公开(公告)号：US12121601B2

公开(公告)日：2024-10-22

申请号：US17614548

申请日：2021-02-04

Applicant: SHANGHAI JIAO TONG UNIVERSITY

Inventor： Guangyin Yuan ,  Wenjiang Ding ,  Yueling Li ,  Li Shen ,  Jianxiong Yuan

IPC: A61K8/19 ,  A61K8/25 ,  A61K8/34 ,  A61K8/46 ,  A61K8/73 ,  A61K8/81 ,  A61K8/9789 ,  A61K33/06 ,  A61P1/02 ,  A61Q11/00

CPC classification number: A61K8/19 ,  A61K8/25 ,  A61K8/345 ,  A61K8/463 ,  A61K8/73 ,  A61K8/731 ,  A61K8/8176 ,  A61K8/9789 ,  A61K33/06 ,  A61P1/02 ,  A61Q11/00 ,  A61K2800/28 ,  A61K2800/412 ,  A61K2800/75

Abstract: The-use of magnesium hydride in the preparation of a composition for preventing and treating chronic periodontitis, and a magnesium hydride toothpaste are provided. In the composition or the magnesium hydride toothpaste, magnesium hydride has a weight percentage of 1% to 3%. The toothpaste has the functions of disinfection, anti-inflammation, anti-oxidation, removing tooth stains, improving bad breath, alleviating gingival swelling, bleeding, and recession, and improving periodontitis symptoms. An appropriate amount of magnesium hydride fine particles is added in toothpaste, and the magnesium hydride particles can be hydrolyzed into hydrogen and magnesium ions with anti-inflammatory effects, which can also inhibit alveolar bone resorption. The magnesium hydride-containing composition is safe in use, and can effectively prevent the occurrence and development of periodontal diseases after long-term use.

公开(公告)号：US20190184065A1

公开(公告)日：2019-06-20

申请号：US16282598

申请日：2019-02-22

Applicant: Teoxane

Inventor： FRANCOIS BOURDON ,  Stephane Meunier

IPC: A61L27/54 ,  A61K47/02 ,  A61Q19/08 ,  A61K31/728 ,  A61K31/16 ,  A61K8/49 ,  A61K31/167 ,  A61L27/20 ,  A61L27/12 ,  A61K9/00 ,  A61K8/24 ,  A61K8/73 ,  A61K31/445 ,  A61K31/451

CPC classification number: A61L27/54 ,  A61K8/24 ,  A61K8/4926 ,  A61K8/735 ,  A61K9/0019 ,  A61K9/0024 ,  A61K31/16 ,  A61K31/167 ,  A61K31/445 ,  A61K31/451 ,  A61K31/728 ,  A61K47/02 ,  A61K2800/524 ,  A61K2800/75 ,  A61K2800/91 ,  A61L27/12 ,  A61L27/20 ,  A61L2300/204 ,  A61L2300/402 ,  A61L2400/06 ,  A61Q19/08 ,  A61K2300/00

Abstract: A sterile composition for intraepidermal, intradermal, and/or subcutaneous administration including an effective amount of hyaluronic acid or a salt thereof, the effective amount of hyaluronic acid or salt thereof ranging from 1 to 3 wt % of the overall weight of the sterile composition, mepivacaine or a salt thereof as a first anesthetic agent at a concentration ranging from 0.05 to 3 wt % of an overall weight of the sterile composition, and a balanced salt solution in which the sterile composition exhibits greater stability over time and/or during heat treatment resulting in sterilization in comparison to the same composition having lidocaine as the anesthetic agent instead of mepivacaine.

公开(公告)号：US20190183783A1

公开(公告)日：2019-06-20

申请号：US16326798

申请日：2017-08-16

Applicant: Georg Fritzmeier GmbH & Co. KG

Inventor： Ursula Fritzmeier ,  Birgit Lewandowski

IPC: A61K8/99 ,  A61K8/73 ,  A61K8/06 ,  A61K8/04 ,  A61Q19/00 ,  A61K9/00 ,  A61K35/747 ,  A61K35/744 ,  A61K31/722 ,  A61K31/728 ,  A61K9/06 ,  A61K9/107

CPC classification number: A61K8/99 ,  A61K8/042 ,  A61K8/062 ,  A61K8/735 ,  A61K8/736 ,  A61K9/0014 ,  A61K9/0034 ,  A61K9/06 ,  A61K9/107 ,  A61K31/722 ,  A61K31/728 ,  A61K35/744 ,  A61K35/747 ,  A61K47/36 ,  A61K2800/75 ,  A61Q19/005 ,  A61Q19/007

Abstract: Disclosed is a skin care composition with a carrier substance and a proportion of lactic acid bacteria or their metabolic products.

