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公开(公告)号：US5895370A
公开(公告)日：1999-04-20
申请号：US779421
申请日：1997-01-07
Applicant: Stuart D. Edwards , Hugh R. Sharkey , Ingemar H. Lundquist , Ronald G. Lax , James Allen Baker, Jr.
Inventor： Stuart D. Edwards , Hugh R. Sharkey , Ingemar H. Lundquist , Ronald G. Lax , James Allen Baker, Jr.
IPC: A61B18/12 , A61B1/00 , A61B5/01 , A61B10/00 , A61B10/02 , A61B10/06 , A61B17/00 , A61B17/22 , A61B17/24 , A61B17/28 , A61B17/34 , A61B18/00 , A61B18/08 , A61B18/14 , A61B18/18 , A61B18/22 , A61B18/24 , A61B19/00 , A61F7/00 , A61K31/465 , A61M1/00 , A61M3/02 , A61M25/00 , A61M25/14 , A61N1/06 , A61N1/40 , A61N5/02 , A61N5/04 , A61N5/06 , A61B17/39
CPC classification number: A61B10/0233 , A61B10/0275 , A61B10/06 , A61B18/00 , A61B18/1477 , A61B18/1485 , A61B18/18 , A61B18/1815 , A61K31/465 , A61N1/06 , A61N1/40 , A61N1/403 , A61N5/02 , A61N5/045 , A61B1/00188 , A61B10/02 , A61B10/0241 , A61B18/14 , A61B18/1442 , A61B18/148 , A61B18/24 , A61B2017/00084 , A61B2017/00092 , A61B2017/00106 , A61B2017/00274 , A61B2017/00292 , A61B2017/003 , A61B2017/00867 , A61B2017/22072 , A61B2017/22077 , A61B2017/22082 , A61B2017/248 , A61B2017/2939 , A61B2017/3488 , A61B2018/00005 , A61B2018/00011 , A61B2018/00083 , A61B2018/00095 , A61B2018/00196 , A61B2018/0022 , A61B2018/00547 , A61B2018/00577 , A61B2018/00678 , A61B2018/00702 , A61B2018/00726 , A61B2018/00744 , A61B2018/0075 , A61B2018/00761 , A61B2018/00791 , A61B2018/00797 , A61B2018/00821 , A61B2018/00869 , A61B2018/00886 , A61B2018/0091 , A61B2018/00916 , A61B2018/00946 , A61B2018/00982 , A61B2018/1253 , A61B2018/126 , A61B2018/1273 , A61B2018/128 , A61B2018/1425 , A61B2018/2238 , A61B2090/0814 , A61B2090/3614 , A61B2090/3782 , A61B2090/3925 , A61B2217/005 , A61B2217/007 , A61M2025/0086 , A61M2025/0087 , A61M2025/0089 , A61M2025/009 , A61M2025/0096 , A61M2025/018 , A61M25/0032 , A61M25/0045 , A61M25/008 , A61M3/0279 , A61N5/04
Abstract: A medical probe device of this invention comprising a catheter having a control end and a probe end. The probe end includes a stylet guide housing having at least one stylet port and stylet guide means for directing a flexible stylet outward through at least one stylet port and through intervening tissue to targeted tissues. A stylet is positioned in at least one of said stylet guide means, the stylet comprising a non-conductive sleeve having a RF electrode lumen and an optional a fluid supply lumen and a temperature sensor lumen therein. At least one portion of an opposed surface of the electrode lumen and the electrode can be spaced apart to define a liquid supply passageway for delivery of medicament liquid. The RF electrode enclosed within the non-conductive sleeve has a distal length optionally having at least one current focusing groove means thereon and a distal tip shaped to focus current crowding on its terminal end, whereby Rf current passing therefrom into surrounding tissue forms a lesion extending outward from the groove and tip. The focusing groove means can be a plurality of annular focusing grooves or a spiral focusing groove thereon.
Abstract translation: 本发明的医疗探针装置包括具有控制端和探针端的导管。 探针端部包括具有至少一个探针端口和探针引导装置的探针引导壳体，用于将柔性探针向外引导通过至少一个通管孔，并通过介入组织引导到靶组织。 探针定位在所述探针引导装置中的至少一个上，所述探针包括具有RF电极腔和可选的流体供应管腔和其中的温度传感器腔的非导电套管。 电极腔和电极的相对表面的至少一部分可以间隔开以限定用于输送药液的液体供应通道。 封闭在非导电套筒内的RF电极具有任选地在其上具有至少一个电流聚焦槽装置的远端长度，以及形成为将电流拥挤聚焦在其末端上的远端，其中从其进入周围组织的Rf电流形成延伸的病变 从凹槽和尖端向外。 聚焦槽装置可以是多个环形聚焦槽或其上的螺旋形聚焦槽。
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公开(公告)号：US5848986A
公开(公告)日：1998-12-15
申请号：US667452
申请日：1996-06-21
Applicant: Ingemar H. Lundquist , Stuart D. Edwards
Inventor： Ingemar H. Lundquist , Stuart D. Edwards
IPC: A61B10/00 , A61B10/02 , A61B10/06 , A61B17/00 , A61B17/22 , A61B17/24 , A61B17/28 , A61B17/34 , A61B18/00 , A61B18/08 , A61B18/14 , A61B18/18 , A61B18/22 , A61B18/24 , A61B19/00 , A61F7/00 , A61M1/00 , A61M3/02 , A61M25/00 , A61M25/01 , A61M25/092 , A61N1/06 , A61N1/40 , A61N5/04 , A61B17/20
