公开(公告)号：US20150268191A1

公开(公告)日：2015-09-24

申请号：US14673700

申请日：2015-03-30

Applicant: CALIFORNIA INSTITUTE OF TECHNOLOGY

Inventor： Andrew P. HOMYK ,  Michael D. HENRY ,  Axel SCHERER ,  Sameer WALAVALKAR

IPC: G01N27/414 ,  H01L29/06 ,  H01L29/66

CPC classification number: G01N27/4146 ,  B82Y10/00 ,  B82Y15/00 ,  H01L29/0676 ,  H01L29/66666 ,  H01L29/775

Abstract: Methods for fabricating silicon nanowire chemical sensing devices, devices thus obtained, and methods for utilizing devices for sensing and measuring chemical concentration of selected species in a fluid are described. Devices may comprise a metal-oxide-semiconductor field-effect transistor (MOSFET) structure.

Abstract translation: 描述了制造硅纳米线化学感测装置的方法，如此获得的装置，以及利用用于感测和测量流体中选定物种的化学浓度的装置的方法。 器件可以包括金属氧化物半导体场效应晶体管（MOSFET）结构。

公开(公告)号：US20150299757A1

公开(公告)日：2015-10-22

申请号：US14753741

申请日：2015-06-29

Applicant: CALIFORNIA INSTITUTE OF TECHNOLOGY

Inventor： Aditya RAJAGOPAL ,  Axel SCHERER ,  Michael D. HENRY ,  Sameer WALAVALKAR ,  Thomas A. TOMBRELLO ,  Andrew P. HOMYK

IPC: C12Q1/02

CPC classification number: C12Q1/02 ,  A61B5/04001 ,  G01N27/3275 ,  G01N27/4146 ,  G01R1/06711 ,  G01R1/07342 ,  H01L29/413 ,  H01L29/42376 ,  H01L29/4966 ,  H01L29/66477 ,  H01L29/78 ,  H01L29/7831

Abstract: The basic structure and functionality of a probe as disclosed herein allows for flexibly incorporating into the probe, various sensing elements for various sensing applications. Two example applications among these various sensing applications include bio-sensing and chemical-sensing applications. For bio-sensing applications the probe, which is fabricated upon a silicon substrate, includes a bio-sensing element such as a nano-pillar transistor, and for chemical-sensing applications the probe includes a sensing element that has a functionalized contact area whereby the sensing element generates a voltage when exposed to one or more chemicals of interest.

Abstract translation: 本文公开的探针的基本结构和功能允许灵活地并入到探针中，用于各种感测应用的各种感测元件。 这些各种感测应用中的两个示例应用包括生物感测和化学感测应用。 对于生物感测应用，制造在硅衬底上的探针包括诸如纳米柱晶体管的生物感测元件，并且对于化学感测应用，探针包括具有功能化接触区域的感测元件， 当暴露于感兴趣的一种或多种化学品时，感测元件产生电压。

公开(公告)号：US20140319459A1

公开(公告)日：2014-10-30

申请号：US14329748

申请日：2014-07-11

Applicant: CALIFORNIA INSTITUTE OF TECHNOLOGY

Inventor： Andrew P. HOMYK ,  Michael D. HENRY ,  Axel SCHERER ,  Sameer WALAVALKAR

IPC: H01L29/06 ,  H01L31/0352 ,  H01L33/06

CPC classification number: H01L31/035227 ,  B82Y10/00 ,  B82Y40/00 ,  H01L21/02381 ,  H01L21/0243 ,  H01L21/02521 ,  H01L21/0259 ,  H01L21/02639 ,  H01L29/0665 ,  H01L29/0676 ,  H01L29/127 ,  H01L29/267 ,  H01L29/413 ,  H01L29/66439 ,  H01L29/775 ,  H01L33/06 ,  Y10S977/762

Abstract: Methods for fabricating self-aligned heterostructures and semiconductor arrangements using silicon nanowires are described.

Abstract translation: 描述了使用硅纳米线制造自对准异质结构和半导体布置的方法。

公开(公告)号：US20140341591A1

公开(公告)日：2014-11-20

申请号：US14306813

申请日：2014-06-17

Applicant: CALIFORNIA INSTITUTE OF TECHNOLOGY

Inventor： Axel SCHERER ,  Aditya RAJAGOPAL ,  Seheon KIM ,  Andrew P. HOMYK

IPC: H04B10/80 ,  G01J3/02

CPC classification number: H02J50/30 ,  A61B5/0017 ,  A61B5/6867 ,  A61B2560/0219 ,  G01J3/02 ,  G01J3/0218 ,  G01J3/0283 ,  G01N21/25 ,  H01L31/03529 ,  H01L31/0475 ,  H01L31/054 ,  H02J7/025 ,  H02J17/00 ,  H02J50/80 ,  H02S40/38 ,  H03F3/082 ,  H03F3/45183 ,  H03F2203/45702 ,  H04B10/807 ,  Y02E10/52

Abstract: The present disclosure describes an optically powered transducer with a photovoltaic collector. An optical fiber power delivery method and system and a free space power delivery method are also provided. A fabrication process for making an optically powered transducer is further described, together with an implantable transducer system based on optical power delivery.

