公开(公告)号：US12130227B2

公开(公告)日：2024-10-29

申请号：US17064775

申请日：2020-10-07

Applicant: Excelitas Technologies Corp.

Inventor： John Christopher Freitag ,  Theresa Thompson ,  Garth Eliason ,  Jay Pasquantonio

IPC: G01N21/01 ,  A61L2/10 ,  C12M3/00 ,  G01N21/64 ,  B01L3/00 ,  B01L9/00 ,  C12M1/12 ,  G06V20/69

CPC classification number: G01N21/01 ,  A61L2/10 ,  B01L13/02 ,  C12M23/48 ,  B01L3/5085 ,  B01L9/523 ,  B01L2300/0829 ,  C12M37/00 ,  G01N2021/646 ,  G06V20/69

Abstract: A system for irradiating a microplate may include a modular light engine with one or more light emitting devices. The light emitting devices are configured to emit germicidal radiation to irradiate the microplate, which is configured to be positioned below the modular light engine inside a chamber of the microplate irradiation system. In this way, a uniform intensity of germicidal radiation may be output by light emitting devices, resulting in disruption of contaminating nucleic acids present in the microplate.

公开(公告)号：US20240318107A1

公开(公告)日：2024-09-26

申请号：US18578037

申请日：2022-07-11

Applicant: SIGNIFY HOLDING B.V.

Inventor： PETER DEIXLER

IPC: C12M1/00 ,  A01K1/00 ,  C12M1/12 ,  C12M1/26 ,  C12M1/34 ,  C12M1/36

CPC classification number: C12M21/02 ,  A01K1/0047 ,  C12M33/00 ,  C12M37/00 ,  C12M41/06 ,  C12M41/30 ,  C12M41/48

Abstract: The invention provides a lighting system (1000) for indoor microbiome management in an animal residence (200), wherein the lighting system (1000) comprises a light generating device (100), a control system (300), and an input system (305), wherein: the light generating device (100) is configured to generate first device radiation (111), wherein a spectral power distribution of the first device radiation (111) is selected for promoting persistence of the first microbes (7) relative to second microbes, other than the first microbes (7); the input system (305) is configured to receive and/or sense a microbiome influencing parameter and to provide a related input signal to the control system (300): the control system (300) is configured to control the light generating device (100) in dependence of the related input signal.

公开(公告)号：US12023663B2

公开(公告)日：2024-07-02

申请号：US17522341

申请日：2021-11-09

Applicant: Fenwal, Inc.

Inventor： Richard L. West ,  Alexandra Salomon

IPC: B01L3/00 ,  C12M1/00 ,  C12M1/12 ,  C12M3/00

CPC classification number: B01L13/00 ,  B01L3/56 ,  C12M23/14 ,  C12M23/28 ,  C12M23/48 ,  C12M37/00 ,  B01L2200/0647 ,  B01L2300/043 ,  B01L2300/045 ,  B01L2300/123

Abstract: A retaining table for use with a fluid processing system includes a plate having a generally flat top surface with opposed first and second ends and opposed first and second lateral edges for supporting a disposable container, a first retaining structure connected to the plate along the first end, and a second retaining structure connected to the plate along the second end.

公开(公告)号：US20240209304A1

公开(公告)日：2024-06-27

申请号：US18288496

申请日：2022-04-26

Applicant: THRIVE BIOSCIENCE, INC.

Inventor： Alan BLANCHARD

IPC: C12M1/00 ,  C12M1/12

CPC classification number: C12M41/14 ,  C12M37/00

Abstract: A device, method and apparatus for controlling humidity in a cell incubator. The device includes a thermally conductive block having a water exuding surface, an electrical heater attached to the block and receptive of electrical energy to heat the block, at least one fan for blowing gas to be humidified over the surface of the block, at least humidity sensor attached at least downwind of the block, a controllable pump connectable to a source of water for supplying water to the exuding surface of the block and a controller receptive of output signals from the at least one humidity sensor and connected to the pump for controlling the pump based upon the output signals from the at least one humidity sensor to obtain a desired level of humidity.

公开(公告)号：US20240150693A1

公开(公告)日：2024-05-09

申请号：US18277591

申请日：2022-03-08

Applicant: SUMITOMO BAKELITE CO., LTD.

Inventor： Kohta Igarashi

IPC: C12M1/32 ,  C12M1/00 ,  C12M1/12

CPC classification number: C12M23/12 ,  C12M23/20 ,  C12M37/00

Abstract: The invention of the present application provides a sterile container for cell culture that is sufficiently sterilized but sufficiently retains a low cell adsorption property and that easily forms cell aggregates by cell culture. The sterile container for cell culture having a low cell adsorption property of the invention of the present application includes a cell accommodation part which is made of a resin material and is capable of accommodating cells and a liquid culture medium to perform cell culture, in which a coating layer made of a water-soluble resin having a hydrophilic functional group at a side chain is formed on an inner surface of the cell accommodation part, cross-linking is formed in the water-soluble resin itself and between the water-soluble resin and the inner surface of the cell accommodation part, and the container is subjected to a radiation sterilization treatment with an absorbed radiation dose of 20 kGy or more and 45 kGy or less.

