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23 条记录 (耗时 0.021 秒)

    Recovery of pure 2-methyl-2-hydroxy-heptanone-6
    1.
    发明授权
    Recovery of pure 2-methyl-2-hydroxy-heptanone-6 失效
    纯2-甲基-2-羟基 - 庚酮-6的回收

    公开(公告)号：US3957730A

    公开(公告)日：1976-05-18

    申请号：US506290

    申请日：1974-09-16

    申请人： Roman Fischer ,  Hermann Overwien ,  Axel Nissen

    发明人： Roman Fischer ,  Hermann Overwien ,  Axel Nissen

    IPC分类号： C07C20060101 ,  C07C49/17 ,  C07D309/04 ,  C07C45/24

    CPC分类号： C07C45/85

    摘要： A process for the recovery of pure 2-methyl-2-hydroxyheptanone-6 by conversion of impure 2-methyl-2-hydroxyheptanone-6 into 2,2,6-trimethyl 2,3-hydro-4-H-pyran by treatment with an acid which is not volatile under the reaction conditions at a temperature of from 30.degree. to 150.degree.C, purification of the 2,2,6-trimethyl-2,3-hydro-4-H-pyran thus obtained by distillation, reaction of the purified 2,2,6-trimethyl-2,3-hydro-4-H-pyran with water in the presence of an acid ion exchanger and removal of the excess water from the aqueous solution of 2-methyl-2-hydroxyheptanone-6 thus obtained by distillation. 2-methyl-2-hydroxyheptanone-6 is suitable for the production of 2-methyl-2-hydroxy-6-aminoheptane which is effective as a pharmaceutical for conditions of the heart and circulation.

    Preparation of citral
    2.
    发明授权
    Preparation of citral 失效
    柠檬醛的制备

    公开(公告)号：US4288636A

    公开(公告)日：1981-09-08

    申请号：US158346

    申请日：1980-06-10

    申请人： Axel Nissen ,  Walter Rebafka ,  Werner Aquila

    发明人： Axel Nissen ,  Walter Rebafka ,  Werner Aquila

    IPC分类号： C07C45/00 ,  C07C45/51 ,  C07C47/21 ,  C07C67/00

    CPC分类号： C07C45/515

    摘要： Citral (I) ##STR1## is prepared by heating an acetal (IIa) or (IIb) ##STR2## in the presence of an acid catalyst while continuously distilling from the reaction mixture the 3-methylbut-2-en-1-ol (III, prenol) eliminated during the reaction.

    摘要翻译： 柠檬酸（I）通过在酸催化剂的存在下加热缩醛（IIa）或（IIb）IIa IIa IIB而制备，同时从反应混合物中连续蒸馏3-甲基丁-2-醇， 烯丙醇（III，前醇）在反应期间消除。

    Manufacture of 2-methyl-2-hepten-6-one
    3.
    发明授权
    Manufacture of 2-methyl-2-hepten-6-one 失效
    制备2-甲基-2-庚烯-6-酮

    公开(公告)号：US4173588A

    公开(公告)日：1979-11-06

    申请号：US848211

    申请日：1977-11-03

    申请人： Heinrich Pasedach ,  Rudolf Mohr ,  Axel Nissen

    发明人： Heinrich Pasedach ,  Rudolf Mohr ,  Axel Nissen

    IPC分类号： C07C45/00 ,  B01J31/00 ,  C07B61/00 ,  C07C45/67 ,  C07C49/203 ,  C07C67/00 ,  C07C45/18

    CPC分类号： C07C45/676

    摘要： An improved process for the manufacture of 2-methyl-2-hepten-6-one by reacting an alkyl acetoacetate with 2-methyl-3-buten-2-ol in the presence of an organic aluminum compound such as aluminum trialcoholate, aluminum triacetoacetate, aluminum alkylacetoacetate or aluminum triaryloxylate. 2-Methyl-2-hepten-6-one is an intermediate for the manufacture of vitamins.

    摘要翻译： 通过使乙酰乙酸烷基酯与2-甲基-3-丁烯-2-醇在有机铝化合物如仲醇酸铝，三乙酰乙酸铝的存在下反应来制备2-甲基-2-庚烯-6-酮的改进方法 ，烷基乙酰乙酸铝或三芳氧基铝。 2-甲基-2-庚烯-6-酮是制造维生素的中间体。

    Manufacture of acetals
    5.
    发明授权
    Manufacture of acetals 失效
    缩醛的制造

    公开(公告)号：US4133836A

    公开(公告)日：1979-01-09

    申请号：US801561

    申请日：1977-05-31

    申请人： Axel Nissen ,  Gerd Kaibel

    发明人： Axel Nissen ,  Gerd Kaibel

    IPC分类号： C07C41/50 ,  B01J27/00 ,  C07C41/00 ,  C07C41/54 ,  C07C43/30 ,  C07C43/303 ,  C07C67/00 ,  C07C69/12 ,  C07C69/73

    摘要： A process for the manufacture of acetals by reacting aliphatic aldehydes with aliphatic alcohols, especially olefinically unsaturated aldehydes and allyl alcohols, in the presence of a distillable acid, especially nitric acid, using a rectifying column as the reaction vessel. The products may be used as starting materials for plastics, active substances, scents and vitamins.

    摘要翻译： 通过使用精馏塔作为反应容器，在可馏出的酸，特别是硝酸的存在下，使脂族醛与脂族醇，特别是烯属不饱和醛和烯丙醇反应来制造缩醛的方法。 该产品可用作塑料，活性物质，气味和维生素的起始原料。

    Preparation of chromane derivatives
    7.
    发明授权
    Preparation of chromane derivatives 失效
    色烯衍生物的制备

    公开(公告)号：US4268446A

    公开(公告)日：1981-05-19

    申请号：US121170

    申请日：1980-02-13

    申请人： Michael Horner ,  Axel Nissen

    发明人： Michael Horner ,  Axel Nissen

    IPC分类号： C07D311/72 ,  C07D311/66 ,  C07D311/58

    CPC分类号： C07D311/66

    摘要： Chromane derivatives (I) ##STR1## where R.sup.1, R.sup.2 and R.sup.3 are H or C.sub.1 -C.sub.8 -alkyl, R.sup.4 is H, C.sub.1 -C.sub.8 -alkyl or C.sub.1 -C.sub.8 -acyl and R.sup.5 is C.sub.1 -C.sub.8 -alkyl are prepared by reacting a hydroquinone (II) ##STR2## with a Lewis acid or a Lewis acid derivative having the same action, and with a nitrile CH.sub.2 .dbd.CH--C(R.sup.5)(OR.sup.6)CN (III), where R.sup.6 is H, C.sub.1 -C.sub.4 -acyl or C.sub.1 -C.sub.4 -alkyl, or with a compound from which III is formed in situ, in the presence of an inert solvent.

    摘要翻译： 色原烷衍生物（I）其中R 1，R 2和R 3是H或C 1 -C 8 - 烷基，R 4是H，C 1 -C 8 - 烷基或C 1 -C 8酰基，R 5是C 1 -C 8 - 烷基是通过 使氢醌（II）II与具有相同作用的路易斯酸或路易斯酸衍生物反应，并与腈CH2 = CH-C（R5）（OR6）CN（III）反应，其中R6为H，C1 -C 1-4酰基或C 1 -C 4 - 烷基，或与惰性溶剂存在下原位形成III的化合物反应。