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484 条记录 (耗时 0.073 秒)

    Coloring matter, ink, ink for ink jet, ink jet recording method, color toner, and color filter
    6.
    发明授权
    Coloring matter, ink, ink for ink jet, ink jet recording method, color toner, and color filter 有权
    着色剂，油墨，喷墨用墨水，喷墨记录方法，彩色调色剂和滤色器

    公开(公告)号：US08399664B2

    公开(公告)日：2013-03-19

    申请号：US13329466

    申请日：2011-12-19

    申请人： Keiichi Tateishi ,  Yoshiharu Yabuki

    发明人： Keiichi Tateishi ,  Yoshiharu Yabuki

    IPC分类号： C07D403/14 ,  C07D251/52 ,  A61K31/53 ,  C09D11/02 ,  C09B31/143

    CPC分类号： C09B33/12 ,  C07D403/14 ,  C09B29/0037 ,  C09B29/3656 ,  C09B33/24 ,  C09D11/32 ,  C09D11/328 ,  C09D11/40

    摘要： [Problem] To provide a coloring matter which has a good hue, and is capable of forming an image high in fastness property under various use conditions and environmental conditions, and particularly suitable for an ink.[Solving Means] A coloring matter represented by the following formula (I): wherein in the formula, G represents a heterocyclic group, and n represents an integer of 1 to 3; when n is 1, R, X, Y, Z, Q, and G each represents a monovalent group; when n is 2, R, X, Y, Z, Q, and G each represents a monovalent or divalent substituent, provided that at least one represents a divalent substituent; and when n is 3, R, X, Y, Z, Q, and G each represents a monovalent, divalent or trivalent substituent, provided that at least two each represents a divalent substituent, or at least one represents a trivalent substituent.

    摘要翻译： 提供一种具有良好色调的色素，能够在各种使用条件和环境条件下形成坚牢度高的图像，特别适用于油墨。 [解决方案]由下式（I）表示的着色剂：其中，式中，G表示杂环基，n表示1〜3的整数， 当n为1时，R，X，Y，Z，Q和G各自表示一价基团; 当n为2时，R，X，Y，Z，Q和G各自表示一价或二价取代基，条件是至少一个表示二价取代基; 当n为3时，R，X，Y，Z，Q和G各自表示一价，二价或三价取代基，条件是至少两个表示二价取代基，或至少一个表示三价取代基。

    Adsorbents for protein purification
    8.
    发明授权
    Adsorbents for protein purification 有权
    用于蛋白质纯化的吸附剂

    公开(公告)号：US08076477B2

    公开(公告)日：2011-12-13

    申请号：US12281346

    申请日：2007-03-02

    申请人： Jason Richard Betley ,  Helen Tatton ,  Kelly Le Riche ,  Matthew Webb

    发明人： Jason Richard Betley ,  Helen Tatton ,  Kelly Le Riche ,  Matthew Webb

    IPC分类号： C07D251/46 ,  C07D251/52 ,  C07D251/54 ,  C07D251/38 ,  C07D251/30 ,  A61K31/53 ,  B01J20/22 ,  G01N30/00

    CPC分类号： C07D251/48 ,  B01D15/3804 ,  B01J20/286 ,  B01J20/3251 ,  B01J20/3255 ,  Y10T436/25375 ,  Y10T436/255

    摘要： Use of an affinity adsorbent for the separation, removal, isolation, purification, characterisation, identification or quantification of a proteinaceous material, wherein the affinity adsorbent is a compound of formula (III), wherein R1 is H, alkyl, aryl, hydroxyalkyl, cyciohexyl, amino or a heterocyclic group which is optionally substituted with one or more of alkyl, aryl, alkoxy, aryloxy, acyloxy, acylamino, amino, OH, CO2H, sulphonyl, carbamoyl, sulphamoyl, alkylsuiphonyl and halogen; one X is N and the other is N, C—Cl or C—CN; Y is O, S or NR2; Z is O, S or NR3; R2 and R3 are each H, alkyl, hydroxyalkyl, benzyl or β-phenylethyl; Q is benzene, naphthalene, benzthiazole, benzoxazole, 1-phenylpyrazole, indazoie or benzimidazoie; R4, R5 and R6 are each H, OH, alkyl, aryl, heterocyclic, alkoxy, aryloxy, amino, acyloxy, acylamino, CO2H, sulphonic acid, carbamoyl, suiphamoyl, alkylsulphonyl or halogen, or two or more of R4, R5 and R6 are linked to form a cyclic structure; U and V are the same or different C1-10 straight-chain alkylene groups optionally substituted by one or more of hydroxyl, alkyl, aryl, hydroxyl, alkyl, β-phenylethyl and halogen; and A is a support matrix optionally linked to the X-containing ring by a spacer.

