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公开(公告)号：US20240026317A1
公开(公告)日：2024-01-25
申请号：US18249023
申请日：2021-10-13
Applicant: Dong SHEN , David BROWN , Renxiang CHEN , RNAimmune, Inc
Inventor： Dong Shen , David Brown , Renxiang Chen
CPC classification number: C12N9/14 , C12Y306/05002 , C12P19/30 , A61K39/001164 , A61K9/1273 , A61K47/6911 , A61P35/00 , A61K47/54 , A61K2039/53 , A61K2039/585 , A61K2039/55555
Abstract: Compositions and methods are provided for potent mRNA vaccines for treatment of cancers with a mutation in the ras gene family. The compositions include a pharmaceutical composition comprising, or consisting essentially of, or yet further comprising mRNA molecules encoding at least one of multiple peptides of a group of somatic mutants and a pharmaceutically acceptable carrier. Methods for stimulating system immune responses and treatment are provided, including intratumoral, intravenous, intramuscular, intradermal, or subcutaneous injection of the composition as disclosed herein.
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公开(公告)号：US20130295249A1
公开(公告)日：2013-11-07
申请号：US13822086
申请日：2011-09-08
Applicant: Rebecca Hwee Peng Lian , Dong Shen , Helge Ulmer , Chang Liu
Inventor： Rebecca Hwee Peng Lian , Dong Shen , Helge Ulmer , Chang Liu
CPC classification number: A23L2/08 , A23B7/026 , A23L2/38 , A23L13/10 , A23L13/30 , A23L13/428 , A23L13/52 , A23L13/67 , A23L23/00 , A23L23/10 , A23L27/10 , A23L27/14 , A23P10/20 , A23P10/25
Abstract: A granulated food product comprising plant material from one or more aromatic plants, a meaty base and an osmotic agent, and a method for preparing a granulated food product comprising milling plant material from one or more aromatic plants together with a meaty base, mixing the milled material with an osmotic agent to form a viscous mixture, granulating the viscous mixture, and drying the granules.
Abstract translation: 一种包含来自一种或多种芳族植物，肉质基质和渗透剂的植物材料的颗粒状食品，以及制备颗粒状食品的方法，包括将一种或多种芳香植物与肉质基料一起研磨植物材料，将经研磨的 材料与渗透剂形成粘性混合物，造粒粘稠混合物，并干燥颗粒。
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3.发明申请公开(公告)号：US20120294349A1
公开(公告)日：2012-11-22
申请号：US13562507
申请日：2012-07-31
Applicant: Ming JIA , Wen TONG , Dong-Shen YU
Inventor： Ming JIA , Wen TONG , Dong-Shen YU
IPC: H04B1/10
CPC classification number: H04B7/0667 , H04B7/0848 , H04B7/0891 , H04L1/0045 , H04L1/0618 , H04L5/023 , H04L27/2647
Abstract: A level of interference affecting signal components of received communication signals is estimated and used to weight the signal components. The signal components in a each of a number of groups of signal components are weighted based on respective interference estimates to thereby adjust signal components for coloured interference, which may vary significantly between different groups of signal components. Each group of signal components may include a single component or components within a relatively narrow sub-band of the communication signals, such as a coherence bandwidth of an Orthogonal Frequency Division Multiplexing (OFDM) signal.
Abstract translation: 估计接收到的通信信号的影响信号分量的干扰电平，并用于加权信号分量。 基于相应的干扰估计来对多个信号分量组中的每一个中的信号分量进行加权，从而调整用于着色干扰的信号分量，其可以在不同的信号分量组之间显着变化。 每组信号分量可以包括通信信号的相对窄的子带内的单个分量，例如正交频分复用（OFDM）信号的相干带宽。
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公开(公告)号：US20120027130A1
公开(公告)日：2012-02-02
申请号：US13240727
申请日：2011-09-22
Applicant: Ming Jia , Wen Tong , Dong-Shen Yu
Inventor： Ming Jia , Wen Tong , Dong-Shen Yu
CPC classification number: H04B7/0667 , H04B7/0848 , H04B7/0891 , H04L1/0045 , H04L1/0618 , H04L5/023 , H04L27/2647
Abstract: A level of interference affecting signal components of received communication signals is estimated and used to weight the signal components. The signal components in a each of a number of groups of signal components are weighted based on respective interference estimates to thereby adjust signal components for coloured interference, which may vary significantly between different groups of signal components. Each group of signal components may include a single component or components within a relatively narrow sub-band of the communication signals, such as a coherence bandwidth of an Orthogonal Frequency Division Multiplexing (OFDM) signal.
