Systems and methods for particle counting
    81.
    发明申请
    Systems and methods for particle counting 有权
    粒子计数的系统和方法

    公开(公告)号:US20070143033A1

    公开(公告)日:2007-06-21

    申请号:US11312722

    申请日:2005-12-20

    IPC分类号: G06F19/00

    摘要: Systems and methods consistent with embodiments of the present invention provide a method for the measurement and analysis of particle counts in flow cytometry and hematology instruments. In some methods for the measurement and analysis of particle counts, a corrected histogram of particle distributions is calculated and used to obtain an accurate count of particles and an accurate measurement of other particle parameters.

    摘要翻译: 与本发明的实施方案一致的系统和方法提供了流式细胞术和血液学仪器中的颗粒计数的测量和分析方法。 在一些用于测量和分析颗粒计数的方法中,计算颗粒分布的校正直方图并用于获得精确的颗粒计数和其他颗粒参数的精确测量。

    Substrate cleaning method
    83.
    发明申请
    Substrate cleaning method 有权
    基材清洗方法

    公开(公告)号:US20060016462A1

    公开(公告)日:2006-01-26

    申请号:US11235008

    申请日:2005-09-21

    申请人: Toru Asano

    发明人: Toru Asano

    IPC分类号: B08B7/04 B08B3/00 A47L15/00

    摘要: A substrate cleaning apparatus includes an indexer, a front surface cleaning unit for cleaning the front surface of a substrate, a back surface cleaning unit for cleaning the back surface of the substrate, a particle inspecting unit for detecting a distribution of particles adhering to the substrate, a reversing unit for reversing the substrate, and a transport section having a pair of transport units. Cleaning conditions of the front surface cleaning unit or back surface cleaning unit are varied based on the distribution of particles on the substrate after the substrate is cleaned by the front surface cleaning unit or back surface cleaning unit and inspected by the particle inspecting unit.

    摘要翻译: 一种基板清洗装置,包括分度器,用于清洁基板前表面的前表面清洁单元,用于清洁基板背面的后表面清洁单元,用于检测附着在基板上的颗粒分布的颗粒检查单元 ,用于反转基板的反转单元和具有一对输送单元的输送部。 前表面清洁单元或后表面清洁单元的清洁条件基于在通过前表面清洁单元或背面清洁单元清洁基板并由颗粒检查单元检查之后基板上的颗粒的分布而变化。

    Automatic sample analyzer and its components
    86.
    发明授权
    Automatic sample analyzer and its components 有权
    自动样品分析仪及其组件

    公开(公告)号:US06938502B2

    公开(公告)日:2005-09-06

    申请号:US10899172

    申请日:2004-07-27

    摘要: An automatic sample analyzer includes: a pipette, a pipette driving device which moves the pipette to a sample vessel present in a predetermined position to cause the pipette to suck up a sample from the sample vessel, and then moves the pipette to an open vessel provided in another predetermined position to cause the pipette to discharge the sample into the open vessel, and an analyzing section for analyzing the discharged sample, the pipette driving device comprising a vertically movable main arm and an elongated guide arm cantilevered by the main arm and extending horizontally, the guide arm having a smaller flexural rigidity than the main arm, wherein the main arm vertically moves the pipette when the sample is to be sucked up from the sample vessel, and the guide arm guides the pipette to the open vessel and then vertically moves the pipette when the sample is to be discharged into the open vessel.

    摘要翻译: 自动样品分析仪包括:移液管,移液管驱动装置,其将移液管移动到存在于预定位置的样品容器中,以使移液管从样品容器中吸取样品,然后将移液管移动到提供的开放容器 在另一预定位置使吸液管将样品排放到开放容器中,以及用于分析排出的样品的分析部分,该移液管驱动装置包括一个可垂直移动的主臂和一个由主臂悬臂伸展并伸长的细长引导臂 所述引导臂具有比所述主臂更小的弯曲刚度,其中当所述样品要从所述样品容器中吸出时,所述主臂垂直移动所述移液管,并且所述引导臂将所述移液管引导到所述开放容器,然后垂直移动 当样品被排放到开放式容器中时的移液管。

    METHOD FOR MEASUREMENT OF NUCLEATED RED BLOOD CELLS
    89.
    发明申请
    METHOD FOR MEASUREMENT OF NUCLEATED RED BLOOD CELLS 有权
    核红细胞测量方法

    公开(公告)号:US20030235917A1

    公开(公告)日:2003-12-25

    申请号:US10226800

    申请日:2002-08-23

    IPC分类号: G01N031/00 G01N033/48

    摘要: A method for differentiating and enumerating nucleated red blood cells in a blood sample is described. The method includes the steps of lysing red blood cells of a blood sample with a lytic reagent, measuring nucleated blood cells by DC impedance measurement in a non-focused flow aperture, differentiating nucleated red blood cells from other cell types, and reporting nucleated red blood cells in the blood sample. The method further includes subtracting nucleated red blood cells and other interference materials from the count of remaining blood cells, and reporting a corrected white blood cell count of the blood sample. Additionally, the method further includes measuring spectrophotometric absorbance of the sample mixture at a predetermined wavelength of a hemoglobin chromogen formed upon lysing the blood sample, and reporting hemoglobin concentration of the blood sample.

    摘要翻译: 描述了一种用于分离和计数血液样品中有核红细胞的方法。 该方法包括用溶解试剂裂解血液样品的红细胞的步骤,通过非聚焦流动孔中的直流阻抗测量测量有核血细胞,将有核红细胞与其他细胞类型区分开,并报告有核红血 血样中的细胞。 该方法还包括从剩余血细胞计数中减去有核红细胞和其他干扰物质,并报告血样的校正白细胞计数。 此外,该方法还包括在裂解血液样品时形成的血红蛋白色原体的预定波长测量样品混合物的分光光度吸光度,并报告血液样品的血红蛋白浓度。

    MEMS-based integrated magnetic particle identification system
    90.
    发明授权
    MEMS-based integrated magnetic particle identification system 有权
    基于MEMS的集成磁粉识别系统

    公开(公告)号:US06623984B1

    公开(公告)日:2003-09-23

    申请号:US09704298

    申请日:2000-11-01

    IPC分类号: G01N33553

    摘要: The present invention provides a MEMS-based integrated particle identification system having a substrate, a magnetic structure, and a bioferrograph. The substrate includes a topside portion, backside portion and a flow system. The flow system includes a flow channel for accepting the flow of a stream of particles to identified. The magnetic structure is in physical communication with the topside and backside portions of the substrate and has at least two pole pieces. A plurality of pole piece embodiments are provided for generating a magnetic field that acts on magnetically susceptible particles in the flow stream. The bioferrograph has at least one sensor for identifying the presence and quantity of magnetically susceptible particles. A plurality of sensor embodiments are also provided.

    摘要翻译: 本发明提供了一种基于MEMS的集成粒子识别系统,该系统具有基底,磁性结构和生物计量学。 衬底包括顶侧部分,后侧部分和流动系统。 流动系统包括用于接收所识别的颗粒物流的流动通道。 磁性结构与衬底的顶侧和后侧部分物理连通,并具有至少两个极片。 提供了多个极片实施例,用于产生作用在流动流中的易磁敏颗粒上的磁场。 生物传感器具有至少一个用于识别磁敏感颗粒的存在和数量的传感器。 还提供了多个传感器实施例。