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公开(公告)号：US11654411B2
公开(公告)日：2023-05-23
申请号：US17205263
申请日：2021-03-18
发明人： Mark Edward Brennan Smith , Andrea Sabot , Isabelle Marie Julia Rasolonjatovo , Jean-Ernest Sohna Sohna , Adrian Martin Horgan , Harold Philip Swerdlow
IPC分类号： B01J19/00 , C40B50/18 , C12Q1/6834 , C40B40/06 , C12Q1/6876 , C12Q1/6806 , C12Q1/6837 , C08F222/38
CPC分类号： B01J19/0046 , C08F222/38 , C12Q1/6806 , C12Q1/6834 , C12Q1/6837 , C12Q1/6876 , C40B40/06 , C40B50/18 , B01J2219/0061 , B01J2219/0072 , B01J2219/00351 , B01J2219/00527 , B01J2219/00529 , B01J2219/00585 , B01J2219/00596 , B01J2219/00605 , B01J2219/00608 , B01J2219/00612 , B01J2219/00617 , B01J2219/00626 , B01J2219/00637 , B01J2219/00639 , B01J2219/00641 , B01J2219/00716 , B01J2219/00722 , Y10T428/265
摘要： Methods and compositions are disclosed relating to the localization of nucleic acids to arrays such as silane-free arrays, and of sequencing the nucleic acids localized thereby.
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公开(公告)号：US20220016592A1
公开(公告)日：2022-01-20
申请号：US17205263
申请日：2021-03-18
发明人： Mark Edward Brennan Smith , Andrea Sabot , Isabelle Marie Julia Rasolonjatovo , Jean-Ernest Sohna Sohna , Adrian Martin Horgan , Harold Philip Swerdlow
IPC分类号： B01J19/00 , C40B50/18 , C12Q1/6834 , C40B40/06 , C12Q1/6876 , C12Q1/6806 , C12Q1/6837 , C08F222/38
摘要： Methods and compositions are disclosed relating to the localization of nucleic acids to arrays such as silane-free arrays, and of sequencing the nucleic acids localized thereby.
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公开(公告)号：US20160256846A1
公开(公告)日：2016-09-08
申请号：US15162304
申请日：2016-05-23
发明人： Mark Edward Brennan Smith , Andrea Sabot , Isabelle Marie Julia Rasolonjatovo , Jean-Ernest Sohna Sohna , Adrian Martin Horgan , Harold Philip Swerdlow
IPC分类号： B01J19/00 , C08F222/38 , C12Q1/68
CPC分类号： B01J19/0046 , B01J2219/00351 , B01J2219/00527 , B01J2219/00529 , B01J2219/00585 , B01J2219/00596 , B01J2219/00605 , B01J2219/00608 , B01J2219/0061 , B01J2219/00612 , B01J2219/00617 , B01J2219/00626 , B01J2219/00637 , B01J2219/00639 , B01J2219/00641 , B01J2219/00716 , B01J2219/0072 , B01J2219/00722 , C08F222/38 , C12Q1/6806 , C12Q1/6834 , C12Q1/6837 , C12Q1/6876 , C40B40/06 , C40B50/18 , Y10T428/265
摘要： Methods and compositions are disclosed relating to the localization of nucleic acids to arrays such as silane-free arrays, and of sequencing the nucleic acids localized thereby.
摘要翻译： 公开了关于将核酸定位到诸如无硅烷基阵列的阵列的方法和组合物，以及对其定位的核酸进行测序。
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公开(公告)号：US20230012469A9
公开(公告)日：2023-01-12
申请号：US17005662
申请日：2020-08-28
IPC分类号： C12Q1/6869
摘要： The invention relates to methods for pairwise sequencing of a polynucleotide template which result in the sequential determination of nucleotide sequence in two distinct and separate regions of the polynucleotide template.
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公开(公告)号：US10953379B2
公开(公告)日：2021-03-23
申请号：US16707527
申请日：2019-12-09
发明人： Mark Edward Brennan Smith , Andrea Sabot , Isabelle Marie Julia Rasolonjatovo , Jean-Ernest Sohna Sohna , Adrian Martin Horgan , Harold Philip Swerdlow
IPC分类号： C12Q1/6876 , C12Q1/6806 , B01J19/00 , C40B50/18 , C12Q1/6834 , C40B40/06 , C12Q1/6837 , C08F222/38
摘要： Methods and compositions are disclosed relating to the localization of nucleic acids to arrays such as silane-free arrays, and of sequencing the nucleic acids localized thereby.
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公开(公告)号：US11542553B2
公开(公告)日：2023-01-03
申请号：US17005662
申请日：2020-08-28
IPC分类号： C12P19/34 , C12Q1/6869 , C12Q1/6853
摘要： The invention relates to methods for pairwise sequencing of a polynucleotide template which result in the sequential determination of nucleotide sequence in two distinct and separate regions of the polynucleotide template.
