-
公开(公告)号：US20180222882A1
公开(公告)日：2018-08-09
申请号：US15801201
申请日：2017-11-01
Applicant: Genentech, Inc.
Inventor： Benjamin Fauber , Monique Bodil van Niel , Andrew Cridland , Christopher Hurley , Jonathan Killen , Stuart Ward
IPC: C07D401/04 , C07D403/04 , C07D405/04 , C07D413/14 , C07D403/14 , C07D405/14 , C07D401/14 , C07D491/107 , A61P19/02 , A61P25/28 , A61P17/06 , A61P1/00 , A61P11/00 , A61P11/06
CPC classification number: C07D401/04 , A61P1/00 , A61P11/00 , A61P11/06 , A61P17/06 , A61P19/02 , A61P25/28 , C07D401/14 , C07D403/04 , C07D403/14 , C07D405/04 , C07D405/14 , C07D413/14 , C07D491/107
Abstract: Compounds of formula I: or pharmaceutical salts thereof, wherein m, n, A, R1, R2, R3, R4 and R5 are as defined herein. Also disclosed are methods of making the compounds and using the compounds for treatment of inflammatory diseases such as arthritis.
-
公开(公告)号：US11008312B2
公开(公告)日：2021-05-18
申请号：US16398795
申请日：2019-04-30
Applicant: Genentech, Inc.
Inventor： Sarah M. Bronner , James J. Crawford , Andrew Cridland , Patrick Cyr , Benjamin Fauber , Emanuela Gancia , Alberto Gobbi , Christopher Hurley , Jonathan Killen , Wendy Lee , Olivier Rene , Monique Bodil Van Niel , Stuart Ward , Paul Winship , Jason Zbieg
IPC: C07D413/14 , C07D403/14 , C07D405/14 , C07D409/14 , C07D401/14
Abstract: Compounds of formula I: or pharmaceutical salts thereof, wherein m, n, p, q A, B, R1, R2, R3, R4, R5, R6 and R7 are as defined herein. Also disclosed are methods of making the compounds and using the compounds for treatment of inflammatory diseases such as arthritis.
-
公开(公告)号：US09994551B2
公开(公告)日：2018-06-12
申请号：US15801178
申请日：2017-11-01
Applicant: Genentech, Inc.
Inventor： Benjamin Fauber , Monique Bodil van Niel , Andrew Cridland , Christopher Hurley , Jonathan Killen , Stuart Ward , Paul Winship
IPC: C07D403/12 , C07D237/26 , C07D401/12 , C07D401/14 , C07D403/14 , C07D413/04 , C07D413/14 , C07D471/04 , C07D487/04
CPC classification number: C07D403/12 , C07D237/26 , C07D237/28 , C07D401/12 , C07D401/14 , C07D403/14 , C07D405/12 , C07D413/04 , C07D413/12 , C07D413/14 , C07D471/04 , C07D487/04
Abstract: Compounds of formula I: or pharmaceutical salts thereof, wherein R1, R2, R3 and R4 are as defined herein. Also disclosed are methods of making the compounds and using the compounds for treatment of inflammatory diseases such as arthritis.
-
公开(公告)号：US20140163024A1
公开(公告)日：2014-06-12
申请号：US14101566
申请日：2013-12-10
Applicant: Genentech, Inc.
Inventor： Benjamin Fauber , Olivier Rene , Monique Bodil van Niel , Simon Gaines , Jonathan Killen , Stuart Ward
IPC: C07D295/26 , C07D295/096 , C07D401/12 , C07D295/185 , C07D211/58 , C07D211/96
CPC classification number: C07D295/26 , C07D211/46 , C07D211/58 , C07D211/62 , C07D211/96 , C07D295/096 , C07D295/116 , C07D295/185 , C07D401/12
Abstract: Compounds of the formula Ia or Ib: or pharmaceutically acceptable salts thereof, wherein m, n, p, q, r, A, X1, X2, X3, X4, Y, Z, R1, R2, R3, R4, R5, R6, R7, and R8 are as defined herein. Also disclosed are methods of making the compounds and using the compounds for treatment of inflammatory diseases such as arthritis.
Abstract translation: 式Ia或Ib化合物或其药学上可接受的盐，其中m，n，p，q，r，A，X 1，X 2，X 3，X 4，Y，Z，R 1，R 2，R 3，R 4，R 5，R 6 ，R7和R8如本文所定义。 还公开了制备化合物和使用该化合物治疗炎性疾病如关节炎的方法。
-
公开(公告)号：US20190263794A1
公开(公告)日：2019-08-29
申请号：US16398795
申请日：2019-04-30
Applicant: Genentech, Inc.
Inventor： Sarah M. Bronner , James J. Crawford , Andrew Cridland , Patrick Cyr , Benjamin Fauber , Emanuela Gancia , Alberto Gobbi , Christopher Hurley , Jonathan Killen , Wendy Lee , Olivier Rene , Monique Bodil Van Niel , Stuart Ward , Paul Winship , Jason Zbieg
IPC: C07D413/14 , C07D403/14 , C07D405/14
Abstract: Compounds of formula I: or pharmaceutical salts thereof, wherein m, n, p, q A, B, R1, R2, R3, R4, R5, R6 and R7 are as defined herein. Also disclosed are methods of making the compounds and using the compounds for treatment of inflammatory diseases such as arthritis.
