公开(公告)号：US20230309907A1

公开(公告)日：2023-10-05

申请号：US18096461

申请日：2023-01-12

Applicant: MASSACHUSETTS INSTITUTE OF TECHNOLOGY

Inventor： Zhongming Li ,  Angela Belcher

IPC: A61B5/00 ,  G01N21/21 ,  G01N21/35 ,  G06T7/00

CPC classification number: A61B5/418 ,  A61B5/0062 ,  A61B5/0082 ,  G01N21/21 ,  G01N21/35 ,  G06T7/0012 ,  G01N2021/3137

Abstract: This disclosure provides a method for imaging lymph nodes and lymphatic vessels without a contrast agent. The method includes providing, using an optical source, an infrared illumination to a region of a subject having at least one lymphatic component, detecting a reflected portion of the infrared illumination directly reflected from the region using a sensor positioned thereabout, and generating at least one image indicative of the at least one lymphatic component in the subject using the reflected portion of the infrared illumination.

公开(公告)号：US10073078B2

公开(公告)日：2018-09-11

申请号：US11889250

申请日：2007-08-10

Applicant: Norimasa Yamamoto ,  Kazutoshi Tokunaga

Inventor： Norimasa Yamamoto ,  Kazutoshi Tokunaga

IPC: G01N33/49 ,  G01N21/31 ,  G01N21/27 ,  G01N21/82 ,  G01N35/02

CPC classification number: G01N33/4905 ,  G01N21/272 ,  G01N21/314 ,  G01N21/82 ,  G01N35/025 ,  G01N2021/3133 ,  G01N2021/3137 ,  G01N2021/3148 ,  G01N2021/3174 ,  G01N2021/825 ,  G01N2201/0618 ,  G01N2201/0826

Abstract: A blood coagulation analyzer and analyzing method perform following: (a) preparing a measurement specimen by dispensing a blood specimen and a reagent into a reaction container; (b) emitting light of a plurality of wavelengths to the measurement specimen in the reaction container, the wavelengths comprising a first wavelength for use in a measurement by a blood coagulation time method, and at least one of a second wavelength for use in a measurement by a synthetic substrate method and a third wavelength for use in a measurement by an immunoturbidimetric method; (c) detecting light of a plurality of wavelengths corresponding to the light emitted in (b), from the measurement specimen, by a light receiving element, and acquiring data corresponding to each wavelength; and (d) conducting an analysis based on the data corresponding to one of the wavelengths among the acquired data, and acquiring a result of the analysis.

公开(公告)号：US20180188158A1

公开(公告)日：2018-07-05

申请号：US15858274

申请日：2017-12-29

Applicant: Nuctech Company Limited

Inventor： Haihui Liu ,  Hongqiu Wang ,  Yumin Yi ,  Jianhong Zhang ,  Ankai Wang

IPC: G01N21/25 ,  G01N21/39

CPC classification number: G01N21/255 ,  G01N21/39 ,  G01N21/4795 ,  G01N21/65 ,  G01N2021/3129 ,  G01N2021/3137 ,  G01N2021/393 ,  G01N2021/399

Abstract: An embodiment of the present disclosure provides a spectrum inspecting apparatus. The apparatus includes a laser source; a focusing cylindrical lens configured to converge a light beam onto a sample; a light beam collecting device configured to collect a light beam signal, which is excited by the light beam, from the sample, so as to form a strip-shaped light spot; a slit configured to receive the collected light beam and couple it to downstream of a light path; a collimating device; a dispersing device configured to disperse the collected light beam so as to form a plurality of sub-beams having different wavelengths; an imaging device configured to image the sub-beams on the photon detector array respectively, wherein the light beam emitted from the laser source has a rectangular cross-section, the strip-shaped light spot impinges on the slit and its length is smaller than a length of the slit.

公开(公告)号：US20180188157A1

公开(公告)日：2018-07-05

申请号：US15740477

申请日：2016-05-25

Applicant: Robert Bosch GmbH

Inventor： Mike Schwarz ,  Thomas Friedrich ,  Timon Brueckner

IPC: G01N21/25 ,  G01N21/3504 ,  G01N21/31 ,  G01N33/00

CPC classification number: G01N21/255 ,  G01J3/36 ,  G01J3/42 ,  G01J2003/1213 ,  G01N21/031 ,  G01N21/314 ,  G01N21/3504 ,  G01N33/004 ,  G01N2021/3137 ,  G01N2021/3166

Abstract: A sensor apparatus having a sensor unit. The sensor unit including pixel assemblages on a substrate upper side of a substrate located on a lower side of the sensor unit; a cap, on the substrate upper side, which covers the pixel assemblages, a cavity being formed between the substrate upper side and the cap; a plurality of filters that are transparent to wavelength regions that differ from one another, exactly one pixel assemblage being associated with each filter; and the filters being on the cap so that the infrared radiation propagated through an absorption gap of the sensor apparatus and the upper side of the sensor unit is detectable, through the respective filter, by the pixel assemblage associated with the respective filter; and a coating made of a light-absorbing and/or light-reflecting material being configured at least locally on a part of the cap which is not covered by the filters.

