公开(公告)号：US20040239927A1

公开(公告)日：2004-12-02

申请号：US10857706

申请日：2004-05-28

Applicant: Shimadzu Corporation

Inventor： Junki Ishimoto

IPC: G01J003/42

CPC classification number: G01J3/2889 ,  G01J3/10 ,  G01J2003/2836

Abstract: An external signal detection circuit is installed in a new measuring section, and generation and end timing of a readout signal of a spectrometric detector is directly controlled, and a readout signal in synchronization with an external start signal is generated. After input of measurement standby instructions, the external start signal is monitored anytime. Before detection of the external start signal, the new measuring section is shifted to a pause state and after the detection of the external start signal, transition to a measurement state is made. By this configuration, delay time between input time of the external start signal and readout start time of data is defined and valid measurable time at the time of setting short storage time is increased.

Abstract translation: 外部信号检测电路安装在新的测量部分中，直接控制光谱检测器的读出信号的产生和结束定时，并产生与外部起始信号同步的读出信号。 在输入测量待机指令后，随时监控外部启动信号。 在检测到外部启动信号之前，新的测量部分转移到暂停状态，并且在检测到外部启动信号之后，转变到测量状态。 通过该配置，定义外部启动信号的输入时间和数据的读出开始时间之间的延迟时间，并且在设定较短存储时间时有效的可测量时间增加。

公开(公告)号：US20030142305A1

公开(公告)日：2003-07-31

申请号：US10340681

申请日：2003-01-13

Applicant: SHIMADZU CORPORATION

Inventor： Hajime Bungo

IPC: G01J003/42

CPC classification number: G01J3/42 ,  G01J1/44

Abstract: In a spectrophotometer, a photodiode detects light transmitted through a sample in a cell. A pre-amplifier and a feedback resistance are connected to the photodiode to convert a small electric current from the photodiode and amplify a voltage thereof. The voltage is read at a CPU after converted to a digital signal at an A/D converter. A sample component is determined from information based on the signal in the CPU. The spectrophotometer includes a circuit for changing the feedback resistance so that the feedback resistance can be adjusted according to the input voltage to the A/D converter.

Abstract translation: 在分光光度计中，光电二极管检测透过细胞样品的光。 前置放大器和反馈电阻连接到光电二极管以转换来自光电二极管的小电流并放大其电压。 在A / D转换器转换成数字信号后，CPU将读取电压。 基于CPU中的信号的信息确定采样分量。 分光光度计包括用于改变反馈电阻的电路，使得可以根据A / D转换器的输入电压来调整反馈电阻。

公开(公告)号：US20030100102A1

公开(公告)日：2003-05-29

申请号：US10222592

申请日：2002-08-15

Inventor： Jonathan M. Rothberg ,  Joel S. Bader ,  Scott B. Dewell ,  Keith McDade ,  John W. Simpson ,  Jan Berka ,  Christopher M. Colangelo ,  Michael P. Weiner

IPC: C12M001/34 ,  G01J003/42 ,  C12Q001/68

CPC classification number: G01N21/6452 ,  B01L3/5027 ,  B01L3/502715 ,  B01L9/527 ,  B01L2300/0636 ,  B01L2300/0654 ,  B01L2300/0816 ,  B01L2300/0819 ,  B01L2300/0822 ,  B01L2300/0877 ,  B01L2300/0893 ,  B82Y15/00 ,  B82Y30/00 ,  C12P19/34 ,  C12Q1/6827 ,  C12Q1/6837 ,  C12Q1/6869 ,  C12Q1/6874 ,  G01N21/0303 ,  G01N21/7703 ,  C12Q2565/519 ,  C12Q2533/101 ,  C12Q2531/125 ,  C12Q2535/101 ,  C12Q2565/301 ,  C12Q2565/107 ,  C12Q2525/307

Abstract: Disclosed herein are methods and apparatuses for sequencing a nucleic acid. These methods permit a very large number of independent sequencing reactions to be arrayed in parallel, permitting simultaneous sequencing of a very large number (>10,000) of different oligonucleotides.