CPC classification number: A61B10/0233 , A61B10/0275 , A61B10/06 , A61B17/3403 , A61B17/3417 , A61B17/3478 , A61B18/00 , A61B18/1477 , A61B18/1485 , A61B18/18 , A61B18/1815 , A61M25/0136 , A61M25/0138 , A61M25/0147 , A61N1/06 , A61N1/40 , A61N1/403 , A61N5/045 , A61B10/02 , A61B10/0241 , A61B18/14 , A61B18/1442 , A61B18/148 , A61B18/1492 , A61B18/24 , A61B2017/00084 , A61B2017/00092 , A61B2017/00101 , A61B2017/00106 , A61B2017/00123 , A61B2017/00181 , A61B2017/00194 , A61B2017/00274 , A61B2017/00292 , A61B2017/003 , A61B2017/00469 , A61B2017/00867 , A61B2017/22072 , A61B2017/22077 , A61B2017/22082 , A61B2017/248 , A61B2017/2939 , A61B2017/3488 , A61B2018/00005 , A61B2018/00011 , A61B2018/00083 , A61B2018/00095 , A61B2018/00101 , A61B2018/00196 , A61B2018/0022 , A61B2018/00547 , A61B2018/00577 , A61B2018/00678 , A61B2018/00702 , A61B2018/00726 , A61B2018/00744 , A61B2018/00761 , A61B2018/00791 , A61B2018/00797 , A61B2018/00821 , A61B2018/00886 , A61B2018/0091 , A61B2018/00916 , A61B2018/00946 , A61B2018/00982 , A61B2018/1253 , A61B2018/126 , A61B2018/1273 , A61B2018/128 , A61B2018/1425 , A61B2018/2238 , A61B2090/0814 , A61B2090/3614 , A61B2090/378 , A61B2090/3782 , A61B2090/3786 , A61B2090/3925 , A61B2217/005 , A61M2025/0086 , A61M2025/0087 , A61M2025/0089 , A61M2025/0096 , A61M2025/018 , A61M25/0068 , A61M25/008 , A61M25/0082 , A61M3/0279 , A61N5/04
Abstract: A medical probe for the treatment by radio frequency ablation of a target volume in tissue of a human having a urethral channel extending into a base of a bladder along a longitudinal axis. The probe comprises an elongate probe member having proximal and distal extremities and sized so that it can be introduced into the urethra. The elongate probe member has a passage extending from the proximal extremity to the distal extremity. Guide cannulae are mounted in the passage of the elongate probe member and have proximal and distal extremities with the distal extremities of the guide cannulae being in the vicinity of the distal extremity of the elongate probe member. Each of the guide cannulae has a lumen extending therethrough from the proximal extremity to the distal extremity. A radio frequency conductive electrode is disposed in each lumen. A control handle is secured to the proximal extremity of the elongate probe member. The control handle is connected to each radio frequency electrode whereby each radio frequency electrode can be advanced and retracted.
Abstract translation: 一种用于通过射线消融处理的医疗探针，其具有沿着纵向轴线延伸到膀胱的基部中的具有尿道的人的组织中的靶体积。 探针包括具有近端和远端的细长探针部件，并且其尺寸使其能够被引入到尿道中。 细长的探针构件具有从近端延伸到远端的通道。 引导套管安装在细长探针构件的通道中，并且具有近端和远端，引导套管的远端在细长探针构件的远端附近。 每个引导套管具有从近端到远端延伸穿过的内腔。 射频导电电极设置在每个管腔中。 控制手柄固定到细长探针构件的近端。 控制手柄连接到每个射频电极，由此每个射频电极可以前进和后退。
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公开(公告)号：US5685839A
公开(公告)日：1997-11-11
申请号：US439191
申请日：1995-05-11
Applicant: Stuart D. Edwards , Ronald G. Lax , Ingemar H. Lundquist , Hugh R. Sharkey , James A. Baker
Inventor： Stuart D. Edwards , Ronald G. Lax , Ingemar H. Lundquist , Hugh R. Sharkey , James A. Baker
IPC: A61B10/00 , A61B10/02 , A61B10/06 , A61B17/00 , A61B17/22 , A61B17/24 , A61B17/28 , A61B17/34 , A61B18/00 , A61B18/08 , A61B18/14 , A61B18/18 , A61B18/22 , A61B18/24 , A61B19/00 , A61F7/00 , A61M1/00 , A61M3/02 , A61M25/00 , A61N1/06 , A61N1/40 , A61N5/02 , A61N5/04
CPC classification number: A61B10/0233 , A61B10/0275 , A61B10/06 , A61B18/00 , A61B18/1477 , A61B18/1482 , A61B18/1485 , A61B18/18 , A61B18/1815 , A61B18/24 , A61N1/06 , A61N1/40 , A61N1/403 , A61N5/02 , A61N5/045 , A61B10/0241 , A61B18/082 , A61B18/1206 , A61B18/14 , A61B18/1402 , A61B18/1442 , A61B18/148 , A61B2017/00084 , A61B2017/00092 , A61B2017/00101 , A61B2017/00106 , A61B2017/00123 , A61B2017/00181 , A61B2017/00194 , A61B2017/00274 , A61B2017/00292 , A61B2017/003 , A61B2017/00867 , A61B2017/22038 , A61B2017/22072 , A61B2017/22077 , A61B2017/22082 , A61B2017/248 , A61B2017/2939 , A61B2017/3488 , A61B2018/00005 , A61B2018/00011 , A61B2018/00041 , A61B2018/00083 , A61B2018/00095 , A61B2018/00101 , A61B2018/00196 , A61B2018/0022 , A61B2018/00547 , A61B2018/00577 , A61B2018/00678 , A61B2018/00702 , A61B2018/00726 , A61B2018/00744 , A61B2018/00761 , A61B2018/00791 , A61B2018/00797 , A61B2018/00821 , A61B2018/00886 , A61B2018/0091 , A61B2018/00916 , A61B2018/00946 , A61B2018/0097 , A61B2018/00982 , A61B2018/1253 , A61B2018/126 , A61B2018/1273 , A61B2018/128 , A61B2018/1425 , A61B2018/1861 , A61B2018/2238 , A61B2090/0814 , A61B2090/3614 , A61B2090/378 , A61B2090/3782 , A61B2090/3786 , A61B2090/3925 , A61B2217/005 , A61B2217/007 , A61F2007/0054 , A61M2025/0086 , A61M2025/0087 , A61M2025/0089 , A61M2025/0096 , A61M2025/018 , A61M25/0068 , A61M3/0279 , A61N5/04
