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19 条记录 (耗时 0.018 秒)

    Recovery of pure 2-methyl-2-hydroxy-heptanone-6
    1.
    发明授权
    Recovery of pure 2-methyl-2-hydroxy-heptanone-6 失效
    纯2-甲基-2-羟基 - 庚酮-6的回收

    公开(公告)号：US3957730A

    公开(公告)日：1976-05-18

    申请号：US506290

    申请日：1974-09-16

    申请人： Roman Fischer ,  Hermann Overwien ,  Axel Nissen

    发明人： Roman Fischer ,  Hermann Overwien ,  Axel Nissen

    IPC分类号： C07C20060101 ,  C07C49/17 ,  C07D309/04 ,  C07C45/24

    CPC分类号： C07C45/85

    摘要： A process for the recovery of pure 2-methyl-2-hydroxyheptanone-6 by conversion of impure 2-methyl-2-hydroxyheptanone-6 into 2,2,6-trimethyl 2,3-hydro-4-H-pyran by treatment with an acid which is not volatile under the reaction conditions at a temperature of from 30.degree. to 150.degree.C, purification of the 2,2,6-trimethyl-2,3-hydro-4-H-pyran thus obtained by distillation, reaction of the purified 2,2,6-trimethyl-2,3-hydro-4-H-pyran with water in the presence of an acid ion exchanger and removal of the excess water from the aqueous solution of 2-methyl-2-hydroxyheptanone-6 thus obtained by distillation. 2-methyl-2-hydroxyheptanone-6 is suitable for the production of 2-methyl-2-hydroxy-6-aminoheptane which is effective as a pharmaceutical for conditions of the heart and circulation.

    Preparation of N-substituted cyclic amines
    3.
    发明授权
    Preparation of N-substituted cyclic amines 失效
    N-取代的环胺的制备

    公开(公告)号：US4910304A

    公开(公告)日：1990-03-20

    申请号：US331942

    申请日：1989-03-31

    申请人： Roman Fischer ,  Herbert Mueller ,  Dieter Voges

    发明人： Roman Fischer ,  Herbert Mueller ,  Dieter Voges

    IPC分类号： B01J23/78 ,  C07D295/023

    CPC分类号： B01J23/78 ,  C07D295/023 ,  Y02P20/582

    摘要： N-substituted cyclic amines of the general formula I ##STR1## where A is an alkylene group or a --(CH.sub.2).sub.n --[--O--(CH.sub.2).sub.m ].sub.r group which may be monosubstituted or polysubstituted by radicals R without the radicals R in a defined compound having to be identical, R is alkyl, alkoxyalkyl, unsubstituted or alkyl-substituted or alkoxy-substituted cycloalkyl, cycloalkylalkyl, aryl or arylalkyl, n and m independently of one another are each from 2 to 8 and r is from 1 to 3, the --(CH.sub.2).sub.n --[O--(CH.sub.2).sub.m ].sub.r group consisting of from 5 to 12 members, are prepared by reacting a primary amine of the general formula IIR--NH.sub.2 (II)with a diol of the general formula IIIHO--A--OH (III)where R and A have the abovementioned meanings, and hydrogen in the presence of a copper-containing hydrogenation/dehydrogenation catalyst at elevated temperatures and under superatmospheric pressure, by a process in which the reaction is carried out in the presence of a catalytic amount of a basic alkali metal compound or alkaline earth metal compound.

    摘要翻译： 其中A是亚烷基或 - （CH 2）n - [ - O-（CH 2）m] r基团，其可以被未经取代的基团R单取代或多取代， 定义化合物中的基团R必须相同，R是烷基，烷氧基烷基，未取代的或烷基取代的或烷氧基取代的环烷基，环烷基烷基，芳基或芳基烷基，n和m彼此独立地为2-8，r为 通过使通式II R-NH 2（II）的伯胺与式（Ⅳ）所示的式（Ⅳ）化合物与 其中R和A具有上述含义的通式III HO-A-OH（III）的二醇和在含铜氢化/脱氢催化剂存在下在升高的温度和超大气压下的氢，通过其中 反应在催化量的碱金属碱金属化合物或碱性碱存在下进行 h金属化合物。

    Production of high molecular weight .alpha.,.beta.-unsaturated aldehydes
    4.
    发明授权
    Production of high molecular weight .alpha.,.beta.-unsaturated aldehydes 失效
    生产高分子量{60，{62-不饱和醛

    公开(公告)号：US4021411A

    公开(公告)日：1977-05-03

    申请号：US583637

    申请日：1975-06-04

    申请人： Norbert Goetz ,  Roman Fischer

    发明人： Norbert Goetz ,  Roman Fischer

    IPC分类号： C07C45/70 ,  C07C45/71 ,  C07C47/20

    CPC分类号： C07C45/71 ,  C07C45/70

    摘要： A process for the production of high molecular weight .alpha.,.beta.-unsaturated aldehydes by alkylation of the .gamma.-carbon atom of a lower molecular weight .alpha.,.beta.-unsaturated aldehyde with a substituted allyl alcohol which has a chain branching in the 4-position carbon atom or a phenyl radical in the 4-position or of a corresponding allyl alcohol carboxylic ester at elevated temperature in the liquid phase.The products are valuable intermediates for the production of natural substances and odorants.

    摘要翻译： 通过用较低分子量的α，β-不饱和醛的γ-碳原子烷基化制备高分子量α，β-不饱和醛的方法，该取代的烯丙醇在4-位碳上具有支链分支 原子或4-位的苯基或相应的烯丙基醇羧酸酯在液相中升高的温度。

    Production of high molecular weight .alpha.,.beta.-unsaturated aldehydes
    6.
    发明授权
    Production of high molecular weight .alpha.,.beta.-unsaturated aldehydes 失效
    生产高分子量{60，{62-不饱和醛

    公开(公告)号：US4058536A

    公开(公告)日：1977-11-15

    申请号：US662346

    申请日：1976-03-01

    申请人： Norbert Goetz ,  Roman Fischer

    发明人： Norbert Goetz ,  Roman Fischer

    IPC分类号： C07C45/70 ,  C07C45/71 ,  C07C47/20 ,  C07D319/04

    CPC分类号： C07C45/71 ,  C07C403/14 ,  C07C45/70 ,  C07C2101/16

    摘要： A process for the production of high molecular weight .alpha.,.beta.-unsaturated aldehydes by alkylation of the .gamma.-carbon atom of a lower molecular weight .alpha.,.beta.-unsaturated aldehyde with a substituted allyl alcohol which has a chain branching in the 3-position carbon atom or a phenyl radical in the 3-position or of a corresponding allyl alcohol carboxylic ester at elevated temperature in the liquid phase.The products are valuable intermediates for the production of natural substances and odorants.

    摘要翻译： 通过用较低分子量的α，β-不饱和醛的γ-碳原子烷基化制备高分子量α，β-不饱和醛的方法，该取代的烯丙醇在3-位碳上具有支链分支 原子或3-位上的苯基或相应的烯丙醇羧酸酯在液相中升高的温度下进行。