知搜-全球专利检索

  1. 登录
  2. 注册

搜索结果

43 条记录 (耗时 0.028 秒)

    Ionic aqueous solutions comprising charge-stabilized oxygen-containing nanobubbles
    1.
    发明授权
    Ionic aqueous solutions comprising charge-stabilized oxygen-containing nanobubbles 有权
    包含电荷稳定的含氧纳米气泡的离子水溶液

    公开(公告)号：US09512398B2

    公开(公告)日：2016-12-06

    申请号：US13898357

    申请日：2013-05-20

    申请人： Revalesio Corporation

    发明人： Anthony B. Wood ,  Richard L. Watson ,  Gregory J. Archambeau

    IPC分类号： C12N5/071 ,  B01F3/04 ,  A61K33/00 ,  A61K41/00 ,  B01F3/08 ,  B01F7/00 ,  B29B7/40 ,  A61K9/00

    CPC分类号： C12N5/0602 ,  A61K9/0014 ,  A61K9/0073 ,  A61K33/00 ,  A61K41/0004 ,  B01F3/04099 ,  B01F3/04531 ,  B01F3/0807 ,  B01F3/0853 ,  B01F7/00816 ,  B29B7/401

    摘要： Provided are electrokinetically-altered fluids (e.g., gas-enriched (e.g., oxygen-enriched) electrokinetic fluids) comprising an ionic aqueous solution of charge-stabilized gas-containing nanostructures in an amount sufficient to provide, upon contact with a cell, modulation of at least one of cellular membrane potential and cellular membrane conductivity. Further provided are the methods of making the electrokinetically-altered ionic aqueous fluid compositions. Particular aspects provide for regulating or modulating intracellular signal transduction associated by modulation of at least one of cellular membranes, membrane potential, membrane proteins such as membrane receptors, including but not limited to G-Protein Coupled Receptors (GPCR), and intercellular junctions (e.g., tight junctions, gap junctions, zona adherins and desmasomes). Other embodiments include particular methods of producing the electrokinetically-altered fluids. The electrokinetically-altered fluid compositions and methods of producing the fluid include electrokinetically-altered ionic aqueous fluids optionally in the form of solvated electrons stabilized, at least in part, with molecular gas (e.g., oxygen).

    摘要翻译： 提供了电动改变的流体（例如，富氧（例如，富氧）电动流体），其包含电荷稳定的含气体纳米结构的离子水溶液，其量足以在与电池接触时提供调制 细胞膜电位和细胞膜电导率中的至少一种。 进一步提供制备电动改性的离子水性液体组合物的方法。 特定方面提供调节或调节与细胞膜，膜电位，膜蛋白如膜受体（包括但不限于G蛋白偶联受体（GPCR））和细胞间结合（例如，细胞间接合）中的至少一种调节相关的细胞内信号转导。 ，紧密连接处，间隙连接处，扎胶粘合剂和粘胶）。 其它实施方案包括产生电动改变的流体的特定方法。 电动改变的流体组合物和制备流体的方法包括任选以溶剂化电子的形式的电动改变的离子水性流体，至少部分地用分子气体（例如氧）稳定。

    APPARATUS AND METHODS FOR PRODUCING FOAMED MATERIALS
    3.
    发明申请
    APPARATUS AND METHODS FOR PRODUCING FOAMED MATERIALS 审中-公开
    用于生产泡沫材料的装置和方法

    公开(公告)号：US20090236025A1

    公开(公告)日：2009-09-24

    申请号：US12408282

    申请日：2009-03-20

    申请人： Frank Burkus ,  Pascal Laborde ,  Leslie J. Varga

    发明人： Frank Burkus ,  Pascal Laborde ,  Leslie J. Varga

    IPC分类号： B32B37/12 ,  B29C44/34 ,  B01F3/04

    CPC分类号： B29C44/3446 ,  B01F7/00258 ,  B01F7/00425 ,  B29B7/401 ,  B29B7/44 ,  B29B7/603 ,  B29B7/72 ,  B29B7/7404 ,  B29C44/1228 ,  Y10T156/10

    摘要： Apparatus and methods for producing a foamed material. Pressurized gas is introduced into a multiple-component mixture that contains a catalyst-containing component and a crosslinker-containing component. The multiple-component mixture may be directly mixed and combined with the gas in a mixing device. Alternatively, the multiple-component mixture may be combined in a first mixing device and this mixture may be subsequently combined with the gas in a second mixing device. When dispensed onto an application target, the gas entrained in the multiple-component mixture expands to form the foamed material.

