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公开(公告)号：US20170072399A1
公开(公告)日：2017-03-16
申请号：US15360691
申请日：2016-11-23
Applicant: CALIFORNIA INSTITUTE OF TECHNOLOGY
Inventor： Aditya RAJAGOPAL , Samson CHEN , Axel SCHERER , Christopher I. WALKER
CPC classification number: B01L7/52 , B01L3/502707 , B01L2200/147 , B01L2300/0816 , B01L2300/0893 , B01L2300/12 , B01L2300/123 , B01L2300/1827 , B01L2300/1844 , C12Q1/686 , H05K1/0212 , H05K1/0272 , H05K1/028 , H05K3/46 , H05K3/4697 , Y10T29/49124
Abstract: PC board fluidic devices for performing a Polymerase Chain Reaction (PCR) are disclosed. The devices comprise a printed circuit board and a PCR chamber. The PCR chamber is a fluidic chamber and is located in, or is part of, the PC board. The PC board can include a coil trace heating element with a temperature sensor and controller.
Abstract translation: 公开了用于进行聚合酶链式反应（PCR）的PC板流体装置。 这些装置包括印刷电路板和PCR室。 PCR室是流体室，位于PC板中，或者位于PC板的一部分。 PC板可以包括带有温度传感器和控制器的线圈跟踪加热元件。
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72.发明申请公开(公告)号：US20160280537A1
公开(公告)日：2016-09-29
申请号：US15178512
申请日：2016-06-09
Applicant: CALIFORNIA INSTITUTE OF TECHNOLOGY
Inventor： Michael D. HENRY , Andrew P. HOMYK , Axel SCHERER , Thomas A. TOMBRELLO , Sameer WALAVALKAR
CPC classification number: B81C1/00111 , B01J19/0046 , B01J2219/00504 , B01J2219/00664 , B81B1/006 , B81B2203/0361 , B81B2207/056 , B81C2201/0112 , B81C2201/0132 , B81C2201/0133 , B81C2201/0159 , G01N1/405 , H01L21/3065 , H01L21/30655 , H01L21/3081 , H01L21/3086 , Y10T436/25375
Abstract: Methods for fabricating of high aspect ratio probes and deforming micropillars and nanopillars are described. Use of polymers in deforming nanopillars and micropillars is also described.
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公开(公告)号：US20160258942A1
公开(公告)日：2016-09-08
申请号：US15157346
申请日：2016-05-17
Applicant: CALIFORNIA INSTITUTE OF TECHNOLOGY
Inventor： Axel SCHERER , Samuel NJOROGE , Jingqing HUANG
IPC: G01N33/543 , G01N21/41 , A61B5/1459 , G01N33/552
CPC classification number: G01N33/566 , A61B5/1459 , A61B5/1491 , A61B2562/0233 , A61B2562/043 , G01N21/41 , G01N33/54373 , G01N33/552 , G01N2201/068 , G01N2201/08
Abstract: An implantable diagnostic device in accordance with the present disclosure provides various benefits such as a compact size thereby allowing implanting of the device inside animate objects; low cost due to incorporation of inexpensive detection circuitry and the use of conventional IC fabrication techniques; re-usability by heating thereby allowing multiple diagnostic tests to be performed without discarding the device; and a configuration that allows performing of simultaneous and/or sequential diagnostic tests for detecting one or more similar or dissimilar target molecules concurrently or at different times.
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公开(公告)号：US20160151782A1
公开(公告)日：2016-06-02
申请号：US14963180
申请日：2015-12-08
Applicant: CALIFORNIA INSTITUTE OF TECHNOLOGY
Inventor： Imran R. MALIK , Axel SCHERER
IPC: B01L3/00
CPC classification number: B01L3/502707 , B01L7/52 , B01L2200/027 , B01L2200/04 , B01L2200/0689 , B01L2200/10 , B01L2200/12 , B01L2300/0861 , B01L2300/0877 , B01L2300/0887 , B01L2300/16 , B29C65/486 , B32B3/02 , B32B3/30 , Y10T137/8593
Abstract: A fluidic device including a body having a surface and one or more channels located in the body. Recesses are defined on said surface. The one or more channels can have respective boundaries. A layer of adhesive including one or more panel-shaped pieces having a pattern based on the pattern of boundaries of the channels can be formed and applied on the surface of the body. It is further controlled that the layer of adhesive has respective boundaries surrounding the boundaries of the one or more channels.
