公开(公告)号：US09072824B2

公开(公告)日：2015-07-07

申请号：US13446046

申请日：2012-04-13

Applicant: Christopher D. Gassman ,  Andres Pasko ,  Walter T. Watts

Inventor： Christopher D. Gassman ,  Andres Pasko ,  Walter T. Watts

IPC: A61M1/00 ,  F17D3/00 ,  A61M1/02 ,  A61M5/148 ,  A61M5/14 ,  A61M39/14

CPC classification number: A61M1/02 ,  A61M1/0209 ,  A61M1/0218 ,  A61M1/0272 ,  A61M1/0281 ,  A61M1/029 ,  A61M5/1417 ,  A61M5/1486 ,  A61M39/143 ,  A61M2205/15 ,  A61M2205/331 ,  A61M2205/3331 ,  A61M2209/084 ,  Y10T137/0318 ,  Y10T137/8593

Abstract: A system is provided for controlling fluid flow in a flow circuit of the type including at least two flexible containers which are fluidly connected by a conduit. The system includes a pressure chamber having an interior which receives one of the containers of the flow circuit. The pressure chamber has at least one port which communicates between the interior of the pressure chamber and the outside environment and receives at least a portion of the conduit of the flow circuit. The pressure chamber also includes a pressure/vacuum source for increasing the pressure in the interior of the pressure chamber above atmospheric pressure and decreasing the pressure in the interior of the pressure chamber below atmospheric pressure. The pressure chamber may include other elements, such as interface detectors, clamping devices, sealing devices, and access devices for automatically processing fluid, such as separated blood.

Abstract translation: 提供了一种系统，用于控制流动回路中的流体流动，所述流动回路包括通过导管流体连接的至少两个柔性容器。 该系统包括具有内部的压力室，该内部容纳流动回路的容器之一。 压力室具有至少一个在压力室的内部与外部环境之间连通的端口，并且接收流动回路的导管的至少一部分。 压力室还包括压力/真空源，用于增加压力室内部的压力高于大气压力并且将压力室内的压力降低到大气压以下。 压力室可以包括诸如界面检测器，夹紧装置，密封装置和用于自动处理诸如分离的血液之类的流体的进入装置的其它元件。

公开(公告)号：US08702129B2

公开(公告)日：2014-04-22

申请号：US12597126

申请日：2008-04-23

Applicant: Arnold C. Bilstad ,  Bradley H. Buchanan ,  T. Michael Dennehey ,  Michael E. Goodwin ,  Jeremy K. Larsen ,  Whitt F. Woods ,  David V. Bacehowski

Inventor： Arnold C. Bilstad ,  Bradley H. Buchanan ,  T. Michael Dennehey ,  Michael E. Goodwin ,  Jeremy K. Larsen ,  Whitt F. Woods ,  David V. Bacehowski

IPC: F16L35/00

CPC classification number: A61M39/143 ,  A61M39/12 ,  A61M39/16 ,  B29C65/02 ,  B29C65/06 ,  B29C65/08 ,  B29C65/1412 ,  B29C65/1435 ,  B29C65/1441 ,  B29C65/1445 ,  B29C65/1467 ,  B29C65/148 ,  B29C65/16 ,  B29C65/48 ,  B29C65/7473 ,  B29C66/0242 ,  B29C66/1142 ,  B29C66/1162 ,  B29C66/322 ,  B29C66/5221 ,  B29C66/5223 ,  B29C66/5229 ,  B29C66/52293 ,  B29C66/52297 ,  B29C66/52298 ,  B29C66/534 ,  B29C66/54 ,  B29C66/71 ,  B29C66/73921 ,  B29C66/80 ,  B29C66/81267 ,  B29K2027/16 ,  B29K2101/12 ,  B29K2995/0025 ,  B29K2995/0026 ,  F16L29/005 ,  F16L2201/44 ,  B29K2071/00 ,  B29K2069/00 ,  B29K2033/12 ,  B29K2033/08 ,  B29K2027/12

Abstract: A system for forming a fluid connection includes a first connector and a second connector. Both connectors include a tubular body having a membrane mounted on a distal end thereof. A support member facilitates the coupling of the connectors together so that the membranes are abutted together. Radiant energy is applied to the abutted membranes so as to first sterilize the membranes and then melt the membranes so that a passage is formed therethrough.

