公开(公告)号：US11348350B2

公开(公告)日：2022-05-31

申请号：US16785714

申请日：2020-02-10

Applicant: OLYMPUS CORPORATION

Inventor： Shinichi Takimoto ,  Yohei Tanikawa ,  Taiji Mine ,  Takayuki Nakatomi ,  Masakazu Fujii

IPC: G06V20/69 ,  G06F16/78 ,  G06V10/25

Abstract: An observation system includes a processor. The processor manages a plurality of images acquired in time series with respect to a biological sample which is being cultured, records a first comment and a first region of interest (RoI) in a storage device in association with the images based on user's instructions, and records a second comment and a second ROI in the storage device in association with the first comment based on user's instructions.

公开(公告)号：US11793391B2

公开(公告)日：2023-10-24

申请号：US17178815

申请日：2021-02-18

Applicant: OLYMPUS CORPORATION

Inventor： Ryosuke Ito ,  Yuki Shono ,  Takayuki Tsukagoshi ,  Yohei Tanikawa

IPC: A61B1/00 ,  G06T7/90 ,  A61B1/06 ,  A61B5/00 ,  G06T7/00 ,  H04N1/60 ,  A61B1/04

CPC classification number: A61B1/00057 ,  A61B1/044 ,  A61B1/0638 ,  A61B5/489 ,  G06T7/0014 ,  G06T7/90 ,  H04N1/6016 ,  G06T2207/10024 ,  G06T2207/10068 ,  G06T2207/30101

Abstract: An image processing device includes: one or more processors including hardware. The one or more processors are configured to: calculate, on a basis of a reference image acquired by capturing an image of a reference subject which has an optical characteristic that is equivalent to at least a part of a living body, image transformation parameters through congruence transformation that transforms a coordinate corresponding to a color of target region included in the reference image defined in a color space into a coordinate corresponding to an achromatic color in the color space; and perform, in the color space on a basis of the calculated image transformation parameters, the congruence transformation of colors of a color image acquired by capturing an image of the living body, the color image being constituted by at least two monochromatic image corresponding to different illumination having different center wavelengths.

公开(公告)号：US10136802B2

公开(公告)日：2018-11-27

申请号：US14828873

申请日：2015-08-18

Applicant: OLYMPUS CORPORATION

Inventor： Yohei Tanikawa ,  Yasunobu Iga ,  Shinichi Takimoto

IPC: A61B1/015 ,  A61B1/12 ,  A61B1/00 ,  A61B17/00 ,  A61M25/10 ,  A61M25/00 ,  A61B17/22

Abstract: A device for sustained release of optical clearing agent includes a stick-shaped component having at least two supplying passages for supplying gas or liquid formed on the inside with apertures of the supplying passages being formed at positions along the circumference of the lateral surface in the vicinity of the top end of the stick-shaped component respectively, at least two pouch-shaped elastic components placed at positions along the circumference of the lateral surface in the vicinity of the top end of the stick-shaped component respectively to cover the apertures of the supplying passages respectively, an optical clearing agent holding component fixed on the surface of one of the pouch-shaped elastic components and holding optical clearing agent, and a body-fluid absorbing component fixed on the surface of another one of the pouch-shaped elastic components and absorbing body fluid flowing from a target object or dehydrating the target object by osmotic pressure.

公开(公告)号：US20180179487A1

公开(公告)日：2018-06-28

申请号：US15848623

申请日：2017-12-20

Applicant: OLYMPUS CORPORATION

Inventor： Akira MATSUSHITA ,  Shintaro Takahashi ,  Masaru Mizunaka ,  Shinichi Takimoto ,  Tadashi Hirata ,  Yohei Tanikawa

IPC: C12M1/34 ,  H04N5/33 ,  H04N5/225 ,  G01J5/00 ,  G01J5/10

CPC classification number: C12M41/46 ,  G01J5/0003 ,  G01J5/04 ,  G01J5/061 ,  G01J5/0896 ,  G01J5/10 ,  G01J2005/0077 ,  G01J2005/068 ,  H04N5/2252 ,  H04N5/2256 ,  H04N5/33

Abstract: Provided is an observation apparatus including: a housing that has, in a top face thereof, a transmission window on which a container accommodating cells can be placed and through which light can pass; a camera portion that is accommodated in the housing and that captures observation light coming from the cells irradiated with illumination light emitted from an illumination portion and entering the housing by passing through a bottom face of the container and the transmission window of the housing; and a housing-interior heating portion that is accommodated in the housing and that heats the cells.

公开(公告)号：US12102306B2

公开(公告)日：2024-10-01

申请号：US17076003

申请日：2020-10-21

Applicant: OLYMPUS CORPORATION

Inventor： Ryosuke Ito ,  Yohei Tanikawa ,  Asuka Nakamura

IPC: A61B18/12 ,  A61B17/00 ,  A61B17/32 ,  A61B18/08 ,  A61B18/14 ,  A61B18/20 ,  A61B18/00

CPC classification number: A61B17/00234 ,  A61B17/320068 ,  A61B18/08 ,  A61B18/14 ,  A61B18/20 ,  A61B2017/00017 ,  A61B2017/00115 ,  A61B2017/00818 ,  A61B2017/320069 ,  A61B2018/0022 ,  A61B2018/00494 ,  A61B2018/00577

Abstract: A control device for an ablation treatment tool includes: a target-value storage unit that stores a target value for the total treatment area; an energy-source output unit that outputs, to the ablation treatment tool, an energy source for performing ablation treatment; an area calculation unit that calculates the total treatment area of the ileal mucosa on which the ablation treatment has been performed; and a control unit that controls termination of the ablation treatment performed by the ablation treatment tool. The control unit notifies an operator of the termination of the ablation treatment or stops the output of the energy source from the energy-source output unit when the calculated total treatment area of the ileal mucosa becomes equal to or greater than the target value.