公开(公告)号：US20180185301A1

公开(公告)日：2018-07-05

申请号：US15736494

申请日：2016-06-19

Applicant: Symrise AG

Inventor： Gerhard Schmaus ,  Sabine Lange

IPC: A61K31/08 ,  A61K31/25 ,  A61K8/39 ,  A61Q5/00 ,  A61Q5/12 ,  A61Q15/00 ,  A61Q17/04 ,  A61Q19/00 ,  A61Q19/02

CPC classification number: A61K31/08 ,  A61K8/33 ,  A61K8/39 ,  A61K31/25 ,  A61K31/765 ,  A61K45/06 ,  A61K2800/75 ,  A61Q5/006 ,  A61Q5/12 ,  A61Q15/00 ,  A61Q17/04 ,  A61Q19/00 ,  A61Q19/004 ,  A61Q19/005 ,  A61Q19/02 ,  A61K2300/00

Abstract: Suggested are compositions comprising or consisting of specific polyalkylene glycol derivative as pharmaceutical actives for preventing, treating and/or curing itchy conditions of human skin and scalp, and/or providing a PAR-2 antagonistic effect to human skin and scalp.

公开(公告)号：US20180133126A1

公开(公告)日：2018-05-17

申请号：US15846870

申请日：2017-12-19

Applicant: Carrie D. Alspaugh, M.D., P.A.

Inventor： James Andrew Alspaugh, II ,  Carrie Deener Alspaugh

IPC: A61K8/20 ,  A61K8/25 ,  A61K8/27 ,  A61K8/29 ,  A61K8/36 ,  A61K8/46 ,  A61K8/49 ,  A61K8/67 ,  A61K8/92 ,  A61Q17/00 ,  A61Q17/02 ,  A61Q17/04 ,  A61Q19/00 ,  A61Q19/10

CPC classification number: A61K8/20 ,  A01N59/00 ,  A61K8/25 ,  A61K8/27 ,  A61K8/29 ,  A61K8/361 ,  A61K8/466 ,  A61K8/496 ,  A61K8/4966 ,  A61K8/67 ,  A61K8/922 ,  A61K2800/30 ,  A61K2800/522 ,  A61K2800/56 ,  A61K2800/75 ,  A61Q17/005 ,  A61Q17/02 ,  A61Q17/04 ,  A61Q19/005 ,  A61Q19/10 ,  C01B11/04 ,  C01B13/10 ,  A01N25/04

Abstract: The present invention provides a sanitizing composition including a sanitizing effective amount of an agent selected from the group consisting of hypochlorous acid, sodium hypochlorite, calcium hypochlorite and combinations thereof in a carrier wherein the composition is substantially free of a drying alcohol. The present invention further provides methods of using the sanitizing compositions and articles of manufacture including the sanitizing compositions.

公开(公告)号：US09949919B2

公开(公告)日：2018-04-24

申请号：US14747781

申请日：2015-06-23

Applicant: SHAMROC, INC.

Inventor： Ronald M. Gurge ,  Mark W. Trumbore ,  Nupoor Devrajbhai Hirani

IPC: A61K8/97 ,  A61K8/64 ,  A61Q19/02 ,  A61K8/36 ,  A61K8/42 ,  A61Q19/00 ,  A61K8/49 ,  A61K8/60 ,  A61K8/34 ,  A61K8/67 ,  A61K8/9706

CPC classification number: A61K8/97 ,  A61K8/342 ,  A61K8/345 ,  A61K8/347 ,  A61K8/36 ,  A61K8/42 ,  A61K8/494 ,  A61K8/4946 ,  A61K8/498 ,  A61K8/602 ,  A61K8/64 ,  A61K8/675 ,  A61K8/9706 ,  A61K2800/75 ,  A61Q19/00 ,  A61Q19/02

Abstract: Described herein are methods and compositions for increasing the efficacy and decreasing the irritancy of topical formulations of hydroquinone.