Abstract translation: 用于形成流体连接的系统包括第一连接器和第二连接器。 两个连接器包括具有安装在其远端上的膜的管状体。 支撑构件便于将连接器耦合在一起，使得膜抵靠在一起。 将辐射能量施加到邻接的膜上，以便首先对膜进行灭菌，然后熔化膜，使得通过其形成通道。

公开(公告)号：US20100133807A1

公开(公告)日：2010-06-03

申请号：US12597126

申请日：2008-04-23

Applicant: Arnold C. Bilstad ,  Bradley H. Buchanan ,  T. Michael Dennehey ,  Michael E. Goodwin ,  Jeremy K. Larsen ,  Whitt F. Woods ,  David V. Bacehowski

Inventor： Arnold C. Bilstad ,  Bradley H. Buchanan ,  T. Michael Dennehey ,  Michael E. Goodwin ,  Jeremy K. Larsen ,  Whitt F. Woods ,  David V. Bacehowski

IPC: F16L55/00

CPC classification number: A61M39/143 ,  A61M39/12 ,  A61M39/16 ,  B29C65/02 ,  B29C65/06 ,  B29C65/08 ,  B29C65/1412 ,  B29C65/1435 ,  B29C65/1441 ,  B29C65/1445 ,  B29C65/1467 ,  B29C65/148 ,  B29C65/16 ,  B29C65/48 ,  B29C65/7473 ,  B29C66/0242 ,  B29C66/1142 ,  B29C66/1162 ,  B29C66/322 ,  B29C66/5221 ,  B29C66/5223 ,  B29C66/5229 ,  B29C66/52293 ,  B29C66/52297 ,  B29C66/52298 ,  B29C66/534 ,  B29C66/54 ,  B29C66/71 ,  B29C66/73921 ,  B29C66/80 ,  B29C66/81267 ,  B29K2027/16 ,  B29K2101/12 ,  B29K2995/0025 ,  B29K2995/0026 ,  F16L29/005 ,  F16L2201/44 ,  B29K2071/00 ,  B29K2069/00 ,  B29K2033/12 ,  B29K2033/08 ,  B29K2027/12

Abstract: A system for forming a fluid connection includes a first connector (12) and a second connector (14). Both connectors include a tubular body (18,18′) having a membrane (19,19′) mounted on a distal end (27) thereof. A support member (16) or other fastener (214,220) facilitates the coupling of the connectors together so that the membranes are abutted together. Radiant or other form of energy is applied to the abutted membranes so as to sterilize the membranes and melt the membranes so that a passage is formed therethrough.

Abstract translation: 用于形成流体连接的系统包括第一连接器（12）和第二连接器（14）。 两个连接器包括具有安装在其远端（27）上的膜（19,19'）的管状体（18,18'）。 支撑构件（16）或其它紧固件（214,220）有助于将连接器耦合在一起，使得膜抵靠在一起。 将辐射或其他形式的能量施加到邻接的膜上，以便对膜进行灭菌并熔化膜，使得通过其形成通道。

公开(公告)号：US06696018B2

公开(公告)日：2004-02-24

申请号：US09993367

申请日：2001-11-14

Applicant: Brad Buchanan

Inventor： Brad Buchanan

IPC: A61L200

CPC classification number: A61L2/082 ,  A61L2/087 ,  A61L2/14 ,  A61L2/26 ,  A61L2202/122 ,  A61M39/143 ,  A61M39/16 ,  A61M39/18 ,  B29C65/56 ,  B29C65/565 ,  B29C65/7802 ,  B29C66/001 ,  B29C66/1122 ,  B29C66/522 ,  B29C66/5221 ,  B29C66/5223 ,  B29C66/52291 ,  B29C66/52293 ,  B29C66/52297 ,  B29C66/71 ,  B29C66/8221 ,  B29C66/8222 ,  B29C66/8225 ,  B29C66/83241 ,  B29L2023/007 ,  F16L33/00 ,  B29K2023/06 ,  B29K2023/12 ,  B29K2027/06 ,  B29K2027/16 ,  B29K2027/18 ,  B29K2075/00 ,  B29K2077/00 ,  B29K2083/00

