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    Integrated bound-mode spectral/angular sensors
    1.
    发明授权
    Integrated bound-mode spectral/angular sensors 有权

    公开(公告)号：US10408673B2

    公开(公告)日：2019-09-10

    申请号：US15706440

    申请日：2017-09-15

    Applicant: STC.UNM

    Inventor： Steven R. J. Brueck ,  Alexander Neumann ,  Payman Zarkesh-Ha

    IPC: G01J5/02 ,  G01J1/06 ,  G01J3/02 ,  G01J1/44 ,  G01J3/18 ,  G01J3/28 ,  G02B6/122 ,  G02B6/124 ,  H01L27/144 ,  H01L31/02 ,  H01L31/0216 ,  H01L31/0232 ,  H01L31/103 ,  G02B6/12

    Abstract: A 2-D sensor array includes a semiconductor substrate and a plurality of pixels disposed on the semiconductor substrate. Each pixel includes a coupling region and a junction region, and a slab waveguide structure disposed on the semiconductor substrate and extending from the coupling region to the region. The slab waveguide includes a confinement layer disposed between a first cladding layer and a second cladding layer. The first cladding and the second cladding each have a refractive index that is lower than a refractive index of the confinement layer. Each pixel also includes a coupling structure disposed in the coupling region and within the slab waveguide. The coupling structure includes two materials having different indices of refraction arranged as a grating defined by a grating period. The junction region comprises a p-n junction in communication with electrical contacts for biasing and collection of carriers resulting from absorption of incident radiation.

    Innovative nanopore sequencing technology
    2.
    发明授权
    Innovative nanopore sequencing technology 有权

    公开(公告)号：US10184930B2

    公开(公告)日：2019-01-22

    申请号：US15039825

    申请日：2014-11-26

    Applicant: STC.UNM

    Inventor： Steven R. J. Brueck ,  Jeremy Scott Edwards ,  Alexander Neumann ,  Yuliya Kuznetsova ,  Edgar A. Mendoza

    IPC: G01N21/00 ,  G01N33/487 ,  C12Q1/6869 ,  B01L3/00 ,  C23C16/34 ,  C23C16/455 ,  C23C16/50 ,  G01N21/65

    Abstract: Methods and apparatus for long read, label-free, optical nanopore long chain molecule sequencing. In general, the present disclosure describes a novel sequencing technology based on the integration of nanochannels to deliver single long-chain molecules with widely spaced (>wavelength), ˜1-nm aperture “tortuous” nanopores that slow translocation sufficiently to provide massively parallel, single base resolution using optical techniques. A novel, directed self-assembly nanofabrication scheme using simple colloidal nanoparticles is used to form the nanopore arrays atop nanochannels that unfold the long chain molecules. At the surface of the nanoparticle array, strongly localized electromagnetic fields in engineered plasmonic/polaritonic structures allow for single base resolution using optical techniques.

    Innovative Nanopore Sequencing Technology
    6.
    发明申请
    Innovative Nanopore Sequencing Technology 审中-公开

    公开(公告)号：US20190227050A1

    公开(公告)日：2019-07-25

    申请号：US16215139

    申请日：2018-12-10

    Applicant: STC.UNM

    Inventor： Steven R.J. Brueck ,  Jeremy Scott Edwards ,  Alexander Neumann ,  Yuliya Kuznetsova ,  Edgar A. Mendoza

    IPC: G01N33/487 ,  C23C16/50 ,  C23C16/455 ,  C23C16/34 ,  B01L3/00 ,  C12Q1/6869 ,  G01N21/65

    Abstract: Methods and apparatus for long read, label-free, optical nanopore long chain molecule sequencing. In general, the present disclosure describes a novel sequencing technology based on the integration of nanochannels to deliver single long-chain molecules with widely spaced (>wavelength), ˜1-nm aperture “tortuous” nanopores that slow translocation sufficiently to provide massively parallel, single base resolution using optical techniques. A novel, directed self-assembly nanofabrication scheme using simple colloidal nanoparticles is used to form the nanopore arrays atop nanochannels that unfold the long chain molecules. At the surface of the nanoparticle array, strongly localized electromagnetic fields in engineered plasmonic/polaritonic structures allow for single base resolution using optical techniques.

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