公开(公告)号：US20030090655A1

公开(公告)日：2003-05-15

申请号：US10290730

申请日：2002-11-07

Inventor： Adam Norton ,  Abdurrahman Sezginer ,  Fred E. Stanke ,  Rodney Smedt

IPC: G01J003/42

CPC classification number: G01J3/02 ,  G01J3/0218 ,  G01J3/08 ,  G01J3/42 ,  G01N21/55

Abstract: The invention is a method and apparatus for determining characteristics of a sample. The system and method provide for detecting a monitor beam reflected off a mirror, where the monitor beam corresponds to the intensity of light incident upon the sample. The system and method also provide for detecting a measurement beam, where the measurement beam has been reflected off the sample being characterized. Both the monitor beam and the measurement beam are transmitted through the same transmission path, and detected by the same detector. Thus, potential sources of variations between the monitor beam and the measurement beam which are not due to the characteristics of the sample are minimized. Reflectivity information for the sample can be determined by comparing data corresponding to the measurement beam relative to data corresponding the monitor beam.

Abstract translation: 本发明是用于确定样品特性的方法和装置。 该系统和方法提供用于检测从反射镜反射的监视光束，其中监视光束对应于入射在样本上的光的强度。 该系统和方法还提供了用于检测测量光束，其中测量光束已经从被表征的样品反射出来。 监测光束和测量光束都通过相同的传输路径传输，并由相同的检测器检测。 因此，监测光束和测量光束之间不是由于样品特性引起的变化的潜在来源被最小化。 可以通过将与测量光束相对应的数据相对于监视光束对应的数据进行比较来确定样本的反射率信息。

公开(公告)号：US20020167663A1

公开(公告)日：2002-11-14

申请号：US10097416

申请日：2002-03-13

Inventor： Anthony Joseph Martino ,  Ken Stephen Schermacher ,  Kelly Regan Smolcynski ,  Michael P. Milone

IPC: G01J003/42

CPC classification number: G01N21/27

Abstract: An apparatus for inspection of fluids, particularly dispersions and tints, having a fluid analysis cell with a cavity therein defining a fluid analysis chamber, fluid inlet and outlets extending from the cavity in opposite directions to enable fluid flow into and out of the analysis chamber, and a light transmitting probe and a light receiving probe extending within the cavity in juxtaposed from each other across the flow path in spaced apart relation, with the probes being movable relative to each other, thus providing a fluid analysis chamber having an adjustable pathlength and allowing flow across and around the faces of the probes for pressure relief of the fluid, to provide accurate color measurements. The apparatus is particularly useful in the manufacture of dispersions and tints used in the manufacture of paints, so that the color of material being made can be accurately matched to a standard color in the wet state with confidence that the color will match in the dry state.

Abstract translation: 用于检查流体，特别是分散体和色调的装置，其具有流体分析单元，其中具有腔体，所述流体分析单元限定流体分析室，流体入口和出口沿相反方向从空腔延伸，以使流体流入和流出分析室， 以及在所述空腔内延伸的光传输探针和光接收探针，其间隔开地跨过所述流动路径彼此并置，所述探针可相对于彼此移动，从而提供具有可调路径长度并允许 流过探针表面并绕其周围流体的压力释放，以提供准确的颜色测量。 该设备在制造用于制造涂料的分散体和着色剂方面特别有用，使得所制造的材料的颜色可以在湿态中准确地与标准颜色匹配，可靠地确定颜色将在干燥状态下匹配 。

公开(公告)号：US20020127706A1

公开(公告)日：2002-09-12

申请号：US10053585

申请日：2002-01-24

Applicant: FUJI PHOTO FILM CO., LTD.

Inventor： Masayuki Naya ,  Takashi Kubo ,  Takashi Ito ,  Yoshimitsu Nomura

IPC: C12M001/34 ,  G01J003/42 ,  G01J003/427

CPC classification number: G01N21/553 ,  B29C45/0025 ,  B29C2045/0027 ,  G01N2201/0415

Abstract: A surface plasmon resonance measuring apparatus is provided with a dielectric block, a metal film formed on a surface of the dielectric block, a light source for emitting a light beam, an optical system for making the light beam enter the dielectric block at various angles of incidence so that a condition for total internal reflection is satisfied at an interface between the dielectric block and the thin film layer, and a photodetector for detecting the intensity of the light beam satisfying total internal reflection at the interface. In the measurement chip to be utilized in the surface plasmon resonance measuring apparatus, the dielectric block is formed from a synthetic resin in which, when said light beam is p-polarized outside said dielectric block and then strikes the interface, the intensity of a s-polarized component at the interface is 50% or less of the intensity of the light beam at the interface.

