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公开(公告)号：US20190119615A1
公开(公告)日：2019-04-25
申请号：US16230036
申请日：2018-12-21
发明人： Martin Anthony Gross , Zhiyou Wen
摘要： An algal growth system can include a frame and a flexible sheet material that can have a substantially vertical orientation, where the flexible sheet material can be configured to facilitate the growth and attachment of algae, where the flexible sheet material can be supported by the frame. The algal growth system can include a first drive shaft, where the first drive shaft can be coupled with the frame, where the first drive shaft can support and actuate the flexible sheet material, a gear system, where the gear system can be coupled with the first drive shaft, a first roller, where the first roller can be coupled with the frame and can be configured to guide the flexible sheet material, and a drive motor, where the drive motor can be coupled with the gear system, where the drive motor can actuate the gear system and the at least one drive shaft such that the flexible sheet material can be actuated.
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公开(公告)号：US20180187139A1
公开(公告)日：2018-07-05
申请号：US15578635
申请日：2016-10-04
CPC分类号： C12M27/14 , C12M23/40 , C12M25/06 , C12M27/20 , C12M41/14 , C12M41/26 , C12M41/32 , C12M41/40 , C12M41/42
摘要： The present invention relates to bioreactor system and method thereof wherein support matrix (2) comprises at last one central shaft and plurality of peripheral shaft being radially surrounds central shaft. Arrays of discs (11) are mounted along the shaft by defining interspatial vicinities between two successive plates. Thus, discs mounted on peripheral shafts are rotated within the interspatial vicinity of discs of central shaft to ensures sufficient mixing and avoid stagnant fluidic zones which is created when discs are mounted closely apart from each other on shafts. Further, plurality of deflector vanes that are axially provided along the length of the central shaft to redirect substantially co-axial direction fluid flow into interior of culture vessel and more specifically towards the central axis. Thus, bioreactor system provides scalable and disposable bioreactor with efficient mixing and homogeneous conditions and thereby supports high density growth and maintenance of cells and other biological material.
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公开(公告)号：US09695392B2
公开(公告)日：2017-07-04
申请号：US14958747
申请日：2015-12-03
申请人： Yury Sherman , Michael Sherman , Ilya Alexandrov
发明人： Yury Sherman , Michael Sherman , Ilya Alexandrov
CPC分类号： C12M27/16 , B01F11/0005 , B01F11/0008 , B01F11/0014 , B01F11/0025 , B01F11/0275 , B01F13/0052 , C12M27/14
摘要： An apparatus for substantially horizontally oscillating one or more vessels containing a liquid, a solid, or a mixture thereof that operates to thoroughly disrupt and mix solid and liquid substances in vessels, like test tubes. The apparatus provides superior mixing through oscillation of the vessels both horizontal and vertical directions through the use of one or more springs and rotating mechanical components. The apparatus includes a circular rotating ring having a toothed circumference that rotates horizontally, at least one vessel support having a compartment configured to hold the one or more vessel vessels and a spring attached to the housing and in constant contact with each of the one or more vessel supports.
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公开(公告)号：US20160130548A1
公开(公告)日：2016-05-12
申请号：US14997324
申请日：2016-01-15
发明人： Mark Selker , Timothy Johnston , Barbara Paldus
CPC分类号： C12M27/14 , C12M23/00 , C12M29/00 , C12M29/06 , G01N21/359 , G01N21/552 , G01N21/65 , G01N21/8507
摘要： A composite sensor assembly for monitoring bio-processes which is suitable for use with a polymeric bioprocess vessel or with downstream equipment, and comprises:i) a port comprising a high surface tension thermoplastic having a hollow tubular portion and a base plate portion, the base plate portion being fusibly sealable to the bioreactor vessel at a hole in the wall thereof;ii) a generally opaque polymeric monitoring sensor assembly including electrical, and/or optical measurement components. The sensor assembly tits inside the bore of the hollow tubular portion of the port, and is adhesively retained therein.
