公开(公告)号：US20230322924A1

公开(公告)日：2023-10-12

申请号：US18180225

申请日：2023-03-08

Applicant: Janssen Biotech, Inc.

Inventor： Francois Gaudet ,  Jill Giles-Komar ,  Bradley Heidrich ,  Chichi Huang ,  Colleen Kane ,  Ronan Mcdaid ,  Jennifer Nemeth-Seay

IPC: C07K16/28 ,  A61P35/00 ,  A61K39/395 ,  C07K16/30

CPC classification number: C07K16/2809 ,  A61P35/00 ,  A61K39/39541 ,  C07K16/28 ,  C07K16/2803 ,  C07K16/3069 ,  A61K2039/505

Abstract: The present invention relates to antibodies that specifically bind CD3. The present invention relates to antibodies that specifically bind PSMA. The present invention relates to antibodies that specifically bind CD3 and PSMA. The invention relates to antibodies that specifically bind IL1RAP. The present invention relates to antibodies that specifically bind CD33. The present invention relates to antibodies that specifically bind CD3 and IL1RAP. The present invention relates to antibodies that specifically bind CD3 and CD33. The present invention relates to antibodies that specifically bind TMEFF2. The present invention relates to antibodies that specifically bind CD3 and TMEFF2. The present invention relates to fragments of the antibodies, polynucleotides encoding the antibodies or fragments thereof, and methods of making and using the same.

公开(公告)号：US11866499B2

公开(公告)日：2024-01-09

申请号：US16417889

申请日：2019-05-21

Applicant: Janssen Biotech, Inc.

Inventor： Philip Cooper ,  Robin Ernst ,  Rajkumar Ganesan ,  Colleen Kane ,  Michael Russell ,  Sanjaya Singh ,  Sathyadevi Venkataramani ,  Sheng-Jiun Wu

IPC: C07K16/28 ,  A61P35/00 ,  A61K45/06

CPC classification number: C07K16/2809 ,  A61P35/00 ,  A61K45/06

Abstract: The disclosure provided herein relates to monospecific and multispecific anti-TMEFF2 antibodies, and methods of producing and using the described antibodies.

公开(公告)号：US11603405B2

公开(公告)日：2023-03-14

申请号：US16418082

申请日：2019-05-21

Applicant: Janssen Biotech, Inc.

Inventor： Francois Gaudet ,  Jill Giles-Komar ,  Bradley Heidrich ,  Chichi Huang ,  Colleen Kane ,  Ronan McDaid ,  Jennifer Nemeth-Seay

IPC: C07K16/28 ,  A61P35/00 ,  A61K39/395 ,  C07K16/30 ,  A61K39/00

Abstract: The present invention relates to antibodies that specifically bind CD3. The present invention relates to antibodies that specifically bind PSMA. The present invention relates to antibodies that specifically bind CD3 and PSMA. The present invention relates to antibodies that specifically bind IL1RAP. The present invention relates to antibodies that specifically bind CD33. The present invention relates to antibodies that specifically bind CD3 and IL1RAP. The present invention relates to antibodies that specifically bind CD3 and CD33. The present invention relates to antibodies that specifically bind TMEFF2. The present invention relates to antibodies that specifically bind CD3 and TMEFF2. The present invention relates to fragments of the antibodies, polynucleotides encoding the antibodies or fragments thereof, and methods of making and using the same.

公开(公告)号：US11746157B2

公开(公告)日：2023-09-05

申请号：US16418328

申请日：2019-05-21

Applicant: Janssen Biotech, Inc.

Inventor： Glenn Mark Anderson ,  Tammy Bush ,  Rosa Maria Fernandes Cardoso ,  Ellen Chi ,  Judith Ann Connor ,  Thai Quang Dinh ,  Derrick Lemon Domingo ,  John Michael Jones ,  Colleen Kane ,  Bethany Kay Mattson ,  Theresa Marie McDevitt ,  Jill Marie Mooney ,  Richard Stephen Tawadros ,  Hong Mimi Zhou

IPC: C07K16/30 ,  C07K16/28

CPC classification number: C07K16/3069 ,  C07K16/2809 ,  C07K2317/21 ,  C07K2317/31 ,  C07K2317/515 ,  C07K2317/565 ,  C07K2317/76 ,  C07K2317/92

Abstract: The present invention relates to antibodies specifically binding PSMA or PSMA and CD3, polynucleotides encoding the antibodies or fragments, and methods of making and using the foregoing.

公开(公告)号：US20250109198A1

公开(公告)日：2025-04-03

申请号：US18797622

申请日：2024-08-08

Applicant: Janssen Biotech, Inc.

Inventor： Christoph Heuck ,  Colleen Kane ,  Marie-Anne Damiette Smit

IPC: C07K16/28 ,  A61K39/00

Abstract: Described herein are approved products and methods of using approved products for treating relapsed or refractory multiple myeloma in a patient. Also described herein are methods of selling or offering for sale an approved product.

公开(公告)号：US20200024360A1

公开(公告)日：2020-01-23

申请号：US16418328

申请日：2019-05-21

Applicant: Janssen Biotech, Inc.

Inventor： Glenn Mark Anderson ,  Tammy Bush ,  Rosa Maria Fernandes Cardoso ,  Ellen Chi ,  Judith Ann Connor ,  Thai Quang Dinh ,  Derrick Lemon Domingo ,  John Michael Jones ,  Colleen Kane ,  Bethany Kay Mattson ,  Theresa Marie McDevitt ,  Jill Marie Mooney ,  Richard Stephen Tawadros ,  Hong Mimi Zhou

IPC: C07K16/30 ,  C07K16/28

Abstract: The present invention relates to antibodies specifically binding PSMA or PSMA and CD3, polynucleotides encoding the antibodies or fragments, and methods of making and using the foregoing.