公开(公告)号：US09889083B2

公开(公告)日：2018-02-13

申请号：US14698992

申请日：2015-04-29

Applicant: Henkel AG & Co. KGaA

Inventor： Fumika Ikeno ,  Masaki Kawai ,  Shoji Machida ,  Kota Uchida ,  Akira Matsutani ,  Maki Miyamoto

IPC: A61Q5/00 ,  A61Q5/10 ,  A61K8/86 ,  A61K8/41 ,  A61K8/34 ,  A61K8/22 ,  A61Q5/08

CPC classification number: A61K8/86 ,  A61K8/19 ,  A61K8/22 ,  A61K8/34 ,  A61K8/342 ,  A61K8/415 ,  A61K2800/4324 ,  A61K2800/75 ,  A61K2800/88 ,  A61Q5/08 ,  A61Q5/10

Abstract: The present invention provides a two-part hair cosmetic material having a reduced irritating smell due to ammonia. Specifically, the present invention relates to a two-part hair cosmetic material comprising a first agent containing an alkali agent and a second agent containing an oxidizing agent, wherein the first agent contains the following ingredients: (A) a polyoxyethylene alkyl ether having a polyoxyethylene chain length of 50 or more, (B) a higher alcohol, and (C) a polyoxyethylene alkyl ether having a polyoxyethylene chain length shorter than the polyoxyethylene chain length of the polyoxyethylene alkyl ether (A), and the content of a higher alcohol having 20 or more carbon atoms in the higher alcohol (B) is 1.0% by weight or less based on the weight of the first agent.

公开(公告)号：US20170369414A1

公开(公告)日：2017-12-28

申请号：US15541790

申请日：2015-01-12

Applicant: Institut des Substances Végétales

Inventor： Daniel Jean ,  Maryse Pouligon

IPC: C07C59/84 ,  A61K9/00 ,  A61K8/36 ,  A61K31/192 ,  A61Q19/00 ,  A61K36/68

CPC classification number: C07C59/84 ,  A61K8/36 ,  A61K8/365 ,  A61K8/602 ,  A61K8/97 ,  A61K9/0053 ,  A61K31/122 ,  A61K31/192 ,  A61K31/7034 ,  A61K36/68 ,  A61K2800/10 ,  A61K2800/522 ,  A61K2800/75 ,  A61Q7/00 ,  A61Q15/00 ,  A61Q19/00 ,  A61Q19/005 ,  A61Q19/007 ,  A61Q19/06 ,  A61Q19/08 ,  A61Q19/10

Abstract: The invention relates to O-quinone compounds of general formula (I) as agents neutralising nitric oxide, and to the therapeutic or cosmetic use thereof.

公开(公告)号：US09833469B2

公开(公告)日：2017-12-05

申请号：US15387138

申请日：2016-12-21

Applicant: Ronald E. Utecht ,  Therese M. Downey ,  Miri Seiberg ,  Stanley S. Shapiro

Inventor： Ronald E. Utecht ,  Therese M. Downey ,  Miri Seiberg ,  Stanley S. Shapiro

IPC: A61K31/737 ,  A61K8/73 ,  A61F13/84 ,  A61Q19/08 ,  A61K31/05 ,  A61K9/00 ,  A61K8/34

CPC classification number: A61K31/737 ,  A61F13/8405 ,  A61K8/347 ,  A61K8/671 ,  A61K8/736 ,  A61K9/0014 ,  A61K31/05 ,  A61K31/07 ,  A61K31/185 ,  A61K31/203 ,  A61K31/722 ,  A61K45/06 ,  A61K2800/75 ,  A61K2800/782 ,  A61Q19/08 ,  A61K2300/00

Abstract: Compositions are described that contain treated chitosan, modified chitosan and/or modified and treated chitosan for use in formulations for skin, hair and nails, and in compositions and methods of reducing topical agent-induced skin irritation and inflammation.

公开(公告)号：US09827176B2

公开(公告)日：2017-11-28

申请号：US14813226

申请日：2015-07-30

Applicant: Shirley Johnson

Inventor： Shirley Johnson

IPC: A61K8/26 ,  A61Q15/00 ,  A61K31/085 ,  A61K31/341 ,  A61K31/045 ,  A61K31/704 ,  A61K31/01 ,  A61K31/00

CPC classification number: A61K8/26 ,  A61K8/34 ,  A61K8/4973 ,  A61K8/602 ,  A61K31/00 ,  A61K31/01 ,  A61K31/045 ,  A61K31/085 ,  A61K31/341 ,  A61K31/704 ,  A61K2800/75 ,  A61K2800/77 ,  A61Q15/00 ,  A61Q17/005

Abstract: A prophylactic cream, ointment or deodorant for the prevention of the formation of yeast infections.