摘要翻译： 一种用于监测适用于聚合物生物过程容器或与下游设备的生物过程的复合传感器组件，包括：i）包含具有中空管状部分和底板部分的高表面张力热塑性塑料的端口， 板部分在其壁的孔处易于密封到生物反应器容器; ii）包括电和/或光学测量部件的通常不透明的聚合物监测传感器组件。 传感器组件在端口的中空管状部分的孔内倾斜，并且粘合地保持在其中。
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公开(公告)号：US20150218501A1
公开(公告)日：2015-08-06
申请号：US14429055
申请日：2013-09-13
CPC分类号： C12M23/08 , C12M21/08 , C12M23/22 , C12M23/28 , C12M23/34 , C12M23/38 , C12M23/48 , C12M27/10 , C12M27/14 , C12M29/00 , C12M29/20 , C12M37/00 , C12M37/02 , C12M41/00
摘要： The invention relates to a reactor tank designed as a disposable element having a cover and/or sensor patches readable opto-electronically fixed in the interior, a reactor comprising the reactor tank and reactor tank receiving peripherals, the same comprising a reactor tank holder and optionally an opto-electronic measuring system for reading sensor patches, wherein the reactor tank holder is coupled to a drive unit for generating a rotating-oscillation motion of the reactor tank around the central vertical axis thereof, and also the use of this device for culturing cells and/or microorganisms.
摘要翻译： 本发明涉及一种设计为一次性元件的反应器罐，其具有可光电耦合固定在内部的盖和/或传感器贴片，反应器包括反应器容器和反应器容器接收外围设备，其包括反应器罐保持器和任选地 用于读取传感器贴片的光电测量系统，其中反应器罐保持器联接到驱动单元，用于产生反应器罐围绕其中心垂直轴的旋转振荡运动，并且还使用该装置用于培养细胞 和/或微生物。
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公开(公告)号：US20140315291A1
公开(公告)日：2014-10-23
申请号：US14256896
申请日：2014-04-18
申请人： Superior Ecotech LLC
发明人： Daniel Higgs , Philip Calabrese , Martin Gross
摘要： Generally, culturing systems and methods for making and using culturing systems. Specifically, photobioreactor systems and methods for making and using photobioreactor systems to culture photosynthetic organisms, such as algae.
摘要翻译： 通常，培养系统和制造和使用培养系统的方法。 具体地，光生物反应器系统和用于制造和使用光生物反应器系统培养光合生物体如藻类的方法。
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7.发明申请公开(公告)号：US20100105125A1
公开(公告)日：2010-04-29
申请号：US12605121
申请日：2009-10-23
申请人： John W. Haley, III
发明人： John W. Haley, III
摘要： Systems, apparatuses, and methods are provided for cultivating microorganisms. In one example, a system may include a plurality of containers for cultivating microorganisms therein. Each container may be adapted to contain water and may include media disposed therein and at least partially submerged in the water. The media may be adapted to support microorganisms during cultivation and a concentration of microorganisms supported by the media may be higher than a concentration of microorganisms suspended in the water.
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8.发明授权Bioreactor for growing fungus, plant cell, tissue, organ, hairy roots and plantlet 有权用于生长真菌，植物细胞，组织，器官，毛根和植物的生物反应器公开(公告)号：US07531350B2
公开(公告)日：2009-05-12
申请号：US11109627
申请日：2005-04-20
申请人： Yih-Juh Shiau
发明人： Yih-Juh Shiau
IPC分类号： C12M1/00
摘要： A bioreactor includes a nutrient reservoir, a rotatable culture bed, at least one culture carrier medium, a mist generator and a mist delivery pipe. The nutrient reservoir stores therein a nutrient solution required for the fungus, plant cell, tissue, organ, hairy roots and plantlet. The rotatable culture bed is rotated at a specified speed. The at least one culture medium has thereon the fungus, plant cell, tissue, organ, hairy roots and plantlet and is supported on the rotatable culture bed. The mist generator is used for producing mists of the nutrient solution. The mist delivery pipe delivers therein the mists of the nutrient solution and has a mist-exit port adjusted to a desired level above the culture medium so as to discharge and spray the mists over the fungus, plant cell, tissue, organ, hairy roots and plantlet.