    摘要翻译： 使用亲和吸附剂来分离，去除，分离，纯化，表征，鉴定或定量蛋白质物质，其中亲和吸附剂是式（III）化合物，其中R 1是H，烷基，芳基，羟基烷基，环己基 氨基或杂环基，其任选被一个或多个烷基，芳基，烷氧基，芳氧基，酰氧基，酰氨基，氨基，OH，CO 2 H，磺酰基，氨基甲酰基，氨磺酰基，烷基磺酰基和卤素取代; 一个X为N，另一个为N，C-Cl或C-CN; Y是O，S或NR2; Z是O，S或NR 3; R 2和R 3各自为H，烷基，羟基烷基，苄基或苯乙基; Q是苯，萘，苯并噻唑，苯并恶唑，1-苯基吡唑，indazoie或苯并咪唑; R4，R5和R6各自为H，OH，烷基，芳基，杂环，烷氧基，芳氧基，氨基，酰氧基，酰氨基，CO2H，磺酸，氨基甲酰基，磺酰基，烷基磺酰基或卤素，或R4，R5和R6中的两个或多个 连接形成环状结构; U和V是相同或不同的任选被羟基，烷基，芳基，羟基，烷基，苯基乙基和卤素中的一个或多个取代的C 1-10直链亚烷基; 并且A是通过间隔物任选地连接到含X环的支撑基体。

    NOVEL sEH INHIBITORS AND THEIR USE
    9.
    发明申请
    NOVEL sEH INHIBITORS AND THEIR USE 有权
    新型抑制剂及其用途

    公开(公告)号：US20100210656A1

    公开(公告)日：2010-08-19

    申请号：US12682073

    申请日：2008-10-10

    申请人： Yun Ding ,  Reema K. Thalji ,  Joseph P. Marino, JR.

    发明人： Yun Ding ,  Reema K. Thalji ,  Joseph P. Marino, JR.

    IPC分类号： A61K31/53 ,  C07D401/04 ,  C07D251/18 ,  C07D409/04 ,  C07D401/12 ,  C07D401/14 ,  C07D403/04 ,  C07D251/52 ,  A61P9/10 ,  A61P9/00 ,  A61P9/04 ,  A61P11/06 ,  A61P11/00 ,  A61P3/10 ,  A61P3/04

    CPC分类号： C07D241/46 ,  C07D251/18 ,  C07D251/52 ,  C07D401/04 ,  C07D401/12 ,  C07D401/14 ,  C07D403/12 ,  C07D409/04

    摘要： The invention is directed to novel sEH inhibitors and their use in the treatment of diseases mediated by the sEH enzyme. Specifically, the invention is directed to compounds according to Formula I: wherein R1, R2, R4, R5, R6, A, B, Y, Z, n, and m are defined below, and to pharmaceutically-acceptable salts thereof. The compounds of the invention are sEH inhibitors and can be used in the treatment of diseases mediated by the sEH enzyme, such as hypertension. Accordingly, the invention is further directed to pharmaceutical compositions comprising a compound of the invention. The invention is still further directed to methods of inhibiting sEH and treatment of conditions associated therewith using a compound of the invention or a pharmaceutical composition comprising a compound of the invention.

    摘要翻译： 本发明涉及新型sEH抑制剂及其在治疗由sEH酶介导的疾病中的用途。 具体地，本发明涉及式I化合物：其中R1，R2，R4，R5，R6，A，B，Y，Z，n和m定义如下，及其药学上可接受的盐。 本发明的化合物是sEH抑制剂，可用于治疗由sEH酶介导的疾病，例如高血压。 因此，本发明进一步涉及包含本发明化合物的药物组合物。 本发明还涉及使用本发明化合物或包含本发明化合物的药物组合物来抑制sEH和与之相关的病症的治疗方法。

    Azo compounds
    10.
    发明申请
    Azo compounds 失效
    偶氮化合物

    公开(公告)号：US20100151212A1

    公开(公告)日：2010-06-17

    申请号：US11989578

    申请日：2006-07-24

    申请人： Gavin Wright

    发明人： Gavin Wright

    IPC分类号： B32B3/00 ,  C07D251/52 ,  C09D11/00 ,  B05D5/00 ,  B41J2/175

    CPC分类号： C09D11/328 ,  C09B43/16 ,  Y10T428/24802

    摘要： A compound of Formula (1) or a salt thereof: wherein: A1 is optionally substituted phenyl; A2 is optionally substituted aryl; Q1 and Q2 are each independently an optionally substituted phenylene ring which is para connected to the —N═N— and the —NR— groups shown in Formula (1); and each R independently is H or a substituent; with the provisos that: (i) the compound of Formula (1) has at least one group selected from —SO3H and —PO3H2 groups; (ii) the compound of Formula (1) has more groups selected from —SO3H and —PO3H2 groups than the total number of —CO2H and —COSH groups; and (iii) the compound of Formula (1) is not of Formula (1a): The compounds are particularly useful as colorants for use in ink jet printing inks.

    摘要翻译： 式（1）的化合物或其盐：其中：A1为任选取代的苯基; A2是任选取代的芳基; Q1和Q2各自独立地为与式（1）所示的-N = N-和-NR-基团连接的任选取代的亚苯基环; 每个R独立地为H或取代基; 条件是：（i）式（1）的化合物具有至少一个选自-SO 3 H和-PO 3 H 2基团的基团; （ⅱ）式（1）化合物具有比-CO 2 H和-COSH基团更多的选自-SO 3 H和-PO 3 H 2基团的基团; 和（iii）式（1）的化合物不具有式（1a）：该化合物特别可用作用于喷墨印刷油墨的着色剂。