Abstract: A medical probe apparatus comprising a catheter having a stylet guide housing with one or more stylet ports therein and stylet guides for directing one or more flexible stylets outward through respective stylet ports and through intervening tissue to target tissue. The active stylets emit radio frequency RF energy which establishes an RF current in the patient. The current, being densest at the stylet tips, causes heating of the surrounding tissue to initiate ablation of the target tissue. One aspect of the invention includes temperature sensing stylets at the location of the RF emitting stylets to monitor the temperature of the tissue being ablated. This allows the surgeon to have increased knowledge about the abating action under way in order to control the intensity of the applied RF current, or to adjust the amount of time the current is applied, or both. Further included herein is a plurality of temperature sensors mounted on an ultrasound probe to be used to monitor tissue temperature at the ultrasound probe while allowing the ultrasound device to monitor the position and orientation of the medical probe apparatus of the present invention.
Abstract translation: 一种医疗探针装置，包括具有其中具有一个或多个管心针孔的探针引导壳体的导管，以及用于通过相应的针尖端口向外引导一个或多个柔性护套的探针引导件，以及通过介入组织到靶组织。 主动式发射射频RF能量，其在患者体内建立RF电流。 在探针尖端处最密集的电流导致周围组织的加热以引发靶组织的消融。 本发明的一个方面包括在RF发射样式的位置处的温度感测样式，以监测被消融的组织的温度。 这允许外科医生增加关于正在进行的减轻动作的知识，以便控制施加的RF电流的强度，或者调整施加电流的时间量，或者两者。 此外还包括安装在超声波探头上的多个温度传感器，用于监测超声波探头的组织温度，同时允许超声波装置监测本发明的医疗探针装置的位置和取向。
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公开(公告)号：US5582589A
公开(公告)日：1996-12-10
申请号：US465718
申请日：1995-06-06
Applicant: Stuart D. Edwards , Hugh R. Sharkey , Ingemar H. Lundquist , Ronald G. Lax , James A. Baker, Jr.
Inventor： Stuart D. Edwards , Hugh R. Sharkey , Ingemar H. Lundquist , Ronald G. Lax , James A. Baker, Jr.
IPC: A61B18/12 , A61B1/00 , A61B5/01 , A61B10/00 , A61B10/02 , A61B10/06 , A61B17/00 , A61B17/22 , A61B17/24 , A61B17/28 , A61B17/34 , A61B18/00 , A61B18/08 , A61B18/14 , A61B18/18 , A61B18/22 , A61B18/24 , A61B19/00 , A61F7/00 , A61K31/465 , A61M1/00 , A61M3/02 , A61M25/00 , A61M25/14 , A61N1/06 , A61N1/40 , A61N5/02 , A61N5/04 , A61N5/06 , A61B17/39
CPC classification number: A61B10/0233 , A61B10/0275 , A61B10/06 , A61B18/00 , A61B18/1477 , A61B18/1485 , A61B18/18 , A61B18/1815 , A61K31/465 , A61N1/06 , A61N1/40 , A61N1/403 , A61N5/02 , A61N5/045 , A61B1/00188 , A61B10/02 , A61B10/0241 , A61B18/14 , A61B18/1442 , A61B18/148 , A61B18/24 , A61B2017/00084 , A61B2017/00092 , A61B2017/00106 , A61B2017/00274 , A61B2017/00292 , A61B2017/003 , A61B2017/00867 , A61B2017/22072 , A61B2017/22077 , A61B2017/22082 , A61B2017/248 , A61B2017/2939 , A61B2017/3488 , A61B2018/00005 , A61B2018/00011 , A61B2018/00083 , A61B2018/00095 , A61B2018/00196 , A61B2018/0022 , A61B2018/00547 , A61B2018/00577 , A61B2018/00678 , A61B2018/00702 , A61B2018/00726 , A61B2018/00744 , A61B2018/0075 , A61B2018/00761 , A61B2018/00791 , A61B2018/00797 , A61B2018/00821 , A61B2018/00869 , A61B2018/00886 , A61B2018/0091 , A61B2018/00916 , A61B2018/00946 , A61B2018/00982 , A61B2018/1253 , A61B2018/126 , A61B2018/1273 , A61B2018/128 , A61B2018/1425 , A61B2018/2238 , A61B2090/0814 , A61B2090/3614 , A61B2090/3782 , A61B2090/3925 , A61B2217/005 , A61B2217/007 , A61M2025/0086 , A61M2025/0087 , A61M2025/0089 , A61M2025/009 , A61M2025/0096 , A61M2025/018 , A61M25/0032 , A61M25/0045 , A61M25/008 , A61M3/0279 , A61N5/04
Abstract: A medical probe device of this invention comprising a catheter having a control end and a probe end. The probe end includes a stylet guide housing having at least one stylet port and stylet guide means for directing a flexible stylet outward through at least one stylet port and through intervening tissue to targeted tissues. A stylet is positioned in at least one of said stylet guide means, the stylet comprising a non-conductive sleeve having a RF electrode lumen and an optional a fluid supply lumen and a temperature sensor lumen therein. At least one portion of an opposed surface of the electrode lumen and the electrode can be spaced apart to define a liquid supply passageway for delivery of medicament liquid. The RF electrode enclosed within the non-conductive sleeve has a distal length optionally having at least one current focusing groove means thereon and a distal tip shaped to focus current crowding on its terminal end, whereby Rf current passing therefrom into surrounding tissue forms a lesion extending outward from the groove and tip. The focusing groove means can be a plurality of annular focusing grooves or a spiral focusing groove thereon.