    摘要翻译： 用于生产泡沫材料的装置和方法。 将加压气体引入含有含催化剂的组分和含交联剂组分的多组分混合物中。 可以将多组分混合物直接混合并与混合装置中的气体混合。 或者，多组分混合物可以在第一混合装置中组合，并且该混合物可以随后在第二混合装置中与气体组合。 当分配到施加目标上时，夹带在多组分混合物中的气体膨胀以形成泡沫材料。

    Multi-component mixing apparatus
    5.
    发明申请
    Multi-component mixing apparatus 审中-公开
    多组分混合装置

    公开(公告)号：US20080310253A1

    公开(公告)日：2008-12-18

    申请号：US12149660

    申请日：2008-05-06

    申请人： Nobuyuki Hayashi

    发明人： Nobuyuki Hayashi

    IPC分类号： B01F13/08 ,  B01F9/00

    CPC分类号： B01F7/00816 ,  B01F13/0827 ,  B29B7/401

    摘要： When a drive gear (a driving rotary assembly) is actuated and rotates the rotor (a driven rotary assembly), agitator blades rotate and agitate a base compound (a fluid) and a cure agent (a fluid) in an agitation cavity thereby shearing them. This agitation results in the base compound and the cure agent being mixed into a coating material. Furthermore, magnet force is used for giving rotation force to the rotor 50, and therefore any rotation force transmitting member that penetrates a cylindrical assembly is unnecessary. Therefore, such a rotation trouble caused by the fluids that enter into a gap between the transmitting member and the penetration, increases the viscosity therein, and adhere thereto does not occur.

    摘要翻译： 当驱动齿轮（驱动旋转组件）被致动并使转子（从动旋转组件）旋转时，搅拌器叶片旋转并搅动搅拌腔中的基础化合物（流体）和固化剂（流体），从而剪切它们 。 这种搅拌导致将基础化合物和固化剂混合到涂料中。 此外，磁力用于向转子50提供旋转力，因此不需要穿过圆柱形组件的任何旋转力传递部件。 因此，由于进入传递部件和穿透部之间的间隙的流体引起的旋转故障增加了粘度，不会发生粘附。

    ELECTROKINETICALLY-ALTERED FLUIDS COMPRISING CHARGE-STABILIZED GAS-CONTAINING NANOSTRUCTURES
    6.
    发明申请
    ELECTROKINETICALLY-ALTERED FLUIDS COMPRISING CHARGE-STABILIZED GAS-CONTAINING NANOSTRUCTURES 有权
    包含充电稳定性气体纳米结构的电动液态流体

    公开(公告)号：US20130260462A1

    公开(公告)日：2013-10-03

    申请号：US13898357

    申请日：2013-05-20

    申请人： Revalesio Corporation

    发明人： Anthony B. Wood ,  Richard L. Watson ,  Gregory J. Archambeau

    IPC分类号： C12N5/071 ,  B01F3/04

    CPC分类号： C12N5/0602 ,  A61K9/0014 ,  A61K9/0073 ,  A61K33/00 ,  A61K41/0004 ,  B01F3/04099 ,  B01F3/04531 ,  B01F3/0807 ,  B01F3/0853 ,  B01F7/00816 ,  B29B7/401

    摘要： Provided are electrokinetically-altered fluids (e.g., gas-enriched (e.g., oxygen-enriched) electrokinetic fluids) comprising an ionic aqueous solution of charge-stabilized gas-containing nanostructures in an amount sufficient to provide, upon contact with a cell, modulation of at least one of cellular membrane potential and cellular membrane conductivity. Further provided are the methods of making the electrokinetically-altered ionic aqueous fluid compositions. Particular aspects provide for regulating or modulating intracellular signal transduction associated by modulation of at least one of cellular membranes, membrane potential, membrane proteins such as membrane receptors, including but not limited to G-Protein Coupled Receptors (GPCR), and intercellular junctions (e.g., tight junctions, gap junctions, zona adherins and desmasomes). Other embodiments include particular methods of producing the electrokinetically-altered fluids. The electrokinetically-altered fluid compositions and methods of producing the fluid include electrokinetically-altered ionic aqueous fluids optionally in the form of solvated electrons stabilized, at least in part, with molecular gas (e.g., oxygen).

