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公开(公告)号：US11208464B2
公开(公告)日：2021-12-28
申请号：US16412819
申请日：2019-05-15
Applicant: Janssen Biotech, Inc.
Inventor： Anthony Armstrong , Judith Ann Connor , Jennifer Furman , Chichi Huang , Michael J. Hunter , Xiefan Lin-Schmidt , Serena Nelson , Shamina M. Rangwala , Shannon Mullican , Jose Antonio Chavez
IPC: A61K38/19 , A61K38/17 , A61K38/18 , A61K38/16 , A61K38/00 , C07K14/765 , C07K14/51 , C07K14/47 , C07K14/435 , C07K14/46 , C12N5/12 , C12N15/00 , C12N15/11 , C12N15/63 , C12N15/09 , C12N15/62 , C07K14/475
Abstract: Fusion proteins containing a half-life extension protein, a linker, and a GDF15 protein are described. Also described are nucleic acids encoding the fusion proteins, recombinant cells thereof, compositions comprising the fusion proteins, and methods of using the fusion proteins for treating or preventing metabolic diseases, disorders or conditions.
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公开(公告)号：US10208113B2
公开(公告)日：2019-02-19
申请号：US14745939
申请日：2015-06-22
Applicant: Janssen Biotech, Inc.
Inventor： Ellen Chi , Judith Connor , Chichi Huang , Jarrat Jordan , Xiefan Lin-Schmidt , Jinquan Luo , Lu Lu , Christian Martinez , Galina Obmolova , Ronald Swanson
Abstract: The present invention relates to antibodies that broady neutralize interferon-α and interferon-ω, polynucleotides encoding the antibodies or fragments, and methods of making and using the foregoing.
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公开(公告)号：US09902770B2
公开(公告)日：2018-02-27
申请号：US14208861
申请日：2014-03-13
Applicant: Janssen Biotech, Inc.
Inventor： Ellen Chi , Judith Connor , Chichi Huang , Jarrat Jordan , Xiefan Lin-Schmidt , Jinquan Luo , Lu Lu , Christian Martinez , Galina Obmolova , Ronald Swanson
IPC: C07K16/24 , C07K16/46 , A61K39/395
CPC classification number: C07K16/249 , C07K2317/21 , C07K2317/31 , C07K2317/33 , C07K2317/34 , C07K2317/76 , C07K2317/92
Abstract: Broadly neutralizing interferon-α and interferon-ω antibody antagonists, polynucleotides encoding the antibodies or fragments, and methods of making and using the foregoing are useful in the treatment of diseases associated with increased production of IFNα and IFNω.
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公开(公告)号：US20150368338A1
公开(公告)日：2015-12-24
申请号：US14745939
申请日：2015-06-22
Applicant: Janssen Biotech, Inc.
Inventor： Ellen Chi , Judith Connor , Chichi Huang , Jarrat Jordan , Xiefan Lin-Schmidt , Jinquan Luo , Lu Lu , Christian Martinez , Galina Obmolova , Ronald Swanson
IPC: C07K16/24 , A61K45/06 , A61K39/395
CPC classification number: C07K16/249 , A61K38/13 , A61K39/3955 , A61K45/06 , A61K2039/505 , A61K2039/507 , C07K2317/21 , C07K2317/31 , C07K2317/33 , C07K2317/52 , C07K2317/55 , C07K2317/565 , C07K2317/76 , C07K2317/92 , A61K2300/00
Abstract: The present invention relates to antibodies that broady neutralize interferon-α and interferon-ω, polynucleotides encoding the antibodies or fragments, and methods of making and using the foregoing.
Abstract translation: 本发明涉及广泛中和干扰素-α和干扰素-ω，编码抗体或片段的多核苷酸的抗体，以及制备和使用前述物质的方法。
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公开(公告)号：US11603405B2
公开(公告)日：2023-03-14
申请号：US16418082
申请日：2019-05-21
Applicant: Janssen Biotech, Inc.
