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公开(公告)号：US20080223465A1
公开(公告)日：2008-09-18
申请号：US12048191
申请日：2008-03-13
Applicant: David Deng
Inventor： David Deng
CPC classification number: F23C1/00 , F23D14/00 , F23D14/48 , F23D14/62 , F23D2207/00 , F23D2208/00 , F23D2900/21004 , F23K2900/05002 , F23N1/00 , F23N1/007 , F23N2035/18 , F23N2041/02 , Y10T137/0324 , Y10T137/2567 , Y10T137/8376 , Y10T137/86493 , Y10T137/86541 , Y10T137/86815 , Y10T137/87096 , Y10T137/87249 , Y10T137/87611
Abstract: In certain embodiments, an apparatus includes a control valve for regulating fuel flow. The apparatus can include a burner and a valve assembly. In some embodiments, the valve assembly includes a housing, which can define a first fuel input for receiving a first fuel from a first fuel source and a second fuel input for receiving a second fuel from a second fuel source. The housing can define a first fuel output for directing fuel toward the control valve, and can define a third fuel input for receiving a portion of either the first fuel or the second fuel from the control valve. The housing can define a first egress flow path and a second egress flow path, each for directing fuel to the burner. In certain embodiments, the apparatus includes a valve body configured to selectively permit fluid communication between the first and second inputs and the output and between the third input and the egress flow paths.
Abstract translation: 在某些实施例中，装置包括用于调节燃料流量的控制阀。 该装置可以包括燃烧器和阀组件。 在一些实施例中，阀组件包括壳体，壳体可以限定用于从第一燃料源接收第一燃料的第一燃料输入和用于从第二燃料源接收第二燃料的第二燃料输入。 壳体可以限定用于将燃料引向控制阀的第一燃料输出，并且可以限定用于从控制阀接收第一燃料或第二燃料的一部分的第三燃料输入。 壳体可以限定第一出口流动路径和第二出口流动路径，每个流动路径用于将燃料引导到燃烧器。 在某些实施例中，该装置包括阀体，其构造成选择性地允许第一和第二输入与输出之间以及第三输入与出口流动路径之间的流体连通。
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22.发明申请System and Methods for Determining an Analyte Concentration Incorporating a Hematocrit Correction 审中-公开用于确定血细胞比容校正的分析物浓度的系统和方法公开(公告)号：US20080083618A1
公开(公告)日：2008-04-10
申请号：US11845860
申请日：2007-08-28
Applicant: Gary Neel , Douglas Bell , Dennis Slomski , David Deng
Inventor： Gary Neel , Douglas Bell , Dennis Slomski , David Deng
CPC classification number: A61B5/14546 , A61B5/14535 , A61B5/1486 , A61B2560/0209 , A61B2562/0295 , A61B2562/085 , C12Q1/006 , G01N27/3272 , G01N27/3274 , G01N33/66 , Y10T29/49117
Abstract: Methods and devices for determining the concentration of a constituent in a physiological sample are provided. The blood sample is introduced into a test strip with portions of the blood sample being directed to both a first capillary and a second capillary. The first capillary configured to electrochemically determine a concentration of a first analyte in a blood sample by measuring a signal across a set of electrodes. The second capillary is configured to determine a hematocrit value of the blood sample by measuring a signal across a second set of electrodes.
Abstract translation: 提供了用于确定生理样品中成分浓度的方法和装置。 将血液样品引入测试条中，其中部分血液样品被引导到第一毛细管和第二毛细管。 第一毛细管构造成通过测量跨越一组电极的信号来电化学地确定血液样品中的第一分析物的浓度。 第二毛细管被配置为通过测量跨越第二组电极的信号来确定血液样品的血细胞比容值。
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23.再颁专利公开(公告)号：USRE40198E1
公开(公告)日：2008-04-01
申请号：US10671436
申请日：2003-09-25
Applicant: Harvey B. Buck, Jr. , Zhi David Deng , Eric R. Diebold
Inventor： Harvey B. Buck, Jr. , Zhi David Deng , Eric R. Diebold
IPC: G01N27/327
CPC classification number: C07F15/0026 , C07K5/101 , C07K7/02 , C07K7/06 , C07K9/001 , C07K14/805 , G01N27/3277 , G01N33/532 , G01N33/536 , G01N33/58 , G01N33/723 , G01N2333/805 , G01N2458/30 , Y10S436/805 , Y10S436/806 , Y10T436/105831
Abstract: A method and device for detection and quantification of biologically significant analytes in a liquid sample is described. The method includes contacting a volume of a liquid sample with predetermined amounts of at least a first and second redox reversible species having redox potentials differing by at least 50 millivolts. At least one of the redox reversible species comprises a liquid sample diffusible conjugate of a ligand analog of an analyte in the liquid sample and a redox reversible label. A predetermined amount of at least one specific binding partner for each analyte to be measured is combined with the sample and current flow is measured at first and second anodic and cathodic potentials and correlated with current flows for known concentrations of the respective diffusible redox reversible species. Diagnostic devices and kits, including such devices and the specified specific binding partner(s) and redox reversible species are also described.
