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公开(公告)号:US10155809B2
公开(公告)日:2018-12-18
申请号:US15707317
申请日:2017-09-18
Applicant: Janssen Biotech, Inc.
Inventor: Ellen Chi , Judith Connor , Chichi Huang , Jarrat Jordan , Xiefan Lin-Schmidt , Jinquan Luo , Lu Lu , Christian Martinez , Galina Obmolova , Ronald Swanson
Abstract: Broadly neutralizing interferon-α and interferon-ω antibody antagonists, polynucleotides encoding the antibodies or fragments, and methods of making and using the foregoing are useful in the treatment of diseases associated with increased production of IFNα and IFNω.
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公开(公告)号:US10759854B2
公开(公告)日:2020-09-01
申请号:US16424907
申请日:2019-05-29
Applicant: Janssen Biotech, Inc.
Inventor: Ellen Chi , Judith Connor , Chichi Huang , Jarrat Jordan , Xiefan Lin-Schmidt , Jinquan Luo , Lu Lu , Christian Martinez , Galina Obmolova , Ronald Swanson
IPC: C07K16/24 , A61K38/13 , A61K45/06 , A61K39/395 , A61K39/00
Abstract: The present invention relates to antibodies that broady neutralize interferon-α and interferon-ω, polynucleotides encoding the antibodies or fragments, and methods of making and using the foregoing.
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公开(公告)号:US20190135912A1
公开(公告)日:2019-05-09
申请号:US16184270
申请日:2018-11-08
Applicant: Janssen Biotech, Inc.
Inventor: Ellen Chi , Judith Connor , Chichi Huang , Jarrat Jordan , Xiefan Lin-Schmidt , Jinquan Luo , Lu Lu , Christian Martinez , Galina Obmolova , Ronald Swanson
IPC: C07K16/24
Abstract: Broadly neutralizing interferon-α and interferon-ω antibody antagonists, polynucleotides encoding the antibodies or fragments, and methods of making and using the foregoing are usefule in the treatment of diseases associated with increased production of IFNα and IFNω.
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公开(公告)号:US20190106489A1
公开(公告)日:2019-04-11
申请号:US16222285
申请日:2018-12-17
Applicant: Janssen Biotech, Inc.
Inventor: Ellen Chi , Judith Connor , Chichi Huang , Jarrat Jordan , Xiefan Lin-Schmidt , Jinquan Luo , Lu Lu , Christian Martinez , Galina Obmolova , Ronald Swanson
CPC classification number: C07K16/249 , A61K38/13 , A61K39/3955 , A61K45/06 , A61K2039/505 , A61K2039/507 , C07K2317/21 , C07K2317/31 , C07K2317/33 , C07K2317/52 , C07K2317/55 , C07K2317/565 , C07K2317/76 , C07K2317/92 , A61K2300/00
Abstract: The present invention relates to antibodies that broady neutralize interferon-α and interferon-ω, polynucleotides encoding the antibodies or fragments, and methods of making and using the foregoing.
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公开(公告)号:US10208113B2
公开(公告)日:2019-02-19
申请号:US14745939
申请日:2015-06-22
Applicant: Janssen Biotech, Inc.
Inventor: Ellen Chi , Judith Connor , Chichi Huang , Jarrat Jordan , Xiefan Lin-Schmidt , Jinquan Luo , Lu Lu , Christian Martinez , Galina Obmolova , Ronald Swanson
Abstract: The present invention relates to antibodies that broady neutralize interferon-α and interferon-ω, polynucleotides encoding the antibodies or fragments, and methods of making and using the foregoing.
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公开(公告)号:US09902770B2
公开(公告)日:2018-02-27
申请号:US14208861
申请日:2014-03-13
Applicant: Janssen Biotech, Inc.
Inventor: Ellen Chi , Judith Connor , Chichi Huang , Jarrat Jordan , Xiefan Lin-Schmidt , Jinquan Luo , Lu Lu , Christian Martinez , Galina Obmolova , Ronald Swanson
IPC: C07K16/24 , C07K16/46 , A61K39/395
CPC classification number: C07K16/249 , C07K2317/21 , C07K2317/31 , C07K2317/33 , C07K2317/34 , C07K2317/76 , C07K2317/92
Abstract: Broadly neutralizing interferon-α and interferon-ω antibody antagonists, polynucleotides encoding the antibodies or fragments, and methods of making and using the foregoing are useful in the treatment of diseases associated with increased production of IFNα and IFNω.
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公开(公告)号:US20150368338A1
公开(公告)日:2015-12-24
申请号:US14745939
申请日:2015-06-22
Applicant: Janssen Biotech, Inc.
Inventor: Ellen Chi , Judith Connor , Chichi Huang , Jarrat Jordan , Xiefan Lin-Schmidt , Jinquan Luo , Lu Lu , Christian Martinez , Galina Obmolova , Ronald Swanson
IPC: C07K16/24 , A61K45/06 , A61K39/395
CPC classification number: C07K16/249 , A61K38/13 , A61K39/3955 , A61K45/06 , A61K2039/505 , A61K2039/507 , C07K2317/21 , C07K2317/31 , C07K2317/33 , C07K2317/52 , C07K2317/55 , C07K2317/565 , C07K2317/76 , C07K2317/92 , A61K2300/00
Abstract: The present invention relates to antibodies that broady neutralize interferon-α and interferon-ω, polynucleotides encoding the antibodies or fragments, and methods of making and using the foregoing.
Abstract translation: 本发明涉及广泛中和干扰素-α和干扰素-ω,编码抗体或片段的多核苷酸的抗体,以及制备和使用前述物质的方法。
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公开(公告)号:US20190359705A1
公开(公告)日:2019-11-28
申请号:US16424907
申请日:2019-05-29
Applicant: Janssen Biotech, Inc.
Inventor: Ellen Chi , Judith Connor , Chichi Huang , Jarrat Jordan , Xiefan Lin-Schmidt , Jinquan Luo , Lu Lu , Christian Martinez , Galina Obmolova , Ronald Swanson
Abstract: The present invention relates to antibodies that broady neutralize interferon-α and interferon-ω, polynucleotides encoding the antibodies or fragments, and methods of making and using the foregoing.
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公开(公告)号:US10358491B2
公开(公告)日:2019-07-23
申请号:US16222285
申请日:2018-12-17
Applicant: Janssen Biotech, Inc.
Inventor: Ellen Chi , Judith Connor , Chichi Huang , Jarrat Jordan , Xiefan Lin-Schmidt , Jinquan Luo , Lu Lu , Christian Martinez , Galina Obmolova , Ronald Swanson
Abstract: The present invention relates to antibodies that broady neutralize interferon-α and interferon-ω, polynucleotides encoding the antibodies or fragments, and methods of making and using the foregoing.
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公开(公告)号:US20180002418A1
公开(公告)日:2018-01-04
申请号:US15707317
申请日:2017-09-18
Applicant: Janssen Biotech, Inc.
Inventor: Ellen Chi , Judith Connor , Chichi Huang , Jarrat Jordan , Xiefan Lin-Schmidt , Jinquan Luo , Lu Lu , Christian Martinez , Galina Obmolova , Ronald Swanson
IPC: C07K16/24
CPC classification number: C07K16/249 , C07K2317/21 , C07K2317/31 , C07K2317/33 , C07K2317/34 , C07K2317/76 , C07K2317/92
Abstract: Broadly neutralizing interferon-α and interferon-ω antibody antagonists, polynucleotides encoding the antibodies or fragments, and methods of making and using the foregoing are useful in the treatment of diseases associated with increased production of IFNα and IFNω.
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