Urea derivative and process for preparing the same
    6.
    发明授权
    Urea derivative and process for preparing the same 有权
    尿素衍生物及其制备方法

    公开(公告)号:US08058474B2

    公开(公告)日:2011-11-15

    申请号:US12400562

    申请日:2009-03-09

    申请人: Toshihiko Naito

    发明人: Toshihiko Naito

    IPC分类号: C07C275/32 C07C271/58

    CPC分类号: C07D215/233 C07C275/34

    摘要: A process for preparing a compound (C) represented by the following formula: wherein R1 represents hydrogen, C1-6 alkyl or C3-8 cycloalkyl, and R2 represents hydrogen or methoxy, characterized by reacting a compound (A-1) represented by the following formula: wherein R1 has the same definition as above, with a compound (B) represented by the following formula: wherein R2 has the same definition as above, and L represents a leaving group, is provided. Compound (C) is effective for prevention or treatment of various diseases associated with angiogenesis neoplasia.

    摘要翻译: 一种制备由下式表示的化合物(C)的方法:其中R1表示氢,C1-6烷基或C3-8环烷基,R2表示氢或甲氧基,其特征在于使由 下式:其中R 1具有与上述相同的定义,与下式表示的化合物(B):其中R2具有与上述相同的定义,L表示离去基团。 化合物(C)对于预防或治疗与血管生成瘤形成有关的各种疾病是有效的。

    Aminophenol derivatives and their use in cosmetics
    9.
    发明授权
    Aminophenol derivatives and their use in cosmetics 失效
    氨基酚衍生物及其在化妆品中的应用

    公开(公告)号:US06924275B2

    公开(公告)日:2005-08-02

    申请号:US10125411

    申请日:2002-04-19

    摘要: Use of at least one aminophenol derivative of formula (I) below: in which: R represents a hydrogen atom or a radical —COR2,wherein R2 represents a saturated or unsaturated, linear, cyclic or branched, optionally hydroxylated, C1 to C30 hydrocarbon or alkoxy radical;R1 is a radical of formula (a), (b) or (c) below:(a) —CO—NR3R4 (b) —CO—O—R5 (c) —SO2—R5 wherein R3 represents a hydrogen atom or a linear or branched, saturated or unsaturated, optionally hydroxylated, C1 to C4 hydrocarbon radical,R4 represents a hydrogen atom or a saturated or unsaturated, linear, cyclic or branched, optionally hydroxylated, C1 to C30 hydrocarbon radical, andR5 represents a saturated or unsaturated, linear, cyclic or branched, optionally hydroxylated, C1 to C30 hydrocarbon radical,in a depigmenting and/or bleaching cosmetic composition for human skin, body hairs or head hair; compositions comprising the derivatives of formula (I) and a process for depigmenting and/or bleaching the skin, body hairs and/or head hairs.

    摘要翻译: 至少一种式(I)氨基苯酚衍生物的用途如下:其中:R表示氢原子或基团-COR 2,其中R 2表示饱和或 不饱和的,直链的,环状的或支链的,任选羟基化的C 1至C 30烃或烷氧基; R 1是下式(a),(b)或(c)的基团:(a)-CO-NR 3 R 4 (b)-CO-OR 5(c)-SO 2 -R 5其中R 3表示 氢原子或直链或支链,饱和或不饱和的,任选羟基化的C 1至C 4烃基,R 4代表氢 原子或饱和或不饱和的,直链,环状或支链的,任选羟基化的C 1至C 30烃基,R 5表示 饱和或不饱和的,直链的,环状的或支链的,任选羟基化的C 1至C 30烃基,在用于人皮肤的脱色和/或漂白化妆品组合物中,身体毛发 或头发; 包含式(I)的衍生物的组合物和用于脱皮和/或漂白皮肤,身体毛发和/或头发的方法。

    Alkylated urea and triaminotriazine compounds and phase change inks containing same
    10.
    发明申请
    Alkylated urea and triaminotriazine compounds and phase change inks containing same 有权
    烷基化脲和三氨基三嗪化合物和含有它们的相变油墨

    公开(公告)号:US20040249210A1

    公开(公告)日:2004-12-09

    申请号:US10810370

    申请日:2004-03-26

    申请人: Xerox Corporation

    IPC分类号: C07C275/32

    摘要: Compounds of the formulae 1 2 wherein Z is nullOR1, nullSR1, or nullNR1R2, Y is nullOR3, nullSR3, or nullNR3R4, at least one of R1, R2, R3, R4, R5, and R6 is hydrogen, at least one of R1, R2, R3, R4, R5, and R6 is other than hydrogen, at least one Z or Y within the compound is nullNR1R2 or nullNR3R4, R1, R2, R3, R4, R5, R6, and R7 each, independently of the others, is hydrogen, alkyl, aryl, arylalkyl, or alkylaryl, and wherein R7 can also be alkoxy, aryloxy, arylalkyloxy, alkylaryloxy, polyalkyleneoxy, polyaryleneoxy, polyarylalkyleneoxy, polyalkylaryleneoxy, silyl, siloxane, polysilylene, polysiloxane, or 3 wherein X is a direct bond, oxygen, sulfur, nullNR40null wherein R40 is hydrogen, alkyl, aryl, arylalkyl, or alkylaryl, or nullCR50R60null wherein R50 and R60 each, independently of the other, is hydrogen, alkyl, aryl, arylalkyl, or alkylaryl, and wherein R6 can also be 4

    摘要翻译: 下式化合物其中Z为-OR1,-SR1或-NR1R2,Y为-OR3,-SR3或-NR3R4,R 1,R 2,R 3,R 4,R 5和R 6中的至少一个为至少 R1,R2,R3,R4,R5和R6中的一个不是氢,化合物中至少一个Z或Y是-NR1R2或-NR3R4,R1,R2,R3,R4,R5,R6和R7各自 其中R 7也可以是烷氧基,芳氧基,芳烷氧基,烷芳基氧基,聚亚烷基氧基,聚亚芳基氧基,聚芳基亚烷基氧基,聚烷基亚芳基氧基,甲硅烷基,硅氧烷,聚亚芳基,聚硅氧烷,或其中 X是直接键,氧,硫,-NR 40 - ,其中R 40是氢,烷基,芳基,芳基烷基或烷基芳基,或-CR 50 R 60 - 其中R 50和R 60各自独立地是氢,烷基,芳基, ,或烷基芳基,并且其中R6也可以是