-
公开(公告)号：US10413637B2
公开(公告)日：2019-09-17
申请号：US16282598
申请日：2019-02-22
Applicant: Teoxane
Inventor： Francois Bourdon , Stephane Meunier
IPC: A61L27/54 , A61Q19/08 , A61K31/728 , A61K31/16 , A61K8/49 , A61K31/167 , A61L27/20 , A61L27/12 , A61K9/00 , A61K8/24 , A61K8/73 , A61K31/445 , A61K31/451 , A61K47/02
Abstract: A sterile composition for intraepidermal, intradermal, and/or subcutaneous administration including an effective amount of hyaluronic acid or a salt thereof, the effective amount of hyaluronic acid or salt thereof ranging from 1 to 3 wt % of the overall weight of the sterile composition, mepivacaine or a salt thereof as a first anesthetic agent at a concentration ranging from 0.05 to 3 wt % of an overall weight of the sterile composition, and a balanced salt solution in which the sterile composition exhibits greater stability over time and/or during heat treatment resulting in sterilization in comparison to the same composition having lidocaine as the anesthetic agent instead of mepivacaine.
-
公开(公告)号：US10322212B2
公开(公告)日：2019-06-18
申请号：US15895220
申请日：2018-02-13
Applicant: Teoxane
Inventor： Francois Bourdon , Stephane Meunier
IPC: A61L27/20 , A61K8/49 , A61K8/73 , A61K9/00 , A61K31/16 , A61K47/02 , A61L27/54 , A61Q19/08 , A61K31/167 , A61K31/445 , A61K31/451 , A61K31/728 , A61L27/12 , A61K8/24
Abstract: Compositions and methods for the surface appearance of the skin a subject are provided. An injectable composition comprising at least hyaluronic acid or a salt thereof; and an effective amount of at least mepivacaine or a salt thereof are provided. The hyaluronic acid optionally has an average molecular weight ranging from 50,000 to 10,000,000 Daltons, and may be crosslinked hyaluronic acids, non-crosslinked hyaluronic acids, or a combination, in some embodiments. The compositions and methods of the present invention are useful for treating and preventing the cutaneous signs of chronological aging and/or induced by external factors such as stress, air pollution, tobacco or prolonged exposure to ultraviolet (UV) exposure, impaired surface appearance of the skin, impaired viscoelastic or biomechanical properties of the skin, and/or the long-lasting filling of volume defects of the skin.
-
公开(公告)号：US20220362439A1
公开(公告)日：2022-11-17
申请号：US17862711
申请日：2022-07-12
Applicant: Teoxane
Inventor： Francois Bourdon , Stephane Meunier
IPC: A61L27/54 , A61K8/49 , A61K31/167 , A61K31/451 , A61K31/728 , A61K8/73 , A61Q19/08 , A61K31/16 , A61K31/445 , A61K8/24 , A61K9/00 , A61K47/02 , A61L27/12 , A61L27/20
Abstract: Compositions and methods for the surface appearance of the skin a subject are provided. An injectable composition comprising at least hyaluronic acid or a salt thereof; and an effective amount of at least mepivacaine or a salt thereof are provided. The hyaluronic acid optionally has an average molecular weight ranging from 50,000 to 10,000,000 Daltons, and may be crosslinked hyaluronic acids, non-crosslinked hyaluronic acids, or a combination, in some embodiments. The compositions and methods of the present invention are useful for treating and preventing the cutaneous signs of chronological aging and/or induced by external factors such as stress, air pollution, tobacco or prolonged exposure to ultraviolet (UV) exposure, impaired surface appearance of the skin, impaired viscoelastic or biomechanical properties of the skin, and/or the long-lasting filling of volume defects of the skin.
-
公开(公告)号：US09789226B2
公开(公告)日：2017-10-17
申请号：US15044236
申请日：2016-02-16
Applicant: Teoxane
Inventor： Francois Bourdon , Stephane Meunier
IPC: A61L27/54 , A61L27/20 , A61K9/00 , A61K47/02 , A61Q19/08 , A61K8/73 , A61K31/16 , A61K31/728 , A61K8/49 , A61K31/445 , A61K31/451 , A61K31/167 , A61L27/12 , A61K8/24
CPC classification number: A61L27/54 , A61K8/24 , A61K8/4926 , A61K8/735 , A61K9/0019 , A61K9/0024 , A61K31/16 , A61K31/167 , A61K31/445 , A61K31/451 , A61K31/728 , A61K47/02 , A61K2800/524 , A61K2800/75 , A61K2800/91 , A61L27/12 , A61L27/20 , A61L2300/204 , A61L2300/402 , A61L2400/06 , A61Q19/08 , A61K2300/00
Abstract: Compositions and methods for the surface appearance of the skin a subject are provided. An injectable composition comprising at least hyaluronic acid or a salt thereof; and an effective amount of at least mepivacaine or a salt thereof are provided. The hyaluronic acid optionally has an average molecular weight ranging from 50,000 to 10,000,000 Daltons, and may be crosslinked hyaluronic acids, non-crosslinked hyaluronic acids, or a combination, in some embodiments. The compositions and methods of the present invention are useful for treating and preventing the cutaneous signs of chronological aging and/or induced by external factors such as stress, air pollution, tobacco or prolonged exposure to ultraviolet (UV) exposure, impaired surface appearance of the skin, impaired viscoelastic or biomechanical properties of the skin, and/or the long-lasting filling of volume defects of the skin.
