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公开(公告)号：US20150344833A1
公开(公告)日：2015-12-03
申请号：US14721174
申请日：2015-05-26
Applicant: OLYMPUS CORPORATION
Inventor： Hiroyuki KIMURA , Tatsuya MINAMI , Yasunori MAKARA
CPC classification number: C12M29/26 , C12M23/14 , C12M23/48 , C12M25/02 , C12M29/14 , C12M41/12 , C12M41/40 , C12M41/48 , F04F3/00
Abstract: Supply and discharge of a solution, such as a medium, in a cell culture bag are easily controlled. Provided is a system including a sac-like cell culture bag having a supply port for supplying a solution, such as a medium, to the inside and having a discharge port for discharging the solution, such as a medium, from the inside, wherein gate opening and closing means for opening and closing inner holes of the supply port and the discharge port are attached to the supply port and the discharge port, and the gate opening and closing means are controlled to easily exchange the medium or the like in the cell culture bag.
Abstract translation: 容易地控制细胞培养袋中的溶液如培养基的供应和排出。 本发明提供一种系统，其包括囊状细胞培养袋，其具有用于向内部供给溶液的供给口（例如介质），并具有用于从内部排出介质的溶液的排出口，其中，门 用于打开和关闭供给口和排出口的内孔的打开和关闭装置附接到供给口和排出口，并且控制门开闭装置以容易地更换细胞培养物中的介质等 袋。
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2.发明申请公开(公告)号：US20170337683A1
公开(公告)日：2017-11-23
申请号：US15593384
申请日：2017-05-12
Applicant: OLYMPUS CORPORATION
Inventor： Hideaki YOSHIDA , Masayasu CHIDA , Ryo KOSHIDA , Yasunori MAKARA , Osamu ONO , Osamu NONAKA
CPC classification number: A61B10/0283 , A61B10/06 , G06F19/00 , G06F19/321
Abstract: A image file creation method includes: an image pickup step of picking up an image of a living body; a treatment detection step of detecting a treatment related to the living body; and an image file creation step of creating, according to a result of the detection in the treatment detection step, an image file, for image data obtained in the image pickup step, with specimen information including information indicating that the image is an image relating to specimen collection by the treatment related to the living body, to record data of, e.g., an image of a tissue such as a cell itself and data of, e.g., an image related to the tissue such as the cell, a treatment and/or collection, enabling a plurality of institutions, facilities, etc., to easily refer to information on the tissue such as the cell.
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公开(公告)号：US20170226465A1
公开(公告)日：2017-08-10
申请号：US15495435
申请日：2017-04-24
Applicant: OLYMPUS CORPORATION
Inventor： Hiroyuki KIMURA , Tatsuya MINAMI , Yasunori MAKARA
Abstract: A cell culture system of the present invention includes: a culture-medium storage part that holds a culture medium for culturing cells; a temporary holding part that is coupled to the culture-medium storage part and that is provided with a holding space for temporarily holding the culture medium supplied from the culture-medium storage part and a discharge port for discharging the culture medium; a culture-medium supply part that is coupled to the discharge port of the temporary holding part and that supplies the culture medium discharged from the temporary holding part, to a cell culture vessel; and a discharge part that discharges the culture medium from the cell culture vessel, wherein the culture-medium supply part is provided with a culture-medium intermittent supply mechanism that intermittently supplies the culture medium discharged from the temporary holding part, to the cell culture vessel in a predetermined cycle.
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公开(公告)号：US20180320120A1
公开(公告)日：2018-11-08
申请号：US16031312
申请日：2018-07-10
Applicant: OLYMPUS CORPORATION
Inventor： Hiroyuki KIMURA , Tatsuya MINAMI , Yasunori MAKARA
CPC classification number: C12M1/36 , B01L1/00 , B01L2300/02 , B01L2300/0861 , B01L2400/0457 , C12M3/00 , C12M23/02 , C12M23/42 , C12M29/00 , C12M41/32 , C12M41/44
Abstract: A cell culture container includes, in sequence from above in the gravity direction: a culture-medium holding container; a cell holding container that holds cells and a culture medium supplied from the culture-medium holding container through a supply port provided in the top surface thereof; a waste-liquid holding container that holds the culture medium discharged from the cell holding container; and a discharge mechanism for discharging the culture medium that has exceeded a predetermined level from the cell holding container to the waste-liquid holding container.
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公开(公告)号：US20180291328A1
公开(公告)日：2018-10-11
申请号：US16006399
申请日：2018-06-12
Applicant: OLYMPUS CORPORATION
Inventor： Hiroshi SASAKI , Tatsuya MINAMI , Yasunori MAKARA
Abstract: Provided is a cell-culturing apparatus including: an incubator that can maintain an interior thereof in an environment that is appropriate for growth of cells; a cell-culturing vessel that is accommodated inside the incubator; an optical-data acquisition unit that acquires optical data of a medium in the cell-culturing vessel; a medium changing unit that changes the medium in the cell-culturing vessel; and a controller, wherein a timing at which the medium is changed is determined on the basis of a change over time in the optical data acquired by the optical-data acquisition unit.