Abstract translation: 描述了用于在液体样品中检测和定量生物学显着性分析物的方法和装置。 该方法包括使体积的液体样品与预定量的至少50毫伏的氧化还原电位的至少第一和第二氧化还原可逆物质接触。 至少一种氧化还原可逆物质包括液体样品中分析物的配体类似物和氧化还原可逆标记的液体样品可扩散共轭物。 将待测量的每种待测量分析物的至少一个特定结合配偶体的预定量与样品组合，并且在第一和第二阳极和阴极电位处测量电流，并且与已知浓度的各个可扩散的氧化还原可逆物质的电流相关。 还描述了诊断装置和试剂盒，包括这些装置和指定的特异性结合配偶体和氧化还原可逆物质。
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公开(公告)号：US20070286772A1
公开(公告)日：2007-12-13
申请号：US11783568
申请日：2007-04-10
Applicant: Natasha Popovich , Dennis Slomski , David Deng
Inventor： Natasha Popovich , Dennis Slomski , David Deng
CPC classification number: G01N27/3272
Abstract: A biosensor having a first conductive component is described, wherein the first conductive component includes at least one boundary formed by a first processing technique and at least one boundary formed by a second processing technique not the same as the first processing technique. The biosensor can also have a second conductive component including at least one boundary formed by the first processing technique and at least one boundary formed by a third processing technique not the same as the first processing technique. Further, the biosensor has a third conductive component including at least one boundary formed by the second processing technique and at least one boundary formed by the third processing technique not the same as the second processing technique.
Abstract translation: 描述具有第一导电部件的生物传感器，其中第一导电部件包括由第一处理技术形成的至少一个边界和由与第一处理技术不相同的第二处理技术形成的至少一个边界。 生物传感器还可以具有包括由第一处理技术形成的至少一个边界和由与第一处理技术不相同的第三处理技术形成的至少一个边界的第二导电部件。 此外，生物传感器具有包括由第二处理技术形成的至少一个边界和由与第二处理技术不相同的第三处理技术形成的至少一个边界的第三导电成分。
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25.发明申请公开(公告)号：US20070253901A1
公开(公告)日：2007-11-01
申请号：US11412437
申请日：2006-04-27
Applicant: David Deng , Anya Tsalenko , Amir Ben-Dor , Zohar Yakhini , Thomas Quertermous , Euan Ashley , Eugene Yang , Raymond Tabibiazar , Philip Tsao
Inventor： David Deng , Anya Tsalenko , Amir Ben-Dor , Zohar Yakhini , Thomas Quertermous , Euan Ashley , Eugene Yang , Raymond Tabibiazar , Philip Tsao
CPC classification number: G01N33/6893 , G01N2800/323
Abstract: The invention provides genes (DEA genes) that are differentially expressed in atherosclerotic lesions and polypeptides encoded by these genes. The invention provides compositions comprising a targeting agent conjugated to a functional moiety, wherein the targeting agent selectively binds to a polypeptide encoded by one a DEA gene. The functional moiety can be an imaging agent, therapeutic agent, etc. The invention further provides methods for providing diagnostic or prognostic information related to atherosclerosis involving detecting expression or activity of an expression product of one or more of the DEA genes. The invention further provides therapeutic methods comprising administering to a subject a composition comprising a targeting agent conjugated to a functional moiety that binds selectively binds to a polypeptide encoded by a DEA gene.
Abstract translation: 本发明提供在动脉粥样硬化病变和由这些基因编码的多肽中差异表达的基因（DEA基因）。 本发明提供了包含与功能部分缀合的靶向剂的组合物，其中所述靶向剂选择性地结合由DEA基因之一编码的多肽。 功能部分可以是显像剂，治疗剂等。本发明还提供了提供涉及检测一种或多种DEA基因的表达产物的表达或活性的动脉粥样硬化相关的诊断或预后信息的方法。 本发明进一步提供治疗方法，包括向受试者施用包含与功能性部分缀合的靶向试剂的组合物，其结合选择性结合由DEA基因编码的多肽。
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Patent Agency Ranking
公开(公告)号：US07045310B2
公开(公告)日：2006-05-16
申请号：US09999110
申请日：2001-11-01
Applicant: Harvey B. Buck, Jr. , Zhi David Deng , Eric R. Diebold
Inventor： Harvey B. Buck, Jr. , Zhi David Deng , Eric R. Diebold
CPC classification number: C07F15/0026 , C07K5/101 , C07K7/02 , C07K7/06 , C07K9/001 , C07K14/805 , G01N27/3277 , G01N33/532 , G01N33/536 , G01N33/58 , G01N33/723 , G01N2333/805 , G01N2458/30 , Y10S436/805 , Y10S436/806 , Y10T436/105831
Abstract: Novel bipyridyl-osmium complex conjugates and their use in electrochemical assays are described. The redox reversible-osmium complexes can be prepared to exhibit unique reversible redox potentials and can thus be used in combination with other electroactive redox reversible species having redox potentials differing by at least 50 millivolts in electrochemical assays designed for use of multiple electroactive species in the same cell and in the same sample without interference between the two or more redox coupled conjugate systems.