-
公开(公告)号：US10786601B2
公开(公告)日：2020-09-29
申请号：US16037402
申请日：2018-07-17
Applicant: Teoxane
Inventor： Francois Bourdon , Stephane Meunier
IPC: A61L27/54 , A61K31/728 , A61K8/73 , A61K31/16 , A61K9/00 , A61L27/20 , A61K8/49 , A61K31/167 , A61K31/451 , A61Q19/08 , A61K31/445 , A61K8/24 , A61K47/02 , A61L27/12
Abstract: Compositions and methods for the surface appearance of the skin a subject are provided. An injectable composition comprising at least hyaluronic acid or a salt thereof; and an effective amount of at least mepivacaine or a salt thereof are provided. The hyaluronic acid optionally has an average molecular weight ranging from 50,000 to 10,000,000 Daltons, and may be crosslinked hyaluronic acids, non-crosslinked hyaluronic acids, or a combination, in some embodiments. The compositions and methods of the present invention are useful for treating and preventing the cutaneous signs of chronological aging and/or induced by external factors such as stress, air pollution, tobacco or prolonged exposure to ultraviolet (UV) exposure, impaired surface appearance of the skin, impaired viscoelastic or biomechanical properties of the skin, and/or the long-lasting filling of volume defects of the skin.
-
Patent Agency Ranking
公开(公告)号：US10132734B2
公开(公告)日：2018-11-20
申请号：US15560547
申请日：2016-03-22
Applicant: TEOXANE
Inventor： Francois Bourdon , Stephane Meunier
Abstract: Process for evaluating the mechanical performance of a filler gel, comprising the step consisting in subjecting a sample of this gel to oscillating mechanical stresses making it possible to determine the elastic modulus G′ and to deliver a score representative of the integration of G′ over the stress and/or the deformation strain within a stress and/or strain interval that includes values of the modulus G′ encountered beyond the linear viscoelasticity plateau.
-
公开(公告)号：US20170354761A1
公开(公告)日：2017-12-14
申请号：US15536039
申请日：2015-12-15
Applicant: Teoxane
Inventor： Francois Bourdon , Stephane Meunier
CPC classification number: A61L27/52 , A61K8/042 , A61K8/24 , A61K8/735 , A61K9/06 , A61K31/728 , A61K2800/91 , A61L27/20 , A61L2400/06 , A61L2430/16 , A61L2430/24 , A61Q11/00 , A61Q19/08 , C08B37/0072 , C08L5/08
Abstract: The present invention relates to a process for preparing a crosslinked gel of at least one polysaccharide or a salt thereof, comprising at least the steps consisting in: a) providing a solution formed from an aqueous medium comprising at least said polysaccharide(s) or a salt thereof in a non-crosslinked form, at least one difunctional or multifunctional epoxide crosslinking agent chosen from butanediol diglycidyl ether, diepoxyoctane, 1,2-bis(2,3-epoxypropyl)-2,3-ethylene, and mixtures thereof, and at least one phosphate salt; b) crosslinking the solution from step a) and, where appropriate; c) recovering said crosslinked gel formed.
-
公开(公告)号：US20180318469A1
公开(公告)日：2018-11-08
申请号：US16037402
申请日：2018-07-17
Applicant: Teoxane
Inventor： Francois Bourdon , Stephane Meunier
IPC: A61L27/54 , A61K8/73 , A61L27/20 , A61L27/12 , A61K9/00 , A61K8/24 , A61K47/02 , A61K31/445 , A61K31/451 , A61K31/167 , A61K8/49 , A61K31/16 , A61Q19/08 , A61K31/728
Abstract: Compositions and methods for the surface appearance of the skin a subject are provided. An injectable composition comprising at least hyaluronic acid or a salt thereof; and an effective amount of at least mepivacaine or a salt thereof are provided. The hyaluronic acid optionally has an average molecular weight ranging from 50,000 to 10,000,000 Daltons, and may be crosslinked hyaluronic acids, non-crosslinked hyaluronic acids, or a combination, in some embodiments. The compositions and methods of the present invention are useful for treating and preventing the cutaneous signs of chronological aging and/or induced by external factors such as stress, air pollution, tobacco or prolonged exposure to ultraviolet (UV) exposure, impaired surface appearance of the skin, impaired viscoelastic or biomechanical properties of the skin, and/or the long-lasting filling of volume defects of the skin.