公开(公告)号：US11226476B2

公开(公告)日：2022-01-18

申请号：US16366682

申请日：2019-03-27

Applicant: OLYMPUS CORPORATION

Inventor： Tsuyoshi Mochizuki ,  Shintaro Takahashi ,  Akira Matsushita ,  Yohei Tanikawa ,  Masaru Mizunaka ,  Shinichi Takimoto

IPC: G02B21/34 ,  G02B21/08 ,  G02B21/26 ,  G02B21/36 ,  G01N21/59 ,  G01N21/01 ,  G02B21/33 ,  G01N21/17 ,  C12M1/34

Abstract: An observation apparatus including: a top plate on which a container in which a specimen is accommodated can be placed, and through which illumination light can pass; a light source that emits the illumination light upward from below the specimen; an objective lens that focuses, below the specimen and the top plate, transmitted light which is the illumination light that has passed through the specimen from thereabove and that has passed through the top plate; and a camera that captures the transmitted light, wherein the light source emits the illumination light toward an area above the specimen from outside the objective lens in a radial direction, and the top plate is provided with a mark that specifies a viewing-field area of the camera.

公开(公告)号：US11137588B2

公开(公告)日：2021-10-05

申请号：US16364946

申请日：2019-03-26

Applicant: OLYMPUS CORPORATION

Inventor： Masaru Mizunaka ,  Shintaro Takahashi ,  Akira Matsushita ,  Yohei Tanikawa ,  Tsuyoshi Mochizuki ,  Shinichi Takimoto

IPC: G02B21/06 ,  G02B21/16 ,  G02B21/02 ,  G02B21/12 ,  G01N21/64 ,  G02B21/36 ,  G02B21/10 ,  G01N21/17 ,  G02B21/24 ,  G02B21/33

Abstract: An observation apparatus including: a light-source that emits illumination light and excitation light upward from below a specimen; and an image-capturing optical system having an objective lens that focuses, below the specimen, transmitted light, which is the illumination light that is emitted from the light-source, that is reflected above the specimen, and that has passed through the specimen, and fluorescence that is generated in the specimen that has been irradiated with the excitation light emitted from the light-source, wherein the light-source is disposed radially outside the objective lens.

公开(公告)号：US11759098B2

公开(公告)日：2023-09-19

申请号：US17086527

申请日：2020-11-02

Applicant: OLYMPUS CORPORATION

Inventor： Jumpei Takahashi ,  Ryosuke Ito ,  Yohei Tanikawa ,  Takayuki Tsukagoshi ,  Yuki Shono

IPC: A61B1/06 ,  A61B1/045 ,  A61B1/00 ,  A61B1/05

CPC classification number: A61B1/0638 ,  A61B1/00006 ,  A61B1/000094 ,  A61B1/045 ,  A61B1/05 ,  A61B1/0655 ,  A61B1/0661

Abstract: An endoscope apparatus including: a light source configured to emit illumination light including light in a first wavelength band included in a blue wavelength band, light in a first narrowband included in a green wavelength band, and light in a second narrowband having a same light absorption coefficient of hemoglobin as that of the light in the first narrowband; an imager configured to acquire a first image of an object in the first wavelength band, a first narrowband image of the object in the first narrowband, and a second narrowband image of the object in the second narrowband; and a processor including hardware. The processor is configured to implement acquiring scattering characteristics information based on a comparison result between the first narrowband image and the second narrowband image, and generating an observation image using the first image, the first narrowband image, and the scattering characteristics information.

公开(公告)号：US11194145B2

公开(公告)日：2021-12-07

申请号：US16677809

申请日：2019-11-08

Applicant: OLYMPUS CORPORATION

Inventor： Yohei Tanikawa ,  Shinichi Takimoto ,  Masakazu Fujii ,  Taiji Mine ,  Takayuki Nakatomi

IPC: G02B21/00 ,  G02B21/36

Abstract: An image reproducing device includes one or more processors. The processor acquires image group data including a plurality of images and tag information on at least one tag. The images relate to a biological sample along time series. The tag information relates to an operation on the biological sample and is associated with at least part of the images. The processor selects from the plurality of images using the tag information, images to be reproduced along the time series as reproduction selected images. The processor outputs to a display, data relating to the images for the reproduction selected images to be reproduced along time series.

公开(公告)号：US11037293B2

公开(公告)日：2021-06-15

申请号：US16458397

申请日：2019-07-01

Applicant: OLYMPUS CORPORATION

Inventor： Naohiro Ariga ,  Shintaro Takahashi ,  Yohei Tanikawa ,  Shinichi Takimoto

IPC: G06T7/00 ,  G01N33/483 ,  G06F17/18

Abstract: A cell observation system includes an imaging element that acquires images of the inside of a culture container in which cells are cultured, the imaging element acquiring the images over time; a computer configured to: quantitatively analyze a culture state of the cells cultured in the culture container on the basis of each of the images acquired by the imaging element; and statistically analyze the quantitatively analyzed data; and a display that displays statistical analysis results in the culture container within a plurality of subculture periods obtained by the computer in a manner allowing comparison of the statistical analysis results.