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公开(公告)号：US20060063162A1
公开(公告)日：2006-03-23
申请号：US10948716
申请日：2004-09-23
Applicant: David Deng
Inventor： David Deng
CPC classification number: G01N33/689 , C12Q1/6837 , C12Q1/6883 , C12Q2600/158 , G01N33/6893 , G01N2333/471 , G01N2800/368 , G01N2800/52
Abstract: The present disclosure provides methods and compositions for the diagnosis and treatment of inflammation, in particular, vascular pathologies. One aspect provides an array capable of detecting the expression pregnancy specific glycoproteins in a non-pregnant patient. The array optionally detects at least a second biomarker for vascular pathology. Compositions and methods including modulators of pregnancy specific glycoproteins are also provided.
Abstract translation: 本公开提供了用于诊断和治疗炎症，特别是血管病变的方法和组合物。 一方面提供了能够检测非怀孕患者中怀孕特异性糖蛋白表达的阵列。 该阵列任选地检测至少一种用于血管病理学的第二生物标志物。 还提供了包括怀孕特异性糖蛋白调节剂的组合物和方法。
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公开(公告)号：US06923985B2
公开(公告)日：2005-08-02
申请号：US09923118
申请日：2001-08-06
Applicant: Dale R. Peterson , Z. David Deng , Todd P. Glancy
Inventor： Dale R. Peterson , Z. David Deng , Todd P. Glancy
IPC: A61L27/00 , A61K9/20 , A61L24/00 , A61L24/04 , A61L27/04 , A61L27/18 , A61L27/46 , C09J9/00 , A61K9/10 , A61K47/34 , A61K31/765 , C08G63/08
CPC classification number: A61L27/18 , A61K9/204 , A61L24/0073 , A61L24/0084 , A61L24/046 , A61L27/04 , A61L27/46 , C08L67/04 , Y10S528/931
Abstract: Improved matrices and adhesives for tissue repair comprising a biocompatible, bioerodable polymer, said polymer comprising a thermoplastic lactide-containing terpolymer of monomer units derived from lactic acid, glycolic acid, and either caprolactone or valerolactone, which has a water solubility of about 0.01 to about 500 mg/mL at about 25° C. and adhesive strength of about 600 to about 150,000 Pa. The matrix or adhesive can further comprise a filler or a bioactive agent, or both.
Abstract translation: 用于组织修复的改进的基质和粘合剂，其包含生物相容的可生物侵蚀的聚合物，所述聚合物包含衍生自乳酸，乙醇酸和己内酯或戊内酯的单体单元的热塑性丙交酯三元共聚物，其水溶解度为约0.01至约 在约25℃下为500mg / mL，粘合强度为约600至约150,000Pa。基质或粘合剂可进一步包含填料或生物活性剂，或两者。
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公开(公告)号：US06326025B1
公开(公告)日：2001-12-04
申请号：US09530172
申请日：2000-04-24
Applicant: Gerry Sigler , Z. David Deng , Dale R. Peterson , Todd P. Glancy , Samuel I. Stupp
Inventor： Gerry Sigler , Z. David Deng , Dale R. Peterson , Todd P. Glancy , Samuel I. Stupp
IPC: A61F1302
CPC classification number: A61L24/04 , C08L101/02 , Y10S602/904
Abstract: The present invention is directed to a biocompatible tissue reactive composition comprising a functionalized polymer having tissue reactive substituents that are capable of forming covalent bonds with tissue associated functional groups.
Abstract translation: 本发明涉及生物相容性组织反应性组合物，其包含具有能与组织相关官能团形成共价键的组织反应性取代基的官能化聚合物。
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公开(公告)号：US06168225A
公开(公告)日：2001-01-02
申请号：US09255378
申请日：1999-02-22
Applicant: David Deng , Dai Lei
Inventor： David Deng , Dai Lei
IPC: B60J720
Abstract: A apparatus for covering automobile windshields includes a housing adapted to be secured to an automobile roof and a canopy movable between a retracted position substantially aligned with the housing and an extended position substantially aligned with the windshield.
Abstract translation: 用于覆盖汽车挡风玻璃的装置包括适于固定到汽车车顶的壳体和在基本上与壳体对准的缩回位置与基本上与挡风玻璃对准的延伸位置之间可移动的罩盖。
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