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公开(公告)号：US5554110A
公开(公告)日：1996-09-10
申请号：US180578
申请日：1994-01-12
Applicant: Stuart D. Edwards , Ronald G. Lax , Ingemar H. Lundquist , Hugh R. Sharkey , James A. Baker
Inventor： Stuart D. Edwards , Ronald G. Lax , Ingemar H. Lundquist , Hugh R. Sharkey , James A. Baker
IPC: A61B18/12 , A61B1/00 , A61B5/01 , A61B10/00 , A61B10/02 , A61B10/06 , A61B17/00 , A61B17/22 , A61B17/24 , A61B17/28 , A61B17/34 , A61B18/00 , A61B18/08 , A61B18/14 , A61B18/18 , A61B18/22 , A61B18/24 , A61B19/00 , A61F7/00 , A61K31/465 , A61M1/00 , A61M3/02 , A61M25/00 , A61M25/14 , A61N1/06 , A61N1/40 , A61N5/02 , A61N5/04 , A61N5/06 , A61B17/39
CPC classification number: A61B10/0233 , A61B10/0275 , A61B10/06 , A61B18/00 , A61B18/1477 , A61B18/1485 , A61B18/18 , A61B18/1815 , A61K31/465 , A61N1/06 , A61N1/40 , A61N1/403 , A61N5/02 , A61N5/045 , A61B1/00188 , A61B10/02 , A61B10/0241 , A61B18/14 , A61B18/1442 , A61B18/148 , A61B18/24 , A61B2017/00084 , A61B2017/00092 , A61B2017/00106 , A61B2017/00274 , A61B2017/00292 , A61B2017/003 , A61B2017/00867 , A61B2017/22072 , A61B2017/22077 , A61B2017/22082 , A61B2017/248 , A61B2017/2939 , A61B2017/3488 , A61B2018/00005 , A61B2018/00011 , A61B2018/00083 , A61B2018/00095 , A61B2018/00196 , A61B2018/0022 , A61B2018/00547 , A61B2018/00577 , A61B2018/00678 , A61B2018/00702 , A61B2018/00726 , A61B2018/00744 , A61B2018/0075 , A61B2018/00761 , A61B2018/00791 , A61B2018/00797 , A61B2018/00821 , A61B2018/00869 , A61B2018/00886 , A61B2018/0091 , A61B2018/00916 , A61B2018/00946 , A61B2018/00982 , A61B2018/1253 , A61B2018/126 , A61B2018/1273 , A61B2018/128 , A61B2018/1425 , A61B2018/2238 , A61B2090/0814 , A61B2090/3614 , A61B2090/3782 , A61B2090/3925 , A61B2217/005 , A61B2217/007 , A61M2025/0086 , A61M2025/0087 , A61M2025/0089 , A61M2025/009 , A61M2025/0096 , A61M2025/018 , A61M25/0032 , A61M25/0045 , A61M25/008 , A61M3/0279 , A61N5/04
Abstract: A medical probe device including a catheter having a stylet guide housing with one or more stylet ports in a side wall thereof and a for directing a flexible stylet outward through the stylet port and through intervening tissue at a preselected, adjustable angle to a target tissue. The total catheter assembly includes a stylet guide lumen communicating with the stylet port and a stylet positioned in said stylet guide lumen for longitudinal movement from the port through intervening tissue to a target tissue. The stylet can be an electrical conductor enclosed within a non-conductive layer, the electrical conductor being a radio frequency electrode. During the ablation operation, the tissue immediately adjacent the stylet can become desiccated, thereby necessitating an increase of current flow and a loss of ablation efficiency. A forward and reverse movement of the non-conductive sleeve on the stylet during an operation frees the stylet from sticking tissue and creates a space around the electrode to allow the tissue to rehydrate.