Abstract translation: 本公开描述了具有光伏收集器的光学功率传感器。 还提供了光纤功率传递方法和系统以及自由空间功率传递方法。 进一步描述用于制造光学功率传感器的制造工艺，以及基于光功率传递的可植入传感器系统。

公开(公告)号：US20150050746A1

公开(公告)日：2015-02-19

申请号：US14527039

申请日：2014-10-29

Applicant: CALIFORNIA INSTITUTE OF TECHNOLOGY

Inventor： Michael D. HENRY ,  Andrew P. HOMYK ,  Axel SCHERER ,  Thomas A. TOMBRELLO ,  Sameer WALAVALKAR

IPC: G01N1/40

CPC classification number: B81C1/00111 ,  B01J19/0046 ,  B01J2219/00504 ,  B01J2219/00664 ,  B81B1/006 ,  B81B2203/0361 ,  B81B2207/056 ,  B81C2201/0112 ,  B81C2201/0132 ,  B81C2201/0133 ,  B81C2201/0159 ,  G01N1/405 ,  H01L21/3065 ,  H01L21/30655 ,  H01L21/3081 ,  H01L21/3086 ,  Y10T436/25375

Abstract: Methods for fabricating of high aspect ratio probes and deforming micropillars and nanopillars are described. Use of polymers in deforming nanopillars and micropillars is also described.

Abstract translation: 描述了制造高纵横比探针和变形微柱和纳米柱的方法。 还描述了聚合物在变形纳米柱和微柱体中的使用。

公开(公告)号：US20140357974A1

公开(公告)日：2014-12-04

申请号：US14463392

申请日：2014-08-19

Applicant: CALIFORNIA INSTITUTE OF TECHNOLOGY

Inventor： Aditya RAJAGOPAL ,  Axel SCHERER ,  Michael D. HENRY ,  Sameer WALAVALKAR ,  Thomas A. TOMBRELLO ,  Andrew P. HOMYK

IPC: H01L29/423 ,  A61B5/04 ,  H01L29/49 ,  H01L29/78 ,  H01L29/41

CPC classification number: C12Q1/02 ,  A61B5/04001 ,  G01N27/3275 ,  G01N27/4146 ,  G01R1/06711 ,  G01R1/07342 ,  H01L29/413 ,  H01L29/42376 ,  H01L29/4966 ,  H01L29/66477 ,  H01L29/78 ,  H01L29/7831

Abstract: A field effect nano-pillar transistor has a pillar shaped gate element incorporating a biomimitec portion that provides various advantages over prior art devices. The small size of the nano-pillar transistor allows for advantageous insertion into cellular membranes, and the biomimitec character of the gate element operates as an advantageous interface for sensing small amplitude voltages such as transmembrane cell potentials. The nano-pillar transistor can be used in various embodiments to stimulate cells, to measure cell response, or to perform a combination of both actions.

公开(公告)号：US20140070286A1

公开(公告)日：2014-03-13

申请号：US13852480

申请日：2013-03-28

Applicant: California Institute of Technology

Inventor： Aditya RAJAGOPAL ,  Axel SCHERER ,  Michael D. HENRY ,  Sameer WALAVALKAR ,  Thomas A. TOMBRELLO ,  Andrew P. HOMYK

IPC: H01L29/78 ,  H01L29/66

CPC classification number: C12Q1/02 ,  A61B5/04001 ,  G01N27/3275 ,  G01N27/4146 ,  G01R1/06711 ,  G01R1/07342 ,  H01L29/413 ,  H01L29/42376 ,  H01L29/4966 ,  H01L29/66477 ,  H01L29/78 ,  H01L29/7831

Abstract: A field effect nano-pillar transistor has a pillar shaped gate element incorporating a biomimitec portion that provides various advantages over prior art devices. The small size of the nano-pillar transistor allows for advantageous insertion into cellular membranes, and the biomimitec character of the gate element operates as an advantageous interface for sensing small amplitude voltages such as transmembrane cell potentials. The nano-pillar transistor can be used in various embodiments to stimulate cells, to measure cell response, or to perform a combination of both actions.