    摘要翻译： 提供了电动改变的流体（例如，富氧（例如，富氧）电动流体），其包含电荷稳定的含气体纳米结构的离子水溶液，其量足以在与电池接触时提供调制 细胞膜电位和细胞膜电导率中的至少一种。 进一步提供制备电动改性的离子水性液体组合物的方法。 特定方面提供调节或调节与细胞膜，膜电位，膜蛋白如膜受体（包括但不限于G蛋白偶联受体（GPCR））和细胞间结合（例如，细胞间接合）中的至少一种调节相关的细胞内信号转导。 ，紧密连接处，间隙连接处，扎胶粘合剂和粘胶）。 其它实施方案包括产生电动改变的流体的特定方法。 电动改变的流体组合物和制备流体的方法包括任选以溶剂化电子的形式的电动改变的离子水性流体，至少部分地用分子气体（例如氧）稳定。

    Highly filled composites of powered fillers and polymer matrix
    8.
    发明申请
    Highly filled composites of powered fillers and polymer matrix 失效
    动力填料和聚合物基体的高填充复合材料

    公开(公告)号：US20020078793A1

    公开(公告)日：2002-06-27

    申请号：US09973347

    申请日：2001-10-05

    发明人： Richard A. Holl ,  Philip L. Lichtenberger ,  Kenneth S. Yao

    IPC分类号： C22C001/00

    CPC分类号： B22F3/227 ,  B01F2013/1086 ,  B01J2219/00094 ,  B22F1/0059 ,  B22F3/20 ,  B22F3/22 ,  B22F2998/00 ,  B29B7/401 ,  B29B7/88 ,  B29B7/90 ,  B29C47/00 ,  B29C47/0019 ,  B29C47/50 ,  B29C67/242 ,  B29C70/58 ,  B29K2021/00 ,  B29K2105/16 ,  B29K2503/04 ,  C08K3/01 ,  C22C32/0094 ,  H01L23/145 ,  H01L2924/0002 ,  H01L2924/3011 ,  H05K1/0306 ,  H05K1/0373 ,  H05K3/022 ,  H05K2201/0209 ,  H01L2924/00

    摘要： Highly filled composite materials, e.g. comprising approximately 60 volume % or greater of finely powdered particles of filler in a polymer matrix, are made by dissolving polymer in a volatilisable solvent, adding filler and forming a homogeneous mixture by high shear mixing. Most solvent is then removed while maintaining homogeneity in the mixture, preferably by evaporation in a high shear mill. Then, extruding a thin layer of the composite material and removing remaining solvent, as by heating. Bodies are formed from the dried layer, which are heated and pressed to melt and disperse melted polymer into the interstices between filler particles. Thereby, certain polymers unusable at low solids contents become effective bonding materials at high solids contents. Filler materials are chosen to tailor electrical and physical properties of the articles, which may comprise substrates for electronic circuits. Suitable polymers are certain polyarylene ethers soluble in cyclohexanone.

    摘要翻译： 高填充复合材料，例如 通过将聚合物溶解在可挥发的溶剂中，加入填料并通过高剪切混合形成均匀的混合物来制备聚合物基体中约60体积％或更多的细粉末填料颗粒。 然后除去大部分溶剂，同时保持混合物中的均匀性，优选通过在高剪切研磨机中蒸发。 然后，通过加热挤出复合材料的薄层并除去剩余的溶剂。 主体由干燥层形成，被加热和压制以熔化并将熔融的聚合物分散到填料颗粒之间的空隙中。 因此，在低固体含量下不能使用的某些聚合物成为高固体含量的有效粘合材料。 选择填充材料来定制物品的电气和物理性质，其可以包括用于电子电路的基底。 合适的聚合物是可溶于环己酮的某些聚亚芳基醚。