-
Patent Agency Ranking
公开(公告)号：US10280144B2
公开(公告)日：2019-05-07
申请号：US15801192
申请日：2017-11-01
Applicant: Genentech, Inc.
Inventor： Benjamin Fauber , James J. Crawford , Sarah M. Bronner , Monique Bodil van Niel , Andrew Cridland , Emanuela Gancia , Christopher Hurley , Jonathan Killen , Stuart Ward
IPC: C07D237/26 , C07D237/28
Abstract: Compounds of formula I: or pharmaceutical salts thereof, wherein m, A, X, Y, Z, R1, R2, R3, R4 and R5 are as defined herein. Also disclosed are methods of making the compounds and using the compounds for treatment of inflammatory diseases such as arthritis.
-
公开(公告)号：US09981916B2
公开(公告)日：2018-05-29
申请号：US14533358
申请日：2014-11-05
Applicant: Genentech, Inc.
Inventor： Monique Bodil van Niel , Andrew Cridland , Benjamin Fauber , Alberto Gobbi , Christopher Hurley , David Hurst , Jonathan Killen , Robert Maxey , Stuart Ward
IPC: C07D237/28 , C07D403/06 , C07D413/06 , C07D401/04 , C07D417/04 , C07D405/12 , C07D491/048 , C07D403/14 , C07D491/107 , C07D401/12
CPC classification number: C07D237/28 , C07D401/04 , C07D401/12 , C07D403/06 , C07D403/14 , C07D405/12 , C07D413/06 , C07D417/04 , C07D491/048 , C07D491/107
Abstract: Compounds of the formula I: or a pharmaceutical salt thereof, wherein X, Ar1, R1, R2, R3, R4, R5, R6 and R7 are as defined herein. Also disclosed are methods of making the compounds and using the compounds for treatment of inflammatory diseases such as arthritis.
-
公开(公告)号：US20180072683A1
公开(公告)日：2018-03-15
申请号：US15801192
申请日：2017-11-01
Applicant: Genentech, Inc.
Inventor： Benjamin Fauber , James J. Crawford , Sarah M. Bronner , Monique Bodil van Niel , Andrew Cridland , Emanuela Gancia , Christopher Hurley , Jonathan Killen , Stuart Ward
IPC: C07D237/26
CPC classification number: C07D237/26 , C07D237/28
Abstract: Compounds of formula I: or pharmaceutical salts thereof, wherein m, A, X, Y, Z, R1, R2, R3, R4 and R5are as defined herein. Also disclosed are methods of making the compounds and using the compounds for treatment of inflammatory diseases such as arthritis.
-
公开(公告)号：US20180051010A1
公开(公告)日：2018-02-22
申请号：US15801178
申请日：2017-11-01
Applicant: Genentech, Inc.
Inventor： Benjamin Fauber , Monique Bodil van Niel , Andrew Cridland , Christopher Hurley , Jonathan Killen , Stuart Ward , Paul Winship
IPC: C07D403/12 , C07D403/14 , C07D401/14 , C07D401/12 , C07D237/26 , C07D487/04 , C07D471/04 , C07D413/14 , C07D413/04
CPC classification number: C07D403/12 , C07D237/26 , C07D237/28 , C07D401/12 , C07D401/14 , C07D403/14 , C07D405/12 , C07D413/04 , C07D413/12 , C07D413/14 , C07D471/04 , C07D487/04
Abstract: Compounds of formula I: or pharmaceutical salts thereof, wherein R1, R2, R3 and R4 are as defined herein. Also disclosed are methods of making the compounds and using the compounds for treatment of inflammatory diseases such as arthritis.
-
公开(公告)号：US09382222B2
公开(公告)日：2016-07-05
申请号：US14101566
申请日：2013-12-10
Applicant: Genentech, Inc.
Inventor： Benjamin Fauber , Olivier Rene , Monique Bodil van Niel , Simon Gaines , Jonathan Killen , Stuart Ward
IPC: C07D241/04 , C07D295/00 , A61K31/497 , C07D295/26 , C07D211/58 , C07D211/96 , C07D295/096 , C07D295/185 , C07D401/12 , C07D211/46 , C07D295/116 , C07D211/62
CPC classification number: C07D295/26 , C07D211/46 , C07D211/58 , C07D211/62 , C07D211/96 , C07D295/096 , C07D295/116 , C07D295/185 , C07D401/12
Abstract: Compounds of the formula Ia or Ib: or pharmaceutically acceptable salts thereof, wherein m, n, p, q, r, A, X1, X2, X3, X4, Y, Z, R1, R2, R3, R4, R5, R6, R7, and R8 are as defined herein. Also disclosed are methods of making the compounds and using the compounds for treatment of inflammatory diseases such as arthritis.
Abstract translation: 式Ia或Ib化合物或其药学上可接受的盐，其中m，n，p，q，r，A，X 1，X 2，X 3，X 4，Y，Z，R 1，R 2，R 3，R 4，R 5，R 6 ，R7和R8如本文所定义。 还公开了制备化合物和使用该化合物治疗炎性疾病如关节炎的方法。
-
-
-
-
-
-
-
-
-
Search Results
11
records
(took 0.022 seconds)