Abstract translation: 一种医疗探针装置，其包括导管，该导管具有在其侧壁中具有一个或多个管心针端口的探针引导壳体，以及用于将柔性探针向外引导通过探针端口，并通过介入组织以与靶组织预选的可调节角度。 总导管组件包括与通管孔端口连通的探针引导腔和位于所述探针引导腔中的探针，用于从端口到介入组织到目标组织的纵向移动。 探针可以是封装在非导电层内的电导体，电导体是射频电极。 在消融操作期间，紧邻探针针的组织可能变干，从而需要电流增加和消融效率的降低。 在操作期间非导电套管在探针上的向前和反向运动使探针从粘附组织释放，并在电极周围产生空间以允许组织再水合。
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Patent Agency Ranking
公开(公告)号：US5542915A
公开(公告)日：1996-08-06
申请号：US180511
申请日：1994-01-12
Applicant: Stuart D. Edwards , Ronald G. Lax , Ingemar H. Lundquist , Hugh R. Sharkey , James A. Baker
Inventor： Stuart D. Edwards , Ronald G. Lax , Ingemar H. Lundquist , Hugh R. Sharkey , James A. Baker
IPC: A61B10/00 , A61B10/02 , A61B10/06 , A61B17/00 , A61B17/22 , A61B17/24 , A61B17/28 , A61B17/34 , A61B18/00 , A61B18/08 , A61B18/14 , A61B18/18 , A61B18/22 , A61B18/24 , A61B19/00 , A61F7/00 , A61M1/00 , A61M3/02 , A61M25/00 , A61N1/06 , A61N1/40 , A61N5/02 , A61N5/04 , A61B17/39
CPC classification number: A61B10/0233 , A61B10/0275 , A61B10/06 , A61B18/00 , A61B18/1477 , A61B18/1482 , A61B18/1485 , A61B18/18 , A61B18/1815 , A61B18/24 , A61N1/06 , A61N1/40 , A61N1/403 , A61N5/02 , A61N5/045 , A61B10/0241 , A61B18/082 , A61B18/1206 , A61B18/14 , A61B18/1402 , A61B18/1442 , A61B18/148 , A61B2017/00084 , A61B2017/00092 , A61B2017/00101 , A61B2017/00106 , A61B2017/00123 , A61B2017/00181 , A61B2017/00194 , A61B2017/00274 , A61B2017/00292 , A61B2017/003 , A61B2017/00867 , A61B2017/22038 , A61B2017/22072 , A61B2017/22077 , A61B2017/22082 , A61B2017/248 , A61B2017/2939 , A61B2017/3488 , A61B2018/00005 , A61B2018/00011 , A61B2018/00041 , A61B2018/00083 , A61B2018/00095 , A61B2018/00101 , A61B2018/00196 , A61B2018/0022 , A61B2018/00547 , A61B2018/00577 , A61B2018/00678 , A61B2018/00702 , A61B2018/00726 , A61B2018/00744 , A61B2018/00761 , A61B2018/00791 , A61B2018/00797 , A61B2018/00821 , A61B2018/00886 , A61B2018/0091 , A61B2018/00916 , A61B2018/00946 , A61B2018/0097 , A61B2018/00982 , A61B2018/1253 , A61B2018/126 , A61B2018/1273 , A61B2018/128 , A61B2018/1425 , A61B2018/1861 , A61B2018/2238 , A61B2090/0814 , A61B2090/3614 , A61B2090/378 , A61B2090/3782 , A61B2090/3786 , A61B2090/3925 , A61B2217/005 , A61B2217/007 , A61F2007/0054 , A61M2025/0086 , A61M2025/0087 , A61M2025/0089 , A61M2025/0096 , A61M2025/018 , A61M25/0068 , A61M3/0279 , A61N5/04
Abstract: A medical probe apparatus comprising a catheter having a stylet guide housing with one or more stylet ports therein and stylet guides for directing one or more flexible stylets outward through respective stylet ports and through intervening tissue to target tissue. The active stylets emit radio frequency RF energy which establishes an RF current in the patient. The current, being densest at the stylet tips, causes heating of the surrounding tissue to initiate ablation of the target tissue. One aspect of the invention includes temperature sensing stylets at the location of the RF emitting stylets to monitor the temperature of the tissue being ablated. This allows the surgeon to have increased knowledge about the abating action under way in order to control the intensity of the applied RF current, or to adjust the amount of time the current is applied, or both. Further included herein is a plurality of temperature sensors mounted on an ultrasound probe to be used to monitor tissue temperature at the ultrasound probe while allowing the ultrasound device to monitor the position and orientation of the medical probe apparatus of the present invention.
Abstract translation: 一种医疗探针装置，包括具有其中具有一个或多个管心针孔的探针引导壳体的导管，以及用于通过相应的针尖端口向外引导一个或多个柔性护套的探针引导件，以及通过介入组织到靶组织。 主动式发射射频RF能量，其在患者体内建立RF电流。 在探针尖端处最密集的电流导致周围组织的加热以引发靶组织的消融。 本发明的一个方面包括在RF发射样式的位置处的温度感测样式，以监测被消融的组织的温度。 这允许外科医生增加关于正在进行的减轻动作的知识，以便控制施加的RF电流的强度，或者调整施加电流的时间量，或者两者。 此外还包括安装在超声波探头上的多个温度传感器，用于监测超声波探头的组织温度，同时允许超声波装置监测本发明的医疗探针装置的位置和取向。
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公开(公告)号：US5531677A
公开(公告)日：1996-07-02
申请号：US420304
申请日：1995-04-11
Applicant: Ingemar H. Lundquist , Stuart D. Edwards
Inventor： Ingemar H. Lundquist , Stuart D. Edwards
IPC: A61B10/00 , A61B10/02 , A61B10/06 , A61B17/00 , A61B17/22 , A61B17/24 , A61B17/28 , A61B17/34 , A61B18/00 , A61B18/08 , A61B18/14 , A61B18/18 , A61B18/22 , A61B18/24 , A61B19/00 , A61F7/00 , A61M1/00 , A61M3/02 , A61M25/00 , A61M25/01 , A61M25/092 , A61N1/06 , A61N1/40 , A61N5/04 , A61B17/20
CPC classification number: A61B10/0233 , A61B10/0275 , A61B10/06 , A61B17/3403 , A61B17/3417 , A61B17/3478 , A61B18/00 , A61B18/1477 , A61B18/1485 , A61B18/18 , A61B18/1815 , A61M25/0136 , A61M25/0138 , A61M25/0147 , A61N1/06 , A61N1/40 , A61N1/403 , A61N5/045 , A61B10/02 , A61B10/0241 , A61B18/14 , A61B18/1442 , A61B18/148 , A61B18/1492 , A61B18/24 , A61B2017/00084 , A61B2017/00092 , A61B2017/00101 , A61B2017/00106 , A61B2017/00123 , A61B2017/00181 , A61B2017/00194 , A61B2017/00274 , A61B2017/00292 , A61B2017/003 , A61B2017/00469 , A61B2017/00867 , A61B2017/22072 , A61B2017/22077 , A61B2017/22082 , A61B2017/248 , A61B2017/2939 , A61B2017/3488 , A61B2018/00005 , A61B2018/00011 , A61B2018/00083 , A61B2018/00095 , A61B2018/00101 , A61B2018/00196 , A61B2018/0022 , A61B2018/00547 , A61B2018/00577 , A61B2018/00678 , A61B2018/00702 , A61B2018/00726 , A61B2018/00744 , A61B2018/00761 , A61B2018/00791 , A61B2018/00797 , A61B2018/00821 , A61B2018/00886 , A61B2018/0091 , A61B2018/00916 , A61B2018/00946 , A61B2018/00982 , A61B2018/1253 , A61B2018/126 , A61B2018/1273 , A61B2018/128 , A61B2018/1425 , A61B2018/2238 , A61B2090/0814 , A61B2090/3614 , A61B2090/378 , A61B2090/3782 , A61B2090/3786 , A61B2090/3925 , A61B2217/005 , A61M2025/0086 , A61M2025/0087 , A61M2025/0089 , A61M2025/0096 , A61M2025/018 , A61M25/0068 , A61M25/008 , A61M25/0082 , A61M3/0279 , A61N5/04
