Abstract:
The invention provides compositions, kits, and methods for analyzing vesicles or vesicle proteins, glycoproteins, lipids or nucleic acids, and may be used for screening ligands that have a binding affinity to vesicles.
Abstract:
A method of detecting and recovering of exosomes in a sample, as well as a method of determining the recovery rate of exosomal recovery, and a method of screening for a material that induces secretion of the exosomes in a sample, which methods employ the use of a protease.
Abstract:
Provided is a method of monitoring a vesicle in a sample, including contacting a vesicle in a sample with a membrane permeable marker that is converted into a detectable marker in the vesicle, measuring a signal of the detectable marker, and monitoring the vesicle based on the measured signal.
Abstract:
Provided are compositions, kits, and methods for detecting a vesicle comprising a membrane permeable marker that is converted into a detectable marker inside the vesicle.