公开(公告)号：US10366856B2

公开(公告)日：2019-07-30

申请号：US15442408

申请日：2017-02-24

Applicant: California Institute of Technology

Inventor： Axel Scherer ,  William M. Jones ,  Danil M. Lukin ,  Sameer Walavalkar ,  Chieh-feng Chang

IPC: H01J19/24 ,  H01J9/02 ,  H01J21/02

Abstract: Nanoscale field-emission devices are presented, wherein the devices include at least a pair of electrodes separated by a gap through which field emission of electrons from one electrode to the other occurs. The gap is dimensioned such that only a low voltage is required to induce field emission. As a result, the emitted electrons energy that is below the ionization potential of the gas or gasses that reside within the gap. In some embodiments, the gap is small enough that the distance between the electrodes is shorter than the mean-free path of electrons in air at atmospheric pressure. As a result, the field-emission devices do not require a vacuum environment for operation.

公开(公告)号：US09960238B2

公开(公告)日：2018-05-01

申请号：US14720429

申请日：2015-05-22

Applicant: CALIFORNIA INSTITUTE OF TECHNOLOGY ,  SANOFI

Inventor： Aditya Rajagopal ,  Chieh-feng Chang ,  Oliver Plettenburg ,  Stefan Petry ,  Axel Scherer ,  Charles L. Tschirhart

IPC: H01L29/00 ,  H01L29/41 ,  H01L29/73 ,  H01L29/78 ,  B82Y15/00 ,  H01L29/732 ,  H01L29/06 ,  G01N27/414 ,  H01L29/45 ,  H01L29/49 ,  H01L29/735

CPC classification number: H01L29/413 ,  B82Y15/00 ,  G01N27/4145 ,  G01N27/4146 ,  H01L29/0676 ,  H01L29/45 ,  H01L29/49 ,  H01L29/73 ,  H01L29/732 ,  H01L29/735 ,  H01L29/78

Abstract: Systems and methods for molecular sensing are described. Molecular sensors are described which are based on field-effect or bipolar junction transistors. These transistors have a nanopillar with a functionalized layer contacted to either the base or the gate electrode. The functional layer can bind molecules, which causes an electrical signal in the sensor.

公开(公告)号：US09993185B2

公开(公告)日：2018-06-12

申请号：US14621265

申请日：2015-02-12

Applicant: CALIFORNIA INSTITUTE OF TECHNOLOGY

Inventor： Sameer Walavalkar ,  Chieh-feng Chang ,  Axel Scherer

IPC: G01N21/65 ,  A61B5/1459 ,  A61B5/00 ,  B82Y40/00 ,  A61B5/1473 ,  A61B5/07 ,  B82Y30/00

CPC classification number: A61B5/1459 ,  A61B5/0075 ,  A61B5/076 ,  A61B5/14735 ,  A61B5/6848 ,  A61B5/686 ,  A61B2562/0285 ,  A61B2562/066 ,  A61B2562/12 ,  A61B2562/223 ,  B01J2219/00509 ,  B01J2219/0052 ,  B01J2219/00531 ,  B82Y30/00 ,  B82Y40/00 ,  G01N21/658

Abstract: Methods and systems for nanopillar sensors are described. Nanopillars can be defined on a substrate, and metal deposited on the nanopillars. A thermal treatment can reflow the metal on the nanopillars forming metallic bulbs on the top end of the nanopillars. These structures can have enhanced optical detection when functionalized with biological agents, or can detect gases, particles and liquids through interaction with the metal layer on the nanopillars.