Abstract: A medical probe for the treatment by radio frequency ablation of a target volume in tissue of a human having a urethral channel extending into the base of a bladder along a longitudinal axis. The probe comprises an elongate probe member having proximal and distal extremities and is sized so that it can be introduced into the urethra. The elongate probe member has a passage extending from the proximal extremity to the distal extremity. Guide cannulae are mounted in the passage of the elongate probe member and have proximal and distal extremities with the distal extremities of the guide cannulae being in the vicinity of the distal extremity of the elongate probe member. Each of the guide cannulae have a lumen extending therethrough from the proximal extremity to the distal extremity. A radio frequency conductive electrode is disposed in each lumen. An insulating sleeve is coaxially disposed on each radio frequency electrode. A control handle is secured to the proximal extremity of the elongate probe member. The control handle is connected to each radio frequency electrode and each insulating sleeve so that each radio frequency electrode and each insulating sleeve can be advanced and retracted.
Abstract translation: 一种用于通过射线消融处理的医疗探针，其具有沿着纵向轴线延伸到膀胱的基部中的具有尿道通道的人的组织中的靶体积。 探针包括具有近端和远端的细长探针部件，其尺寸使其能够被引入尿道。 细长的探针构件具有从近端延伸到远端的通道。 引导套管安装在细长探针构件的通道中，并且具有近端和远端，引导套管的远端在细长探针构件的远端附近。 每个引导套管具有从近端到远端延伸穿过的内腔。 射频导电电极设置在每个管腔中。 绝缘套管同轴地设置在每个射频电极上。 控制手柄固定到细长探针构件的近端。 控制手柄连接到每个射频电极和每个绝缘套管，使得每个射频电极和每个绝缘套管可以前进和后退。
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公开(公告)号：US06814712B1
公开(公告)日：2004-11-09
申请号：US08723588
申请日：1996-10-01
Applicant: Stuart D. Edwards , Ronald G. Lax , Ingemar H. Lundquist , Hugh R. Sharkey
Inventor： Stuart D. Edwards , Ronald G. Lax , Ingemar H. Lundquist , Hugh R. Sharkey
IPC: A61B1720
CPC classification number: A61N5/02 , A61B10/02 , A61B10/0241 , A61B18/00 , A61B18/082 , A61B18/1206 , A61B18/1477 , A61B18/148 , A61B18/1485 , A61B18/18 , A61B18/1815 , A61B18/24 , A61B2017/00084 , A61B2017/00092 , A61B2017/00106 , A61B2017/00274 , A61B2017/00292 , A61B2017/003 , A61B2017/00867 , A61B2017/22072 , A61B2017/22077 , A61B2017/22082 , A61B2017/248 , A61B2017/2939 , A61B2017/3488 , A61B2018/00005 , A61B2018/00011 , A61B2018/00083 , A61B2018/00095 , A61B2018/00196 , A61B2018/0022 , A61B2018/00547 , A61B2018/00577 , A61B2018/00678 , A61B2018/00702 , A61B2018/00726 , A61B2018/00744 , A61B2018/0075 , A61B2018/00761 , A61B2018/00791 , A61B2018/00797 , A61B2018/00821 , A61B2018/00869 , A61B2018/00886 , A61B2018/0091 , A61B2018/00916 , A61B2018/00946 , A61B2018/00982 , A61B2018/1253 , A61B2018/126 , A61B2018/1273 , A61B2018/128 , A61B2018/1412 , A61B2018/1425 , A61B2018/1861 , A61B2018/2238 , A61B2090/0814 , A61B2090/3614 , A61B2090/3782 , A61B2090/3925 , A61F2007/0054 , A61M3/0279 , A61M25/0068 , A61M25/0069 , A61M25/008 , A61M25/0082 , A61M2025/0086 , A61M2025/0087 , A61M2025/0089 , A61M2025/009 , A61M2025/0096 , A61M2025/018 , A61N1/06 , A61N1/40 , A61N1/403 , A61N5/04 , A61N5/045
Abstract: A medical probe device comprises a catheter having a stylet guide housing with one or more stylet ports in a side wall thereof and a stylet guide for directing a flexible stylet outward through the stylet port and through intervening tissue at a preselected, adjustable angle to a target tissue. The total catheter assembly includes a stylet guide lumen communicating with the stylet port and a stylet positioned in said stylet guide lumen for longitudinal movement from the port through intervening tissue to a target tissue. The stylet can be an electrical conductor enclosed within a non-conductive layer, the electrical conductor being a radiofrequency electrode. Preferably, the non-conductive layer is a sleeve which is axially moveable on the electrical conductor to expose a selected portion of the electrical conductor surface in the target tissue. The stylet can also be a microwave antenna. The stylet can also be a hollow tube for delivering treatment fluid to the target tissue. It can also include a fiber optic cable for laser treatment. The catheter can include one or more inflatable balloons located adjacent to the stylet port for anchoring the catheter or dilation. Ultrasound transponders and temperature sensors can be attached to the probe end and/or stylet. The stylet guide can define a stylet path from an axial orientation in the catheter through a curved portion to a lateral orientation at the stylet port.