    Composites of powdered fillers and polymer matrix
    9.
    发明授权
    Composites of powdered fillers and polymer matrix 有权
    粉末填料和聚合物基体的复合材料

    公开(公告)号：US06391082B1

    公开(公告)日：2002-05-21

    申请号：US09345813

    申请日：1999-07-02

    申请人： Richard A. Holl

    发明人： Richard A. Holl

    IPC分类号： C22C105

    CPC分类号： B22F3/227 ,  B01F2013/1086 ,  B01J2219/00094 ,  B22F1/0074 ,  B22F1/02 ,  B22F3/20 ,  B22F7/04 ,  B22F2998/00 ,  B29B7/401 ,  B29B7/603 ,  B29B7/82 ,  B29B7/845 ,  B29B7/90 ,  B29B13/10 ,  B29C47/00 ,  B29C47/0019 ,  B29C47/50 ,  B29C67/242 ,  B29C70/58 ,  B29K2021/00 ,  B29K2071/00 ,  B29K2105/16 ,  B29K2503/04 ,  C08J3/212 ,  C08J2371/12 ,  C08K3/01 ,  C08L71/12 ,  C22C32/0094 ,  H01L21/4882 ,  H01L23/145 ,  H01L23/293 ,  H01L23/3737 ,  H01L2924/0002 ,  H01L2924/12044 ,  H05K1/0373 ,  H05K3/022 ,  H05K3/14 ,  H05K3/381 ,  H05K2201/0209 ,  H05K2201/0212 ,  H05K2201/0215 ,  H05K2201/0227 ,  H05K2201/0254 ,  H05K2201/068 ,  H05K2201/0792 ,  H05K2201/083 ,  H05K2203/0278 ,  H05K2203/068 ,  H05K2203/1194 ,  Y10T428/12028 ,  H01L2924/00

    摘要： Composite materials comprising at least 60 volume %, preferably 70 volume %, of particles of finely powdered filler material in a matrix of poly(arylene ether) polymer material are made by forming a mixture of the components, forming the required bodies therefrom, and then heating and pressing the bodies to a temperature sufficient to melt the polymer and to a pressure sufficient to disperse the melted polymer into the interstices between the filler particles. Surprisingly these polymer materials can only be effective as bonding materials when the solids content is as high as that specified, since with lower contents the resultant bodies are too friable. This is completely contrary to accepted prior art practice which considers that composites are progressivly weakened as the solids content is increased, so that such content must be limited. In processes to obtain as complete a dispersion of the components as possible they are individually dispersed in a liquid dispersion medium containing the polymer together with necessary additives, each mixture being ground if required to obtain a desired particle size, the mixtures are mixed, again ground to produce thorough dispersion, are separated from the liquid dispersion medium and green articles formed from the resulting pasty mixture. The green articles are then heated and pressed as described above. Mixtures of different filler materials may be used to tailor the electrical and physical properties of the final materials. The articles preferably comprise substrates for use in electronic circuits.

    摘要翻译： 在聚（亚芳基醚）聚合物材料的基体中包含至少60体积％，优选70体积％的细粉末状填料的颗粒的复合材料通过形成组分的混合物制成，从而形成所需体，然后 将物体加热和压制到足以熔化聚合物的温度和足以将熔融的聚合物分散到填料颗粒之间的空隙中的压力。 令人惊讶的是，当固体含量高达规定值时，这些聚合物材料只能作为粘合材料有效，因为所得物体的含量较低，因此太脆。 这完全违背了接受的现有技术实践，认为随着固体含量增加，复合材料逐渐减弱，因此这些内容必须受到限制。 在获得尽可能完整的组分分散体的方法中，它们分别分散在含有聚合物的液体分散介质中以及必要的添加剂，如果需要，每个混合物被研磨以获得所需的粒度，混合物再次混合 从液体分散介质和由所得糊状混合物形成的绿色物品分离，以产生彻底的分散。 然后如上所述加热和按压绿色制品。 可以使用不同填料材料的混合物来定制最终材料的电学和物理性能。 物品优选地包括用于电子电路的基底。