Abstract: A sterilization system seals a first end portion of a first tube and a second end portion of a second tube under sterile conditions. The sterilization system includes a sterilization chamber and an electron gun which generates a distribution of electrons in the sterilization chamber. The sterilization system further includes a spindle and a holder which places and rotates a connector in the distribution of electrons. The sterilization system further includes first and second tube holders each having curved walls movably coupled to the sterilization chamber to move between a first position where the respective end portion is separated from the connector and a second position where the respective end portion is coupled to the connector. Each curved wall has a shape such that x rays generated within the sterilization chamber undergo at least three interactions with the curved walls before propagating outside the tube holders.

Abstract translation: 灭菌系统在无菌条件下密封第一管的第一端部和第二管的第二端部。 灭菌系统包括消毒室和电子枪，其在灭菌室中产生电子分布。 灭菌系统还包括主轴和保持器，其将连接器放置并旋转在电子分布中。 灭菌系统还包括第一和第二管保持器，每个管座具有可移动地联接到灭菌室的弯曲壁，以在相应的端部与连接器分离的第一位置和相应的端部与连接器相连的第二位置之间移动 。 每个弯曲的壁具有这样的形状，使得在消毒室内产生的x射线在传播到管保持器外部之前经历与弯曲壁的至少三个相互作用。

公开(公告)号：US4412835A

公开(公告)日：1983-11-01

申请号：US395796

申请日：1982-07-06

Applicant: Dudley W. C. Spencer

Inventor： Dudley W. C. Spencer

IPC: A61M39/14 ,  B29C65/20 ,  A61M5/00 ,  B32B31/00

CPC classification number: A61M39/146 ,  A61M39/143 ,  B29C65/2038 ,  B29C65/2046 ,  B29C65/2076 ,  B29C65/305 ,  B29C66/522 ,  B29C66/81431 ,  B29C66/83221 ,  B29C66/8324 ,  B29C66/857 ,  B29C66/81423 ,  Y10S604/905

Abstract: A process, apparatus and system for making a sterile connection between two thermoplastic resin tubes is disclosed. Side sections of the adjacently placed tubes are melted by passing a heated elongated body therethrough to form a molten seal between a surface of the heated body and the adjacent side sections, thereby providing a seal between the interior and exterior of said tubes. The resulting molten tube sections are urged together as they are slid off an end of the elongated body. As the thermoplastic resin cools a sterile weld is formed.

Abstract translation: 公开了一种用于在两个热塑性树脂管之间进行无菌连接的工艺，设备和系统。 相邻放置的管的侧部通过使加热的细长体通过其而熔化，以在加热体的表面和相邻的侧部之间形成熔融密封，从而在所述管的内部和外部之间提供密封。 所得到的熔融管段在细长体的端部滑动时被推动在一起。 当热塑性树脂冷却时，形成无菌焊缝。

公开(公告)号：US4325417A

公开(公告)日：1982-04-20

申请号：US27575

申请日：1979-04-06

Applicant: Daniel R. Boggs ,  Peter C. Kwong ,  Dean G. Laurin

Inventor： Daniel R. Boggs ,  Peter C. Kwong ,  Dean G. Laurin

IPC: A61L2/08 ,  A61M39/14 ,  B29C35/08 ,  B29C65/00 ,  B29C65/02 ,  B29C65/14 ,  B29C65/58 ,  F16L37/26 ,  F16L55/10 ,  B65B3/04

CPC classification number: B29C65/58 ,  A61L2/08 ,  A61M39/143 ,  B29C65/1435 ,  B29C65/148 ,  B29C65/7473 ,  B29C66/137 ,  B29C66/5221 ,  B29C66/5223 ,  B29C66/52298 ,  B29C66/534 ,  B29C66/54 ,  B29C66/73362 ,  B29C66/73776 ,  B29C66/73921 ,  B29C66/857 ,  F16L37/26 ,  F16L55/10 ,  A61M2039/1027 ,  B29C2035/0822 ,  B29C2793/0045 ,  B29C65/1406 ,  B29C65/1409 ,  B29C65/1412 ,  B29C65/16 ,  B29C66/71 ,  B29C66/73366 ,  B29K2023/00 ,  B29K2027/12 ,  B29K2067/006 ,  B29K2069/00 ,  B29K2077/00 ,  B29K2995/0025 ,  B29K2995/0027 ,  B29L2031/753 ,  Y10S604/905