Inventor： Francois Gaudet , Jill Giles-Komar , Bradley Heidrich , Chichi Huang , Colleen Kane , Ronan McDaid , Jennifer Nemeth-Seay
IPC: C07K16/28 , A61P35/00 , A61K39/395 , C07K16/30 , A61K39/00
Abstract: The present invention relates to antibodies that specifically bind CD3. The present invention relates to antibodies that specifically bind PSMA. The present invention relates to antibodies that specifically bind CD3 and PSMA. The present invention relates to antibodies that specifically bind IL1RAP. The present invention relates to antibodies that specifically bind CD33. The present invention relates to antibodies that specifically bind CD3 and IL1RAP. The present invention relates to antibodies that specifically bind CD3 and CD33. The present invention relates to antibodies that specifically bind TMEFF2. The present invention relates to antibodies that specifically bind CD3 and TMEFF2. The present invention relates to fragments of the antibodies, polynucleotides encoding the antibodies or fragments thereof, and methods of making and using the same.
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Patent Agency Ranking
公开(公告)号：US20210047435A1
公开(公告)日：2021-02-18
申请号：US16994065
申请日：2020-08-14
Applicant: Janssen Biotech, Inc.
Inventor： Jinquan Luo , Lauren Boucher , Michael Feldkamp , Michael Diem , Anthony A. Armstrong , Alexey Teplyakov , Chichi Huang
IPC: C07K16/42 , C07K14/705
Abstract: Disclosed are materials and methods for improved single chain variable fragments.
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公开(公告)号：US20190135912A1
公开(公告)日：2019-05-09
申请号：US16184270
申请日：2018-11-08
Applicant: Janssen Biotech, Inc.
Inventor： Ellen Chi , Judith Connor , Chichi Huang , Jarrat Jordan , Xiefan Lin-Schmidt , Jinquan Luo , Lu Lu , Christian Martinez , Galina Obmolova , Ronald Swanson
IPC: C07K16/24
Abstract: Broadly neutralizing interferon-α and interferon-ω antibody antagonists, polynucleotides encoding the antibodies or fragments, and methods of making and using the foregoing are usefule in the treatment of diseases associated with increased production of IFNα and IFNω.
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公开(公告)号：US20190106489A1
公开(公告)日：2019-04-11
申请号：US16222285
申请日：2018-12-17
Applicant: Janssen Biotech, Inc.
Inventor： Ellen Chi , Judith Connor , Chichi Huang , Jarrat Jordan , Xiefan Lin-Schmidt , Jinquan Luo , Lu Lu , Christian Martinez , Galina Obmolova , Ronald Swanson
CPC classification number: C07K16/249 , A61K38/13 , A61K39/3955 , A61K45/06 , A61K2039/505 , A61K2039/507 , C07K2317/21 , C07K2317/31 , C07K2317/33 , C07K2317/52 , C07K2317/55 , C07K2317/565 , C07K2317/76 , C07K2317/92 , A61K2300/00
Abstract: The present invention relates to antibodies that broady neutralize interferon-α and interferon-ω, polynucleotides encoding the antibodies or fragments, and methods of making and using the foregoing.
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9.发明申请公开(公告)号：US20220127343A1
公开(公告)日：2022-04-28
申请号：US17493032
申请日：2021-10-04
Applicant: Janssen Biotech, Inc.
Inventor： Chichi Huang , John Lee , Jill Mooney , Michael Naso
IPC: C07K16/18
Abstract: Fibronectin type III (FN3) domain antibodies, polynucleotides capable of encoding the FN3 domain antibodies or antigen-binding fragments, cells expressing FN3 domain antibodies or antigen-binding fragments, as well as associated vectors and detectably labeled FN3 domain antibodies or antigen-binding fragments may be used to engineer FN3 domain-targeting chimeric antigen receptors (CARs). Methods of making the FN3 domain antibodies, CARs, and engineered immune cells, and methods of using the engineered immune cells are applicable to treat diseases including cancer.
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公开(公告)号：US20190359705A1
公开(公告)日：2019-11-28
申请号：US16424907
申请日：2019-05-29
Applicant: Janssen Biotech, Inc.
Inventor： Ellen Chi , Judith Connor , Chichi Huang , Jarrat Jordan , Xiefan Lin-Schmidt , Jinquan Luo , Lu Lu , Christian Martinez , Galina Obmolova , Ronald Swanson
Abstract: The present invention relates to antibodies that broady neutralize interferon-α and interferon-ω, polynucleotides encoding the antibodies or fragments, and methods of making and using the foregoing.
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