Abstract translation: 一种流体装置，包括具有表面的主体和位于身体中的一个或多个通道。 凹槽被定义在所述表面上。 一个或多个通道可以具有相应的边界。 可以形成包括一个或多个基于通道边界图案的图案的一个或多个面板形件的粘合剂层，并施加到主体的表面上。 进一步控制粘合剂层具有围绕一个或多个通道的边界的相应边界。
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75.发明申请SURFACE ENHANCED RAMAN SPECTROSCOPY DETECTION OF GASES, PARTICLES AND LIQUIDS THROUGH NANOPILLAR STRUCTURES 有权通过纳米结构检测气体，颗粒和液体的表面增强拉曼光谱公开(公告)号：US20160069810A1
公开(公告)日：2016-03-10
申请号：US14621295
申请日：2015-02-12
Applicant: CALIFORNIA INSTITUTE OF TECHNOLOGY
Inventor： Sameer WALAVALKAR , Axel SCHERER , Thomas A. TOMBRELLO
IPC: G01N21/65 , G01N33/18 , G01N33/483 , G01N33/00
CPC classification number: G01N21/658 , A61B5/00 , A61B5/0031 , A61B5/14503 , A61B5/1455 , A61B5/14552 , A61B5/1459 , A61B5/686 , G01N33/0004 , G01N33/18 , G01N33/483
Abstract: Methods and systems for nanopillar sensors are described. Nanopillars can be defined on a substrate, and metal deposited on the nanopillars. A thermal treatment can reflow the metal on the nanopillars forming metallic bulbs on the top end of the nanopillars. These structures can have enhanced optical detection when functionalized with biological agents, or can detect gases, particles and liquids through interaction with the metal layer on the nanopillars.
Abstract translation: 描述了纳米柱传感器的方法和系统。 纳米玻璃可以在基底上定义，金属沉积在纳米柱上。 热处理可以回流纳米柱上的金属，在纳米柱的顶端形成金属灯泡。 这些结构可以在用生物制剂进行功能化时具有增强的光学检测，或者可以通过与纳米柱上的金属层相互作用来检测气体，颗粒和液体。
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Patent Agency Ranking
76.发明申请SILICON PHOTONIC CRYSTAL NANOBEAM CAVITY WITHOUT SURFACE CLADDING AND INTEGRATED WITH MICRO-HEATER FOR SENSING APPLICATIONS 审中-公开硅光电晶体纳米颗粒无表面贴合和集成微型加热器用于感应应用公开(公告)号：US20160025626A1
公开(公告)日：2016-01-28
申请号：US14801162
申请日：2015-07-16
Applicant: CALIFORNIA INSTITUTE OF TECHNOLOGY
Inventor： William DOS SANTOS FEGADOLLI , Axel SCHERER
CPC classification number: G01N21/7746 , G01N21/0332 , G01N2021/0346
Abstract: A silicon photonic crystal nanobeam cavity device is described, including a heater that can set a desired temperature on the cavity device in order to control its resonant wavelength. The device has no cladding, which is advantageous for sensing. Biosensing applications with temperature control can be carried out with the nanobeam cavity device.