-
公开(公告)号：US20180169304A1
公开(公告)日：2018-06-21
申请号：US15895220
申请日：2018-02-13
Applicant: Teoxane
Inventor： FRANCOIS BOURDON , Stephane Meunier
IPC: A61L27/54 , A61K9/00 , A61K8/24 , A61K31/451 , A61L27/20 , A61L27/12 , A61K31/445 , A61K47/02 , A61Q19/08 , A61K8/49 , A61K31/16 , A61K8/73 , A61K31/167 , A61K31/728
CPC classification number: A61L27/54 , A61K8/24 , A61K8/4926 , A61K8/735 , A61K9/0019 , A61K9/0024 , A61K31/16 , A61K31/167 , A61K31/445 , A61K31/451 , A61K31/728 , A61K47/02 , A61K2800/524 , A61K2800/75 , A61K2800/91 , A61L27/12 , A61L27/20 , A61L2300/204 , A61L2300/402 , A61L2400/06 , A61Q19/08 , A61K2300/00
Abstract: Compositions and methods for the surface appearance of the skin a subject are provided. An injectable composition comprising at least hyaluronic acid or a salt thereof; and an effective amount of at least mepivacaine or a salt thereof are provided. The hyaluronic acid optionally has an average molecular weight ranging from 50,000 to 10,000,000 Daltons, and may be crosslinked hyaluronic acids, non-crosslinked hyaluronic acids, or a combination, in some embodiments. The compositions and methods of the present invention are useful for treating and preventing the cutaneous signs of chronological aging and/or induced by external factors such as stress, air pollution, tobacco or prolonged exposure to ultraviolet (UV) exposure, impaired surface appearance of the skin, impaired viscoelastic or biomechanical properties of the skin, and/or the long-lasting filling of volume defects of the skin.
-
公开(公告)号：US09498562B1
公开(公告)日：2016-11-22
申请号：US15214983
申请日：2016-07-20
Applicant: Teoxane
Inventor： Francois Bourdon , Stephane Meunier
CPC classification number: A61L27/54 , A61K8/24 , A61K8/4926 , A61K8/735 , A61K9/0019 , A61K9/0024 , A61K31/16 , A61K31/167 , A61K31/445 , A61K31/451 , A61K31/728 , A61K47/02 , A61K2800/524 , A61K2800/75 , A61K2800/91 , A61L27/12 , A61L27/20 , A61L2300/204 , A61L2300/402 , A61L2400/06 , A61Q19/08 , A61K2300/00
Abstract: Compositions and methods for the surface appearance of the skin a subject are provided. An injectable composition comprising at least hyaluronic acid or a salt thereof; and an effective amount of at least mepivacaine or a salt thereof are provided. The hyaluronic acid optionally has an average molecular weight ranging from 50,000 to 10,000,000 Daltons, and may be crosslinked hyaluronic acids, non-crosslinked hyaluronic acids, or a combination, in some embodiments. The compositions and methods of the present invention are useful for treating and preventing the cutaneous signs of chronological aging and/or induced by external factors such as stress, air pollution, tobacco or prolonged exposure to ultraviolet (UV) exposure, impaired surface appearance of the skin, impaired viscoelastic or biomechanical properties of the skin, and/or the long-lasting filling of volume defects of the skin.
Abstract translation: 提供了一种用于皮肤受试者表面外观的组合物和方法。 一种至少含有透明质酸或其盐的可注射组合物; 并提供有效量的至少甲哌卡因或其盐。 透明质酸任选地具有50,000至10,000,000道尔顿的平均分子量，并且在一些实施方案中可以是交联的透明质酸，非交联透明质酸或组合。 本发明的组合物和方法可用于治疗和预防皮肤老化迹象和/或外部因素如应激，空气污染，烟草或长时间暴露于紫外线（UV）暴露，受损的表面外观， 皮肤，皮肤受损的粘弹性或生物力学性质，和/或皮肤体积缺陷的持久的填充。
-
-
-
-
-
-
-
-
-
Search Results
17
records
(took 0.036 seconds)