公开(公告)号：US20240141277A1

公开(公告)日：2024-05-02

申请号：US18408995

申请日：2024-01-10

Applicant: PHC Holdings Corporation

Inventor： Hiroki HIRAI ,  Nobuo HORIMOTO ,  Kenichi HORIUCHI ,  Kousuke HONDA ,  Taiki OSHIMOTO ,  Yuta SAKAI ,  Kaori YOSHIDA

IPC: C12M1/00 ,  C12M1/12

CPC classification number: C12M31/10 ,  C12M37/00

Abstract: A culture apparatus includes a box and a light emitting diode (LED) module detachably attached to the box and configured to emit an ultraviolet ray inside the box.

公开(公告)号：US20240132822A1

公开(公告)日：2024-04-25

申请号：US18401976

申请日：2024-01-02

Applicant: Terumo Kabushiki Kaisha ,  Terumo BCT, Inc.

Inventor： Masatsugu IGARASHI ,  Thomas J. Felt

IPC: C12M1/12 ,  C12M1/34 ,  C12M3/00

CPC classification number: C12M25/10 ,  C12M23/48 ,  C12M37/00 ,  C12M41/26 ,  C12M41/32 ,  C12M41/34

Abstract: A cell culturing system includes a cell culturing device and a support device. The cell culturing device cultures cells by allowing a culture medium inside circulation flow paths connected to the bioreactor to flow inside the bioreactor. The cell culturing device is connected to the circulation flow paths and includes a waste liquid flow path in order to discard the liquid flowing through the circulation flow paths, and a waste liquid accommodation unit in which the liquid guided from the waste liquid flow path is accommodated. A sampling unit, in which the culture medium that is guided from the circulation flow paths to the waste liquid flow path is collected, is connected to the waste liquid flow path.

公开(公告)号：US11879120B2

公开(公告)日：2024-01-23

申请号：US17490992

申请日：2021-09-30

Applicant: Thrive Bioscience, Inc.

Inventor： Alan Blanchard

IPC: C12M1/12 ,  C12M3/06 ,  C12M1/04 ,  C12M3/00 ,  C12M1/26 ,  C12M1/00 ,  C12M1/34 ,  C12M1/36 ,  C12M3/02

CPC classification number: C12M37/04 ,  C12M3/02 ,  C12M23/06 ,  C12M23/16 ,  C12M23/24 ,  C12M23/28 ,  C12M23/44 ,  C12M23/50 ,  C12M29/00 ,  C12M33/00 ,  C12M37/00 ,  C12M41/14 ,  C12M41/36 ,  C12M41/46 ,  C12M41/48 ,  C12M47/04

Abstract: In some aspects, the invention relates to automated cell culture incubators and their methods of use. In one aspect, the disclosure provides cell culture incubators having an airlock chamber, a storage chamber and/or an internal chamber. In some aspects, the disclosure provides methods for producing autologous mammalian cell cultures.

公开(公告)号：US20230332088A1

公开(公告)日：2023-10-19

申请号：US18211264

申请日：2023-06-18

Applicant: Futrfab Inc.

Inventor： Frederick A. Flitsch

IPC: C12M1/12 ,  A61K39/00 ,  C07K14/005 ,  C12M3/00 ,  C12M3/06 ,  C12M1/00 ,  C12N5/071

CPC classification number: C12M37/04 ,  A61K39/00 ,  C07K14/005 ,  C12M21/08 ,  C12M23/16 ,  C12M25/14 ,  C12M29/04 ,  C12M37/00 ,  C12N5/0697 ,  C12N2510/02 ,  C12N2513/00

Abstract: The present invention provides apparatus and methods for production of tissue structures, organs, vaccines, and antibody products. In some examples, a cleanspace facility may be equipped with fluid interconnections and controls. The fluid interconnections may be located in a primary cleanspace or peripheral to a primary cleanspace. Sterilization may be performed within the primary cleanspace and within the fluid interconnections. In some examples, the facility may include modelling hardware and software, nanotechnology and microelectronic apparatus, and additive manufacturing equipment to print cells and support matrix to allow cells to grow into tissue structures and organs. Novel structures combining various cell types and electronics may be formed with the fabricator. In some examples, advanced vaccine products may be produced entirely within the scalable, sterile, and automated fabricator.

公开(公告)号：US20230303958A1

公开(公告)日：2023-09-28

申请号：US18205184

申请日：2023-06-02

Applicant: Terumo Kabushiki Kaisha

Inventor： Masatsugu IGARASHI

IPC: C12M1/26 ,  G01N1/20 ,  C12M1/12

CPC classification number: C12M33/04 ,  G01N1/2035 ,  C12M37/00 ,  G01N2001/1445

Abstract: A sampling system includes a sensor (for example, a biosensor) that is provided in a sampling channel so as to be in contact with a sample and measures concentrations of predetermined components in the sample, an introduction path that introduces a cleaning liquid to an upstream side of the sensor of the sampling channel, and an air introduction path that is connected to the introduction path and is opened to the atmosphere. The air guided from the air introduction path flows into the sampling channel via the introduction path.