Abstract translation: 表面等离子体共振测定装置具备介质块，形成在介质块的表面上的金属膜，用于发射光束的光源，使光束以各种角度进入介质块的光学系统 入射，使得在介电块和薄膜层之间的界面处满足全内反射条件，以及用于检测在界面处满足全内反射的光束的强度的光电检测器。 在表面等离子体共振测定装置中使用的测量芯片中，介电块由合成树脂形成，其中当所述光束在所述介质块外部p偏振，然后撞击界面时，s的强度 界面处的极化分量为界面光束强度的50％以下。

公开(公告)号：US20010055115A1

公开(公告)日：2001-12-27

申请号：US09846232

申请日：2001-05-02

Inventor： Theodore M. Garver ,  David G. Jenkins ,  Andrew Riser

IPC: G01J003/42

CPC classification number: G01N21/0303 ,  G01J3/20 ,  G01J3/42 ,  G01N21/031 ,  G01N21/05 ,  G01N21/31 ,  G01N21/33 ,  G01N2021/3129 ,  G01N2021/3133 ,  G01N2021/3137 ,  G01N2021/3155 ,  G01N2021/3185

Abstract: A spectrometer or multiple wavelength absorbance detection method and apparatus providing improved accuracy for an array of measurements at different wavelengths. The spectrometer utilizes a multiple wavelength illumination system with an array of independent detectors with different pathlength cells, where each cell is illuminated with predominately monochromatic light after separation by a light dispersing element. Each sample cell has an optical pathlength, optics and photodetection device that are optimized for its particular wavelength to accurately measure absorbance through an expected substance.

Abstract translation: 一种对不同波长的测量阵列提供改进的精度的光谱仪或多波长吸光度检测方法和装置。 光谱仪利用具有不同光程长度单元的独立检测器阵列的多波长照明系统，其中通过光分散元件分离后，每个单元被主要单色光照射。 每个样品池具有光学长度，光学和光电检测装置，其针对其特定波长进行优化，以通过预期物质精确测量吸光度。

公开(公告)号：US20040233428A1

公开(公告)日：2004-11-25

申请号：US10784595

申请日：2004-02-23

Inventor： Robert H. Hart ,  Montie W. Roland

IPC: G01J003/42

CPC classification number: G01N21/474 ,  G01J1/04 ,  G01J3/02 ,  G01J3/0202 ,  G01J3/0208 ,  G01J3/0229 ,  G01J3/0237 ,  G01J3/0254 ,  G01J3/0278 ,  G01J3/10 ,  G01J3/42 ,  G01J2001/0481 ,  G01N2201/065

Abstract: A spectrophotometric system includes a zoom lens assembly that is mounted for axial translation relative to an integrating sphere. The zoom lens assembly includes first and second focusing lens mounted to an axially movable lens carrier. The lens carrier is positioned intermediate first and second sets of mirrors for reflecting/directing SCE and SCI beams toward fiber ports. A reference beam is also emitted from the integrating sphere and transmitted to a processor, thereby resulting in simultaneous tri-beam measurements. The disclosed spectrophotometric systems may also include an aperture plate detection assembly and/or a sample holder assembly that incorporates a dampening gas spring. The aperture plate detection system includes a detection disk that may include a plurality of pre-positioned sensors that interact with an activating ridge formed on the aperture plate for identification thereof.

Abstract translation: 分光光度系统包括变焦透镜组件，其安装成相对于积分球轴向平移。 变焦透镜组件包括安装到可轴向移动的透镜托架的第一和第二聚焦透镜。 透镜载体位于第一和第二组反射镜之间，用于将SCE和SCI光束反射/导向光纤端口。 参考光束也从积分球发射并传输到处理器，从而导致同时进行三光束测量。 所公开的分光光度系统还可以包括孔板检测组件和/或包含阻尼气弹簧的样品保持器组件。 光圈板检测系统包括检测盘，其可以包括多个预定位传感器，其与形成在孔板上的激活脊相互作用以用于识别。

公开(公告)号：US20040017567A1

公开(公告)日：2004-01-29

申请号：US10169032

申请日：2003-03-11

Inventor： Martin Loicht ,  Andreas Weingartner ,  Wendelin Weingartner ,  Nikolaus Fleischmann ,  Thomas Zipper ,  Bernhard Weingartner