摘要翻译： 生物反应器包括营养储存器，可旋转培养床，至少一种培养载体介质，雾发生器和雾输送管。 营养储器中储存有真菌，植物细胞，组织，器官，毛根和小植物所需的营养液。 旋转培养床以指定的速度旋转。 所述至少一种培养基上具有真菌，植物细胞，组织，器官，毛状根和小植株，并且被支撑在可旋转培养床上。 雾发生器用于生产营养液的雾。 雾化输送管在其中输送营养液的雾，并且具有调节到培养基上方所需水平的雾出口，以便在真菌，植物细胞，组织，器官，毛状根上排出并喷雾雾， 小植物
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公开(公告)号：US20080145926A1
公开(公告)日：2008-06-19
申请号：US11794234
申请日：2005-12-22
申请人： Franz Kugelmann , Paul Hengster , Raimund Margreiter , Bernd Nederlof , Massimo Fini , Ciro Tetta , Thomas Wild , Micaela Yakubovich , Michael Paul , Marco Caronna
发明人： Franz Kugelmann , Paul Hengster , Raimund Margreiter , Bernd Nederlof , Massimo Fini , Ciro Tetta , Thomas Wild , Micaela Yakubovich , Michael Paul , Marco Caronna
IPC分类号： C12M1/08
摘要： This invention relates to a reactor unit with a first chamber and a second chamber, wherein the first chamber is formed by the interior of a housing and wherein the second chamber is formed by the interior of a plurality of hollow fibers arranged in the housing. The hollow fibers are arranged in the housing such that their density in at least one region of the first chamber does not exceed 10 fibers/mm2, based on the cross-sectional area of the first chamber. In accordance with another aspect of the invention it is provided that in the reactor unit two casting compounds are arranged, in which a portion of the hollow fibers is embedded and between which another portion of the hollow fibers extends, wherein the length of at least some or all hollow fibers is at least 0.5% greater than the distance of the casting compounds.
摘要翻译： 本发明涉及具有第一室和第二室的反应器单元，其中第一室由壳体的内部形成，并且其中第二室由布置在壳体中的多个中空纤维的内部形成。 中空纤维布置在壳体中，使得它们在第一腔室的至少一个区域中的密度基于第一腔室的横截面面积不超过10根纤维/ mm 2。 根据本发明的另一方面，提供了在反应器单元中，布置两个铸造化合物，其中中空纤维的一部分被嵌入，并且在另一部分中空纤维之间延伸，其中至少一些中空纤维的长度 或所有中空纤维比铸造化合物的距离大至少0.5％。
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公开(公告)号：US20060270024A1
公开(公告)日：2006-11-30
申请号：US10563372
申请日：2004-07-08
申请人： Christian Uphoff
发明人： Christian Uphoff
IPC分类号： C12M1/00
CPC分类号： C02F3/341 , C02F1/283 , C02F1/288 , C02F3/06 , C02F3/108 , C02F3/348 , C12M21/02 , C12M25/14 , C12M25/16 , C12M27/14 , C12M33/22 , Y02W10/15 , Y02W10/33 , Y02W10/45
摘要： What is disclosed is a bioreactor comprising a strainer basket, inside which a filler body consisting of a porous carrier having a high specific surface area is received. Into this strainer basket a mixture of microorganisms is introduced which preferably includes a proportion of photosynthetically active microorganisms and a proportion of light-emitting microorganisms, so that a photodynamic decomposition of organic substances takes place. In accordance with the invention, the mixture of microorganisms contains a proportion of photocatalytically active nanoparticles.
摘要翻译： 所公开的是包括过滤器篮的生物反应器，其中容纳由具有高比表面积的多孔载体组成的填料体。 引入该过滤器篮中的微生物混合物，其优选包括一定比例的光合活性微生物和一定比例的发光微生物，使得发生有机物质的光动力学分解。 根据本发明，微生物混合物含有一定比例的光催化活性纳米颗粒。
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