公开(公告)号：US09709484B2

公开(公告)日：2017-07-18

申请号：US14840516

申请日：2015-08-31

Applicant: Mettler-Toledo AG

Inventor： Tomasz Pol ,  Chun-Hung Kuo ,  William Alan Marks

IPC: G01N21/27 ,  G01N21/31 ,  G01N21/90

CPC classification number: G01N21/276 ,  G01N21/274 ,  G01N21/278 ,  G01N21/31 ,  G01N21/90 ,  G01N2021/3137 ,  G01N2201/061 ,  G01N2201/068 ,  G01N2201/08

Abstract: Apparatuses and methods are disclosed for performing a light-absorption measurement on a test sample and a compliance measurement on a reference sample. A method includes moving a reference sample receptacle carrier of an apparatus to position a first reference sample receptacle received in the carrier at a second position in a light path, directing light from an illumination system to a detection system along the light path to perform a light-absorption measurement on a first reference sample at the second position, moving the carrier to position the first receptacle out of the light path, placing a test sample receptacle in a test sample receptacle holder of the apparatus in the light path at a first position different from the second position, and directing light along the light path to perform a light-absorption measurement on a test sample in the test sample receptacle holder at the first position.

公开(公告)号：US09475334B2

公开(公告)日：2016-10-25

申请号：US14833579

申请日：2015-08-24

Applicant: Spectra Systems Corporation

Inventor： Nabil Lawandy

IPC: G01N21/64 ,  B42D25/36 ,  B42D25/29 ,  G06K7/10 ,  G01N1/22 ,  G01N21/78 ,  G06F21/00 ,  G07D7/12

CPC classification number: B42D25/36 ,  B42D25/29 ,  G01N1/22 ,  G01N21/64 ,  G01N21/6408 ,  G01N21/643 ,  G01N21/783 ,  G01N2021/1795 ,  G01N2021/3137 ,  G01N2021/6417 ,  G01N2021/6419 ,  G01N2021/6439 ,  G06F21/00 ,  G06K7/10544 ,  G07D7/1205

Abstract: Disclosed are security articles and methods and systems for authenticating security articles using a plurality of stimuli. According to one embodiment, an illustrative secured article includes an embedded feature wherein differential activation of phosphorescent or fluorescent materials creates a machine readable response through the simultaneous presence of a source of electromagnetic radiation and a specific gas environment. A detector detects a differential spectral emission across the security feature that results from the change in gas environment. The spectral emission may be compared to an expected emissive signature to determine authenticity of the security article.

Abstract translation: 公开了用于使用多个刺激来认证安全物品的安全物品和方法和系统。 根据一个实施例，说明性的安全物品包括嵌入特征，其中磷光或荧光材料的差分激活通过同时存在电磁辐射源和特定气体环境而产生机器可读响应。 检测器检测由气体环境变化导致的安全特征的差分光谱发射。 可以将光谱发射与期望的发射签名进行比较以确定安全性文章的真实性。

公开(公告)号：US20160187252A1

公开(公告)日：2016-06-30

申请号：US14911365

申请日：2013-10-04

Applicant: HALLIBURTON ENERGY SERVICES INC.

Inventor： Michael T. Pelletier ,  David L. Perkins ,  Li Gao

IPC: G01N21/31 ,  G01V8/00 ,  G01J3/433

CPC classification number: G01N21/31 ,  G01J3/433 ,  G01N21/255 ,  G01N2021/3137 ,  G01N2021/317 ,  G01V8/00

Abstract: A system and method are disclosed for configuring an integrated computational element (ICE) to measure a property of a sample of interest. The system includes an illumination source to provide a sample light which is reflected from or transmitted through a sample. A dispersive element disperses the sample light into wavelength portions. An intensity modulation device having an array of electronically controllable modulation elements is disclosed that forms a pattern which modulates the dispersed sample light. Collection optics focuses the modulated sample light on a detector, which generates a signal that correlates to a property of the sample. The electronically controllable modulation elements can be readily altered to conform to a different measurable property of a sample of interest as desired.

Abstract translation: 公开了一种用于配置集成计算元件（ICE）以测量感兴趣样本的属性的系统和方法。 该系统包括照明源，以提供从样品反射或透射通过样品的样品光。 分散元件将样品光分散成波长部分。 公开了一种具有电子可控调制元件阵列的强度调制装置，其形成调制分散样品光的图案。 采集光学器件将调制的样品光聚焦在检测器上，其产生与样品的性质相关的信号。 可以根据需要容易地改变电子可控调制元件以符合感兴趣样品的不同的可测量性质。

公开(公告)号：US09019501B2

公开(公告)日：2015-04-28

申请号：US13456405

申请日：2012-04-26

Applicant: Robert Freese ,  Christopher Michael Jones ,  David Perkins ,  Michael Simcock ,  William Soltmann

Inventor： Robert Freese ,  Christopher Michael Jones ,  David Perkins ,  Michael Simcock ,  William Soltmann