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公开(公告)号：US10525437B2
公开(公告)日：2020-01-07
申请号：US15864384
申请日：2018-01-08
发明人： Mark Edward Brennan Smith , Andrea Sabot , Isabelle Marie Julia Rasolonjatovo , Jean-Ernest Sohna Sohna , Adrian Martin Horgan , Harold Philip Swerdlow
IPC分类号： C40B40/06 , C12Q1/6876 , B01J19/00 , C40B50/18 , C12Q1/6806 , C12Q1/6837 , C08F222/38 , C12Q1/6834
摘要： Methods and compositions are disclosed relating to the localization of nucleic acids to arrays such as silane-free arrays, and of sequencing the nucleic acids localized thereby.
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公开(公告)号：US20170342482A1
公开(公告)日：2017-11-30
申请号：US15677788
申请日：2017-08-15
IPC分类号： C12Q1/68
CPC分类号： C12Q1/6869 , C12Q1/6853 , C12Q2565/525 , C12Q2533/101 , C12Q2525/119 , C12Q2525/301 , C12Q2535/119 , C12Q2565/537
摘要： The invention relates to methods for pairwise sequencing of a polynucleotide template which result in the sequential determination of nucleotide sequence in two distinct and separate regions of the polynucleotide template.
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公开(公告)号：US20150119295A1
公开(公告)日：2015-04-30
申请号：US14592766
申请日：2015-01-08
发明人： Mark Edward Brennan Smith , Andrea Sabot , Isabelle Marie Julia Rasolonjatovo , Jean-Ernest Sohna Sohna , Adrian Martin Horgan , Harold Philip Swerdlow
IPC分类号： C12Q1/68
CPC分类号： B01J19/0046 , B01J2219/00351 , B01J2219/00527 , B01J2219/00529 , B01J2219/00585 , B01J2219/00596 , B01J2219/00605 , B01J2219/00608 , B01J2219/0061 , B01J2219/00612 , B01J2219/00617 , B01J2219/00626 , B01J2219/00637 , B01J2219/00639 , B01J2219/00641 , B01J2219/00716 , B01J2219/0072 , B01J2219/00722 , C08F222/38 , C12Q1/6806 , C12Q1/6834 , C12Q1/6837 , C12Q1/6876 , C40B40/06 , C40B50/18 , Y10T428/265
摘要： Methods are disclosed relating to generating a silene-free slide comprising the steps of providing a plastic substrate; providing a solution of acrylamide comprising N-(5-bromoacetamidylpentyl) acrylamide (BRAPA); contacting the acrylamide/BRAPA solution with a polymerizing agent; contacting the acrylamide/BRAPA solution with an oxidizing agent; and contacting the acrylamide/BRAPA/polymerizing agent/oxidizing agent to the plastic substrate.
摘要翻译： 公开了关于产生无硅胶片的方法，包括提供塑料基材的步骤; 提供包含N-（5-溴乙酰氨基戊基）丙烯酰胺（BRAPA）的丙烯酰胺溶液; 使丙烯酰胺/ BRAPA溶液与聚合剂接触; 使丙烯酰胺/ BRAPA溶液与氧化剂接触; 并使丙烯酰胺/ BRAPA /聚合剂/氧化剂与塑料基材接触。
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公开(公告)号：US08969258B2
公开(公告)日：2015-03-03
申请号：US14053333
申请日：2013-10-14
发明人： Mark Edward Brennan Smith , Andrea Sabot , Isabelle Marie Julia Rasolonjatovo , Jean-Ernest Sohna Sohna , Adrian Martin Horgan , Harold Philip Swerdlow
CPC分类号： B01J19/0046 , B01J2219/00351 , B01J2219/00527 , B01J2219/00529 , B01J2219/00585 , B01J2219/00596 , B01J2219/00605 , B01J2219/00608 , B01J2219/0061 , B01J2219/00612 , B01J2219/00617 , B01J2219/00626 , B01J2219/00637 , B01J2219/00639 , B01J2219/00641 , B01J2219/00716 , B01J2219/0072 , B01J2219/00722 , C08F222/38 , C12Q1/6806 , C12Q1/6834 , C12Q1/6837 , C12Q1/6876 , C40B40/06 , C40B50/18 , Y10T428/265
摘要： Methods are disclosed relating to localizing nucleic acids to arrays such as silane-free arrays, and of sequencing the nucleic acids localized thereby.
摘要翻译： 公开了将核酸定位到诸如无硅烷基阵列的阵列以及对其定位的核酸进行测序的方法。
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