Abstract translation: 医疗探针装置包括导管，其具有在其侧壁中具有一个或多个管心针端口的探针引导壳体和用于将柔性探针向外引导通过探针端口的探针引导件，并且以与预定的可调节角度相对的目标通过介入组织 组织。 总导管组件包括与通管孔端口连通的探针引导腔和位于所述探针引导腔中的探针，用于从端口到介入组织到目标组织的纵向移动。 探针可以是封闭在非导电层内的电导体，电导体是射频电极。 优选地，非导电层是可在电导体上轴向移动以暴露目标组织中电导体表面的选定部分的套筒。 探针也可以是微波天线。 探针也可以是用于将治疗流体输送到靶组织的中空管。 它还可以包括用于激光治疗的光纤电缆。 导管可以包括一个或多个位于探针端口附近的可充气气囊，用于锚定导管或扩张。 超声波转发器和温度传感器可以连接到探针端和/或探针。 探针引导件可以从导管中的轴向方向定义探针路径，通过弯曲部分到管心针端口处的横向取向。
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公开(公告)号：US06464661B2
公开(公告)日：2002-10-15
申请号：US09819151
申请日：2001-03-27
Applicant: Stuart D. Edwards , Hugh R. Sharkey , Ingemar H. Lundquist , Ronald G. Lax , James Allen Baker, Jr.
Inventor： Stuart D. Edwards , Hugh R. Sharkey , Ingemar H. Lundquist , Ronald G. Lax , James Allen Baker, Jr.
IPC: A61B1720
CPC classification number: A61B10/0233 , A61B1/00188 , A61B10/02 , A61B10/0241 , A61B10/0275 , A61B10/06 , A61B18/00 , A61B18/14 , A61B18/1477 , A61B18/148 , A61B18/1485 , A61B18/18 , A61B18/1815 , A61B18/24 , A61B2017/00084 , A61B2017/00092 , A61B2017/00106 , A61B2017/00274 , A61B2017/00292 , A61B2017/003 , A61B2017/00867 , A61B2017/22072 , A61B2017/22077 , A61B2017/22082 , A61B2017/248 , A61B2017/2939 , A61B2017/3488 , A61B2018/00005 , A61B2018/00011 , A61B2018/00083 , A61B2018/00095 , A61B2018/00196 , A61B2018/0022 , A61B2018/00547 , A61B2018/00577 , A61B2018/00678 , A61B2018/00702 , A61B2018/00726 , A61B2018/00744 , A61B2018/0075 , A61B2018/00761 , A61B2018/00791 , A61B2018/00797 , A61B2018/00821 , A61B2018/00869 , A61B2018/00886 , A61B2018/0091 , A61B2018/00916 , A61B2018/00946 , A61B2018/00982 , A61B2018/1253 , A61B2018/126 , A61B2018/1273 , A61B2018/128 , A61B2018/1425 , A61B2018/2238 , A61B2090/0814 , A61B2090/3614 , A61B2090/3782 , A61B2090/3925 , A61B2217/005 , A61B2217/007 , A61K31/465 , A61M3/0279 , A61M25/0032 , A61M25/0045 , A61M25/008 , A61M2025/0086 , A61M2025/0087 , A61M2025/0089 , A61M2025/009 , A61M2025/0096 , A61M2025/018 , A61N1/06 , A61N1/40 , A61N1/403 , A61N5/02 , A61N5/04 , A61N5/045
Abstract: A medical probe device of this invention comprising a catheter having a control end and a probe end. The probe end includes a stylet guide housing having at least one stylet port and stylet guide means for directing a flexible stylet outward through at least one stylet port and through intervening tissue to targeted tissues. A stylet is positioned in at least one of said stylet guide means, the stylet comprising a non-conductive sleeve having a RF electrode lumen and an optional a fluid supply lumen and a temperature sensor lumen therein. At least one portion of an opposed surface of the electrode lumen and the electrode can be spaced apart to define a liquid supply passageway for delivery of medicament liquid. The RF electrode enclosed within the non-conductive sleeve has a distal length optionally having at least one current focusing groove means thereon and a distal tip shaped to focus current crowding on its terminal end, whereby Rf current passing therefrom into surrounding tissue forms a lesion extending outward from the groove and tip. The focusing groove means can be a plurality of annular focusing grooves or a spiral focusing groove thereon.