Abstract translation: 场效应纳米柱晶体管具有结合有生物医学部分的柱形门元件，其提供了优于现有技术器件的各种优点。 纳米柱晶体管的小尺寸允许有利地插入到细胞膜中，并且栅极元件的生物学特性作为用于感测小幅度电压（例如跨膜电池电位）的有利接口。 纳米柱晶体管可用于各种实施例中以刺激细胞，测量细胞反应或执行两种动作的组合。

公开(公告)号：US20160280537A1

公开(公告)日：2016-09-29

申请号：US15178512

申请日：2016-06-09

Applicant: CALIFORNIA INSTITUTE OF TECHNOLOGY

Inventor： Michael D. HENRY ,  Andrew P. HOMYK ,  Axel SCHERER ,  Thomas A. TOMBRELLO ,  Sameer WALAVALKAR

IPC: B81C1/00 ,  B81B1/00 ,  B01J19/00

CPC classification number: B81C1/00111 ,  B01J19/0046 ,  B01J2219/00504 ,  B01J2219/00664 ,  B81B1/006 ,  B81B2203/0361 ,  B81B2207/056 ,  B81C2201/0112 ,  B81C2201/0132 ,  B81C2201/0133 ,  B81C2201/0159 ,  G01N1/405 ,  H01L21/3065 ,  H01L21/30655 ,  H01L21/3081 ,  H01L21/3086 ,  Y10T436/25375

Abstract: Methods for fabricating of high aspect ratio probes and deforming micropillars and nanopillars are described. Use of polymers in deforming nanopillars and micropillars is also described.

公开(公告)号：US20150380989A1

公开(公告)日：2015-12-31

申请号：US14840819

申请日：2015-08-31

Applicant: CALIFORNIA INSTITUTE OF TECHNOLOGY

Inventor： Axel SCHERER ,  Aditya RAJAGOPAL ,  Seheon KIM ,  Andrew P. HOMYK

IPC: H02J17/00 ,  G01J3/02

CPC classification number: H02J50/30 ,  A61B5/0017 ,  A61B5/6867 ,  A61B2560/0219 ,  G01J3/02 ,  G01J3/0218 ,  G01J3/0283 ,  G01N21/25 ,  H01L31/03529 ,  H01L31/0475 ,  H01L31/054 ,  H02J7/025 ,  H02J17/00 ,  H02J50/80 ,  H02S40/38 ,  H03F3/082 ,  H03F3/45183 ,  H03F2203/45702 ,  H04B10/807 ,  Y02E10/52

Abstract: The present disclosure describes a method for optically powering transducers and related transducers with a photovoltaic collector. An optical fiber power delivery method and a free space power delivery method are also provided. A fabrication process for making an optically powered transducer is further described, together with an implantable transducer system based on optical power delivery.

Abstract translation: 本公开描述了一种用于利用光伏收集器对换能器和相关换能器进行光学供电的方法。 还提供了光纤功率传递方法和自由空间功率传递方法。 进一步描述用于制造光学功率传感器的制造工艺，以及基于光功率传递的可植入传感器系统。

公开(公告)号：US20140072993A1

公开(公告)日：2014-03-13

申请号：US13852476

申请日：2013-03-28

Applicant: CALIFORNIA INSTITUTE OF TECHNOLOGY

Inventor： Aditya RAJAGOPAL ,  Axel SCHERER ,  Michael D. HENRY ,  Sameer WALAVALKAR ,  Thomas A. TOMBRELLO ,  Andrew P. HOMYK

IPC: G01N27/327

CPC classification number: C12Q1/02 ,  A61B5/04001 ,  G01N27/3275 ,  G01N27/4146 ,  G01R1/06711 ,  G01R1/07342 ,  H01L29/413 ,  H01L29/42376 ,  H01L29/4966 ,  H01L29/66477 ,  H01L29/78 ,  H01L29/7831

Abstract: The basic structure and functionality of a probe as disclosed herein allows for flexibly incorporating into the probe, various sensing elements for various sensing applications. Two example applications among these various sensing applications include bio-sensing and chemical-sensing applications. For bio-sensing applications the probe, which is fabricated upon a silicon substrate, includes a bio-sensing element such as a nano-pillar transistor, and for chemical-sensing applications the probe includes a sensing element that has a functionalized contact area whereby the sensing element generates a voltage when exposed to one or more chemicals of interest.

Abstract translation: 本文公开的探针的基本结构和功能允许灵活地并入到探针中，用于各种感测应用的各种感测元件。 这些各种感测应用中的两个示例应用包括生物感测和化学感测应用。 对于生物感测应用，制造在硅衬底上的探针包括诸如纳米柱晶体管的生物感测元件，并且对于化学感测应用，探针包括具有功能化接触区域的感测元件， 当暴露于感兴趣的一种或多种化学品时，感测元件产生电压。