公开(公告)号：US20140080131A1

公开(公告)日：2014-03-20

申请号：US13789405

申请日：2013-03-07

Applicant: SAMSUNG ELECTRONICS CO., LTD.

Inventor： Ye-ryoung YONG ,  Hyun-ju KANG

IPC: G01N1/34

CPC classification number: G01N1/34 ,  G01N33/92

Abstract: The invention provides compositions, kits, and methods for analyzing vesicles or vesicle proteins, glycoproteins, lipids or nucleic acids, and may be used for screening ligands that have a binding affinity to vesicles.

Abstract translation: 本发明提供用于分析囊泡或囊泡蛋白，糖蛋白，脂质或核酸的组合物，试剂盒和方法，并且可用于筛选对囊泡具有结合亲和力的配体。

公开(公告)号：US20140093880A1

公开(公告)日：2014-04-03

申请号：US13857087

申请日：2013-04-04

Applicant: SAMSUNG ELECTRONICS CO., LTD.

Inventor： Ga-hee KIM ,  Chang-eun YOO ,  Ye-ryoung YONG ,  Myo-yong LEE

IPC: G01N1/40 ,  C12Q1/68 ,  G01N33/574

CPC classification number: G01N1/405 ,  C12Q1/6886 ,  G01N33/5076 ,  G01N33/57492

Abstract: A composition, a kit, and a method of isolating a vesicle from a sample using a compound comprising zwitterion moieties, which may be used to analyze vesicles, and proteins, glycoprotein, lipids, or nucleic acids thereof.

Abstract translation: 使用可用于分析囊泡的包含两性离子部分的化合物和蛋白质，糖蛋白，脂质或其核酸的组合物，试剂盒和从样品中分离囊泡的方法。

公开(公告)号：US20150104879A1

公开(公告)日：2015-04-16

申请号：US14322570

申请日：2014-07-02

Applicant: Samsung Electronics Co., Ltd.

Inventor： Ye-ryoung YONG ,  Hyun-ju Kang ,  Ga-hee Kim ,  Kyung-hee Park ,  Jong-myeon Park

IPC: G01N33/574 ,  C07K16/30

CPC classification number: C07K16/303 ,  C07K16/2896

Abstract: Provided is method of diagnosing liver cancer in a subject, the method comprising contacting a sample from a subject with a substance that specifically binds to transmembrane emp24 domain trafficking protein 2 (TMED2), cluster of differentiation 43 (CD43), or any combination thereof on the surface of a microvesicle; and measuring the level of the substance bound to microvesicles in the sample; and related methods and compositions.

Abstract translation: 提供了一种在受试者中诊断肝癌的方法，所述方法包括使来自受试者的样品与特异性结合跨膜emp24结构域运输蛋白2（TMED2），分化簇43（CD43）或其任何组合的物质接触 微泡的表面; 并测量与样品中微泡结合的物质的含量; 以及相关方法和组成。

公开(公告)号：US20140099652A1

公开(公告)日：2014-04-10

申请号：US13785945

申请日：2013-03-05

Applicant: SAMSUNG ELECTRONICS CO., LTD.

Inventor： Hyun-ju KANG ,  Ye-ryoung YONG ,  Myo-yong LEE

IPC: G01N21/64

CPC classification number: G01N21/6486 ,  G01N21/64 ,  G01N21/6428 ,  G01N33/582

Abstract: Provided is a method of monitoring a vesicle in a sample, including contacting a vesicle in a sample with a membrane permeable marker that is converted into a detectable marker in the vesicle, measuring a signal of the detectable marker, and monitoring the vesicle based on the measured signal.

Abstract translation: 提供了一种监测样品中的囊泡的方法，包括使样品中的囊泡与膜可渗透标记物接触，所述膜可渗透标记物在小泡中转化为可检测标记物，测量可检测标记物的信号，并基于 测量信号。

公开(公告)号：US20140080136A1

公开(公告)日：2014-03-20

申请号：US13857089

申请日：2013-04-04

Applicant: Samsung Electronics Co., Ltd.

Inventor： Hyun-ju KANG ,  Ye-ryoung YONG ,  Myo-yong LEE

IPC: G01N21/64

CPC classification number: G01N21/6486 ,  G01N33/582

Abstract: Provided are compositions, kits, and methods for detecting a vesicle comprising a membrane permeable marker that is converted into a detectable marker inside the vesicle.

Abstract translation: 提供了用于检测囊泡的组合物，试剂盒和方法，其包含膜可渗透标记，其在囊泡内转化为可检测标记。

公开(公告)号：US20130171697A1

公开(公告)日：2013-07-04

申请号：US13662333

申请日：2012-10-26

Applicant: Samsung Electronics Co., Ltd.

Inventor： Jong-myeon PARK ,  Myoung-soon KIM ,  Ye-ryoung YONG

IPC: C12P19/34 ,  C07H21/00 ,  B01L3/00

CPC classification number: B01L3/502753 ,  B01L3/502738 ,  B01L7/52 ,  B01L2300/0806 ,  B01L2300/0864 ,  B01L2300/1811 ,  B01L2300/1827 ,  B01L2300/1861 ,  B01L2300/1872 ,  B01L2400/0677 ,  C12N1/08

Abstract: A microfluidic device for controlling a flow of a fluid using centrifugal and rotational force based on a rotatable disc-type body, a method of separating a target material or performing emulsion nucleic acid amplification using the microfluidic device.

Abstract translation: 一种用于使用基于可旋转盘型体的离心和旋转力来控制流体流动的微流体装置，使用所述微流体装置分离靶材料或进行乳液核酸扩增的方法。