Abstract translation: 本发明的医疗探针装置包括具有控制端和探针端的导管。 探针端部包括具有至少一个探针端口和探针引导装置的探针引导壳体，用于将柔性探针向外引导通过至少一个通管孔，并通过介入组织引导到靶组织。 探针定位在所述探针引导装置中的至少一个上，所述探针包括具有RF电极腔和可选的流体供应管腔和其中的温度传感器腔的非导电套管。 电极腔和电极的相对表面的至少一部分可以间隔开以限定用于输送药液的液体供应通道。 封闭在非导电套筒内的RF电极具有任选地在其上具有至少一个电流聚焦槽装置的远端长度，以及形成为将电流拥挤聚焦在其末端上的远端，其中从其进入周围组织的Rf电流形成延伸的病变 从凹槽和尖端向外。 聚焦槽装置可以是多个环形聚焦槽或其上的螺旋形聚焦槽。
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公开(公告)号：US06102886A
公开(公告)日：2000-08-15
申请号：US85313
申请日：1998-05-27
Applicant: Ingemar H. Lundquist , Stuart D. Edwards
Inventor： Ingemar H. Lundquist , Stuart D. Edwards
IPC: A61B10/00 , A61B10/02 , A61B10/06 , A61B17/00 , A61B17/22 , A61B17/24 , A61B17/28 , A61B17/34 , A61B18/00 , A61B18/08 , A61B18/14 , A61B18/18 , A61B18/22 , A61B18/24 , A61B19/00 , A61F7/00 , A61M1/00 , A61M3/02 , A61M25/00 , A61M25/01 , A61M25/092 , A61N1/06 , A61N1/40 , A61N5/04 , A61B17/20
CPC classification number: A61B10/0233 , A61B10/0275 , A61B10/06 , A61B17/3403 , A61B17/3417 , A61B17/3478 , A61B18/00 , A61B18/1477 , A61B18/1485 , A61B18/18 , A61B18/1815 , A61M25/0136 , A61M25/0138 , A61M25/0147 , A61N1/06 , A61N1/40 , A61N1/403 , A61N5/045 , A61B10/02 , A61B10/0241 , A61B18/14 , A61B18/1442 , A61B18/148 , A61B18/1492 , A61B18/24 , A61B2017/00084 , A61B2017/00092 , A61B2017/00101 , A61B2017/00106 , A61B2017/00123 , A61B2017/00181 , A61B2017/00194 , A61B2017/00274 , A61B2017/00292 , A61B2017/003 , A61B2017/00469 , A61B2017/00867 , A61B2017/22072 , A61B2017/22077 , A61B2017/22082 , A61B2017/248 , A61B2017/2939 , A61B2017/3488 , A61B2018/00005 , A61B2018/00011 , A61B2018/00083 , A61B2018/00095 , A61B2018/00101 , A61B2018/00196 , A61B2018/0022 , A61B2018/00547 , A61B2018/00577 , A61B2018/00678 , A61B2018/00702 , A61B2018/00726 , A61B2018/00744 , A61B2018/00761 , A61B2018/00791 , A61B2018/00797 , A61B2018/00821 , A61B2018/00886 , A61B2018/0091 , A61B2018/00916 , A61B2018/00946 , A61B2018/00982 , A61B2018/1253 , A61B2018/126 , A61B2018/1273 , A61B2018/128 , A61B2018/1425 , A61B2018/2238 , A61B2090/0814 , A61B2090/3614 , A61B2090/378 , A61B2090/3782 , A61B2090/3786 , A61B2090/3925 , A61B2217/005 , A61M2025/0086 , A61M2025/0087 , A61M2025/0089 , A61M2025/0096 , A61M2025/018 , A61M25/0068 , A61M25/008 , A61M25/0082 , A61M3/0279 , A61N5/04
Abstract: A medical probe for the treatment by radio frequency ablation of tissue in a human comprising an elongate probe member having proximal and distal extremities. The elongate probe member has a longitudinal axis and at least one passage extending from the proximal extremity to the distal extremity. A guide cannula is mounted in the at least one passage of the elongate probe member and has proximal and distal extremities with the distal extremity of the guide cannula being in the vicinity of the distal extremity of the elongate probe member. The guide cannula has an opening in the distal extremity and a lumen extending from the proximal extremity to the opening in the distal extremity. A stylet is slidably disposed in the lumen of the guide cannula and includes a radio frequency electrode having a distal portion and a layer of insulating material disposed around the radio frequency so that at least the distal portion is exposed. A handle is coupled to the proximal extremity of the elongate probe member. The distal extremity of he guide cannula has a bendable distal portion. The handle includes a first actuator for causing the distal portion of the guide cannula to bend at an angle to the longitudinal axis so that the opening faces the tissue and a second actuator secured to the stylet for advancing the radio frequency electrode and the layer of insulating material from the opening in the guide cannula into the tissue.
Abstract translation: 一种用于通过人体组织射频消融治疗的医用探针，包括具有近端和远端的细长探针部件。 细长的探针构件具有纵向轴线和从近端延伸到远端的至少一个通道。 引导套管安装在细长探针构件的至少一个通道中并且具有近端和远端四肢，导管的远端末端处于细长探针构件的远端附近。 导向套管在远侧末端具有开口，以及从近端延伸到远端末端的开口的内腔。 探针可滑动地设置在导管的内腔中，并且包括射频电极，其具有围绕射频设置的远侧部分和绝缘材料层，使得至少远端部分暴露。 手柄联接到细长探针构件的近端。 导向套管的远端具有可弯曲的远端部分。 手柄包括第一致动器，用于使引导套管的远端部分与纵向轴线成一定角度弯曲，使得开口面向组织，并且固定到探针的第二致动器用于推进射频电极和绝缘层 材料从引导套管中的开口进入组织。
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