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公开(公告)号：US20170327560A1
公开(公告)日：2017-11-16
申请号：US15586463
申请日：2017-05-04
Applicant: Janssen Biotech, Inc.
Inventor： Anthony Armstrong , Judith Ann Connor , Jennifer Furman , Chichi Huang , Michael J. Hunter , Xiefan Lin-Schmidt , Serena Nelson , Shamina Rangwala , Shannon Mullican , Jose Antonio Chavez
IPC: C07K14/765 , C07K14/475 , A61K38/00
CPC classification number: C07K14/765 , A61K38/00 , A61K38/16 , A61K38/17 , A61K38/18 , A61K38/1875 , A61K38/19 , C07K14/435 , C07K14/46 , C07K14/47 , C07K14/475 , C07K14/51 , C07K2319/31 , C12N5/12 , C12N15/00 , C12N15/09 , C12N15/11 , C12N15/62 , C12N15/63
Abstract: Fusion proteins containing a half-life extension protein, a linker, and a GDF15 protein are described. Also described are nucleic acids encoding the fusion proteins, recombinant cells thereof, compositions comprising the fusion proteins, and methods of using the fusion proteins for treating or preventing metabolic diseases, disorders or conditions.
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公开(公告)号：US10336812B2
公开(公告)日：2019-07-02
申请号：US15586463
申请日：2017-05-04
Applicant: Janssen Biotech, Inc.
Inventor： Anthony Armstrong , Judith Ann Connor , Jennifer Furman , Chichi Huang , Michael J. Hunter , Xiefan Lin-Schmidt , Serena Nelson , Shamina Rangwala , Shannon Mullican , Jose Antonio Chavez
IPC: A61K38/00 , A61K38/16 , A61K38/17 , A61K38/18 , A61K38/19 , C07K14/00 , C07K14/435 , C07K14/46 , C07K14/47 , C07K14/475 , C07K14/51 , C07K14/765 , C12N1/11 , C12N1/13 , C12N1/15 , C12N1/21 , C12N5/10 , C12N15/00 , C12N15/09 , C12N15/11 , C12N15/12 , C12N15/14 , C12N15/62 , C12N15/63 , C12N5/12
Abstract: Fusion proteins containing a half-life extension protein, a linker, and a GDF15 protein are described. Also described are nucleic acids encoding the fusion proteins, recombinant cells thereof, compositions comprising the fusion proteins, and methods of using the fusion proteins for treating or preventing metabolic diseases, disorders or conditions.
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公开(公告)号：US20190292241A1
公开(公告)日：2019-09-26
申请号：US16412819
申请日：2019-05-15
Applicant: Janssen Biotech, Inc.
Inventor： Anthony Armstrong , Judith Ann Connor , Jennifer Furman , Chichi Huang , Michael J. Hunter , Xiefan Lin-Schmidt , Serena Nelson , Shamina M. Rangwala , Shannon Mullican , Jose Antonio Chavez
IPC: C07K14/765 , C12N15/62 , C12N15/09 , C07K14/475 , C12N15/63 , C12N15/11 , C12N15/00 , C12N5/12 , C07K14/46 , A61K38/16 , C07K14/435 , A61K38/18 , C07K14/47 , C07K14/51 , A61K38/17 , A61K38/19
Abstract: Fusion proteins containing a half-life extension protein, a linker, and a GDF15 protein are described. Also described are nucleic acids encoding the fusion proteins, recombinant cells thereof, compositions comprising the fusion proteins, and methods of using the fusion proteins for treating or preventing metabolic diseases, disorders or conditions.
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公开(公告)号：US11208464B2
公开(公告)日：2021-12-28
申请号：US16412819
申请日：2019-05-15
Applicant: Janssen Biotech, Inc.
Inventor： Anthony Armstrong , Judith Ann Connor , Jennifer Furman , Chichi Huang , Michael J. Hunter , Xiefan Lin-Schmidt , Serena Nelson , Shamina M. Rangwala , Shannon Mullican , Jose Antonio Chavez
IPC: A61K38/19 , A61K38/17 , A61K38/18 , A61K38/16 , A61K38/00 , C07K14/765 , C07K14/51 , C07K14/47 , C07K14/435 , C07K14/46 , C12N5/12 , C12N15/00 , C12N15/11 , C12N15/63 , C12N15/09 , C12N15/62 , C07K14/475
Abstract: Fusion proteins containing a half-life extension protein, a linker, and a GDF15 protein are described. Also described are nucleic acids encoding the fusion proteins, recombinant cells thereof, compositions comprising the fusion proteins, and methods of using the fusion proteins for treating or preventing metabolic diseases, disorders or conditions.
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