Abstract:
Formation of a sterile connection includes inserting a first aseptic coupling device into a second aseptic coupling device, removing a first membrane from the first aseptic coupling device and a second membrane from the second aseptic coupling device, and rotating a locking clip on the first aseptic coupling device to compress a first seal member of the first aseptic coupling device with a second seal member of the second aseptic coupling device to form a sterile fluid passageway.
Abstract:
An adapter includes a substantially rigid body having a distal portion, a proximal portion, a central opening formed at least in part by an inner wall of the body, and a longitudinal axis extending substantially centrally through the opening. The distal portion includes an annular ring having a top surface and a ridge disposed opposite the top surface, the ridge extending substantially perpendicular to the longitudinal axis. The distal. The adapter also includes a seal configured to form a substantially fluid-tight seal with a surface of a fitting removably attachable to the adapter.
Abstract:
The invention relates to a connection system for releasably coupling a first body (5) with a flange (25) to a fluid-conducting system in a force-fitting manner, and the invention also relates to a connection system for releasably coupling the interior of a first fluid-conducting body (5) to the interior of a second fluid-conducting body (3) in a force-fitting manner. The second body (3) has a second end with a circumferential wall (22), a membrane contact portion (9) which can be found on the wall, and an opening (43). A retaining element (2) has a passage (35) and a peripheral outer edge (24). One side and/or the passage (35) of the retaining element (2) is coupled to the membrane (1), and an annular wall (26) is arranged on the same side, said annular wall being connected to the circumferential wall (22) of the second body (3). The other side is designed to contact the surface of the flange (25) of the first body (5). The retaining element (2) can also be integrated into the second body (3) when the first body (5) is fluid-conductive. The releasable connection element (4) is designed to at least partly surround the peripheral outer edge (24) of the retaining element (2) and the flange (25) of the first body (5).
Abstract:
Fluid transfer device and method that allows for sterile wet connections, allows the connection to be reversed, and allows the connection to be reconnected, while leaving the connectors sterile and reusable under pressure. In certain embodiments, the device includes a first member and a second member, the latter adapted to receive the former in locking engagement upon actuation of the device to create fluid communication between the two in a sterile manner. Each of the members include a door that when opened, allows the first member to be linearly displaced into the second member to allow fluid to be transferred. When fluid transfer is complete, the first member can be retracted from the second member, and the doors closed.
Abstract:
Disclosed herein is a fluid connection port for forming a working fluid connection between a deformable, flexible tube and a fluid handling device, the fluid connection port comprising a bore extending from an exterior surface of the fluid handling device to an internal fluid handling feature, the bore comprising a narrow diameter bore section adjacent the exterior surface of the fluid handling device, a larger diameter bore section adjacent the internal fluid handling feature, and a shoulder separating the narrow diameter bore section and the larger diameter bore section, wherein the diameter of the bore at the narrow diameter bore section is less than the outside diameter of the deformable, flexible tube.
Abstract:
Formation of a sterile connection includes inserting a first aseptic coupling device into a second aseptic coupling device, removing a first membrane from the first aseptic coupling device and a second membrane from the second aseptic coupling device, and rotating a locking clip on the first aseptic coupling device to compress a first seal member of the first aseptic coupling device with a second seal member of the second aseptic coupling device to form a sterile fluid passageway.
Abstract:
Luer connector including a primary Luer male connector, having a secondary female section extending from a top distal part of the primary Luer male connector back towards a proximal part thereof, the primary Luer male connector including a first inner fluid flow channel extending from a proximal end thereof to the secondary female section, the primary Luer male connector being configured to mate with a primary Luer female connector having a secondary male section including a second inner fluid flow channel.
Abstract:
A wear-heat-resistant anti-bacterial anti-fouling steel wire framed pipe and a manufacturing method thereof are provided. The steel wire framed pipe includes: an anti-bacterial anti-fouling inner layer, an enhancement layer and a wear-heat-resistant outer layer from inside to outside in turn, wherein: the anti-bacterial anti-fouling inner layer is made from antifouling and antibacterial composite modified polyethylene; the wear-heat-resistant outer layer is made from wear-resistant cross-linked modified PE-RT; the enhancement layer includes an interlayer and two steel wire gauze layers respectively coating on an inner surface and an outer surface of the interlayer, and the interlayer is respectively bonded with the anti-bacterial anti-fouling inner layer and the wear-heat-resistant outer layer via hot-melt adhesive. The steel wire framed pipe provided by the present invention has high structural strength, wear-resistance, heat-resistance, and anti-bacterial and anti-fouling properties.
Abstract:
Some fluid coupling devices described herein are configured for use in fluid systems for purposes of providing a single-use, aseptic disconnection functionality that substantially prevents fluid spillage when being disconnected.
Abstract:
Fluid-connection device for connecting a flexible pipe defining a first fluid space to a second flexible pipe or a flexible fluid enclosure in a biopharmaceutical assembly, includes a first connector and a second connector equivalent thereto, the first connector and second connector adapted to be coupled together in a genderless manner, by an insertion movement that is essentially an axial translation, into a relative coupling position, which defines a mating plane, each of the connectors including, in an alternating manner along the circumferential direction, N flexible snap-fitting tabs and N stop surfaces, the flexible snap-fitting tabs projecting axially forwards relative to the mating plane, and the stop surfaces being set back from the mating plane so that, in the coupling position, the snap-fitting tabs of one connector clip into place on the stop surfaces of the other connector, such that the resulting position is locked by the snap-fitting tabs.