摘要:
Document image data is converted into luminance image data. Block image data is generated from the luminance image data. Start point block pixel data and end point block pixel data are set based on a change rate of luminance values of adjacent block pixel data. A luminance value of block pixel data between the start point block pixel data and the end point block pixel data is corrected based on a start point luminance value and an end point luminance value. The luminance value, of the block pixel data wherein each luminance value of an adjacent block pixel data cluster is less than an average value, is substituted by the average value. The luminance value of each pixel data is set based on the luminance value of the block pixel data. Post process luminance image data that includes each pixel data is reconverted into the document image data.
摘要:
An object of the present invention is to provide a novel and excellent agent for treating or preventing dementia, schizophrenia and the like, based on the 5-HT5A receptor modulating action. It was confirmed that a compound characterized by a structure that a tricyclic hetero ring having a pyrrole ring at the center and guanidine are bonded via a carbonyl group has a potent 5-HT5A receptor modulating action and an excellent pharmacological action based thereon, and thus, it was found that the compound can be an excellent agent for treating or preventing dementia, schizophrenia, bipolar disorder, or attention deficit hyperactivity disorder, particularly for memory-related functional disorders such as cognitive impairments including dementia and schizophrenia, thereby completing the present invention.
摘要:
A medical suturing and ligating apparatus is provided which enable to cut a suturing and ligating member such as a ligating wire in a simple manner while preventing a holding member from being removed from a flexible sheath. When a slider 32 pulls a ligating wire 18 toward the proximal end of an inner sheath 7 so as to suture or ligate a living tissue with the ligating wire 18 when a wire holding member is in abutting contact with the distal end of the inner sheath 7, a fixing screw 40 engages with an engaging recessed portion 41. As a result, the slider 32 is fixedly held on an operating section body 31. Accordingly, it is possible to maintain the state in which the wire holding member is in abutting contact with the distal end of the inner sheath.
摘要:
A refrigerator for cooling a space inside thereof with a Stirling refrigerating engine includes state detection means for detecting an excessive cooling critical state of the Stirling refrigerating engine and excessive cooling prevention means for preventing excessive cooling of the Stirling refrigerating engine based on detection of the excessive cooling critical state by the state detection means. Excessive cooling of the Stirling refrigerating engine can thus be prevented.
摘要:
A ligature and suture device for medical application includes a distal end insertion portion, a needle body, a ligature tool, and an operation section. The operation section includes a housing that is provided in a base end portion of the distal end insertion portion, a puncture handle that is provided in the housing so as to be able to move freely backwards and forwards and that drives the needle body, a pressing handle that is provided in the housing so as to be able to move freely backwards and forwards and that drives a pressing member, a ligature tool operation unit that is provided in the housing so as to be able to move freely backwards and forwards and that drives a ligature sheath, and a ligature handle that is provided in the ligature tool operation unit so as to be able to move freely backwards and forwards and that drives an engaging portion.
摘要:
An apparatus includes a crushing part which rotates and crushes the calculus, wherein a radius of rotation of the crushing part with respect to a rotation axis thereof increases or decreases in accordance with a rotation speed of the crushing part.
摘要:
A solid-concentration measuring apparatus includes an ultrasonic transmitter, an ultrasonic receiver, and a response-time integrator. The ultrasonic transmitter transmits a single-pulse ultrasonic wave to a liquid toner. The ultrasonic receiver receives the single-pulse ultrasonic wave. The ultrasonic transmitter transmits again a single-pulse ultrasonic wave after a predetermined time has passed from when the ultrasonic receiver receives the single-pulse ultrasonic wave. The response-time integrator measures a response time from transmission to reception of each single-pulse ultrasonic wave, and integrates the response time with respect to each set of N pulses (N>1). A solid concentration of the liquid toner is calculated based on the integrated response time.
摘要:
There is provided a compound having a capsaicin receptor VR1 inhibitory activity and useful as a therapeutic agent for various pains including inflammatory pain and neurogenic pain, migraine, cluster headache, bladder diseases including overactive bladder, and the like. A benzamide derivative or a salt thereof wherein a benzene ring is attached to a D ring (a monocyclic or bicyclic hydrocarbon ring or a monocyclic or bicyclic heteroaromatic ring) through an amide bond, the benzene ring is directly bonded to an E ring (a monocyclic or bicyclic hydrocarbon ring or a monocyclic or bicyclic heteroaromatic ring), and the benzene ring is further bonded to A (an amino moiety, a monocyclic or bicyclic heterocycle) through L (a lower alkylene).
摘要:
A ligature and suture device for medical application includes a distal end insertion portion, a needle body, a ligature tool, and an operation section. The operation section includes a housing that is provided in a base end portion of the distal end insertion portion, a puncture handle that is provided in the housing so as to be able to move freely backwards and forwards and that drives the needle body, a pressing handle that is provided in the housing so as to be able to move freely backwards and forwards and that drives a pressing member, a ligature tool operation unit that is provided in the housing so as to be able to move freely backwards and forwards and that drives a ligature sheath, and a ligature handle that is provided in the ligature tool operation unit so as to be able to move freely backwards and forwards and that drives an engaging portion.
摘要:
This invention comprises acquiring information about connection time, information about an amount of transmitted and received data during the connection time and information about line speed during the connection time for a specific user, judging whether a utilization state of a specific user is in a predetermined state by using the information about the connection time, the information about the amount of the transmitted and received data and the information about the line speed, and sending a notification concerning the specific user to the specific user, or to a manager or the like, if it is judged that the utilization state of the specific user is in the predetermined state. Thus, a notification concerning a user having a low utilization degree can be made, and therefore, improvement of the utilization rate can be encouraged.