IPC: G01N21/59 ,  G01N21/17 ,  G01J3/02 ,  G01N21/27 ,  G01N21/31 ,  G06E3/00 ,  G02B5/28 ,  G01J3/12 ,  E21B47/10

CPC classification number: G01N21/17 ,  E21B47/102 ,  G01J3/0229 ,  G01J3/0294 ,  G01J2003/1226 ,  G01N21/274 ,  G01N21/31 ,  G01N2021/3137 ,  G01N2021/3174 ,  G02B5/28 ,  G06E3/001

Abstract: Optical computing devices are disclosed. One exemplary optical computing device includes an electromagnetic radiation source configured to optically interact with a sample and first and second integrated computational elements arranged in primary and reference channels, respectively, the first and second computational elements are configured to be either positively or negatively correlated to the characteristic of the sample. The first and second integrated computational elements produce first and second modified electromagnetic radiations, and a detector is arranged to receive the first and second modified electromagnetic radiations and generate an output signal corresponding to the characteristic of the sample.

Abstract translation: 公开了光学计算设备。 一个示例性光学计算设备包括被配置为与样本光学相互作用的电磁辐射源以及分别布置在主信道和参考信道中的第一和第二集成计算元件，第一和第二计算元件被配置为与 样品的特征。 第一和第二集成计算元件产生第一和第二修改的电磁辐射，并且检测器被布置成接收第一和第二修改的电磁辐射并产生对应于样本的特性的输出信号。

公开(公告)号：US20130284901A1

公开(公告)日：2013-10-31

申请号：US13456443

申请日：2012-04-26

Applicant: Robert Freese ,  Christopher Michael Jones ,  David Perkins ,  Michael Simcock ,  William Soltmann

Inventor： Robert Freese ,  Christopher Michael Jones ,  David Perkins ,  Michael Simcock ,  William Soltmann

IPC: G01N21/17

CPC classification number: G01N21/17 ,  E21B47/123 ,  E21B49/08 ,  G01J2003/1226 ,  G01N21/274 ,  G01N21/31 ,  G01N2021/3137 ,  G01N2021/3174 ,  G06E3/001

Abstract: Optical computing devices are disclosed. One exemplary optical computing device includes an electromagnetic radiation source configured to optically interact with a sample and first and second integrated computational elements arranged in primary and reference channels, respectively, the first and second computational elements are configured to be either positively or negatively correlated to the characteristic of the sample. The first and second integrated computational elements produce first and second modified electromagnetic radiations, and a detector is arranged to receive the first and second modified electromagnetic radiations and generate an output signal corresponding to the characteristic of the sample.

Abstract translation: 公开了光学计算设备。 一个示例性光学计算设备包括被配置为与样本光学相互作用的电磁辐射源以及分别布置在主信道和参考信道中的第一和第二集成计算元件，第一和第二计算元件被配置为与 样品的特征。 第一和第二集成计算元件产生第一和第二修改的电磁辐射，并且检测器被布置成接收第一和第二修改的电磁辐射并产生对应于样本的特性的输出信号。

公开(公告)号：US20130085351A1

公开(公告)日：2013-04-04

申请号：US13701052

申请日：2011-04-28

Applicant: Srinivas Rao Kudavelly ,  Eduard Johannes Meijer

Inventor： Srinivas Rao Kudavelly ,  Eduard Johannes Meijer

IPC: A61B5/1455 ,  A61B5/145

CPC classification number: A61B5/14558 ,  A61B5/0059 ,  A61B5/14546 ,  A61B5/441 ,  A61B2562/0242 ,  G01N21/21 ,  G01N21/31 ,  G01N21/474 ,  G01N2021/215 ,  G01N2021/3137

Abstract: A tissue analyte measuring device (2) includes a light source (4) structured to emit unpolarized light toward the skin surface of a subject, and a detector assembly (8) configured to receive light reflected the skin surface of the subject and the transcutaneous tissues of the subject, the detector assembly including a polarizing filter (12) and a number of light detector subassemblies (14). The polarizing filter is structured to filter out s-polarized light and pass only p-polarized light to light detector subassemblies. The light source is structured and positioned to emit the unpolarized light in a manner wherein the unpolarized light will exit the measuring device at a predetermined angle with respect to a normal to a light emitting plane of the measuring device, wherein the predetermined angle is an angle (the Brewster's angle) at which only s-polarized light will be reflected by the skin surface when the unpolarized light is incident thereon.

Abstract translation: 组织分析物测量装置（2）包括被构造成朝向受试者的皮肤表面发射非偏振光的光源（4），以及检测器组件（8），其被配置为接收被摄体和皮肤组织的皮肤表面反射的光 检测器组件包括偏振滤光器（12）和多个光检测器子组件（14）。 偏振滤光器被构造为滤出s偏振光，并且仅将p偏振光通过光检测器子组件。 光源被构造和定位成以这样的方式发射非偏振光，其中非偏振光将相对于测量装置的发光平面的法线以预定角度离开测量装置，其中预定角度是角度 （布鲁斯特角），当非偏振光入射时，只有s偏振光将被皮肤表面反射。