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5.发明授权公开(公告)号：US08027417B2
公开(公告)日：2011-09-27
申请号：US10739044
申请日：2003-12-19
Applicant: Ming Jia , Wen Tong , Dong-Shen Yu
Inventor： Ming Jia , Wen Tong , Dong-Shen Yu
IPC: H04L1/06
CPC classification number: H04B7/0667 , H04B7/0848 , H04B7/0891 , H04L1/0045 , H04L1/0618 , H04L5/023 , H04L27/2647
Abstract: A level of interference affecting signal components of received communication signals is estimated and used to weight the signal components. The signal components in a each of a number of groups of signal components are weighted based on respective interference estimates to thereby adjust signal components for colored interference, which may vary significantly between different groups of signal components. Each group of signal components may include a single component or components within a relatively narrow sub-band of the communication signals, such as a coherence bandwidth of an Orthogonal Frequency Division Multiplexing (OFDM) signal.
Abstract translation: 估计接收到的通信信号的影响信号分量的干扰电平，并用于加权信号分量。 基于相应的干扰估计来对多个信号分量组中的每一个中的信号分量进行加权，从而调整用于着色干扰的信号分量，其可以在不同的信号分量组之间显着变化。 每组信号分量可以包括通信信号的相对窄的子带内的单个分量，例如正交频分复用（OFDM）信号的相干带宽。
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Patent Agency Ranking
公开(公告)号：US07919300B2
公开(公告)日：2011-04-05
申请号：US11597609
申请日：2004-07-28
Applicant: Jun Wang , Rongzhao Fu , Dong Shen , Caike Jin , Zhangming Liu , Junming Chen
Inventor： Jun Wang , Rongzhao Fu , Dong Shen , Caike Jin , Zhangming Liu , Junming Chen
CPC classification number: C12N9/92
Abstract: This invention describes a series of recombinant Thermoanaerobacterium saccharolyticum glucose isomerases having improved catalytic activity and thermostability. The recombinant glucose isomerases can be used for direct production of fructose syrup containing 55 wt % or higher concentration of fructose, or used for the production of fructose syrup containing less than 55 wt % fructose.
Abstract translation: 本发明描述了具有改进的催化活性和热稳定性的一系列重组的热酵母杆菌葡糖异构酶。 重组葡萄糖异构酶可用于直接生产含有55重量％或更高浓度果糖的果糖糖浆，或用于生产含有小于55重量％果糖的果糖糖浆。
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公开(公告)号：US20080305529A1
公开(公告)日：2008-12-11
申请号：US12093859
申请日：2006-10-30
Applicant: Jun Wang , Caike Jin , Rongzhao Fu , Dong Shen
Inventor： Jun Wang , Caike Jin , Rongzhao Fu , Dong Shen
Abstract: This invention provides a series of recombinant Thermoanaerobacterium saccharolyticum glucose isomerases with improved catalytic activity and thermostability obtained by using recombinant techniques. These recombinant glucose isomerases comprise amino acid variation including phenylalanine Phe) at position 139, alanine (Ala) at position 182, serine (Ser) at position 187, and glutamine (Gln) at position 299, and carry at least one additional mutated amino acid at position 87, position 217, position 260 or position 276, and possess a higher catalytic activity than that of the wild-type when using D-glucose as substrate. These recombinant glucose isomerases can be used for direct production of high fructose corn syrup containing 55.% [wt] or higher concentration of fructose.
Abstract translation: 本发明提供了一系列通过使用重组技术获得的具有改进的催化活性和热稳定性的重组热酵母杆菌葡萄糖异构酶。 这些重组葡萄糖异构酶包含位置139的氨基酸变异，包括苯丙氨酸Phe），182位丙氨酸（Ala），第187位的丝氨酸（Ser）和299位的谷氨酰胺（Gln），并携带至少一种另外的突变的氨基酸 在位置87，位置217，位置260或位置276，并且当使用D-葡萄糖作为底物时，具有比野生型更高的催化活性。 这些重组葡萄糖异构酶可用于直接生产含有55％（wt）或更高浓度果糖的高果糖玉米糖浆。
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公开(公告)号：US5184933A
公开(公告)日：1993-02-09
申请号：US661985
申请日：1991-02-27
Applicant: Zhong Pei-qian , Zheng Wen-kang , Xu Xi-tian , Liang Jian-he , Zhou Dong-shen , Yang Jun-zhi
Inventor： Zhong Pei-qian , Zheng Wen-kang , Xu Xi-tian , Liang Jian-he , Zhou Dong-shen , Yang Jun-zhi
Abstract: A mini-size universal hydraulic excavator capable of performing independently many operating processes, such as digging, pushing, grabbing, drilling and chipping, having essentially three main sections, namely, a chassis carrying traveling device pivotally connected with an earth-moving means, a complete swivel upper carriage provided with a power generator and a driver's seat, and an excavating arm having a boom, a bucket arm, and a bucket. A hydraulic chipper can be connected to the main machine without the necessity of removal of the bucket and the earth-moving means, so that chipping and site clearing can be carried on simultaneously solely by one single machine. A backhoe bucket carrying a scraper employs a multi-bar linkage mechanism having a bucket body, a scraper, and a bucket arm so that the bucket can have sufficient bucket capacity in a relatively greater excavating revolving angle range. Specially-set accessory operating equipment oil lines are used to drive all the hydraulic operation equipments except the bucket.