Abstract translation: 描述了一种硅光子晶体纳米孔腔装置，其包括可以在空腔装置上设置所需温度以加热谐振波长的加热器。 该装置没有包层，这对于感测是有利的。 具有温度控制的生物传感应用可以使用nanobeam腔装置进行。
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公开(公告)号：US20150380989A1
公开(公告)日：2015-12-31
申请号：US14840819
申请日：2015-08-31
Applicant: CALIFORNIA INSTITUTE OF TECHNOLOGY
Inventor： Axel SCHERER , Aditya RAJAGOPAL , Seheon KIM , Andrew P. HOMYK
CPC classification number: H02J50/30 , A61B5/0017 , A61B5/6867 , A61B2560/0219 , G01J3/02 , G01J3/0218 , G01J3/0283 , G01N21/25 , H01L31/03529 , H01L31/0475 , H01L31/054 , H02J7/025 , H02J17/00 , H02J50/80 , H02S40/38 , H03F3/082 , H03F3/45183 , H03F2203/45702 , H04B10/807 , Y02E10/52
Abstract: The present disclosure describes a method for optically powering transducers and related transducers with a photovoltaic collector. An optical fiber power delivery method and a free space power delivery method are also provided. A fabrication process for making an optically powered transducer is further described, together with an implantable transducer system based on optical power delivery.
Abstract translation: 本公开描述了一种用于利用光伏收集器对换能器和相关换能器进行光学供电的方法。 还提供了光纤功率传递方法和自由空间功率传递方法。 进一步描述用于制造光学功率传感器的制造工艺，以及基于光功率传递的可植入传感器系统。
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公开(公告)号：US20140301418A1
公开(公告)日：2014-10-09
申请号：US14095372
申请日：2013-12-03
Applicant: CALIFORNIA INSTITUTE OF TECHNOLOGY
Inventor： Seheon KIM , Axel SCHERER
CPC classification number: H01S5/183 , B82Y20/00 , H01L31/0352 , H01L31/035281 , H01L33/0045 , H01L2933/0083 , H01S5/041 , H01S5/105 , H01S5/18319 , H01S5/18327 , H01S5/18352 , H01S5/34 , H01S5/3412 , Y02E10/50
Abstract: Photonic crystal cavities and related devices and methods are described. The described cavities can be used as lasers, photovoltaic sources, and single photon sources. The cavities can be both optically and electrically pumped. A fabrication process of the cavities is also described.
Abstract translation: 描述了光子晶体腔及相关装置和方法。 所描述的空腔可以用作激光器，光电源和单个光子源。 空腔可以光学和电气泵送。 还描述了空腔的制造工艺。
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公开(公告)号：US20140228660A1
公开(公告)日：2014-08-14
申请号：US14174827
申请日：2014-02-06
Applicant: California Institute of Technology
Inventor： Muhammad MUJEEB-U-RAHMAN , Axel SCHERER
IPC: A61B5/00 , A61B5/145 , A61B5/1473
CPC classification number: A61B5/0026 , A61B5/0031 , A61B5/14532 , A61B5/1473 , A61B5/14865 , A61B2560/0219 , A61B2562/0209 , A61B2562/028 , A61B2562/04 , A61B2562/125
Abstract: An implantable device having a communication system, a sensor, and a monolithic substrate is described. The monolithic substrate has an integrated sensor circuit configured to process input from the sensor into a form conveyable by the communication system.
Abstract translation: 描述了具有通信系统，传感器和单片基板的可植入装置。 单片基板具有集成的传感器电路，其被配置为将来自传感器的输入处理成可由通信系统传送的形式。
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80.发明申请公开(公告)号：US20140161386A1
公开(公告)日：2014-06-12
申请号：US14051409
申请日：2013-10-10
Applicant: CALIFORNIA INSTITUTE OF TECHNOLOGY
Inventor： William DOS SANTOS FEGADOLLI , Axel SCHERER
IPC: G02B6/12
CPC classification number: G02B6/1225 , B82Y20/00 , G02B6/107 , G02B6/1228
Abstract: Methods and devices for a tunable photonic crystal nanobeam cavity are disclosed. Such nanobeam cavity has high Q-factor and can be integrated with a microheater. The resonant wavelength of the cavity can be tuned to attain a high modulation depth with low power consumption.
Abstract translation: 公开了可调谐光子晶体纳米孔腔的方法和装置。 这样的纳米孔腔具有高Q因子，并且可以与微加热器结合。 可以调谐空腔的谐振波长以获得低功耗的高调制深度。
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