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    Reducing false counts in condensation particle counters
    2.
    发明授权
    Reducing false counts in condensation particle counters 有权

    公开(公告)号：US11879824B2

    公开(公告)日：2024-01-23

    申请号：US17388915

    申请日：2021-07-29

    申请人： TSI Incorporated

    发明人： Richard Remiarz ,  Kenneth Farmer

    IPC分类号： G01N15/06 ,  G01N15/14 ,  G01N15/10 ,  G01N35/00

    CPC分类号： G01N15/065 ,  G01N15/14 ,  G01N2015/1062 ,  G01N2015/1486 ,  G01N2015/1488 ,  G01N2035/00653

    摘要： Various embodiments include methods and apparatuses to reduce false-particle counts in a water-based condensation particle counter (CPC). In one embodiment, a cleanroom CPC has three parallel growth tube assemblies. A detector is coupled to an outlet of each of the three parallel growth tube assemblies, and is used to compare the particle concentrations measured from each of the three growth tube assemblies with remaining ones of the three growth tube assemblies. An algorithm compares the counts from the three detectors and determines when the particles counted are real and when they are false counts. Any real particle event shows up in all three detectors, while false counts will only be detected by one detector. Statistics are used to determine at which particle count levels the measured counts are considered to be real versus false. Other methods and apparatuses are disclosed.

    DEVICES AND METHODS FOR FRACTIONATED PHOTOACOUSTIC FLOW CYTOMETRY
    8.
    发明申请
    DEVICES AND METHODS FOR FRACTIONATED PHOTOACOUSTIC FLOW CYTOMETRY 审中-公开

    公开(公告)号：US20180000351A1

    公开(公告)日：2018-01-04

    申请号：US15541264

    申请日：2015-12-31

    申请人： BioVentures, LLC

    发明人： Vladimir Pavlovich Zharov

    IPC分类号： A61B5/00 ,  A61B8/00 ,  G01N15/10 ,  G01N15/14

    CPC分类号： A61B5/0095 ,  A61B8/4461 ,  A61B8/4477 ,  A61B2560/04 ,  A61B2562/0204 ,  G01N15/1056 ,  G01N15/1434 ,  G01N15/1459 ,  G01N15/1463 ,  G01N15/1475 ,  G01N2015/1006 ,  G01N2015/1062 ,  G01N2015/1075 ,  G01N2015/1438 ,  G01N2015/1477

    摘要： A fractionated photoacoustic flow cytometry (PAFC) system and methods for the in vivo detection of target objects in biofluidic systems (e.g., blood, lymph, urine, or cerebrospinal fluid) of a living organism is described. The fractionated system includes a fractionated laser system, a fractionated optical system, a fractionated acoustic system, and combinations thereof. The fractionated laser system includes at least one laser or laser array for pulsing a target object within the circulatory vessel with fractionated focused laser beams. The fractionated optical system separates one or several laser beams into multiple beams in a spatial configuration on the skin above the circulatory vessel of the living organism. The fractionated acoustic system includes multiple focused ultrasound transducers for receiving photoacoustic signals emitted by the target object in response to the fractionated laser beams. The target objects have intrinsic photoacoustic contrast or may be labeled with photoswitchable or spaser-based probes. Fractioned beams may be used also for diagnostics with other spectroscopic methods (e.g., fluorescence, Raman or scattering) and energy sources both coherent and conventional such as lamp and LED in the broad spectral range from 10 Å to 1 cm (e.g., X-ray, UV, visible, NIR or microwaves) in continuous wave and pulse modes.