Abstract: A connector member for a fluid flow path is provided which comprises a transparent housing enclosing an opaque barrier membrane or wall portion blocking flow through the flow path. The barrier membrane is adapted to be openable by exposure to radiant energy from the exterior through the transparent housing. In accordance with this invention, the barrier membrane is made of a predominantly crystalline plastic material, and, accordingly, exhibits a relatively sharp melting point for improved opening characteristics upon exposure to the radiant energy.

Abstract translation: 提供了一种用于流体流动路径的连接器构件，其包括封闭不透明阻挡膜的透明壳体或阻挡流过所述流动路径的壁的壁部分。 阻挡膜适于通过从外部通过透明壳体暴露于辐射能而可打开。 根据本发明，阻挡膜由主要为结晶的塑料材料制成，因此，在暴露于辐射能时，显示出相当尖的熔点以改善开口特性。

公开(公告)号：US20240024652A1

公开(公告)日：2024-01-25

申请号：US18479281

申请日：2023-10-02

Applicant: ICU Medical, Inc.

Inventor： Thomas F. Fangrow, JR. ,  George A. Lopez

IPC: A61M39/10 ,  A61M39/14 ,  A61M39/22 ,  A61M39/26

CPC classification number: A61M39/1011 ,  A61M39/10 ,  A61M39/14 ,  A61M39/22 ,  A61M39/26 ,  A61M2039/268 ,  A61M2039/1033 ,  A61M2039/1038 ,  A61M2039/1044 ,  A61M2039/1061 ,  A61M2039/261 ,  A61M39/143

Abstract: A luer connector including a rigid housing having a first end and a second end. The housing further including a rigid tubular male portion at the first end, a rigid tubular female portion at the second end, and a longitudinal opening therethrough. The male portion is configured to be engageable with a female connector. The female portion is configured to be engageable with a male connector and to prevent the disengagement of the male connector from the female portion. In some embodiments, the female portion is configured to maintain a fixed rotational position when the male connector is being threaded therewith, but to rotate with the male connector once the male connector has become fully engaged with the female portion so as to prevent the male connector from becoming unthreaded from the female portion.

公开(公告)号：US09550015B2

公开(公告)日：2017-01-24

申请号：US14634264

申请日：2015-02-27

Applicant: Biomet Biologics, LLC

Inventor： Alan Gray

IPC: A61M1/02 ,  A61J1/14 ,  B65B1/04 ,  A61M39/14

CPC classification number: A61M1/0209 ,  A61J1/1443 ,  A61M1/02 ,  A61M1/0218 ,  A61M1/0259 ,  A61M1/0272 ,  A61M1/0281 ,  A61M39/14 ,  A61M39/143 ,  A61M39/146 ,  A61M2202/0429 ,  A61M2205/60 ,  A61M2205/6009 ,  A61M2205/7518 ,  B65B1/04 ,  Y10S29/048 ,  Y10S200/42 ,  Y10S220/29 ,  Y10S604/905

Abstract: Delivering a blood processing solution to blood in a blood bag includes coupling a first tube to a vented spike at one end and to a Y-shaped tube connector at a second end. An in-line microbiotic barrier filter is coupled to the first tube between its ends. A second tube is coupled to a transfer bag at one end and to the Y-shaped tube connector at its other end. A third tube is coupled to the output of the Y-shaped tube connector and sealed at its distal end. The blood bag includes a fourth tube that is sealed at a distal end. The third tube is welded to the fourth tube using a sterile tubing welder, wherein a functionally-closed, sterile flow path through which the blood processing solution can flow into the blood bag is maintained.

Abstract translation: 向血液袋中的血液提供血液处理溶液包括将第一管连接到一端的通风尖端和在第二端处连接到Y形管连接器。 在线微生物屏障过滤器在其端部之间耦合到第一管。 第二管在一端连接到传送袋，并在其另一端连接到Y形管连接器。 第三管连接到Y形管连接器的输出端并在其远端密封。 血袋包括在远端密封的第四管。 使用无菌管焊机将第三管焊接到第四管，其中维持血液处理溶液可以通过其流入血袋的功能封闭的无菌流动路径。

公开(公告)号：US20140077488A1

公开(公告)日：2014-03-20

申请号：US14088781

申请日：2013-11-25

Applicant: Fenwal, Inc.