    COMPOSITES OF POWDERED FILLERS AND POLYMER MATRIX
    10.
    发明申请
    COMPOSITES OF POWDERED FILLERS AND POLYMER MATRIX 有权
    粉末填料和聚合物基质的复合材料

    公开(公告)号：US20020038582A1

    公开(公告)日：2002-04-04

    申请号：US09345813

    申请日：1999-07-02

    发明人： RICHARD A. HOLL

    IPC分类号： C22C029/00

    CPC分类号： B22F3/227 ,  B01F2013/1086 ,  B01J2219/00094 ,  B22F1/0074 ,  B22F1/02 ,  B22F3/20 ,  B22F7/04 ,  B22F2998/00 ,  B29B7/401 ,  B29B7/603 ,  B29B7/82 ,  B29B7/845 ,  B29B7/90 ,  B29B13/10 ,  B29C47/00 ,  B29C47/0019 ,  B29C47/50 ,  B29C67/242 ,  B29C70/58 ,  B29K2021/00 ,  B29K2071/00 ,  B29K2105/16 ,  B29K2503/04 ,  C08J3/212 ,  C08J2371/12 ,  C08K3/01 ,  C08L71/12 ,  C22C32/0094 ,  H01L21/4882 ,  H01L23/145 ,  H01L23/293 ,  H01L23/3737 ,  H01L2924/0002 ,  H01L2924/12044 ,  H05K1/0373 ,  H05K3/022 ,  H05K3/14 ,  H05K3/381 ,  H05K2201/0209 ,  H05K2201/0212 ,  H05K2201/0215 ,  H05K2201/0227 ,  H05K2201/0254 ,  H05K2201/068 ,  H05K2201/0792 ,  H05K2201/083 ,  H05K2203/0278 ,  H05K2203/068 ,  H05K2203/1194 ,  Y10T428/12028 ,  H01L2924/00

    摘要： Composite materials comprising at least 60 volume %, preferably 70 volume %, of particles of finely powdered filler material in a matrix of poly(arylene ether) polymer material are made by forming a mixture of the components, forming the required bodies therefrom, and then heating and pressing the bodies to a temperature sufficient to melt the polymer and to a pressure sufficient to disperse the melted polymer into the interstices between the filler particles. Surprisingly these polymer materials can only be effective as bonding materials when the solids content is as high as that specified, since with lower contents the resultant bodies are too friable. This is completely contrary to accepted prior art practice which considers that composites are progressivly weakened as the solids content is increased, so that such content must be limited. In processes to obtain as complete a dispersion of the components as possible they are individually dispersed in a liquid dispersion medium containing the polymer together with necessary additives, each mixture being ground if required to obtain a desired particle size, the mixtures are mixed, again ground to produce thorough dispersion, are separated from the liquid dispersion medium and green articles formed from the resulting pasty mixture. The green articles are then heated and pressed as described above. Mixtures of different filler materials may be used to tailor the electrical and physical properties of the final materials. The articles preferably comprise substrates for use in electronic circuits.

    摘要翻译： 在聚（亚芳基醚）聚合物材料的基体中包含至少60体积％，优选70体积％的细粉末状填料的颗粒的复合材料通过形成组分的混合物制成，从而形成所需体，然后 将物体加热和压制到足以熔化聚合物的温度和足以将熔融的聚合物分散到填料颗粒之间的空隙中的压力。 令人惊讶的是，当固体含量高达规定值时，这些聚合物材料只能作为粘合材料有效，因为所得物体的含量较低，因此太脆。 这完全违背了接受的现有技术实践，认为随着固体含量增加，复合材料逐渐减弱，因此这些内容必须受到限制。 在获得尽可能完整的组分分散体的方法中，它们分别分散在含有聚合物的液体分散介质中以及必要的添加剂，如果需要，每个混合物被研磨以获得所需的粒度，混合物再次混合 从液体分散介质和由所得糊状混合物形成的绿色物品分离，以产生彻底的分散。 然后如上所述加热和按压绿色制品。 可以使用不同填料材料的混合物来定制最终材料的电学和物理性能。 物品优选地包括用于电子电路的基底。