-
公开(公告)号:US20240269468A1
公开(公告)日:2024-08-15
申请号:US18635518
申请日:2024-04-15
Applicant: California Institute of Technology , University of Louisville Research Foundation, Inc. , The Regents of the University of California
Inventor: Victor Reggie EDGERTON , Roland R. ROY , Yury GERASIMENKO , Joel W. BURDICK , Susan J. HARKEMA , Jonathan HODES , Yu-Chong TAI , Mandheerej S. NANDRA , Claudia A. ANGELI , Thomas Anthony DESAUTELS
CPC classification number: A61N1/36103 , A61H1/0237 , A61H1/0274 , A61N1/0551 , A61N1/0553 , A61N1/0556 , A61N1/36003 , A63B21/00181 , A61N1/3616 , A63B22/0235 , A63B69/0064 , A63B2213/004 , A63B2220/805 , A63B2230/60 , F04C2270/0421
Abstract: A system and methods are disclosed for enabling or improving control of cardiovascular and/or vasomotor autonomic functions in a patient having a neurologically derived paralysis or a nervous system disorder.
-
公开(公告)号:US20240189583A1
公开(公告)日:2024-06-13
申请号:US18582060
申请日:2024-02-20
Inventor: Jonathan Isaacs , Isaac Perry Clements , Andrew Willsie , James David Ross , Alex Weidenbach
CPC classification number: A61N1/0556 , A61B5/24 , A61B5/6877 , A61B5/6882 , A61N1/0558 , A61N1/36103
Abstract: An example device for repairing a tissue is described herein. The device can include a flexible carrier layer, and a support member including a plurality of micro-protrusions extending therefrom. The support member can be at least partially integrated with the flexible carrier layer. Additionally, the flexible carrier layer can be configured to cover at least a portion of the tissue, and the micro-protrusions can be configured to mechanically interface with the tissue.
-
公开(公告)号:US20240157159A1
公开(公告)日:2024-05-16
申请号:US18351338
申请日:2023-07-12
Applicant: Epic Neuro, Inc.
Inventor: James William PHILLIPS
CPC classification number: A61N1/3787 , A61N1/0531 , A61N1/3606 , A61N1/36064 , A61N1/36067 , A61N1/36071 , A61N1/36075 , A61N1/36103 , A61N1/36139 , A61N1/36171 , A61N1/0529 , A61N1/0534 , A61N1/36082
Abstract: A method and device is described, which provides electrical stimulation to the brain of a person, where the device comprises an external portion and at least one implantable portion. The external portion provides the energy source for stimulation to the implantable portions. The implantable portions provide at least two conductive paths through the skull and use the skull's high impedance to generate a current loop with the focus of stimulation lying in the current path.
-
公开(公告)号:US20240157146A1
公开(公告)日:2024-05-16
申请号:US18544384
申请日:2023-12-18
Applicant: Newton Howard
Inventor: Newton Howard
IPC: A61N1/36 , A61B5/384 , A61N5/06 , C01B32/158
CPC classification number: A61N1/36103 , A61B5/384 , A61N5/0601 , A61N5/0622 , C01B32/158 , A61N2005/063 , C01B2202/22
Abstract: For example, in an embodiment, an implant device may comprise a plurality of fibers adapted to receive electrical signals, optical signals, or both electrical and optical signals from neural signals of the brain tissue and to transmit signals, to provide stimulation of the brain tissue, and a controller to receive signals, determine direct neural connections by analyzing waveforms and propagation delays of the received signals, recognize at least one dead or non-functional neuron and determine direct neural connections affected by the at least one dead or non-functional neuron, and forward neural signals around the at least one dead or non-functional neuron by recording the received signals from one side of the at least one dead or non-functional neuron and transmitting the recorded signals to stimulate an other side of the at least one dead or non-functional neuron.
-
公开(公告)号:US11963714B2
公开(公告)日:2024-04-23
申请号:US17347179
申请日:2021-06-14
Inventor: Mark E. Deem , Hanson S. Gifford, III , Denise Zarins , Douglas Sutton , Erik Thai , Mark Gelfand , Howard R. Levin
IPC: A61B18/14 , A61B8/08 , A61B8/12 , A61B18/00 , A61B18/12 , A61B18/18 , A61M5/14 , A61M25/00 , A61N1/04 , A61N1/05 , A61N1/18 , A61N1/20 , A61N1/32 , A61N1/36 , A61N5/00 , A61N7/00
CPC classification number: A61B18/1492 , A61B8/0891 , A61B8/12 , A61B18/1206 , A61B18/1233 , A61B18/18 , A61M5/14 , A61M25/0023 , A61N1/05 , A61N1/0551 , A61N1/18 , A61N1/205 , A61N1/327 , A61N1/36007 , A61N1/36017 , A61N1/36057 , A61N1/36103 , A61N1/36114 , A61N1/36139 , A61N5/00 , A61N7/00 , A61B2018/00071 , A61B2018/00214 , A61B2018/0022 , A61B2018/00267 , A61B2018/00404 , A61B2018/00434 , A61B2018/00505 , A61B2018/00511 , A61B2018/00577 , A61B2018/00613 , A61B2018/00642 , A61B2018/00904 , A61B2018/126 , A61B2018/1467 , A61N1/0412 , A61N1/326 , A61N1/36117 , A61N2007/0021 , A61N2007/003
Abstract: Methods and apparatus are provided for renal neuromodulation using a pulsed electric field to effectuate electroporation or electrofusion. It is expected that renal neuromodulation (e.g., denervation) may, among other things, reduce expansion of an acute myocardial infarction, reduce or prevent the onset of morphological changes that are affiliated with congestive heart failure, and/or be efficacious in the treatment of end stage renal disease. Embodiments of the present invention are configured for percutaneous intravascular delivery of pulsed electric fields to achieve such neuromodulation.