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Patent Agency Ranking
公开(公告)号：US20170137771A1
公开(公告)日：2017-05-18
申请号：US15341449
申请日：2016-11-02
Applicant: OLYMPUS CORPORATION
Inventor： Hiroyuki KIMURA , Tatsuya MINAMI , Yasunori MAKARA
IPC: C12M1/00
CPC classification number: C12M41/14
Abstract: A cell culture apparatus of the present invention includes: a body including a space for accommodating a culture container, and an opening through which the culture container is taken in and out; a door that opens and closes the opening; an optical detection unit that includes optical sensors that optically detects an instruction to open and close the opening from a user, and converts the detection by the optical sensors to a signal and sends the signal; and a door open/close unit that receives the signal from the optical detection unit and controls open/close of the opening by the door.
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公开(公告)号：US20170037352A1
公开(公告)日：2017-02-09
申请号：US15214660
申请日：2016-07-20
Applicant: OLYMPUS CORPORATION
Inventor： Hiroyuki KIMURA , Tatsuya MINAMI , Yasunori MAKARA
Abstract: A cell culture apparatus includes a culture tank having an inlet and an outlet, a culture-medium supplying unit that supplies a culture medium to the culture tank through the inlet, and a culture-medium discharging unit that discharges the culture medium through the outlet. The culture tank includes a division wall that can divide the internal space in a direction of gravity into an upper space and a lower space. The outlet opens into the upper space, and the division wall enables switching between a state where the internal space of the culture tank is divided into the upper space and the lower space and a state where the upper space and the lower space are in communication with each other.
Abstract translation: 细胞培养装置包括具有入口和出口的培养罐，通过入口向培养槽供给培养基的培养基供给单元和通过出口排出培养基的培养基排出单元。 培养罐包括分隔壁，其可以将重力方向的内部空间分成上部空间和下部空间。 出口通向上部空间，分隔壁能够在将培养罐的内部空间分成上部空间和下部空间的状态与上部空间和下部空间与下部空间连通的状态 彼此。
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公开(公告)号：US20170327782A1
公开(公告)日：2017-11-16
申请号：US15666551
申请日：2017-08-01
Applicant: OLYMPUS CORPORATION
Inventor： Hiroyuki KIMURA , Tatsuya MINAMI , Yasunori MAKARA
CPC classification number: C12M37/04 , C12M23/34 , C12M23/52 , C12M29/00 , C12M33/00 , C12M41/00 , C12M41/14
Abstract: Provided is a cell-culturing apparatus including a culturing unit in which a culturing vessel is placed and an incubator in which a plurality of culturing units are placed in an interior thereof, and that can maintain the interior thereof at an environment that is appropriate for cell culturing, wherein the incubator includes openings that are provided for each of the plurality of culturing units and through which the culturing units can separately be moved into and out of the incubator, and closing means that are provided at the openings and that seals off the internal environment of the incubator from outside when the culturing unit is taken out of the incubator.
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公开(公告)号：US20170158996A1
公开(公告)日：2017-06-08
申请号：US15431153
申请日：2017-02-13
Applicant: OLYMPUS CORPORATION
Inventor： Hiroyuki KIMURA , Tatsuya MINAMI , Yasunori MAKARA
Abstract: A cell culture apparatus according to the present invention includes a cell culture bag and a culture tank. The cell culture bag is composed of a bag-shaped film material capable of accommodating cells and a culture medium therein. At least a part of the bag-shaped film material is formed of a porous membrane that selectively allows a substance contained in the culture medium to pass through but does not allow the cells to pass through. The culture tank retains the cell culture bag in an immersed state in a solution.
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公开(公告)号：US20170107475A1
公开(公告)日：2017-04-20
申请号：US15391804
申请日：2016-12-27
Applicant: OLYMPUS CORPORATION
Inventor： Hiroyuki KIMURA , Tatsuya MINAMI , Yasunori MAKARA
Abstract: A cell-culturing system includes: a solution-holding means holding a medium; and a solution-supplying means supplying the solution supplied thereto from the solution-holding means to a cell-culturing container. The solution-supplying means may supply a solution to the container via a solution dripping step. The container may be connected to the solution-supplying means at a position that is lower than the solution-supplying means in a direction in which gravity acts; the solution-supplying means may have a space in which the solution supplied thereto from the solution-holding means is made to drip; the system may be provided with a discharging port discharging the solution at a position in a container side surface at a desired height; and the solution may be discharged outside when the height of a top surface of the solution in the container reaches the port as a result of supplying the solution to the container from the solution-supplying means.
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