,  C07C313/00 ,  C07C315/04 ,  C07C317/18 ,  C07C319/14 ,  C07C323/12 ,  C08G65/26 ,  C08G65/28 ,  C08G65/329

CPC分类号： C08G65/329 ,  A61K8/14 ,  A61K8/86 ,  A61Q19/00 ,  A61Q5/00 ,  A61Q5/12 ,  C07C41/03 ,  C08G65/2636 ,  A61Q1/02 ,  A61Q1/14 ,  A61Q19/007 ,  Y10S424/05 ,  Y10S514/844 ,  Y10S514/845 ,  Y10S514/846 ,  Y10S514/847 ,  Y10S514/848 ,  Y10S514/852 ,  Y10S514/864 ,  Y10S514/88 ,  Y10S514/938

摘要： Non-ionic products of the formula:R--X--[C.sub.2 H.sub.3 (OCH.sub.2 CH.sub.2).sub.n(OH)--CH.sub.2 --Y--R'in which R and R' denote alkyl or alkenyl radicals having from 6 to 20 carbon atoms, the sum of the numbers of carbon atoms in R and R' being 24 to 32; X denotes an oxygen atom, a sulphur atom or a sulphoxide group; Y denotes a sulphur atom, a sulphoxide group or a methylene group (if Y denotes methylene, the sum of the numbers of carbon atoms in R and R' is 22 to 30); and n denotes an integer or decimal number from 1 to 40 are disclosed. These non-ionic compounds are suitable for use in pharmaceutical or cosmetic applications, in particular for the care of the skin or hair.

公开(公告)号：US5034221A

公开(公告)日：1991-07-23

申请号：US369938

申请日：1989-06-22

申请人： Steven E. Rosen ,  Robert M. Thomas

发明人： Steven E. Rosen ,  Robert M. Thomas

IPC分类号： A61K8/37 ,  A61K8/73 ,  A61K8/97 ,  A61Q9/02

CPC分类号： A61K8/732 ,  A61K8/37 ,  A61K8/97 ,  A61Q9/02 ,  Y10S514/848 ,  Y10S514/859 ,  Y10S514/88

摘要： A topical agent and method for the treatment and prevention of pseudofolliculitis barbae, commonly known as "razor bumps", is effected by the topical application to beard areas of the face of a combination of acetylsalicylic acid, corn starch, isopropyl alcohol, and aloe vera.

摘要翻译： 用于治疗和预防假性扁桃体炎的局部药剂和方法，通常称为“剃刀隆起”，通过局部施用于乙酰水杨酸，玉米淀粉，异丙醇和芦荟组合的面部的胡须区域 。

公开(公告)号：US5002974A

公开(公告)日：1991-03-26

申请号：US176897

申请日：1988-04-04

申请人： Navin M. Geria

发明人： Navin M. Geria

IPC分类号： A61K8/00 ,  A61K8/25 ,  A61K8/31 ,  A61K8/37 ,  A61K8/39 ,  A61K8/41 ,  A61K8/42 ,  A61K8/49 ,  A61K8/63 ,  A61K8/65 ,  A61K8/73 ,  A61K8/81 ,  A61K8/86 ,  A61K8/89 ,  A61K8/891 ,  A61K8/92 ,  A61K8/97 ,  A61K8/98 ,  A61K9/00 ,  A61K31/16 ,  A61K31/535 ,  A61K36/47 ,  A61K47/00 ,  A61K47/44 ,  A61Q19/00 ,  A61Q19/10 ,  C08L83/04

CPC分类号： A61K9/0014 ,  A61K31/535 ,  A61K8/39 ,  A61K8/63 ,  A61K8/8147 ,  A61K8/86 ,  A61K8/92 ,  A61Q19/00 ,  Y10S514/817 ,  Y10S514/844 ,  Y10S514/845 ,  Y10S514/846 ,  Y10S514/847 ,  Y10S514/848 ,  Y10S514/938 ,  Y10S514/939 ,  Y10S514/941 ,  Y10S514/943

摘要： A long lasting, esthetically pleasing medicated skin care moisturizing composition comprising(1) an oil phase comprising oil from about 30% to about 80% and a non-ionic surface active agent having an HLB number of about 7 to about 12, wherein the non-ionic surface active agent is present in an amount of about 5% to about 9%;(2) an aqueous phase comprising an aqueous thickening agent from about 0.05% to about 5% and water from about 15% to about 65%;(3) an effective amount of a topical medicament; wherein the oil phase is added to the aqueous phase to form an emulsion and a topical medicament admixed into the emulsion has been developed.The method of preparation of the composition and a method of treating skin with the composition are also disclosed.

公开(公告)号：US4992476A

公开(公告)日：1991-02-12

申请号：US176907

申请日：1988-04-04

申请人： Navin M. Geria

发明人： Navin M. Geria

IPC分类号： A61K8/00 ,  A61K8/25 ,  A61K8/26 ,  A61K8/31 ,  A61K8/37 ,  A61K8/39 ,  A61K8/41 ,  A61K8/42 ,  A61K8/65 ,  A61K8/73 ,  A61K8/81 ,  A61K8/86 ,  A61K8/89 ,  A61K8/891 ,  A61K8/92 ,  A61K8/97 ,  A61K8/98 ,  A61K36/47 ,  A61Q17/00 ,  A61Q19/00 ,  A61Q19/10 ,  C08L83/04

CPC分类号： A61K8/86 ,  A61K8/26 ,  A61K8/39 ,  A61K8/8111 ,  A61K8/8147 ,  A61K8/92 ,  A61Q19/00 ,  A61Q19/10 ,  A61K2800/28 ,  Y10S514/817 ,  Y10S514/844 ,  Y10S514/845 ,  Y10S514/846 ,  Y10S514/847 ,  Y10S514/848 ,  Y10S514/938 ,  Y10S514/939 ,  Y10S514/941 ,  Y10S514/943

摘要： A long lasting, esthetically pleasing skin cleansing and care moisturizing composition comprising(1) an oil phase comprising oil from about 30% to about 80% and a non-ionic surface active agent having an HLB number of about 7 to about 12, wherein the non-ionic surface active agent is present in an amount of about 5% to about 9%;(2) an aqueous phase comprising an aqueous thickening agent from about 0.05% to about 5% and water from about 15% to about 65% wherein the oil phase is added to the aqueous phase to form an emulsion has been developed,(3) an effective amount of an abrasive to remove oily deposits, cosmetics and particulates from the skin surface.The method of preparation of the composition and a method of treating skin with the composition are also disclosed.