知搜-全球专利检索

  1. 登录
  2. 注册

搜索结果

414 条记录 (耗时 0.031 秒)

    Apparatus and Method for Simultaneous Imaging and Execution of Contact-Free Directed Hydrodynamic Flow
    8.
    发明公开
    Apparatus and Method for Simultaneous Imaging and Execution of Contact-Free Directed Hydrodynamic Flow 审中-公开

    公开(公告)号：US20240142761A1

    公开(公告)日：2024-05-02

    申请号：US18497032

    申请日：2023-10-30

    申请人： Max-Planck-Gesellschaft zur Förderung der Wissenschaften E.V.

    发明人： Moritz Kreysing ,  Anatol Fritsch ,  Matthaeus Mittasch

    IPC分类号： G02B21/36 ,  B01L3/00 ,  G02B21/00 ,  G02B21/02 ,  G02B21/08 ,  G02B21/28 ,  G02B21/30

    CPC分类号： G02B21/36 ,  B01L3/50273 ,  G02B21/0032 ,  G02B21/02 ,  G02B21/08 ,  G02B21/28 ,  G02B21/30 ,  B01L2400/0463 ,  G01N21/6458

    摘要： The present invention relates to an apparatus for simultaneous imaging and execution of contact-free directed hydrodynamic flow in a specimen with at least one light source, in particular a laser, adapted to dynamically heat the interior and/or a surface of the specimen, a microscope with an objective adapted to image at least a part of the specimen and to guide, in particular focus, a light beam of the light source, in particular a laser beam, into and/or onto the specimen to heat at least one specified location of the specimen, means for manipulating the specified location, and a sample chamber for the specimen that is accessible for imaging radiation and the light beam to allow simultaneous imaging and manipulation of the sample via the objective. Furthermore the present invention is directed to a method for simultaneous imaging and executing contact-free directed hydrodynamic flow in a specimen wherein, at least one light source, in particular a laser, dynamically heats the interior and/or a surface of the specimen via a light beam, in particular via a laser beam, the beam of the at least one light source is directed to the specimen through an objective of a microscope, the light beam is variably guided, in particular focused, to specified locations of the specimen inducing a hydrodynamic flow in the specimen, and imaging the specimen via the same objective as used for introduction of the light beam.

    AUTONOMOUS DATA LOGGER
    9.
    发明公开
    AUTONOMOUS DATA LOGGER 审中-公开

    公开(公告)号：US20240094033A1

    公开(公告)日：2024-03-21

    申请号：US18263031

    申请日：2022-01-25

    申请人： Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V.

    发明人： Timm WILD ,  Martin WIKELSKI

    IPC分类号： G01D9/00

    CPC分类号： G01D9/005

    摘要： The present invention relates to a device for recording and storing of measurement data related to an object or living subject. The device comprises at least one sensor configured to measure data related to the object or living subject, a memory, and a controller configured to store the measured data in the memory. At least one photosensitive element is configured to convert electromagnetic radiation into electrical current. A transceiver is configured to transmit the measured and/or stored data and to receive data signals. At least one capacitor is configured to store electrical current from the at least one photosensitive element. The controller is configured to measure the voltage of the at least one capacitor. The controller is further configured to forecast an output voltage of the at least one capacitor based on measured voltages, and the controller is configured to increase or decrease the rate of sampling and storing of the measured data in the memory and/or to increase or decrease the rate of transmitting the measured and/or stored data depending on the measured voltage or the forecasted voltage.

    PEPTIDE PURIFICATION USING MIXED-PHASE SOLID PHASE EXTRACTION MATERIAL
    10.
    发明公开
    PEPTIDE PURIFICATION USING MIXED-PHASE SOLID PHASE EXTRACTION MATERIAL 审中-公开

    公开(公告)号：US20240092826A1

    公开(公告)日：2024-03-21

    申请号：US18361539

    申请日：2023-07-28

    申请人： MAX-PLANCK-GESELLSCHAFT ZUR FÖRDERUNG DER WISSENSCHAFTEN E.V.

    发明人： Nils A. KULAK ,  Garwin PICHLER ,  Matthias MANN

    IPC分类号： C07K1/16

    CPC分类号： C07K1/165 ,  G01N33/5002

    摘要： The present invention relates to a method of purifying peptides and/or polypeptides, said method comprising or consisting of: (a) loading a sample comprising peptides and/or polypeptides under acidic or neutral aqueous conditions on mixed-phase solid phase extraction (SPE) material, wherein said material consists of or comprises reversed phase/ion exchange material; (b) washing said mixed-phase SPE material with (ba) an acidic or neutral composition comprising at least 50% (v/v) organic solvent; and/or (bb) an acidic or neutral aqueous solution; and (c) eluting said peptides and/or polypeptides from said mixed-phase SPE material with an alkaline composition comprising at least 50% (v/v) organic solvent.