公开(公告)号：US09966443B2

公开(公告)日：2018-05-08

申请号：US14720473

申请日：2015-05-22

Applicant: CALIFORNIA INSTITUTE OF TECHNOLOGY ,  SANOFI

Inventor： Aditya Rajagopal ,  Chieh-feng Chang ,  Oliver Plettenburg ,  Stefan Petry ,  Axel Scherer ,  Charles L. Tschirhart

IPC: H01L29/00 ,  H01L29/41 ,  H01L29/73 ,  H01L29/78 ,  B82Y15/00 ,  H01L29/732 ,  H01L29/06 ,  G01N27/414 ,  H01L29/45 ,  H01L29/49 ,  H01L29/735

CPC classification number: H01L29/413 ,  B82Y15/00 ,  G01N27/4145 ,  G01N27/4146 ,  H01L29/0676 ,  H01L29/45 ,  H01L29/49 ,  H01L29/73 ,  H01L29/732 ,  H01L29/735 ,  H01L29/78

Abstract: Systems and methods for molecular sensing are described. Molecular sensors are described which are based on field-effect or bipolar junction transistors. These transistors have a nanopillar with a functionalized layer contacted to either the base or the gate electrode. The functional layer can bind molecules, which causes an electrical signal in the sensor.

公开(公告)号：US09913603B2

公开(公告)日：2018-03-13

申请号：US14621286

申请日：2015-02-12

Applicant: CALIFORNIA INSTITUTE OF TECHNOLOGY ,  THE REGENTS OF THE UNIVERSITY OF CALIFORNIA ,  UNIVERSITY OF SOUTHERN CALIFORNIA

Inventor： Sameer Walavalkar ,  Chieh-feng Chang ,  Axel Scherer ,  Brandon Marin ,  Scott E. Fraser ,  Andrea R. Tao

IPC: G01N21/65 ,  G01N33/18 ,  G01N33/483 ,  G01N33/00 ,  A61B5/1459 ,  H01L27/146 ,  A61B5/1473 ,  A61B5/07 ,  A61B5/00 ,  B82Y40/00 ,  B82Y30/00

CPC classification number: A61B5/1459 ,  A61B5/0075 ,  A61B5/076 ,  A61B5/14735 ,  A61B5/6848 ,  A61B5/686 ,  A61B2562/0233 ,  A61B2562/0285 ,  A61B2562/12 ,  B82Y30/00 ,  B82Y40/00 ,  G01N21/658 ,  H01L27/14698

Abstract: Methods and systems for nanopillar sensors are described. Nanopillars can be defined on a substrate, and metal deposited on the nanopillars. A thermal treatment can reflow the metal on the nanopillars forming metallic bulbs on the top end of the nanopillars. These structures can have enhanced optical detection when functionalized with biological agents, or can detect gases, particles and liquids through interaction with the metal layer on the nanopillars.

公开(公告)号：US09070733B2

公开(公告)日：2015-06-30

申请号：US13941295

申请日：2013-07-12

Applicant: CALIFORNIA INSTITUTE OF TECHNOLOGY ,  SANOFI

Inventor： Aditya Rajagopal ,  Chieh-feng Chang ,  Oliver Plettenburg ,  Stefan Petry ,  Axel Scherer ,  Charles L. Tschirhart

IPC: H01L29/73 ,  H01L29/78 ,  B82Y15/00 ,  H01L29/732 ,  H01L29/06 ,  H01L29/41 ,  G01N27/414

CPC classification number: H01L29/413 ,  B82Y15/00 ,  G01N27/4145 ,  G01N27/4146 ,  H01L29/0676 ,  H01L29/45 ,  H01L29/49 ,  H01L29/73 ,  H01L29/732 ,  H01L29/735 ,  H01L29/78

Abstract: Systems and methods for molecular sensing are described. Molecular sensors are described which are based on field-effect or bipolar junction transistors. These transistors have a nanopillar with a functionalized layer contacted to either the base or the gate electrode. The functional layer can bind molecules, which causes an electrical signal in the sensor.

Abstract translation: 描述了用于分子感测的系统和方法。 描述了基于场效应或双极结型晶体管的分子传感器。 这些晶体管具有纳米柱，其具有与基极或栅电极接触的官能化层。 功能层可以结合分子，导致传感器中的电信号。