公开(公告)号：US20140099652A1

公开(公告)日：2014-04-10

申请号：US13785945

申请日：2013-03-05

Applicant: SAMSUNG ELECTRONICS CO., LTD.

Inventor： Hyun-ju KANG ,  Ye-ryoung YONG ,  Myo-yong LEE

IPC: G01N21/64

CPC classification number: G01N21/6486 ,  G01N21/64 ,  G01N21/6428 ,  G01N33/582

Abstract: Provided is a method of monitoring a vesicle in a sample, including contacting a vesicle in a sample with a membrane permeable marker that is converted into a detectable marker in the vesicle, measuring a signal of the detectable marker, and monitoring the vesicle based on the measured signal.

Abstract translation: 提供了一种监测样品中的囊泡的方法，包括使样品中的囊泡与膜可渗透标记物接触，所述膜可渗透标记物在小泡中转化为可检测标记物，测量可检测标记物的信号，并基于 测量信号。

公开(公告)号：US20140080136A1

公开(公告)日：2014-03-20

申请号：US13857089

申请日：2013-04-04

Applicant: Samsung Electronics Co., Ltd.

Inventor： Hyun-ju KANG ,  Ye-ryoung YONG ,  Myo-yong LEE

IPC: G01N21/64

CPC classification number: G01N21/6486 ,  G01N33/582

Abstract: Provided are compositions, kits, and methods for detecting a vesicle comprising a membrane permeable marker that is converted into a detectable marker inside the vesicle.

Abstract translation: 提供了用于检测囊泡的组合物，试剂盒和方法，其包含膜可渗透标记，其在囊泡内转化为可检测标记。

公开(公告)号：US20140141418A1

公开(公告)日：2014-05-22

申请号：US13899223

申请日：2013-05-21

Applicant: SAMSUNG ELECTRONICS CO., LTD.

Inventor： Dong-hyun PARK ,  Sung-woo HONG ,  Kyung-hee PARK ,  Myo-yong LEE

IPC: C12Q1/68

CPC classification number: C12Q1/6876 ,  C12Q1/6844 ,  C12Q2525/207 ,  C12Q2525/307 ,  C12Q2531/119

Abstract: Provided is a dual-hybridization polynucleotide including a first complementary region that is complementary to the 3′-terminus of a target nucleic and a second complementary region that is complementary to the 5′-terminus of the target nucleic acid, a composition and kit including the polynucleotide, and a method of producing a nucleotide sequence complementary to the target nucleic acid. The first complementary region to be bound at the 3′-terminus of the target nucleic acid can be shortened and the target nucleic acid may be amplified with excellent specificity and/or sensitivity.

Abstract translation: 提供了双杂交多核苷酸，其包含与靶核酸的3'末端互补的第一互补区和与靶核酸的5'末端互补的第2互补区，包含 多核苷酸，以及产生与靶核酸互补的核苷酸序列的方法。 可以缩短在靶核酸的3'-末端结合的第一个互补区，并且以优异的特异性和/或灵敏度扩增靶核酸。

公开(公告)号：US20130157300A1

公开(公告)日：2013-06-20

申请号：US13678357

申请日：2012-11-15

Applicant: SAMSUNG ELECTRONICS CO., LTD.

Inventor： Dong-hyun PARK ,  Hyun-ju KANG ,  Myo-yong LEE

IPC: G01N21/64

CPC classification number: G01N21/6486 ,  C12Q1/34 ,  C12Q1/37 ,  G01N21/6428 ,  G01N2500/10

Abstract: A method of detecting and recovering of exosomes in a sample, as well as a method of determining the recovery rate of exosomal recovery, and a method of screening for a material that induces secretion of the exosomes in a sample, which methods employ the use of a protease.

Abstract translation: 一种检测和回收样品中外来体的方法，以及确定外来物质回收率回收率的方法，以及筛选诱导样品中外来体分泌物质的方法，该方法采用 一种蛋白酶。

公开(公告)号：US20140093880A1

公开(公告)日：2014-04-03

申请号：US13857087

申请日：2013-04-04

Applicant: SAMSUNG ELECTRONICS CO., LTD.

Inventor： Ga-hee KIM ,  Chang-eun YOO ,  Ye-ryoung YONG ,  Myo-yong LEE

IPC: G01N1/40 ,  C12Q1/68 ,  G01N33/574

CPC classification number: G01N1/405 ,  C12Q1/6886 ,  G01N33/5076 ,  G01N33/57492

Abstract: A composition, a kit, and a method of isolating a vesicle from a sample using a compound comprising zwitterion moieties, which may be used to analyze vesicles, and proteins, glycoprotein, lipids, or nucleic acids thereof.

Abstract translation: 使用可用于分析囊泡的包含两性离子部分的化合物和蛋白质，糖蛋白，脂质或其核酸的组合物，试剂盒和从样品中分离囊泡的方法。