IPC: G01J003/02 ,  G01J003/42

CPC classification number: G01J3/42 ,  G01J3/02 ,  G01J3/0208 ,  G01J3/0227 ,  G01J3/0229 ,  G01J3/0232 ,  G01J3/0256 ,  G01N21/8507 ,  G01N2021/3509

Abstract: The invention concerns a miniaturized spectrometer, especially in the form of a probe, for determination of the ingredients of a gaseous or liquid fluid with a light source (3) and a spectrometer (2), at least one measurement beam and at least one reference beam. The invention is characterized by the fact that the light of the light source (3) is optionally fanned out and bundled by means of at least one optical lens (8) to an essentially parallel beam, that at least one measurement beam is passed through a light transparent window from the probe into the fluid being investigated and through an additional light transparent window back into the probe, that at least one reference beam is guided in the probe interior, that a collecting optics (14), consisting of at least one lens, diverts the beams to the impingement point of the light guide (5) or the inlet of the spectrometer (2), and that a beam selector (7) is provided in the region of the collecting optics (14) that passes through one of the partial beams and interrupts all the others.

Abstract translation: 本发明涉及一种小型化的光谱仪，特别是探针的形式，用于利用光源（3）和光谱仪（2）测定气体或液体流体的成分，至少一个测量光束和至少一个参考 光束。 本发明的特征在于，光源（3）的光可选地被至少一个光学透镜（8）扇出并捆扎成基本平行的光束，使得至少一个测量光束通过 透明窗口，从探针进入被研究的流体，并通过另外的光透明窗口回到探针中，至少一个参考光束在探测器内部被引导，聚集光学器件（14）由至少一个透镜 将光束转移到光导（5）的入射点或光谱仪（2）的入射点，并且在收集光学器件（14）的区域中设置光束选择器（7），该选择器通过 部分光束和所有其他的中断。

公开(公告)号：US20040008346A1

公开(公告)日：2004-01-15

申请号：US10255940

申请日：2002-09-27

Applicant: National Inst. of Advanced Ind. Science and Tech.

Inventor： Etsuo Kawate

IPC: G01J003/42

CPC classification number: G01J3/02 ,  G01J3/0208 ,  G01J3/08 ,  G01N21/41 ,  G01N21/55 ,  G01N21/59 ,  G01N2021/558

Abstract: There is provided an optical system for measurement of optical constant capable of measuring the absolute reflectance and the absolute transmittance for determining the optical constant of a substance with excellent accuracy without replacing the optical system during the measurement by using a different system for measuring the absolute reflectance and the absolute transmittance of the sample, comprising an incoming side beam switching mirror for selectively switching the direction of the light from a light source to a first or second converged light reflecting means side, first and second converged light reflecting means for projecting the light from the beam switching mirror so as to be converged in an intersecting manner at the position of a sample holder, the sample bolder capable of selectively positioning a sample fitting hole or a through hole at the converging position by the converged light reflecting means by advancing/retracting the sample fitting hole or the through hole, first and second received light reflecting means which are disposed on the optical path of the light reflected by or transmitted through a sample set in the sample fitting hole on the sample holder or the through hole, and direct the light toward a single exiting side beam switching mirror, and the exiting side beam switching mirror capable of switching the direction of the light projected via the received light reflecting means toward a single detector, and the absolute reflectance and the absolute transmittance for the face side incidence and the back side incidence of the sample.

Abstract translation: 提供了一种用于测量绝对反射率和绝对透射率的光学常数的光学系统，其用于确定物质的光学常数，而不用在测量期间使用不同的系统来测量绝对反射率 以及样品的绝对透射率，包括用于选择性地将来自光源的光的方向切换到第一或第二会聚光反射装置侧的入射侧光束切换镜，第一和第二会聚光反射装置，用于将光从 所述光束切换镜以在所述样品保持器的位置处相交的方式会聚，所述样品检测器能够通过所述会聚光反射装置通过前进/后退选择性地定位在会聚位置的样品嵌合孔或通孔 样品安装孔或通孔， 第一和第二接收光反射装置，其设置在由样本保持器或通孔上的样本装配孔中反射或透过的样本的光路上，并将光引导到单个离开侧光束切换 反射镜和能够将经由接收的光反射装置投射的光的方向朝向单个检测器切换的出射侧光束切换镜，以及样品的正面入射和背面入射的绝对反射率和绝对透射率 。