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    ARTICLES AND METHODS INCLUDING STABLE THERMALLY-RESPONSIVE POLYMERS
    5.
    发明申请
    ARTICLES AND METHODS INCLUDING STABLE THERMALLY-RESPONSIVE POLYMERS 审中-公开
    包括稳定的热应答聚合物的文章和方法

    公开(公告)号：US20120183500A1

    公开(公告)日：2012-07-19

    申请号：US13185041

    申请日：2011-07-18

    Applicant: Emily Rose Rolfes Meyering ,  Toni M. Heyer

    Inventor： Emily Rose Rolfes Meyering ,  Toni M. Heyer

    IPC: A61K47/32 ,  B01D57/02 ,  A61K38/02 ,  A61K31/7088 ,  C08F220/60 ,  A61K35/00

    CPC classification number: A61K31/7088 ,  A61L27/16 ,  A61L27/50 ,  A61L27/52 ,  A61L31/048 ,  A61L31/14 ,  A61L31/145 ,  B01D15/34 ,  B01D15/3876 ,  C08L33/26

    Abstract: Embodiments of the invention can include or be used in conjunction with implantable medical devices and various in vitro applications. In an embodiment, an implantable medical device is included herein. The device can include a frame having an inner lumen; the frame comprising a copolymer formed from monomers comprising N-isopropylacrylamide or a thermally responsive derivative thereof and a second monomeric species including one or more of a heteroatom or a charged moiety. In an embodiment, a method of isolating a component of a mixture is included herein. The method can include mixing a sample with a copolymer formed from monomers comprising N-isopropylacrylamide or a thermally responsive derivative thereof and a second monomeric species including one or more of a heteroatom or a charged moiety to form a reagent mixture, the copolymer further comprising a moiety exhibiting affinity for an analyte in the sample. The method can further include raising the temperature of the reagent mixture to high enough for the copolymer to form a hydrogel. Other embodiments are also included herein.

    Abstract translation: 本发明的实施方案可以包括或与可植入医疗装置和各种体外应用结合使用。 在一个实施例中，本文包括可植入医疗装置。 该装置可以包括具有内腔的框架; 该框架包括由包含N-异丙基丙烯酰胺或其热响应衍生物的单体形成的共聚物和包含一个或多个杂原子或带电部分的第二单体种类。 在一个实施方案中，本文包括分离混合物组分的方法。 该方法可以包括将样品与由包含N-异丙基丙烯酰胺或其热响应衍生物的单体形成的共聚物和包含一个或多个杂原子或带电部分的第二单体物质混合以形成试剂混合物，所述共聚物还包含 部分对样品中的分析物表现出亲和力。 该方法可以进一步包括将试剂混合物的温度升高至足以使共聚物形成水凝胶。 本文还包括其它实施例。

    Continuous desalination process
    7.
    发明授权
    Continuous desalination process 失效
    连续脱盐工艺

    公开(公告)号：US4447329A

    公开(公告)日：1984-05-08

    申请号：US503490

    申请日：1983-06-13

    Applicant: Donald B. Broughton

    Inventor： Donald B. Broughton

    IPC: B01D15/18 ,  B01J47/10 ,  B01J49/00 ,  B01D15/04

    CPC classification number: C02F1/42 ,  B01D15/1821 ,  B01J47/105 ,  B01J49/0056 ,  B01D15/203 ,  B01D15/3876 ,  B01D2215/023 ,  C02F2103/08 ,  C02F2209/02 ,  C02F2303/16

    Abstract: A process for the desalination of water in a continuous cyclical adsorptive operation utilizing a thermally regenerable ion retarding resin. The process employs a simulated moving bed scheme having only an adsorption zone, operated at a relatively low temperature, and desorption zone, operated at a relatively high temperature. Effluent is removed from the adsorption zone in two stages for each step of a cycle, a first stage wherein sufficient water is recovered for use as desorbent in the next step, and a second stage wherein the water product stream is withdrawn. Effluent is removed from the desorption zone also in two stages, a first stage wherein a relatively small portion having the composition of the feedstream is withdrawn, and a second stage where the extract stream having a high salt content is withdrawn.

    Abstract translation: 一种利用热可再生离子延迟树脂在连续循环吸附操作中脱盐水的方法。 该方法采用仅在相对较低温度下操作的吸附区和在较高温度下操作的解吸区的模拟移动床方案。 对于循环的每个步骤，将废水从吸附区域分离两个阶段，其中回收足够的水用作下一步骤中的解吸剂的第一阶段，以及第二阶段，其中取出水产物流。 流出物也从两个阶段从解吸区除去，第一阶段其中取出具有进料流组成的相对小的部分，以及第二阶段，其中提取具有高盐含量的萃取物料流。

    PURIFICATION METHOD
    9.
    发明申请
    PURIFICATION METHOD 审中-公开
    净化方法

    公开(公告)号：US20130126409A1

    公开(公告)日：2013-05-23

    申请号：US13671768

    申请日：2012-11-08

    Applicant: Hammersmith Imanet Limited

    Inventor： ERIK ARSTAD

    IPC: B01D15/38

    CPC classification number: B01D15/3876 ,  C07B63/00

    Abstract: The invention relates to methods and apparatus for purifying a radiolabelled compound. The method comprises (i) passing a crude reaction mixture comprising the desired radiolabelled compound and one or more contaminants in a solvent through a narrow bore vessel at elevated temperature such that the organic solvent and either the radiolabelled compound or one or more contaminants is vaporised forming a vaporised component, and (ii) collecting the resulting vaporised component by condensing into a collection vessel.

    Abstract translation: 本发明涉及用于纯化放射性标记化合物的方法和装置。 该方法包括：（i）将包含期望的放射性标记化合物和一种或多种污染物的粗反应混合物在溶剂中通过窄孔容器在升高的温度下通过，使得有机溶剂和放射性标记化合物或一种或多种污染物被蒸发形成 蒸发的组分，和（ii）通过冷凝到收集容器中收集所得蒸发的组分。

    Method for the purification of radiolabelled compounds
    10.
    发明授权
    Method for the purification of radiolabelled compounds 失效
    纯化放射性标记化合物的方法

    公开(公告)号：US08309054B2

    公开(公告)日：2012-11-13

    申请号：US12375555

    申请日：2007-07-25

    Applicant: Erik Arstad

    Inventor： Erik Arstad

    IPC: A61K51/00 ,  A61M36/14

    CPC classification number: B01D15/3876 ,  C07B63/00

    Abstract: The invention relates to methods and apparatus for purifying a radiolabelled compound. The method comprises (i) passing a crude reaction mixture comprising the desired radiolabelled compound and one or more contaminants in a solvent through a narrow bore vessel at elevated temperature such that the organic solvent and either the radiolabelled compound or one or more contaminants is vaporised forming a vaporised component, and (ii) collecting the resulting vaporised component by condensing into a collection vessel.

    Abstract translation: 本发明涉及用于纯化放射性标记化合物的方法和装置。 该方法包括：（i）将包含期望的放射性标记化合物和一种或多种污染物的粗反应混合物在溶剂中通过窄孔容器在升高的温度下通过，使得有机溶剂和放射性标记化合物或一种或多种污染物被蒸发形成 蒸发的组分，和（ii）通过冷凝到收集容器中收集所得蒸发的组分。

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