Abstract translation: 一种小型通用液压挖掘机，其能够独立地执行诸如挖掘，推动，抓取，钻孔和切屑的许多操作过程，其具有基本上三个主要部分，即与地球移动装置枢转连接的底盘承载行进装置， 具有动力发电机和驾驶员座椅的完整的转动上部托架，以及具有起重臂，铲斗和铲斗的挖掘臂。 液压切片机可以连接到主机，而不需要移除铲斗和移土装置，从而可以通过一台机器同时进行切屑和现场清理。 携带刮板的反铲斗采用具有铲斗本体，铲斗和铲斗臂的多杆连杆机构，使得铲斗能够在相对较大的挖掘旋转角度范围内具有足够的铲斗容量。 专用配套操作设备油路用于驱动除铲斗外的所有液压操作设备。
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公开(公告)号：US20150096751A1
公开(公告)日：2015-04-09
申请号：US14570003
申请日：2014-12-15
Applicant: Dong Shen , Leiming Li , Jia Zhou , Hong Sun
Inventor： Dong Shen , Leiming Li , Jia Zhou , Hong Sun
IPC: C09K8/80 , E21B43/267
CPC classification number: C09K8/80 , C09K8/524 , C09K8/528 , C09K8/685 , C09K8/88 , C09K8/92 , C09K2208/20 , C09K2208/22 , C09K2208/26 , C09K2208/32 , E21B43/267
Abstract: A hydraulic fracturing composition includes: a superabsorbent polymer in an expanded state; a plurality of proppant particles disposed in the superabsorbent polymer; a well treatment agent, and a fluid to expand the superabsorbent polymer into the expanded state. A process for treating a well with well treatment agent includes disposing a hydraulic fracturing composition comprising the well treatment agent in a well. The well treatment agent can be a scale inhibitor, tracer, pH buffering agent, or a combination thereof.
Abstract translation: 水力压裂组合物包括：膨胀状态的超吸收性聚合物; 设置在超吸收性聚合物中的多个支撑剂颗粒; 井处理剂和将超吸收性聚合物膨胀成膨胀状态的流体。 用井处理剂处理井的方法包括将包含井处理剂的水力压裂组合物置于井中。 该处理剂可以是阻垢剂，示踪剂，pH缓冲剂或其组合。
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10.发明授权公开(公告)号：US08644412B2
公开(公告)日：2014-02-04
申请号：US13562507
申请日：2012-07-31
Applicant: Ming Jia , Wen Tong , Dong-Shen Yu
Inventor： Ming Jia , Wen Tong , Dong-Shen Yu
CPC classification number: H04B7/0667 , H04B7/0848 , H04B7/0891 , H04L1/0045 , H04L1/0618 , H04L5/023 , H04L27/2647
Abstract: A level of interference affecting signal components of received communication signals is estimated and used to weight the signal components. The signal components in a each of a number of groups of signal components are weighted based on respective interference estimates to thereby adjust signal components for colored interference, which may vary significantly between different groups of signal components. Each group of signal components may include a single component or components within a relatively narrow sub-band of the communication signals, such as a coherence bandwidth of an Orthogonal Frequency Division Multiplexing (OFDM) signal.
Abstract translation: 估计接收到的通信信号的影响信号分量的干扰电平，并用于加权信号分量。 基于相应的干扰估计来对多个信号分量组中的每一个中的信号分量进行加权，从而调整用于着色干扰的信号分量，其可以在不同的信号分量组之间显着变化。 每组信号分量可以包括通信信号的相对窄的子带内的单个分量，例如正交频分复用（OFDM）信号的相干带宽。
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