-
公开(公告)号:US20240082571A1
公开(公告)日:2024-03-14
申请号:US18514470
申请日:2023-11-20
Applicant: Case Western Reserve University
Inventor: Tina L. Vrabec , Kevin L. Kilgore , Niloy Bhadra , Laura Shaw , David Roberts , Narendra Bhadra
CPC classification number: A61N1/0551 , A61N1/20 , A61N1/36067 , A61N1/36103
Abstract: Systems and methods that deliver a continuous partial nerve conduction block are described. A waveform generator can configure one or more direct current (DC) waveforms to provide a continuous partial nerve conduction block. One or more electrodes can deliver the one or more DC waveforms to provide the partial block to the neural structure. Feedback can be provided to the waveform generator related to the partial block. The feedback includes monitoring a property associated with the partial block and altering a parameter associated with the one or more direct current waveforms in response to the property associated with the partial block.
-
公开(公告)号:US20240075294A1
公开(公告)日:2024-03-07
申请号:US18388659
申请日:2023-11-10
Applicant: THERANICA BIO-ELECTRONICS LTD.
Inventor: Alon IRONI , Lana VOLOKH
IPC: A61N1/36
CPC classification number: A61N1/36103 , A61N1/36128 , A61N1/36132 , A61N1/36071 , A61N1/37247
Abstract: Sensitivity of sensory nerves of a body portion is increased by activating at least one computer processor to iteratively simultaneously apply sets of electrical stimulation pulses to two locations upon a surface of the body portion; receive an input indicative of whether the subject sensed the sets of electrical stimulation pulses as having been applied to a single location or more than one location; in response to the input, designate another set of two locations upon the surface of the body portion at which to simultaneously apply sets of electrical stimulation pulses, the two locations being separated from each other by a distance that is different from the initial distance; and simultaneously apply sets of electrical stimulation pulses to the other set of at least two locations upon the surface of the body portion. Other configurations are also described.
-
88.
公开(公告)号:US20240032815A1
公开(公告)日:2024-02-01
申请号:US18546775
申请日:2022-06-27
Inventor: Kecheng Wei , Wei Zhang , Qiong Zhang
CPC classification number: A61B5/055 , A61B5/7225 , A61N1/36103 , A61B5/0037
Abstract: The present disclosure provides a target identification method, a target identification device, an electronic apparatus, a storage medium and a neuromodulation apparatus. The target identification method includes: acquiring scan data of a subject, the scan data including data obtained from magnetic resonance imaging of the subject's brain; determining the corresponding relationship of regions of interest of a disease type of the subject according to the disease type of the subject; determining at least one disease region of interest and at least one target region of interest of the subject in the scan data according to the corresponding relationship of the regions of interest; determining connectivity between each of voxels in the target region of interest and each disease region of interest in the at least one disease region of interest; and determining the positions of the voxels with the connectivity meeting a preset target connectivity condition in the target region of interest as the targets.
-
公开(公告)号:US11878170B2
公开(公告)日:2024-01-23
申请号:US17269156
申请日:2019-08-14
Applicant: CORSTIM
Inventor: Anne Beuter , Vitaly Volpert
CPC classification number: A61N1/36103 , A61N1/0531 , A61N1/36139
Abstract: An apparatus for electrical brain stimulation comprises a two dimensional electrode array designed to be implanted at the surface of the cortex of a person, said cortex having neural pre-identified nodes and including healthy cortical tissue and damaged cortical tissue, said damaged cortical tissue having at least one parameter of cortical waves which is different from parameter of healthy cortical tissue, said at least one parameter being one of cortical wave propagation speed, amplitude and frequency, said electrode array including electrodes for emitting stimulation electrical signals in the cortex and measuring electrical cortical waves in the cortex, and said electrode array being designed to cover at least part of said healthy cortical tissue and said damaged cortical tissue.
-
公开(公告)号:US11766567B2
公开(公告)日:2023-09-26
申请号:US17123331
申请日:2020-12-16
Applicant: CHECKPOINT SURGICAL, INC.
Inventor: Kevin Scanlan , Eric R. Walker , Leonard M. Cosentino
CPC classification number: A61N1/36103 , A61N1/0464 , A61N1/0551 , A61N1/36017 , A61N1/36167
Abstract: A stimulation device includes an adaptor component. The adaptor component couples a percutaneous lead to the stimulation device. The stimulation device may apply a stimulation signal to target tissue via the adaptor. A surgeon may place the stimulation device in a container and the adaptor component may be disposed outside of the container. Methods describe prolonged stimulation of target tissue via a stimulation device. The prolonged stimulation may be applied during and after a surgical procedure.
-
-
-
-
-
-
-
-
-