Inventor： Christopher Wegener ,  Kyungyoon Min ,  Mark Brierton ,  Benjamin Kusters ,  James Madsen ,  William H. Cork

IPC: A61M39/14 ,  B29C65/02

CPC classification number: A61M39/143 ,  A61M39/14 ,  B29C65/022 ,  B29C65/2015 ,  B29C65/203 ,  B29C65/30 ,  B29C65/32 ,  B29C65/3444 ,  B29C65/3456 ,  B29C65/36 ,  B29C65/3644 ,  B29C65/3656 ,  B29C65/4855 ,  B29C65/5021 ,  B29C65/5057 ,  B29C65/7841 ,  B29C66/0342 ,  B29C66/1142 ,  B29C66/3494 ,  B29C66/5221 ,  B29C66/5223 ,  B29C66/52298 ,  B29C66/5346 ,  B29C66/5414 ,  B29C66/543 ,  B29C66/71 ,  B29C66/72321 ,  B29C66/73115 ,  B29C66/73141 ,  B29C66/857 ,  B29C66/91231 ,  B29C66/91421 ,  B29C66/91651 ,  B29C66/919 ,  B29C66/91933 ,  B29C66/949 ,  B29C66/954 ,  B29K2027/06 ,  B29K2023/12 ,  B29K2067/003

Abstract: Fluid flow conduits and apparatus and methods for joining the conduits, preferably in a sterile manner, are disclosed. Each conduit has a polymeric open end that is sealed by a sealing member that may include a heating element. The polymeric end material is melted, the sealing members are moved to expose the melted open ends of the conduits and the ends are brought together to form a fused or welded connection between the conduits.

Abstract translation: 公开了流体流动管道以及用于连接管道的装置和方法，优选以无菌方式。 每个管道具有聚合物开口端，该开口端由可包括加热元件的密封构件密封。 聚合物端部材料被熔化，密封构件被移动以暴露导管的熔化的开口端，并且端部被带到一起以形成导管之间的熔接或焊接连接。

公开(公告)号：US20120041391A1

公开(公告)日：2012-02-16

申请号：US13210261

申请日：2011-08-15

Applicant: Thomas F. Fangrow ,  George A. Lopez

Inventor： Thomas F. Fangrow ,  George A. Lopez

IPC: A61M39/22 ,  A61M39/12

CPC classification number: A61M39/1011 ,  A61M39/10 ,  A61M39/14 ,  A61M39/143 ,  A61M39/22 ,  A61M39/26 ,  A61M2039/1033 ,  A61M2039/1038 ,  A61M2039/1044 ,  A61M2039/1061 ,  A61M2039/261 ,  A61M2039/268

Abstract: Some embodiments comprise a connector including a rigid housing having a first end and a second end. A second member can be positioned at a second end portion of the housing and be engageable with a second device. The second member can have a body portion having a first body portion, a second body portion, and a flow lumen extending axially through the body portion, an annular covering portion extending in a radial direction away from the body portion, a receiving portion extending away from the covering portion in an axial direction, and at least one protrusion extending radially away from an outside surface of the body portion. In some embodiments, the second member can be supported by the housing such that, in an assembled state, the first body portion is positioned within the housing and such that the annular covering portion and the second body portion are positioned outside the housing.

Abstract translation: 一些实施例包括具有第一端和第二端的刚性壳体的连接器。 第二构件可以定位在壳体的第二端部处并且可以与第二装置接合。 第二构件可以具有主体部分，主体部分，第二主体部分和沿着主体部分轴向延伸的流动腔体，沿径向延伸远离主体部分的环形覆盖部分，延伸远离的接收部分 从所述覆盖部分沿着轴向方向，以及至少一个突出部，其径向地远离所述主体部分的外表面延伸。 在一些实施例中，第二构件可以由壳体支撑，使得在组装状态下，第一主体部分定位在壳体内，并且使得环形覆盖部分和第二主体部分位于壳体外部。